Sonic hedgehog signaling induces vascular smooth muscle cell proliferation via induction of the G1 cyclin-retinoblastoma axis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 9, 2010, Pages 1787-1794

  Li, Fenghe ^a   Duman Scheel, Molly ^b   Yang, Dong ^a   Du, Wei ^c   Zhang, Jian ^a   Zhao, Chenchao ^a   Qin, Lingfeng ^d   Xin, Shijie ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cell cycle; hedgehog signaling; intimal hyperplasia; proliferation; vascular smooth muscle cell

Indexed keywords

BETA ACTIN; CYCLIN D1; CYCLINE; CYCLOPAMINE; RETINOBLASTOMA PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; CYCLIN E; HYBRID PROTEIN; KRUPPEL LIKE FACTOR; SHH PROTEIN, HUMAN; SHH PROTEIN, MOUSE; VERATRUM ALKALOID;

ANIMAL CELL; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CYCLIN D1 GENE; GENE; GLI2 GENE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; GENETICS; GRAFT OCCLUSION; HYPERPLASIA; JUGULAR VEIN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; SAPHENOUS VEIN; TRANSPLANTATION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYCLIN E; DISEASE MODELS, ANIMAL; G1 PHASE; GRAFT OCCLUSION, VASCULAR; HEDGEHOG PROTEINS; HUMANS; HYPERPLASIA; JUGULAR VEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; RNA INTERFERENCE; S PHASE; SAPHENOUS VEIN; SIGNAL TRANSDUCTION; VERATRUM ALKALOIDS;

EID: 77955961732     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.208520     Document Type: Article

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