메뉴 건너뛰기




Volumn 136, Issue 10, 2010, Pages 1617-1626

Loss of SOCS3 expression is associated with an increased risk of recurrent disease in breast carcinoma

Author keywords

Breast carcinoma; Prognosis; Signal transducers and activators of transcription 3; Suppressor of cytokine signaling 3

Indexed keywords

STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 77956060906     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0819-6     Document Type: Article
Times cited : (31)

References (33)
  • 2
    • 62449154733 scopus 로고    scopus 로고
    • SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL
    • 10.1002/ijc.24172 10.1002/ijc.24172 1:CAS:528:DC%2BD1MXjslSmsrs%3D 19115200
    • JL Barclay ST Anderson MJ Waters JD Curlewis 2009 SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL Int J Cancer 124 8 1756 1766 10.1002/ijc.24172 10.1002/ijc.24172 1:CAS:528:DC%2BD1MXjslSmsrs%3D 19115200
    • (2009) Int J Cancer , vol.124 , Issue.8 , pp. 1756-1766
    • Barclay, J.L.1    Anderson, S.T.2    Waters, M.J.3    Curlewis, J.D.4
  • 3
    • 0035912763 scopus 로고    scopus 로고
    • Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
    • 10.1073/pnas.131568898 10.1073/pnas.131568898 1:CAS:528: DC%2BD3MXkslWmtbk%3D 11404481
    • T Bowman MA Broome D Sinibaldi W Wharton WJ Pledger JM Sedivy R Irby T Yeatman SA Courtneidge R Jove 2001 Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis Proc Natl Acad Sci USA 98 13 7319 7324 10.1073/pnas.131568898 10.1073/pnas.131568898 1:CAS:528: DC%2BD3MXkslWmtbk%3D 11404481
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.13 , pp. 7319-7324
    • Bowman, T.1    Broome, M.A.2    Sinibaldi, D.3    Wharton, W.4    Pledger, W.J.5    Sedivy, J.M.6    Irby, R.7    Yeatman, T.8    Courtneidge, S.A.9    Jove, R.10
  • 4
    • 66349113501 scopus 로고    scopus 로고
    • SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases
    • 10.3324/haematol.2008.002352 10.3324/haematol.2008.002352 1:CAS:528:DC%2BD1MXpsFegtL4%3D 19229050
    • J Elliott Y Suessmuth LM Scott K Nahlik MF McMullin SN Constantinescu AR Green JA Johnston 2009 SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases Haematologica 94 4 576 580 10.3324/haematol.2008.002352 10.3324/haematol.2008. 002352 1:CAS:528:DC%2BD1MXpsFegtL4%3D 19229050
    • (2009) Haematologica , vol.94 , Issue.4 , pp. 576-580
    • Elliott, J.1    Suessmuth, Y.2    Scott, L.M.3    Nahlik, K.4    McMullin, M.F.5    Constantinescu, S.N.6    Green, A.R.7    Johnston, J.A.8
  • 5
    • 68049131461 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 sensitizes anaplastic thyroid cancer to standard chemotherapy
    • 10.1158/0008-5472.CAN-09-0994 10.1158/0008-5472.CAN-09-0994 1:CAS:528:DC%2BD1MXpt1CgtLg%3D 19638576
    • MG Francipane V Eterno V Spina M Bini G Scerrino G Buscemi G Gulotta M Todaro F Dieli R De Maria G Stassi 2009 Suppressor of cytokine signaling 3 sensitizes anaplastic thyroid cancer to standard chemotherapy Cancer Res 69 15 6141 6148 10.1158/0008-5472.CAN-09-0994 10.1158/0008-5472.CAN-09-0994 1:CAS:528:DC%2BD1MXpt1CgtLg%3D 19638576
    • (2009) Cancer Res , vol.69 , Issue.15 , pp. 6141-6148
    • Francipane, M.G.1    Eterno, V.2    Spina, V.3    Bini, M.4    Scerrino, G.5    Buscemi, G.6    Gulotta, G.7    Todaro, M.8    Dieli, F.9    De Maria, R.10    Stassi, G.11
  • 6
    • 0344440953 scopus 로고    scopus 로고
    • Regulation of cytokine signaling by SOCS family molecules
    • 10.1016/j.it.2003.10.008 10.1016/j.it.2003.10.008 1:CAS:528: DC%2BD3sXptlyhsr8%3D 14644140
    • M Fujimoto T Naka 2003 Regulation of cytokine signaling by SOCS family molecules Trends Immunol 24 12 659 666 10.1016/j.it.2003.10.008 10.1016/j.it.2003.10.008 1:CAS:528:DC%2BD3sXptlyhsr8%3D 14644140
    • (2003) Trends Immunol , vol.24 , Issue.12 , pp. 659-666
    • Fujimoto, M.1    Naka, T.2
  • 7
    • 0031443156 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
    • 1:CAS:528:DyaK2sXotVWlt7s%3D 9419415
    • R Garcia CL Yu A Hudnall R Catlett KL Nelson T Smithgall DJ Fujita SP Ethier R Jove 1997 Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells Cell Growth Differ 8 12 1267 1276 1:CAS:528:DyaK2sXotVWlt7s%3D 9419415
    • (1997) Cell Growth Differ , vol.8 , Issue.12 , pp. 1267-1276
    • Garcia, R.1    Yu, C.L.2    Hudnall, A.3    Catlett, R.4    Nelson, K.L.5    Smithgall, T.6    Fujita, D.J.7    Ethier, S.P.8    Jove, R.9
  • 8
    • 0035799531 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
    • 10.1038/sj.onc.1204349 10.1038/sj.onc.1204349 1:CAS:528: DC%2BD3MXjvFGmt7k%3D 11420660
    • R Garcia TL Bowman G Niu H Yu S Minton CA Muro-Cacho CE Cox R Falcone R Fairclough S Parsons A Laudano A Gazit A Levitzki A Kraker R Jove 2001 Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells Oncogene 20 20 2499 2513 10.1038/sj.onc.1204349 10.1038/sj.onc.1204349 1:CAS:528: DC%2BD3MXjvFGmt7k%3D 11420660
    • (2001) Oncogene , vol.20 , Issue.20 , pp. 2499-2513
    • Garcia, R.1    Bowman, T.L.2    Niu, G.3    Yu, H.4    Minton, S.5    Muro-Cacho, C.A.6    Cox, C.E.7    Falcone, R.8    Fairclough, R.9    Parsons, S.10    Laudano, A.11    Gazit, A.12    Levitzki, A.13    Kraker, A.14    Jove, R.15
  • 9
    • 0345492424 scopus 로고    scopus 로고
    • SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer
    • 10.1073/pnas.2232790100 10.1073/pnas.2232790100 1:CAS:528: DC%2BD3sXpsFGitLk%3D 14617776
    • B He L You K Uematsu K Zang Z Xu AY Lee JF Costello F McCormick DM Jablons 2003 SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer Proc Natl Acad Sci USA 100 24 14133 14138 10.1073/pnas.2232790100 10.1073/pnas.2232790100 1:CAS:528:DC%2BD3sXpsFGitLk%3D 14617776
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.24 , pp. 14133-14138
    • He, B.1    You, L.2    Uematsu, K.3    Zang, K.4    Xu, Z.5    Lee, A.Y.6    Costello, J.F.7    McCormick, F.8    Jablons, D.M.9
  • 10
    • 0032827081 scopus 로고    scopus 로고
    • Negative regulators of cytokine signal transduction
    • 10.1007/s000180050396 10.1007/s000180050396 1:CAS:528:DyaK1MXmtF2msLY%3D 10526574
    • DJ Hilton 1999 Negative regulators of cytokine signal transduction Cell Mol Life Sci 55 12 1568 1577 10.1007/s000180050396 10.1007/s000180050396 1:CAS:528:DyaK1MXmtF2msLY%3D 10526574
    • (1999) Cell Mol Life Sci , vol.55 , Issue.12 , pp. 1568-1577
    • Hilton, D.J.1
  • 11
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • 10.1038/sj.onc.1203551 10.1038/sj.onc.1203551 1:CAS:528: DC%2BD3cXktVGhsbY%3D 10851053
    • T Hirano K Ishihara M Hibi 2000 Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors Oncogene 19 21 2548 2556 10.1038/sj.onc.1203551 10.1038/sj.onc.1203551 1:CAS:528:DC%2BD3cXktVGhsbY%3D 10851053
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 12
    • 33745183825 scopus 로고    scopus 로고
    • STAT3-mediated constitutive expression of SOCS3 in an undifferentiated rat trophoblast-like cell line
    • 10.1016/j.placenta.2005.10.003 10.1016/j.placenta.2005.10.003 1:CAS:528:DC%2BD28XlvF2lsLc%3D 16300827
    • A Isobe T Takeda M Sakata T Yamamoto R Minekawa M Hayashi CJ Auernhammer K Tasaka Y Murata 2006 STAT3-mediated constitutive expression of SOCS3 in an undifferentiated rat trophoblast-like cell line Placenta 27 8 912 918 10.1016/j.placenta.2005.10.003 10.1016/j.placenta.2005.10.003 1:CAS:528:DC%2BD28XlvF2lsLc%3D 16300827
    • (2006) Placenta , vol.27 , Issue.8 , pp. 912-918
    • Isobe, A.1    Takeda, T.2    Sakata, M.3    Yamamoto, T.4    Minekawa, R.5    Hayashi, M.6    Auernhammer, C.J.7    Tasaka, K.8    Murata, Y.9
  • 13
    • 33846200831 scopus 로고    scopus 로고
    • Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing
    • 10.1053/j.gastro.2006.10.037 10.1053/j.gastro.2006.10.037 1:CAS:528:DC%2BD2sXit1aqt74%3D 17241887
    • H Isomoto JL Mott S Kobayashi NW Werneburg SF Bronk S Haan GJ Gores 2007 Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing Gastroenterology 132 1 384 396 10.1053/j.gastro.2006.10.037 10.1053/j.gastro.2006.10.037 1:CAS:528:DC%2BD2sXit1aqt74%3D 17241887
    • (2007) Gastroenterology , vol.132 , Issue.1 , pp. 384-396
    • Isomoto, H.1    Mott, J.L.2    Kobayashi, S.3    Werneburg, N.W.4    Bronk, S.F.5    Haan, S.6    Gores, G.J.7
  • 14
    • 38149083478 scopus 로고    scopus 로고
    • Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
    • 10.1074/jbc.M708568200 10.1074/jbc.M708568200 1:CAS:528: DC%2BD1cXhsFejsg%3D%3D 17993646
    • JH Kim JE Kim HY Liu W Cao J Chen 2008 Regulation of interleukin-6- induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway J Biol Chem 283 2 708 715 10.1074/jbc.M708568200 10.1074/jbc.M708568200 1:CAS:528:DC%2BD1cXhsFejsg%3D%3D 17993646
    • (2008) J Biol Chem , vol.283 , Issue.2 , pp. 708-715
    • Kim, J.H.1    Kim, J.E.2    Liu, H.Y.3    Cao, W.4    Chen, J.5
  • 15
    • 38449117957 scopus 로고    scopus 로고
    • Positive and negative roles of IL-6, STAT3, and SOCS3 in inflammatory arthritis
    • 10.1007/978-0-387-72009-8 10.1007/978-0-387-72009-8-15 17966396
    • I Kinjyo M Ohishi T Shouda T Kobayashi A Yoshimura 2007 Positive and negative roles of IL-6, STAT3, and SOCS3 in inflammatory arthritis Adv Exp Med Biol 602 113 124 10.1007/978-0-387-72009-8 10.1007/978-0-387-72009-8-15 17966396
    • (2007) Adv Exp Med Biol , vol.602 , pp. 113-124
    • Kinjyo, I.1    Ohishi, M.2    Shouda, T.3    Kobayashi, T.4    Yoshimura, A.5
  • 16
    • 33748343624 scopus 로고    scopus 로고
    • Overexpression of SOCS3 is associated with decreased survival in a cohort of patients with de novo follicular lymphoma
    • 10.1111/j.1365-2141.2006.06248.x 10.1111/j.1365-2141.2006.06248.x 16939500
    • R Krishnadasan C Bifulco J Kim S Rodov AW Zieske GJ Vanasse 2006 Overexpression of SOCS3 is associated with decreased survival in a cohort of patients with de novo follicular lymphoma Br J Haematol 135 1 72 75 10.1111/j.1365-2141.2006.06248.x 10.1111/j.1365-2141.2006.06248.x 16939500
    • (2006) Br J Haematol , vol.135 , Issue.1 , pp. 72-75
    • Krishnadasan, R.1    Bifulco, C.2    Kim, J.3    Rodov, S.4    Zieske, A.W.5    Vanasse, G.J.6
  • 17
    • 33845771270 scopus 로고    scopus 로고
    • Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3
    • 10.1158/1078-0432.CCR-06-0484 10.1158/1078-0432.CCR-06-0484 1:CAS:528:DC%2BD28Xht1Kns7bP 17145839
    • WC Li SL Ye RX Sun YK Liu ZY Tang Y Kim JG Karras H Zhang 2006 Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3 Clin Cancer Res 12 23 7140 7148 10.1158/1078-0432.CCR-06-0484 10.1158/1078-0432.CCR-06-0484 1:CAS:528:DC%2BD28Xht1Kns7bP 17145839
    • (2006) Clin Cancer Res , vol.12 , Issue.23 , pp. 7140-7148
    • Li, W.C.1    Ye, S.L.2    Sun, R.X.3    Liu, Y.K.4    Tang, Z.Y.5    Kim, Y.6    Karras, J.G.7    Zhang, H.8
  • 18
    • 57349117925 scopus 로고    scopus 로고
    • Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme
    • 10.1002/ijc.23805 10.1002/ijc.23805 1:CAS:528:DC%2BD1cXhsVKgt7%2FJ 18770864
    • M Martini R Pallini G Luongo T Cenci C Lucantoni LM Larocca 2008 Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme Int J Cancer 123 12 2955 2960 10.1002/ijc.23805 10.1002/ijc.23805 1:CAS:528:DC%2BD1cXhsVKgt7%2FJ 18770864
    • (2008) Int J Cancer , vol.123 , Issue.12 , pp. 2955-2960
    • Martini, M.1    Pallini, R.2    Luongo, G.3    Cenci, T.4    Lucantoni, C.5    Larocca, L.M.6
  • 20
    • 38749118957 scopus 로고    scopus 로고
    • Decreased expression of SOCS-3 mRNA in breast cancer with lymph node metastasis
    • 1:CAS:528:DC%2BD1cXhtFKru74%3D 18097573
    • T Nakagawa S Iida T Osanai H Uetake T Aruga Y Toriya Y Takagi H Kawachi K Sugihara 2008 Decreased expression of SOCS-3 mRNA in breast cancer with lymph node metastasis Oncol Rep 19 1 33 39 1:CAS:528:DC%2BD1cXhtFKru74%3D 18097573
    • (2008) Oncol Rep , vol.19 , Issue.1 , pp. 33-39
    • Nakagawa, T.1    Iida, S.2    Osanai, T.3    Uetake, H.4    Aruga, T.5    Toriya, Y.6    Takagi, Y.7    Kawachi, H.8    Sugihara, K.9
  • 22
    • 33745750797 scopus 로고    scopus 로고
    • Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepato-carcinogenesis
    • 10.1053/j.gastro.2006.04.025 10.1053/j.gastro.2006.04.025 1:CAS:528:DC%2BD28XnvF2gsb0%3D 16831601
    • H Ogata T Kobayashi T Chinen H Takaki T Sanada Y Minoda K Koga G Takaesu Y Maehara M Iida A Yoshimura 2006 Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepato-carcinogenesis Gastroenterology 131 1 179 193 10.1053/j.gastro.2006.04.025 10.1053/j.gastro. 2006.04.025 1:CAS:528:DC%2BD28XnvF2gsb0%3D 16831601
    • (2006) Gastroenterology , vol.131 , Issue.1 , pp. 179-193
    • Ogata, H.1    Kobayashi, T.2    Chinen, T.3    Takaki, H.4    Sanada, T.5    Minoda, Y.6    Koga, K.7    Takaesu, G.8    Maehara, Y.9    Iida, M.10    Yoshimura, A.11
  • 23
    • 62749172432 scopus 로고    scopus 로고
    • The evolution of lymph node assessment in breast cancer
    • 10.1002/jso.21201 10.1002/jso.21201 19021226
    • ML Quan D McCready 2009 The evolution of lymph node assessment in breast cancer J Surg Oncol 99 4 194 198 10.1002/jso.21201 10.1002/jso.21201 19021226
    • (2009) J Surg Oncol , vol.99 , Issue.4 , pp. 194-198
    • Quan, M.L.1    McCready, D.2
  • 24
    • 38749084203 scopus 로고    scopus 로고
    • Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
    • 10.1084/jem.20070820 10.1084/jem.20070820 1:CAS:528:DC%2BD1cXht1ykt7Y%3D 18158318
    • KJ Riehle JS Campbell RS McMahan MM Johnson RP Beyer TK Bammler N Fausto 2008 Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3 J Exp Med 205 1 91 103 10.1084/jem.20070820 10.1084/jem.20070820 1:CAS:528:DC%2BD1cXht1ykt7Y%3D 18158318
    • (2008) J Exp Med , vol.205 , Issue.1 , pp. 91-103
    • Riehle, K.J.1    Campbell, J.S.2    McMahan, R.S.3    Johnson, M.M.4    Beyer, R.P.5    Bammler, T.K.6    Fausto, N.7
  • 25
    • 0035979275 scopus 로고    scopus 로고
    • Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
    • 10.1073/pnas.161271798 10.1073/pnas.161271798 1:CAS:528: DC%2BD3MXlvFSrsLg%3D 11481489
    • AW Roberts L Robb S Rakar L Hartley L Cluse NA Nicola D Metcalf DJ Hilton WS Alexander 2001 Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3 Proc Natl Acad Sci USA 98 16 9324 9329 10.1073/pnas.161271798 10.1073/pnas.161271798 1:CAS:528:DC%2BD3MXlvFSrsLg%3D 11481489
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.16 , pp. 9324-9329
    • Roberts, A.W.1    Robb, L.2    Rakar, S.3    Hartley, L.4    Cluse, L.5    Nicola, N.A.6    Metcalf, D.7    Hilton, D.J.8    Alexander, W.S.9
  • 26
    • 53349153184 scopus 로고    scopus 로고
    • Prognostic value of signal transducers and activators of transcription 3 in breast cancer
    • 10.1158/1055-9965.EPI-08-0089 10.1158/1055-9965.EPI-08-0089 1:CAS:528:DC%2BD1cXhtVKmtLjM
    • SM Sheen-Chen CC Huang RP Tang FF Chou HL Eng 2008 Prognostic value of signal transducers and activators of transcription 3 in breast cancer Cancer Epidemiol Biomark Prev 17 9 2286 2290 10.1158/1055-9965.EPI-08-0089 10.1158/1055-9965.EPI-08-0089 1:CAS:528:DC%2BD1cXhtVKmtLjM
    • (2008) Cancer Epidemiol Biomark Prev , vol.17 , Issue.9 , pp. 2286-2290
    • Sheen-Chen, S.M.1    Huang, C.C.2    Tang, R.P.3    Chou, F.F.4    Eng, H.L.5
  • 27
    • 0037415694 scopus 로고    scopus 로고
    • SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
    • 10.1093/emboj/cdg057 10.1093/emboj/cdg057 1:CAS:528:DC%2BD3sXitlKlu70%3D 12554639
    • Y Takahashi N Carpino JC Cross M Torres E Parganas JN Ihle 2003 SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation EMBO J 22 3 372 384 10.1093/emboj/cdg057 10.1093/emboj/cdg057 1:CAS:528:DC%2BD3sXitlKlu70%3D 12554639
    • (2003) EMBO J , vol.22 , Issue.3 , pp. 372-384
    • Takahashi, Y.1    Carpino, N.2    Cross, J.C.3    Torres, M.4    Parganas, E.5    Ihle, J.N.6
  • 28
    • 46349097234 scopus 로고    scopus 로고
    • Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway
    • 10.1210/me.2008-0058 10.1210/me.2008-0058 1:CAS:528:DC%2BD1cXot1ehurc%3D 18451094
    • Y Takahashi M Takahashi N Carpino ST Jou JR Chao S Tanaka Y Shigeyoshi E Parganas JN Ihle 2008 Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway Mol Endocrinol 22 7 1673 1681 10.1210/me.2008-0058 10.1210/me.2008-0058 1:CAS:528: DC%2BD1cXot1ehurc%3D 18451094
    • (2008) Mol Endocrinol , vol.22 , Issue.7 , pp. 1673-1681
    • Takahashi, Y.1    Takahashi, M.2    Carpino, N.3    Jou, S.T.4    Chao, J.R.5    Tanaka, S.6    Shigeyoshi, Y.7    Parganas, E.8    Ihle, J.N.9
  • 29
    • 33947726956 scopus 로고    scopus 로고
    • Methylation status of the SOCS3 gene in human malignant melanomas
    • 1:CAS:528:DC%2BD2sXjtFGgtbo%3D 17273770
    • T Tokita C Maesawa T Kimura K Kotani K Takahashi T Akasaka T Masuda 2007 Methylation status of the SOCS3 gene in human malignant melanomas Int J Oncol 30 3 689 694 1:CAS:528:DC%2BD2sXjtFGgtbo%3D 17273770
    • (2007) Int J Oncol , vol.30 , Issue.3 , pp. 689-694
    • Tokita, T.1    Maesawa, C.2    Kimura, T.3    Kotani, K.4    Takahashi, K.5    Akasaka, T.6    Masuda, T.7
  • 30
    • 27144540201 scopus 로고    scopus 로고
    • SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition
    • 10.1038/sj.onc.1208818 10.1038/sj.onc.1208818 1:CAS:528: DC%2BD2MXhtVOjsrzN 16007169
    • A Weber UR Hengge W Bardenheuer I Tischoff F Sommerer A Markwarth A Dietz C Wittekind A Tannapfel 2005 SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition Oncogene 24 44 6699 6708 10.1038/sj.onc.1208818 10.1038/sj.onc.1208818 1:CAS:528:DC%2BD2MXhtVOjsrzN 16007169
    • (2005) Oncogene , vol.24 , Issue.44 , pp. 6699-6708
    • Weber, A.1    Hengge, U.R.2    Bardenheuer, W.3    Tischoff, I.4    Sommerer, F.5    Markwarth, A.6    Dietz, A.7    Wittekind, C.8    Tannapfel, A.9
  • 31
    • 34548576919 scopus 로고    scopus 로고
    • Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides
    • 1:CAS:528:DC%2BD2sXot1Ojsr8%3D 17549413
    • P Weerasinghe GE Garcia Q Zhu P Yuan L Feng L Mao N Jing 2007 Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides Int J Oncol 31 1 129 136 1:CAS:528: DC%2BD2sXot1Ojsr8%3D 17549413
    • (2007) Int J Oncol , vol.31 , Issue.1 , pp. 129-136
    • Weerasinghe, P.1    Garcia, G.E.2    Zhu, Q.3    Yuan, P.4    Feng, L.5    Mao, L.6    Jing, N.7
  • 32
    • 50449106127 scopus 로고    scopus 로고
    • SOCS-3 is associated with vascular invasion and overall survival in hepatocellular carcinoma
    • 10.1080/00313020802320432 10.1080/00313020802320432 1:CAS:528: DC%2BD1cXhtVGnsb%2FF 18752121
    • SF Yang YT Yeh SN Wang SC Hung WT Chen CH Huang CY Chai 2008 SOCS-3 is associated with vascular invasion and overall survival in hepatocellular carcinoma Pathology 40 6 558 563 10.1080/00313020802320432 10.1080/ 00313020802320432 1:CAS:528:DC%2BD1cXhtVGnsb%2FF 18752121
    • (2008) Pathology , vol.40 , Issue.6 , pp. 558-563
    • Yang, S.F.1    Yeh, Y.T.2    Wang, S.N.3    Hung, S.C.4    Chen, W.T.5    Huang, C.H.6    Chai, C.Y.7
  • 33
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer-new molecular target come of age
    • 10.1038/nrc1275 10.1038/nrc1275 1:CAS:528:DC%2BD2cXhtlaqtb0%3D 14964307
    • H Yu R Jove 2004 The STATs of cancer-new molecular target come of age Nat Rev Cancer 4 2 97 105 10.1038/nrc1275 10.1038/nrc1275 1:CAS:528: DC%2BD2cXhtlaqtb0%3D 14964307
    • (2004) Nat Rev Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.