Genetic inactivation of Pleiotrophin triggers amphetamine-induced cell loss in the substantia nigra and enhances amphetamine neurotoxicity in the striatum

Neuroscience

Volumn 170, Issue 1, 2010, Pages 308-316

  Gramage, E ^a   Rossi, L ^a   Granado, N ^b,c   Moratalla, R ^b,c   Herradon G ^a  

^a UNIVERSIDAD SAN PABLO CEU   (Spain)

^b INSTITUTO CAJAL   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

ERK1 2; Fyn; MDMA; Methamphetamine; Neurotoxicity; RPTP

Indexed keywords

AMPHETAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLEIOTROPHIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL LOSS; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; ENZYME PHOSPHORYLATION; GENE INACTIVATION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SUBSTANTIA NIGRA;

AMPHETAMINE; ANIMALS; CARRIER PROTEINS; CELL COUNT; CORPUS STRIATUM; CYTOKINES; GENE SILENCING; MALE; MICE; MICE, KNOCKOUT; SUBSTANTIA NIGRA;

EID: 77955927264     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.06.078     Document Type: Article

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