Linking the structure and thermal stability of β-galactoside-binding protein galectin-1 to ligand binding and dimerization equilibria

Biochemistry

Volumn 49, Issue 35, 2010, Pages 7652-7658

  Di Lella, Santiago ^a   Martí, Marcelo A ^a   Croci, Diego O ^b   Guardia, Carlos M A ^a   Díaz Ricci, Juan C ^c   Rabinovich, Gabriel A ^a,b   Caramelo, Julio J ^a,d   Estrin, Darío A ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

^d FUNDACIÓN INSTITUTO LELOIR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL SYSTEMS; DICHROISM; DIMERIZATION; LIGANDS; MOLECULAR DYNAMICS; PROTEINS; SUGARS; THERMODYNAMIC STABILITY;

BINDING PROTEINS; BIOLOGICAL FUNCTIONS; CIRCULAR DICHROISM; CONFORMATIONAL ENTROPY; DIFFERENT ORDER; DISACCHARIDE LACTOSE; EXPERIMENTAL EVIDENCE; GALECTIN-1; GLYCANS; INTERNAL ENERGIES; LIGAND BINDING; MOLECULAR DYNAMICS SIMULATIONS; PHYSICOCHEMICAL PROPERTY; SOLVATION FREE ENERGIES; STRUCTURAL CHANGE; THERAPEUTIC APPLICATION; THERMAL DENATURATIONS; THERMAL STABILITY;

BINDING ENERGY;

BETA GALACTOSIDE; CARBOHYDRATE BINDING PROTEIN; DISACCHARIDE; GALECTIN 1; GLYCAN; LACTOSE; LECTIN; RECOMBINANT PROTEIN; BETA-GALACTOSIDE; GALACTOSIDE; LIGAND;

ARTICLE; BACTERIAL CELL; CIRCULAR DICHROISM; DIMERIZATION; ENERGY; ENTROPY; ESCHERICHIA COLI; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN STRUCTURE; SPECTROSCOPY; STRUCTURE ANALYSIS; THERMODYNAMICS; THERMOSTABILITY; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN FOLDING;

BINDING SITES; DIMERIZATION; GALACTOSIDES; GALECTIN 1; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN FOLDING; THERMODYNAMICS;

EID: 77956165265     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100356g     Document Type: Article

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