메뉴 건너뛰기




Volumn 1800, Issue 10, 2010, Pages 1145-1152

Are optimal levels of testosterone associated with better cognitive function in healthy older women and men?

Author keywords

Cognition; Estrogen; Sex hormone binding globulin; Testosterone; Thyroid hormones

Indexed keywords

ESTROGEN; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; THYROID HORMONE;

EID: 77956169573     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2009.12.009     Document Type: Article
Times cited : (45)

References (63)
  • 1
    • 0031872077 scopus 로고    scopus 로고
    • Rethinking estrogen and the brain
    • Barrett-Connor E. Rethinking estrogen and the brain. JAGS 1998, 46:918-920.
    • (1998) JAGS , vol.46 , pp. 918-920
    • Barrett-Connor, E.1
  • 2
    • 0038386058 scopus 로고    scopus 로고
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women
    • Shumaker S.A., Legault C., Rapp S.R., et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. JAMA 2003, 289:2651-2662.
    • (2003) JAMA , vol.289 , pp. 2651-2662
    • Shumaker, S.A.1    Legault, C.2    Rapp, S.R.3
  • 3
    • 2942755831 scopus 로고    scopus 로고
    • Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study
    • Shumaker S.A., Legault C., Kuller L., et al. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. JAMA 2004, 291(24):2947-2958.
    • (2004) JAMA , vol.291 , Issue.24 , pp. 2947-2958
    • Shumaker, S.A.1    Legault, C.2    Kuller, L.3
  • 5
    • 52049083656 scopus 로고    scopus 로고
    • The healthy cell bias of estrogen action
    • Brinton R.D. The healthy cell bias of estrogen action. Trends Neurosci. 2008, 31(10):529-537.
    • (2008) Trends Neurosci. , vol.31 , Issue.10 , pp. 529-537
    • Brinton, R.D.1
  • 6
    • 0035936944 scopus 로고    scopus 로고
    • Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism
    • Ahlbom E., Prins G.S., Ceccatelli S. Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism. Brain Res. 2001, 892:255-262.
    • (2001) Brain Res. , vol.892 , pp. 255-262
    • Ahlbom, E.1    Prins, G.S.2    Ceccatelli, S.3
  • 7
    • 0035006622 scopus 로고    scopus 로고
    • Testosterone mediated neuroprotection through the androgen receptor in human primary neurons
    • Hammond J., Le Q., Goodyer C., Gelfand M., Trifiro M., LeBlanc A. Testosterone mediated neuroprotection through the androgen receptor in human primary neurons. J. Neurochem. 2001, 77:1319-1326.
    • (2001) J. Neurochem. , vol.77 , pp. 1319-1326
    • Hammond, J.1    Le, Q.2    Goodyer, C.3    Gelfand, M.4    Trifiro, M.5    LeBlanc, A.6
  • 8
    • 0035900185 scopus 로고    scopus 로고
    • Testosterone attenuates b-amyloid toxicity in cultured hippocampal neurons
    • Pike C.J. Testosterone attenuates b-amyloid toxicity in cultured hippocampal neurons. Brain Res. 2001, 919:160-165.
    • (2001) Brain Res. , vol.919 , pp. 160-165
    • Pike, C.J.1
  • 9
    • 84927044774 scopus 로고    scopus 로고
    • Testosterone, gonadotrophins, & genetic polymorphisms in men with Alzheimer's disease
    • Cambridge University Press, Cambridge, E. Hogervorst, V.W. Henderson, R.D. Brinton-Diaz, R. Gibbs (Eds.)
    • Hogervorst E., Bandelow S., Lehmann D.L. Testosterone, gonadotrophins, & genetic polymorphisms in men with Alzheimer's disease. Hormones, Cognition and the Brain 2009, Cambridge University Press, Cambridge. E. Hogervorst, V.W. Henderson, R.D. Brinton-Diaz, R. Gibbs (Eds.).
    • (2009) Hormones, Cognition and the Brain
    • Hogervorst, E.1    Bandelow, S.2    Lehmann, D.L.3
  • 10
    • 84927029810 scopus 로고    scopus 로고
    • Testosterone regulates Alzheimer's disease pathogenesis
    • Cambridge University Press, Cambridge, Chapter 26, E. Hogervorst, V.W. Henderson, R.D. Brinton-Diaz, R. Gibbs (Eds.)
    • Pike C.J., Rosario E.R. Testosterone regulates Alzheimer's disease pathogenesis. Hormones, Cognition and the Brain 2009, Cambridge University Press, Cambridge, Chapter 26. E. Hogervorst, V.W. Henderson, R.D. Brinton-Diaz, R. Gibbs (Eds.).
    • (2009) Hormones, Cognition and the Brain
    • Pike, C.J.1    Rosario, E.R.2
  • 11
    • 26844559338 scopus 로고    scopus 로고
    • Increasing testosterone levels and effects on cognitive function in elderly men and women
    • Hogervorst E., Bandelow S., Moffat S.D. Increasing testosterone levels and effects on cognitive function in elderly men and women. Curr. Drugs Targets: CNS Neurol. Dis. 2005, 4(5):531-540.
    • (2005) Curr. Drugs Targets: CNS Neurol. Dis. , vol.4 , Issue.5 , pp. 531-540
    • Hogervorst, E.1    Bandelow, S.2    Moffat, S.D.3
  • 12
    • 0345708069 scopus 로고    scopus 로고
    • Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women
    • Hogervorst E., De Jager C., Budge M.M., Smith A.D. Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women. Psychoneuroendocrinology 2004, 29(3):405-421.
    • (2004) Psychoneuroendocrinology , vol.29 , Issue.3 , pp. 405-421
    • Hogervorst, E.1    De Jager, C.2    Budge, M.M.3    Smith, A.D.4
  • 14
    • 0033304659 scopus 로고    scopus 로고
    • Endogenous sex hormones and cognitive function in older men
    • Barrett-Connor E., Goodman-Gruen D., Patay B. Endogenous sex hormones and cognitive function in older men. JCEM 1999, 84(10):3681-3685.
    • (1999) JCEM , vol.84 , Issue.10 , pp. 3681-3685
    • Barrett-Connor, E.1    Goodman-Gruen, D.2    Patay, B.3
  • 15
    • 0036218209 scopus 로고    scopus 로고
    • Sex hormones and cognitive function in older men
    • Yaffe K., Lui L.Y., Zmuda J., Cauley J. Sex hormones and cognitive function in older men. JAGS 2002, 50(4):707-712.
    • (2002) JAGS , vol.50 , Issue.4 , pp. 707-712
    • Yaffe, K.1    Lui, L.Y.2    Zmuda, J.3    Cauley, J.4
  • 16
    • 33646189208 scopus 로고    scopus 로고
    • The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90year-old men and women
    • Thilers P.P., Macdonald S.W., Herlitz A. The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90year-old men and women. Psychoneuroendocrinology 2006, 31(5):565-576.
    • (2006) Psychoneuroendocrinology , vol.31 , Issue.5 , pp. 565-576
    • Thilers, P.P.1    Macdonald, S.W.2    Herlitz, A.3
  • 17
    • 18244398191 scopus 로고    scopus 로고
    • Age, hormones, and cognitive functioning among middle-aged and elderly men: cross-sectional evidence from the Massachusetts Male Aging Study
    • Fonda S.J., Bertrand R., O'Donnell A., Longcope C., McKinlay J.B. Age, hormones, and cognitive functioning among middle-aged and elderly men: cross-sectional evidence from the Massachusetts Male Aging Study. J. Gerontol. A Biol. Sci. Med. Sci. 2005, 60(3):385-390.
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci. , vol.60 , Issue.3 , pp. 385-390
    • Fonda, S.J.1    Bertrand, R.2    O'Donnell, A.3    Longcope, C.4    McKinlay, J.B.5
  • 18
    • 33746429635 scopus 로고    scopus 로고
    • Negative association of testosterone on spatial visualization in 35 to 80year old men
    • Yonker J.E., Eriksson E., Nilsson L.G., Herlitz A. Negative association of testosterone on spatial visualization in 35 to 80year old men. Cortex 2006, 42(3):376-386.
    • (2006) Cortex , vol.42 , Issue.3 , pp. 376-386
    • Yonker, J.E.1    Eriksson, E.2    Nilsson, L.G.3    Herlitz, A.4
  • 19
    • 34249105649 scopus 로고    scopus 로고
    • Testosterone and cognitive function in ageing men: data from the Florey Adelaide Male Ageing Study (FAMAS)
    • Martin D.M., Wittert G., Burns N.R., Haren M.T., Sugarman R. Testosterone and cognitive function in ageing men: data from the Florey Adelaide Male Ageing Study (FAMAS). Maturitas 2007, 57(2):182-194.
    • (2007) Maturitas , vol.57 , Issue.2 , pp. 182-194
    • Martin, D.M.1    Wittert, G.2    Burns, N.R.3    Haren, M.T.4    Sugarman, R.5
  • 20
    • 18844376325 scopus 로고    scopus 로고
    • Endogenous sex hormone levels and cognitive function in aging men: is there an optimal level
    • Muller M., Aleman A., Grobbee D.E., deHaan E.H., van der Schouw Y.T. Endogenous sex hormone levels and cognitive function in aging men: is there an optimal level. JCEM 2005, 90(5):2618-2623.
    • (2005) JCEM , vol.90 , Issue.5 , pp. 2618-2623
    • Muller, M.1    Aleman, A.2    Grobbee, D.E.3    deHaan, E.H.4    van der Schouw, Y.T.5
  • 21
    • 33845481822 scopus 로고    scopus 로고
    • Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort
    • Yaffe K., Barnes D., Lindquist K., et al. Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort. Neurobiol. Aging 2007, 28(2):171-178.
    • (2007) Neurobiol. Aging , vol.28 , Issue.2 , pp. 171-178
    • Yaffe, K.1    Barnes, D.2    Lindquist, K.3
  • 22
    • 33749501951 scopus 로고    scopus 로고
    • Endogenous sex hormones, cognitive decline, and future dementia in old men
    • Geerlings M.I., Strozyk D., Masaki K., et al. Endogenous sex hormones, cognitive decline, and future dementia in old men. Ann. Neurol. 2006, 60(3):346-355.
    • (2006) Ann. Neurol. , vol.60 , Issue.3 , pp. 346-355
    • Geerlings, M.I.1    Strozyk, D.2    Masaki, K.3
  • 23
    • 28044432960 scopus 로고    scopus 로고
    • Association of sex steroid hormones with brain morphology and cognition in healthy elderly men
    • Lessov-Schlaggar C.N., Reed T., Swan G.E., et al. Association of sex steroid hormones with brain morphology and cognition in healthy elderly men. Neurology 2005, 65(10):1591-1596.
    • (2005) Neurology , vol.65 , Issue.10 , pp. 1591-1596
    • Lessov-Schlaggar, C.N.1    Reed, T.2    Swan, G.E.3
  • 24
    • 0036845350 scopus 로고    scopus 로고
    • Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men
    • Moffat S.D., Zonderman A.B., Metter E.J., Blackman M.R., Harman S.M., Resnick S.M. Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. JCEM 2002, 87(11):5001-5007.
    • (2002) JCEM , vol.87 , Issue.11 , pp. 5001-5007
    • Moffat, S.D.1    Zonderman, A.B.2    Metter, E.J.3    Blackman, M.R.4    Harman, S.M.5    Resnick, S.M.6
  • 25
    • 0036251660 scopus 로고    scopus 로고
    • Endogenous estradiol and testosterone levels are associated with cognitive performance in older women and men
    • May
    • Wolf O.T., Kirschbaum C. Endogenous estradiol and testosterone levels are associated with cognitive performance in older women and men. Horm. Behav. May 2002, 41(3):259-266.
    • (2002) Horm. Behav , vol.41 , Issue.3 , pp. 259-266
    • Wolf, O.T.1    Kirschbaum, C.2
  • 27
    • 0031959352 scopus 로고    scopus 로고
    • Cognitive function and dementia in six areas of England and Wales: the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study. The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
    • MRC CFAS
    • Cognitive function and dementia in six areas of England and Wales: the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study. The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Psychol. Med. 1998, 28(2):319-335. MRC CFAS.
    • (1998) Psychol. Med. , vol.28 , Issue.2 , pp. 319-335
  • 28
    • 1642503822 scopus 로고    scopus 로고
    • Neutrophil counts, monocyte counts and cardiovascular disease in the elderly
    • Pinto E.M., Huppert F.A., Morgan K., CFAS M.R.C., Brayne C. Neutrophil counts, monocyte counts and cardiovascular disease in the elderly. Exp. Gerontol. 1998, 39(4):615-619.
    • (1998) Exp. Gerontol. , vol.39 , Issue.4 , pp. 615-619
    • Pinto, E.M.1    Huppert, F.A.2    Morgan, K.3    CFAS, M.R.C.4    Brayne, C.5
  • 29
    • 0016823810 scopus 로고
    • 'Mini-mental State': a practical method for grading the cognitive state of patients for the clinician
    • Folstein M., Folstein S., McHugh P. 'Mini-mental State': a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 1977, 12:189-198.
    • (1977) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.1    Folstein, S.2    McHugh, P.3
  • 30
    • 0022580368 scopus 로고
    • A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT
    • Copeland J.R., Dewey M.E., Griffiths-Jones H.M. A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT. Psychol. Med. 1986, 16:89-99.
    • (1986) Psychol. Med. , vol.16 , pp. 89-99
    • Copeland, J.R.1    Dewey, M.E.2    Griffiths-Jones, H.M.3
  • 32
    • 48149103375 scopus 로고    scopus 로고
    • Thyroid function and cognitive decline in the MRC Cognitive Function and Ageing Study
    • Hogervorst E., Huppert F., Matthews F.E., Brayne C. Thyroid function and cognitive decline in the MRC Cognitive Function and Ageing Study. Psychoneuroendocrinology 2008, 33(7):1013-1022.
    • (2008) Psychoneuroendocrinology , vol.33 , Issue.7 , pp. 1013-1022
    • Hogervorst, E.1    Huppert, F.2    Matthews, F.E.3    Brayne, C.4
  • 34
    • 29344447069 scopus 로고    scopus 로고
    • Evaluation of automated SHBG immunoassays
    • Jin M., Wener M.H., Bankson D.D. Evaluation of automated SHBG immunoassays. Clin. Biochem. 2006, 39(1):91-94.
    • (2006) Clin. Biochem. , vol.39 , Issue.1 , pp. 91-94
    • Jin, M.1    Wener, M.H.2    Bankson, D.D.3
  • 35
    • 4043121959 scopus 로고    scopus 로고
    • Predictors of cognitive change from preclinical to clinical Alzheimer's disease
    • Jones S., Small B.J., Fraiglioni L., Backman L. Predictors of cognitive change from preclinical to clinical Alzheimer's disease. Brain Cogn. 2002, 49(2):210-213.
    • (2002) Brain Cogn. , vol.49 , Issue.2 , pp. 210-213
    • Jones, S.1    Small, B.J.2    Fraiglioni, L.3    Backman, L.4
  • 37
    • 33846991956 scopus 로고    scopus 로고
    • Position statement: utility, limitations and pitfalls in measuring testosterone: an endocrine society position statement
    • Rosner W., Auchus R.J., Azziz R., Sluss P.M., Raff H. Position statement: utility, limitations and pitfalls in measuring testosterone: an endocrine society position statement. JCEM 2007, 92(2):405-413.
    • (2007) JCEM , vol.92 , Issue.2 , pp. 405-413
    • Rosner, W.1    Auchus, R.J.2    Azziz, R.3    Sluss, P.M.4    Raff, H.5
  • 38
    • 59849111126 scopus 로고    scopus 로고
    • Current guidelines for the diagnosis of testosterone deficiency
    • Arver S., Lehtihet M. Current guidelines for the diagnosis of testosterone deficiency. Front. Horm. Res. 2009, 37:5-20.
    • (2009) Front. Horm. Res. , vol.37 , pp. 5-20
    • Arver, S.1    Lehtihet, M.2
  • 39
    • 0032692942 scopus 로고    scopus 로고
    • Cognitive function and endogenous sex hormones in older women
    • Barrett-Connor E., Goodman-Gruen D. Cognitive function and endogenous sex hormones in older women. JAGS 1999, 47(11):1289-1293.
    • (1999) JAGS , vol.47 , Issue.11 , pp. 1289-1293
    • Barrett-Connor, E.1    Goodman-Gruen, D.2
  • 40
    • 33947611967 scopus 로고    scopus 로고
    • Meta-analyses of the effect of hormone treatment on cognitive function in postmenopausal women
    • Yesufu A., Bandelow S., Hogervorst E. Meta-analyses of the effect of hormone treatment on cognitive function in postmenopausal women. Women's Health 2007, 3(2):173-195.
    • (2007) Women's Health , vol.3 , Issue.2 , pp. 173-195
    • Yesufu, A.1    Bandelow, S.2    Hogervorst, E.3
  • 42
    • 34948833099 scopus 로고    scopus 로고
    • Should surgically menopausal women be treated with estrogens to decrease the risk for dementia? Invited editorial
    • Hogervorst E., Bandelow S. Should surgically menopausal women be treated with estrogens to decrease the risk for dementia? Invited editorial. Neurology 2007, 69(11):1070-1071.
    • (2007) Neurology , vol.69 , Issue.11 , pp. 1070-1071
    • Hogervorst, E.1    Bandelow, S.2
  • 43
    • 0034114486 scopus 로고    scopus 로고
    • An association of elevated serum gonadotropin concentrations and Alzheimer Disease?
    • Apr
    • Bowen R.L., Isley J.P., Atkinson R.L. An association of elevated serum gonadotropin concentrations and Alzheimer Disease?. J. Neuroendocrinol. Apr 2000, 12(4):351-354.
    • (2000) J. Neuroendocrinol , vol.12 , Issue.4 , pp. 351-354
    • Bowen, R.L.1    Isley, J.P.2    Atkinson, R.L.3
  • 44
    • 0037010296 scopus 로고    scopus 로고
    • Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology
    • Bowen R.L., Smith M.A., Harris P.L., et al. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. J. Neurosci. Res. 2002, 70(3):514-518.
    • (2002) J. Neurosci. Res. , vol.70 , Issue.3 , pp. 514-518
    • Bowen, R.L.1    Smith, M.A.2    Harris, P.L.3
  • 45
    • 2442515246 scopus 로고    scopus 로고
    • Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition
    • Bowen R.L., Verdile G., Liu T., et al. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. J. Biol. Chem. 2004, 279(19):20539-20545.
    • (2004) J. Biol. Chem. , vol.279 , Issue.19 , pp. 20539-20545
    • Bowen, R.L.1    Verdile, G.2    Liu, T.3
  • 46
    • 14844331838 scopus 로고    scopus 로고
    • Evidence for the role of gonadotropin hormones in the development of Alzheimer disease
    • Feb
    • Casadesus G., Atwood C.S., Zhu X., et al. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cell. Mol. Life Sci. Feb 2005, 62(3):293-298.
    • (2005) Cell. Mol. Life Sci , vol.62 , Issue.3 , pp. 293-298
    • Casadesus, G.1    Atwood, C.S.2    Zhu, X.3
  • 47
    • 33947593994 scopus 로고    scopus 로고
    • Increases in LH are associated with declines in cognitive performance
    • Casadesus G., Milliken E.L., Webber K.M., et al. Increases in LH are associated with declines in cognitive performance. Mol. Cell Endocrinol. 2007, 169(1-2):107-111.
    • (2007) Mol. Cell Endocrinol. , vol.169 , Issue.1-2 , pp. 107-111
    • Casadesus, G.1    Milliken, E.L.2    Webber, K.M.3
  • 49
    • 0842347346 scopus 로고    scopus 로고
    • Free testosterone and risk for Alzheimer disease in older men
    • Moffat S.D., Zonderman A.B., Metter E.J., et al. Free testosterone and risk for Alzheimer disease in older men. Neurology 2004, 62(2):188-193.
    • (2004) Neurology , vol.62 , Issue.2 , pp. 188-193
    • Moffat, S.D.1    Zonderman, A.B.2    Metter, E.J.3
  • 52
    • 9644267082 scopus 로고    scopus 로고
    • Low free testosterone is an independent risk factor for AD
    • Hogervorst E., Bandelow S., Combrinck M.C., Smith A.D. Low free testosterone is an independent risk factor for AD. Exp. Gerontol. 2004, 39(11-12):1633-1639.
    • (2004) Exp. Gerontol. , vol.39 , Issue.11-12 , pp. 1633-1639
    • Hogervorst, E.1    Bandelow, S.2    Combrinck, M.C.3    Smith, A.D.4
  • 53
  • 54
    • 34948873567 scopus 로고    scopus 로고
    • Endogenous sex hormones as risk factors for dementia in elderly men and women
    • Ravaglia G., Forti P., Maiolo F., et al. Endogenous sex hormones as risk factors for dementia in elderly men and women. J. Gerontol. A Biol. Sci. Med. Sci. 2007, 62(9):1035-1041.
    • (2007) J. Gerontol. A Biol. Sci. Med. Sci. , vol.62 , Issue.9 , pp. 1035-1041
    • Ravaglia, G.1    Forti, P.2    Maiolo, F.3
  • 55
    • 0037320311 scopus 로고    scopus 로고
    • Higher estrogen levels are not associated with larger hippocampi and better memory performance
    • Den Heijer T., Geerlings M.I., Hofman A., et al. Higher estrogen levels are not associated with larger hippocampi and better memory performance. Arch. Neurol. 2003, 60(2):213-220.
    • (2003) Arch. Neurol. , vol.60 , Issue.2 , pp. 213-220
    • Den Heijer, T.1    Geerlings, M.I.2    Hofman, A.3
  • 57
    • 4544370855 scopus 로고    scopus 로고
    • Age-related testosterone depletion and the development of Alzheimer disease
    • Sep 22
    • Rosario E.R., Chang L., Stanczyk F.Z., Pike C.J. Age-related testosterone depletion and the development of Alzheimer disease. JAMA Sep 22 2004, 292(12):1431-1432.
    • (2004) JAMA , vol.292 , Issue.12 , pp. 1431-1432
    • Rosario, E.R.1    Chang, L.2    Stanczyk, F.Z.3    Pike, C.J.4
  • 58
    • 1842580609 scopus 로고    scopus 로고
    • Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease
    • Iivonen S., Corder E., Lehtovirta M., et al. Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease. Neurology 2004, 62(7):1170-1176.
    • (2004) Neurology , vol.62 , Issue.7 , pp. 1170-1176
    • Iivonen, S.1    Corder, E.2    Lehtovirta, M.3
  • 59
    • 0032786806 scopus 로고    scopus 로고
    • Evidence that the CAG repeat in the AR gene is associated with the age-related decline in serum androgen levels in men
    • Krithivas L., Yurgalevitch S.M., Mohr B.A., et al. Evidence that the CAG repeat in the AR gene is associated with the age-related decline in serum androgen levels in men. J. Endocrin. 1999, 162(1):137-142.
    • (1999) J. Endocrin. , vol.162 , Issue.1 , pp. 137-142
    • Krithivas, L.1    Yurgalevitch, S.M.2    Mohr, B.A.3
  • 60
    • 0347755468 scopus 로고    scopus 로고
    • The androgen receptor CAG repeat and serum testosterone in the risk of Alzheimer's disease in men
    • Lehmann D.J., Hogervorst E., Warden D.R., Smith A.D., Butler H.T., Ragoussis J. The androgen receptor CAG repeat and serum testosterone in the risk of Alzheimer's disease in men. JNNP 2004, 75(1):163-164.
    • (2004) JNNP , vol.75 , Issue.1 , pp. 163-164
    • Lehmann, D.J.1    Hogervorst, E.2    Warden, D.R.3    Smith, A.D.4    Butler, H.T.5    Ragoussis, J.6
  • 61
    • 0036771739 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 and testosterone interact in the risk of Alzheimer's disease in men
    • Hogervorst E., Lehmann D.J., Warden D.R., McBroom J., Smith A.D. Apolipoprotein E epsilon4 and testosterone interact in the risk of Alzheimer's disease in men. Int. J. Geriatr. Psychiatry 2002, 17(10):938-940.
    • (2002) Int. J. Geriatr. Psychiatry , vol.17 , Issue.10 , pp. 938-940
    • Hogervorst, E.1    Lehmann, D.J.2    Warden, D.R.3    McBroom, J.4    Smith, A.D.5
  • 62
    • 67649305069 scopus 로고    scopus 로고
    • The prevention of dementia
    • Peters R. The prevention of dementia. Int. J. Geriatr. Psychiatry 2009, 24(5):452-458.
    • (2009) Int. J. Geriatr. Psychiatry , vol.24 , Issue.5 , pp. 452-458
    • Peters, R.1
  • 63
    • 0036671817 scopus 로고    scopus 로고
    • Prevalence of dementia in users of hormone replacement therapy as defined by prescription data
    • Aug
    • Petitti D.B., Buckwalter J.G., Crooks V.C., Chiu V. Prevalence of dementia in users of hormone replacement therapy as defined by prescription data. J. Gerontol. A Biol. Sci. Med. Sci. Aug 2002, 57(8):M532-M538.
    • (2002) J. Gerontol. A Biol. Sci. Med. Sci. , vol.57 , Issue.8
    • Petitti, D.B.1    Buckwalter, J.G.2    Crooks, V.C.3    Chiu, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.