Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response

Investigational New Drugs

Volumn 28, Issue 5, 2010, Pages 703-713

  Kaur, Gurpreet ^a   Athar, Mohammad ^a,b   Alam, M Sarwar ^a  

^a HAMDARD UNIVERSITY   (India)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Ferric nitrilotriacetate; NF B; Oxidative stress; Silymarin; Tumor promotion

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE; ANTIOXIDANT; CYCLOOXYGENASE 2; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; METALLOTHIONEIN; NITRIC OXIDE SYNTHASE; NITRILOTRIACETATE IRON; ORNITHINE DECARBOXYLASE; SILYMARIN; TUMOR NECROSIS FACTOR ALPHA; 4-HYDROXY-2-NONENAL; AUTACOID; CYTOKINE; DNA; FERRIC ION; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRILOTRIACETIC ACID; PROTECTIVE AGENT; PTGS2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA SYNTHESIS; FEMALE; GENE EXPRESSION; INFLAMMATION; KIDNEY CANCER; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SILYBUM MARIANUM; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; BLOOD; COMPLICATION; DRUG DETOXIFICATION; DRUG EFFECTS; ENZYMOLOGY; KIDNEY; KIDNEY NEOPLASMS; LIPID PEROXIDATION; METABOLISM; PATHOLOGY; TREATMENT OUTCOME;

ALDEHYDES; ANIMALS; ANTIOXIDANTS; CYCLOOXYGENASE 2; CYTOKINES; DIETARY SUPPLEMENTS; DNA, NEOPLASM; FEMALE; FERRIC COMPOUNDS; INFLAMMATION; INFLAMMATION MEDIATORS; KIDNEY; KIDNEY NEOPLASMS; LIPID PEROXIDATION; METABOLIC DETOXICATION, PHASE II; METALLOTHIONEIN; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NITRILOTRIACETIC ACID; ORNITHINE DECARBOXYLASE; PROTECTIVE AGENTS; SILYMARIN; TREATMENT OUTCOME;

EID: 77956058430     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-009-9289-6     Document Type: Article

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