Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population

Heart and Vessels

Volumn 25, Issue 5, 2010, Pages 368-373

  Zhang, Kai ^a,b   Wang, Yuan Yuan ^a,b   Liu, Qi Ji ^c   Wang, Hui ^c   Liu, Fang Fang ^a,b   Ma, Zhi Yong ^a,b   Gong, Yao Qin ^c   Li, Li ^a,b  

^a Qilu Hospital of Shandong University   (China)

^b SHANDONG UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Arachidonate 15 lipoxygenase; Chinese Han population; Coronary artery disease; Single nucleotide polymorphism

Indexed keywords

ARACHIDONATE 12 15 LIPOXYGENASE; CHOLESTEROL; DIOXYGENASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; AGE; ALLELE; ARTICLE; BODY MASS; CASE CONTROL STUDY; CHINESE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLIC BLOOD PRESSURE; FEMALE; GENDER; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SYSTOLIC BLOOD PRESSURE;

AGED; ARACHIDONATE 15-LIPOXYGENASE; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHINA; CORONARY ARTERY DISEASE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; RISK FACTORS;

EID: 77956034572     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00380-009-1223-5     Document Type: Article

References (33)

1. R. Ross 1999 Atherosclerosis: an inflammatory disease N Engl J Med 340 115 126 10.1056/NEJM199901143400207 9887164 1:STN:280:DyaK1M%2FptFSqtQ%3D%3D
2. S. Ylä-Herttuala W. Palinski M.E. Rosenfeld S. Parthasarathy T.E. Carew S. Butler J.L. Witztum D. Steinberg 1989 Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man J Clin Invest 84 1086 1095 10.1172/JCI114271 2794046
3. W. Palinski M.E. Rosenfeld S. Ylä-Herttuala G.C. Gurtner S.S. Socher S.W. Butler S. Parthasarathy T.E. Carew D. Steinberg J.L. Witztum 1989 Low density lipoprotein undergoes oxidative modification in vivo Proc Natl Acad Sci USA 86 1372 1376 10.1073/pnas.86.4.1372 2465552 1:CAS:528:DyaL1MXhvV2rtb4%3D
4. G.M. Chisolm D. Steinberg 2000 The oxidative modification hypothesis of atherogenesis: an overview Free Radic Biol Med 28 1815 1826 10.1016/S0891- 5849(00)00344-0 10946223 1:CAS:528:DC%2BD3cXls1GhsrY%3D
5. D. Steinberg 2002 Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime Nat Med 8 1211 1217 10.1038/nm1102-1211 12411947 1:CAS:528:DC%2BD38XotlWmurc%3D
6. H. Kuhn B.J. Thiele 1999 The diversity of the lipoxygenase family. Many sequence data but little information on biological significance FEBS Lett 449 7 11 10.1016/S0014-5793(99)00396-8 10225417 1:CAS:528:DyaK1MXis1arsbs%3D
7. E.L. da Silva D.S. Abdalla J. Terao 2000 Inhibitory effect of flavonoids on low-density lipoprotein peroxidation catalyzed by mammalian 15-lipoxygenase IUBMB Life 49 289 295 10.1080/15216540050033159 10995031
8. M.K. Cathcart V.A. Folcik 2000 Lipoxygenases and atherosclerosis: protection versus pathogenesis Free Radic Biol Med 28 1726 1734 10.1016/S0891-5849(00)00230-6 10946214 1:CAS:528:DC%2BD3cXls1Giu7c%3D
9. T. Cyrus D. Praticò L. Zhao J.L. Witztum D.J. Rader J. Rokach G.A. FitzGerald C.D. Funk 2001 Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice Circulation 103 2277 2282 11342477 1:CAS:528:DC%2BD3MXkt1Gnt7Y%3D
10. J. George A. Afek A. Shaish H. Levkovitz N. Bloom T. Cyrus L. Zhao C.D. Funk E. Sigal D. Harats 2001 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice Circulation 104 1646 1650 10.1161/hc3901.095772 11581143 1:CAS:528:DC%2BD3MXotVeht7Y%3D
11. T. Hiltunen J. Luoma T. Nikkari S. Ylä-Herttuala 1995 Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions Circulation 92 3297 3303 7586317 1:CAS:528:DyaK28XhslOrtw%3D%3D
12. S. Ylä-Herttuala M.E. Rosenfeld S. Parthasarathy C.K. Glass E. Sigal J.L. Witztum D. Steinberg 1990 Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions Proc Natl Acad Sci USA 87 6959 6963 10.1073/pnas.87.18.6959 1698286
13. H. Kühn D. Heydeck I. Hugou C. Gniwotta 1997 In vivo action of 15-lipoxygenase in early stages of human atherogenesis J Clin Invest 99 888 893 10.1172/JCI119253 9062346
14. K.B. Reilly S. Srinivasan M.E. Hatley M.K. Patricia J. Lannigan D.T. Bolick G. Vandenhoff H. Pei R. Natarajan J.L. Nadler C.C. Hedrick 2004 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo J Biol Chem 279 9440 9450 10.1074/jbc.M303857200 14676201 1:CAS:528:DC%2BD2cXhs1Omtrs%3D
15. D.T. Bolick A.W. Orr A. Whetzel S. Srinivasan M.E. Hatley M.A. Schwartz C.C. Hedrick 2005 12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factorkappaB Arterioscler Thromb Vasc Biol 25 2301 2307 10.1161/01.ATV.0000186181.19909.a6 16166569 1:CAS:528:DC%2BD2MXhtFCisbfL
16. J. Wölle K.A. Welch L.J. Devall J.A. Cornicelli U. Saxena 1996 Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression Biochem Biophys Res Commun 220 310 314 10.1006/bbrc.1996.0402 8645302
17. R. Natarajan H. Pei J.L. Gu J.M. Sarma J. Nadler 1999 Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury Cardiovasc Res 41 489 499 10.1016/S0008-6363(98)00312-5 10341849 1:CAS:528: DyaK1MXht12qsrg%3D
18. J. Nakao T. Ooyama H. Ito W.C. Chang S. Murota 1982 Comparative effect of lipoxygenase products of arachidonic acid on rat aortic smooth muscle cell migration Atherosclerosis 44 339 342 10.1016/0021-9150(82)90008-9 6816252 1:CAS:528:DyaL38XlvFKgurs%3D
19. R. Natarajan J. Rosdahl N. Gonzales W. Bai 1997 Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells Hypertension 30 873 879 9336387 1:CAS:528:DyaK2sXntFSis7Y%3D
20. A.M. Taylor R. Hanchett R. Natarajan C.C. Hedrick S. Forrest J.L. Nadler C.A. McNamara 2005 The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growth Arterioscler Thromb Vasc Biol 25 2069 2074 10.1161/01.ATV.0000178992.40088.f2 16037566 1:CAS:528: DC%2BD2MXhtVCltrvE
21. J. Shen H. Kuhn A. Petho-Schramm L. Chan 1995 Transgenic rabbits with the integrated human 15-lipoxygenase gene driven by a lysozyme promoter: macrophage-specific expression and variable positional specificity of the transgenic enzyme FASEB J 9 1623 1631 8529842 1:CAS:528:DyaK28XhsVCkuw%3D%3D
22. J. Shen E. Herderick J.F. Cornhill E. Zsigmond H.S. Kim H. Kühn N.V. Guevara L. Chan 1996 Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development J Clin Invest 98 2201 2208 10.1172/JCI119029 8941635 1:CAS:528:DyaK28XntVOhs7Y%3D
23. F. Trebus D. Heydeck I. Schimke C. Gerth H. Kuhn 2002 Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition Prostaglandins Leukotrienes Essent Fatty Acids 67 419 428 10.1054/plef.2002.0452 1:CAS:528:DC%2BD38XpsVOqsbg%3D
24. A.J. Merched K. Ko K.H. Gotlinger C.N. Serhan L. Chan 2008 Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators FASEB J 22 3595 3606 10.1096/fj.08-112201 18559988 1:CAS:528:DC%2BD1cXht1SqsrbL
25. P.M. Biselli A.R. Guerzoni M.F. de Godoy C. Pavarino-Bertelli E.M. Goloni-Bertollo 2008 Vascular endothelial growth factor genetic variability and coronary artery disease in Brazilian population Heart Vessels 23 371 375 10.1007/s00380-008-1057-6 19037583
26. I. Zak B. Sarecka J. Krauze 2008 Synergistic effects between 561A>C and 98G>T polymorphisms of E-selectin gene and hypercholesterolemia in determining the susceptibility to coronary artery disease Heart Vessels 23 257 263 10.1007/s00380-008-1040-2 18649056
27. T.L. Assimes J.W. Knowles J.R. Priest A. Basu A. Borchert K.A. Volcik M.L. Grove H.K. Tabor A. Southwick R. Tabibiazar S. Sidney E. Boerwinkle A.S. Go C. Iribarren M.A. Hlatky S.P. Fortmann R.M. Myers H. Kuhn N. Risch T. Quertermous 2008 A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease Atherosclerosis 198 136 144 10.1016/j.atherosclerosis.2007.09.003 17959182 1:CAS:528:DC%2BD1cXktFCmu7s%3D
28. J. Wittwer M. Bayer A. Mosandl J. Muntwyler M. Hersberger 2007 The c.-292C>T promoter polymorphism increases reticulocytetype 15-lipoxygenase-1 activity and could be athero-protective Clin Chem Lab Med 45 487 492 10.1515/CCLM.2007.103 17439326 1:CAS:528:DC%2BD2sXlsVWntL8%3D
29. P.A. McCaskie J.P. Beilby J. Hung C.M. Chapman B.M. McQuillan B.L. Powell P.L. Thompson L.J. Palmer 2008 15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intimamedia thickness Hum Genet 123 445 453 10.1007/s00439-008-0496-6 18392641 1:CAS:528:DC%2BD1cXmtVaisrw%3D
30. M. Hersberger M. Müller J. Marti-Jaun I.M. Heid S. Coassin T.F. Young V. Waechter C. Hengstenberg C. Meisinger A. Peters W. König S. Holmer H. Schunkert N. Klopp F. Kronenberg T. Illig 2009 No association of two functional polymorphisms in human ALOX15 with myocardial infarction Athrosclerosis 205 192 196 10.1016/j.atherosclerosis.2008.11.017 1:CAS:528:DC%2BD1MXnsFagt7w%3D
31. P. Puddu E. Cravero G.M. Puddu A. Muscari 2005 Genes and atherosclerosis: at the origin of the predisposition Int J Clin Pract 59 462 472 10.1111/j.1368-5031.2005.00439.x 15853866 1:STN:280:DC%2BD2M3itVGmsg%3D%3D
32. J. Wittwer J. Marti-Jaun M. Hersberger 2006 Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1 Hum Mutat 27 78 87 10.1002/humu.20273 16320347 1:CAS:528:DC%2BD28XotlOkuw%3D%3D
33. M.E. Marenberg N. Risch L.F. Berkman B. Floderus U. de Faire 1994 Genetic susceptibility to death from coronary heart disease in a study of twins N Engl J Med 330 1041 1046 10.1056/NEJM199404143301503 8127331 1:STN:280: DyaK2c7ntlaqtg%3D%3D