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Volumn 34, Issue 10, 2010, Pages 1366-1373

NFκB modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia

Author keywords

Childhood acute lymphoblastic leukaemia; Glucocorticoid resistance; NF B

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID INDUCED LEUCINE ZIPPER PROTEIN; GLUCOCORTICOID RECEPTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; RAF PROTEIN; RAS PROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; GLUCOCORTICOID; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; TRANSCRIPTION FACTOR; TSC22D3 PROTEIN, HUMAN;

EID: 77955981207     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.12.014     Document Type: Article
Times cited : (7)

References (41)
  • 2
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
    • Ray A., Prefontaine K.E. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci USA 1994, 91:752-756.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 3
    • 33846467093 scopus 로고    scopus 로고
    • Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids
    • Herr I., Gassler N., Friess H., Buchler M.W. Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids. Apoptosis 2007, 12:271-291.
    • (2007) Apoptosis , vol.12 , pp. 271-291
    • Herr, I.1    Gassler, N.2    Friess, H.3    Buchler, M.W.4
  • 4
    • 0023186011 scopus 로고
    • Corticosteroid-dependent reduction of leukocyte count in blood as a prognostic factor in acute lymphoblastic leukemia in childhood (therapy study ALL-BFM 83)
    • Riehm H., Reiter A., Schrappe M., Berthold F., Dopfer R., Gerein V., et al. Corticosteroid-dependent reduction of leukocyte count in blood as a prognostic factor in acute lymphoblastic leukemia in childhood (therapy study ALL-BFM 83). Klin Padiatr 1987, 199:151-160.
    • (1987) Klin Padiatr , vol.199 , pp. 151-160
    • Riehm, H.1    Reiter, A.2    Schrappe, M.3    Berthold, F.4    Dopfer, R.5    Gerein, V.6
  • 5
    • 0028152851 scopus 로고
    • Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86
    • Reiter A., Schrappe M., Ludwig W.D., Hiddemann W., Sauter S., Henze G., et al. Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86. Blood 1994, 84:3122-3133.
    • (1994) Blood , vol.84 , pp. 3122-3133
    • Reiter, A.1    Schrappe, M.2    Ludwig, W.D.3    Hiddemann, W.4    Sauter, S.5    Henze, G.6
  • 6
    • 0034517924 scopus 로고    scopus 로고
    • Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster
    • Schrappe M., Reiter A., Zimmermann M., Harbott J., Ludwig W.D., Henze G., et al. Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster. Leukemia 2000, 14:2205-2222.
    • (2000) Leukemia , vol.14 , pp. 2205-2222
    • Schrappe, M.1    Reiter, A.2    Zimmermann, M.3    Harbott, J.4    Ludwig, W.D.5    Henze, G.6
  • 7
    • 0028803598 scopus 로고
    • In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia
    • Klumper E., Pieters R., Veerman A., Huismans D., Loonen A., Hahlen K., et al. In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia. Blood 1995, 86:3861-3868.
    • (1995) Blood , vol.86 , pp. 3861-3868
    • Klumper, E.1    Pieters, R.2    Veerman, A.3    Huismans, D.4    Loonen, A.5    Hahlen, K.6
  • 8
    • 20444470738 scopus 로고    scopus 로고
    • Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia
    • Kaspers G.J., Wijnands J.J., Hartmann R., Huismans L., Loonen A.H., Stackelberg A., et al. Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia. Eur J Cancer 2005, 41:1300-1303.
    • (2005) Eur J Cancer , vol.41 , pp. 1300-1303
    • Kaspers, G.J.1    Wijnands, J.J.2    Hartmann, R.3    Huismans, L.4    Loonen, A.H.5    Stackelberg, A.6
  • 9
    • 0043172317 scopus 로고    scopus 로고
    • Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia
    • Kofler R., Schmidt S., Kofler A., Ausserlechner M.J. Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia. J Endocrinol 2003, 178:19-27.
    • (2003) J Endocrinol , vol.178 , pp. 19-27
    • Kofler, R.1    Schmidt, S.2    Kofler, A.3    Ausserlechner, M.J.4
  • 10
    • 0037355622 scopus 로고    scopus 로고
    • Glucocorticoid resistance in childhood leukaemia: mechanisms and modulation
    • Haarman E.G., Kaspers G.J., Veerman A.J. Glucocorticoid resistance in childhood leukaemia: mechanisms and modulation. Br J Haematol 2003, 120:919-929.
    • (2003) Br J Haematol , vol.120 , pp. 919-929
    • Haarman, E.G.1    Kaspers, G.J.2    Veerman, A.J.3
  • 11
    • 27544446055 scopus 로고    scopus 로고
    • Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course
    • Irving J.A., Minto L., Bailey S., Hall A.G. Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course. Cancer Res 2005, 65:9712-9718.
    • (2005) Cancer Res , vol.65 , pp. 9712-9718
    • Irving, J.A.1    Minto, L.2    Bailey, S.3    Hall, A.G.4
  • 12
    • 23844473613 scopus 로고    scopus 로고
    • Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia
    • Tissing W.J., Meijerink J.P., den Boer M.L., Brinkhof B., van Rossum E.F., van Wering E.R., et al. Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia. Clin Cancer Res 2005, 11:6050-6056.
    • (2005) Clin Cancer Res , vol.11 , pp. 6050-6056
    • Tissing, W.J.1    Meijerink, J.P.2    den Boer, M.L.3    Brinkhof, B.4    van Rossum, E.F.5    van Wering, E.R.6
  • 13
    • 33845655483 scopus 로고    scopus 로고
    • Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor
    • Schmidt S., Irving J.A., Minto L., Matheson E., Nicholson L., Ploner A., et al. Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor. FASEB J 2006, 20:2600-2602.
    • (2006) FASEB J , vol.20 , pp. 2600-2602
    • Schmidt, S.1    Irving, J.A.2    Minto, L.3    Matheson, E.4    Nicholson, L.5    Ploner, A.6
  • 14
    • 0037275722 scopus 로고    scopus 로고
    • Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia
    • Matheson E.C., Hall A.G. Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia. Carcinogenesis 2003, 24:31-38.
    • (2003) Carcinogenesis , vol.24 , pp. 31-38
    • Matheson, E.C.1    Hall, A.G.2
  • 15
    • 85047699977 scopus 로고    scopus 로고
    • Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays
    • Chauhan D., Auclair D., Robinson E.K., Hideshima T., Li G., Podar K., et al. Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays. Oncogene 2002, 21:1346-1358.
    • (2002) Oncogene , vol.21 , pp. 1346-1358
    • Chauhan, D.1    Auclair, D.2    Robinson, E.K.3    Hideshima, T.4    Li, G.5    Podar, K.6
  • 16
    • 39049170755 scopus 로고    scopus 로고
    • Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids
    • Miller A.L., Komak S., Webb M.S., Leiter E.H., Thompson E.B. Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids. Cancer Cell Int 2007, 7:18.
    • (2007) Cancer Cell Int , vol.7 , pp. 18
    • Miller, A.L.1    Komak, S.2    Webb, M.S.3    Leiter, E.H.4    Thompson, E.B.5
  • 17
    • 33644542448 scopus 로고    scopus 로고
    • Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia
    • Schmidt S., Rainer J., Riml S., Ploner C., Jesacher S., Achmuller C., et al. Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia. Blood 2006, 107:2061-2069.
    • (2006) Blood , vol.107 , pp. 2061-2069
    • Schmidt, S.1    Rainer, J.2    Riml, S.3    Ploner, C.4    Jesacher, S.5    Achmuller, C.6
  • 18
    • 0028909667 scopus 로고
    • Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids
    • Caldenhoven E., Liden J., Wissink S., Van de Stolpe A., Raaijmakers J., Koenderman L., et al. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol Endocrinol 1995, 9:401-412.
    • (1995) Mol Endocrinol , vol.9 , pp. 401-412
    • Caldenhoven, E.1    Liden, J.2    Wissink, S.3    Van de Stolpe, A.4    Raaijmakers, J.5    Koenderman, L.6
  • 19
    • 0035437169 scopus 로고    scopus 로고
    • Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB
    • Ayroldi E., Migliorati G., Bruscoli S., Marchetti C., Zollo O., Cannarile L., et al. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. Blood 2001, 98:743-753.
    • (2001) Blood , vol.98 , pp. 743-753
    • Ayroldi, E.1    Migliorati, G.2    Bruscoli, S.3    Marchetti, C.4    Zollo, O.5    Cannarile, L.6
  • 20
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins N.D. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007, 8:49-62.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 21
    • 33745980458 scopus 로고    scopus 로고
    • Competition between glucocorticoid receptor and NFkappaB for control of the human FasL promoter
    • Novac N., Baus D., Dostert A., Heinzel T. Competition between glucocorticoid receptor and NFkappaB for control of the human FasL promoter. FASEB J 2006, 20:1074-1081.
    • (2006) FASEB J , vol.20 , pp. 1074-1081
    • Novac, N.1    Baus, D.2    Dostert, A.3    Heinzel, T.4
  • 22
    • 0032491483 scopus 로고    scopus 로고
    • Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1
    • Sheppard K.A., Phelps K.M., Williams A.J., Thanos D., Glass C.K., Rosenfeld M.G., et al. Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem 1998, 273:29291-29294.
    • (1998) J Biol Chem , vol.273 , pp. 29291-29294
    • Sheppard, K.A.1    Phelps, K.M.2    Williams, A.J.3    Thanos, D.4    Glass, C.K.5    Rosenfeld, M.G.6
  • 23
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995, 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 24
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 25
    • 0034657307 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement
    • Petro J.B., Rahman S.M., Ballard D.W., Khan W.N. Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement. J Exp Med 2000, 191:1745-1754.
    • (2000) J Exp Med , vol.191 , pp. 1745-1754
    • Petro, J.B.1    Rahman, S.M.2    Ballard, D.W.3    Khan, W.N.4
  • 27
    • 0034092559 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells
    • Kordes U., Krappmann D., Heissmeyer V., Ludwig W.D., Scheidereit C. Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia 2000, 14:399-402.
    • (2000) Leukemia , vol.14 , pp. 399-402
    • Kordes, U.1    Krappmann, D.2    Heissmeyer, V.3    Ludwig, W.D.4    Scheidereit, C.5
  • 28
    • 0036785525 scopus 로고    scopus 로고
    • DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells
    • Zhou M., Gu L., Li F., Zhu Y., Woods W.G., Findley H.W. DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells. J Pharmacol Exp Ther 2002, 303:124-131.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 124-131
    • Zhou, M.1    Gu, L.2    Li, F.3    Zhu, Y.4    Woods, W.G.5    Findley, H.W.6
  • 29
    • 0028134964 scopus 로고
    • Isolation of nuclear extracts from fragile cells: a simplified procedure applied to thymocytes
    • Olnes M.I., Kurl R.N. Isolation of nuclear extracts from fragile cells: a simplified procedure applied to thymocytes. Biotechniques 1994, 17:828-829.
    • (1994) Biotechniques , vol.17 , pp. 828-829
    • Olnes, M.I.1    Kurl, R.N.2
  • 33
    • 34249290768 scopus 로고    scopus 로고
    • Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia
    • Bachmann P.S., Gorman R., Papa R.A., Bardell J.E., Ford J., Kees U.R., et al. Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia. Cancer Res 2007, 67:4482-4490.
    • (2007) Cancer Res , vol.67 , pp. 4482-4490
    • Bachmann, P.S.1    Gorman, R.2    Papa, R.A.3    Bardell, J.E.4    Ford, J.5    Kees, U.R.6
  • 34
    • 0036840376 scopus 로고    scopus 로고
    • Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1
    • Ayroldi E., Zollo O., Macchiarulo A., Di Marco B., Marchetti C., Riccardi C. Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1. Mol Cell Biol 2002, 22:7929-7941.
    • (2002) Mol Cell Biol , vol.22 , pp. 7929-7941
    • Ayroldi, E.1    Zollo, O.2    Macchiarulo, A.3    Di Marco, B.4    Marchetti, C.5    Riccardi, C.6
  • 35
    • 33749640683 scopus 로고    scopus 로고
    • Modification of glucocorticoid sensitivity by MAP kinase signaling pathways in glucocorticoid-induced T-cell apoptosis
    • Tanaka T., Okabe T., Gondo S., Fukuda M., Yamamoto M., Umemura T., et al. Modification of glucocorticoid sensitivity by MAP kinase signaling pathways in glucocorticoid-induced T-cell apoptosis. Exp Hematol 2006, 34:1542-1552.
    • (2006) Exp Hematol , vol.34 , pp. 1542-1552
    • Tanaka, T.1    Okabe, T.2    Gondo, S.3    Fukuda, M.4    Yamamoto, M.5    Umemura, T.6
  • 36
    • 9344233282 scopus 로고    scopus 로고
    • Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression
    • Aguilera C., Hoya-Arias R., Haegeman G., Espinosa L., Bigas A. Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression. Proc Natl Acad Sci USA 2004, 101:16537-16542.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16537-16542
    • Aguilera, C.1    Hoya-Arias, R.2    Haegeman, G.3    Espinosa, L.4    Bigas, A.5
  • 37
    • 64849102392 scopus 로고    scopus 로고
    • Levels of glucocorticoid receptor and its ligand determine sensitivity and kinetics of glucocorticoid-induced leukemia apoptosis
    • Gruber G., Carlet M., Turtscher E., Meister B., Irving J.A., Ploner C., et al. Levels of glucocorticoid receptor and its ligand determine sensitivity and kinetics of glucocorticoid-induced leukemia apoptosis. Leukemia 2009, 23:820-823.
    • (2009) Leukemia , vol.23 , pp. 820-823
    • Gruber, G.1    Carlet, M.2    Turtscher, E.3    Meister, B.4    Irving, J.A.5    Ploner, C.6
  • 38
    • 34548093735 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells
    • Meyers J.A., Taverna J., Chaves J., Makkinje A., Lerner A. Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells. Clin Cancer Res 2007, 13:4920-4927.
    • (2007) Clin Cancer Res , vol.13 , pp. 4920-4927
    • Meyers, J.A.1    Taverna, J.2    Chaves, J.3    Makkinje, A.4    Lerner, A.5
  • 39
    • 0036721526 scopus 로고    scopus 로고
    • Potentiation of glucocorticoid receptor transcriptional activity by sumoylation
    • Le Drean Y., Mincheneau N., Le Goff P., Michel D. Potentiation of glucocorticoid receptor transcriptional activity by sumoylation. Endocrinology 2002, 143:3482-3489.
    • (2002) Endocrinology , vol.143 , pp. 3482-3489
    • Le Drean, Y.1    Mincheneau, N.2    Le Goff, P.3    Michel, D.4
  • 41
    • 58049202256 scopus 로고    scopus 로고
    • The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia
    • Pottier N., Yang W., Assem M., Panetta J.C., Pei D., Paugh S.W., et al. The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia. J Natl Cancer Inst 2008, 100:1792-1803.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1792-1803
    • Pottier, N.1    Yang, W.2    Assem, M.3    Panetta, J.C.4    Pei, D.5    Paugh, S.W.6


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