The neurotrophic factor pleiotrophin modulates amphetamine-seeking behaviour and amphetamine-induced neurotoxic effects: Evidence from pleiotrophin knockout mice

Addiction Biology

Volumn 15, Issue 4, 2010, Pages 403-412

  Gramage, Esther ^a   Putelli, Alessia ^a   Polanco, Maria J ^a   González Martín, Carmen ^a   Ezquerra, Laura ^a   Alguacil, Luis F ^a   Pérez Pinera, Pablo ^b   Deuel, Thomas F ^b   Herradón, Gonzalo ^a  

^a UNIVERSIDAD SAN PABLO CEU   (Spain)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

beta catenin; cocaine; ERK1 2; MDMA; methamphetamine; RPTP

Indexed keywords

AMPHETAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PLEIOTROPHIN; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTOSIS; CELL CULTURE; CELL STRAIN; CELL VIABILITY; CONDITIONING; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME PHOSPHORYLATION; HELP SEEKING BEHAVIOR; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE;

AMPHETAMINE; AMPHETAMINE-RELATED DISORDERS; ANIMALS; CARRIER PROTEINS; CELL SURVIVAL; CONDITIONING, CLASSICAL; CORPUS STRIATUM; CYTOKINES; DOPAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOTIVATION; NUCLEUS ACCUMBENS; PC12 CELLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

EID: 77955921552     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2009.00202.x     Document Type: Article

References (51)

1. Alonso E, Garrido E, Diez-Fernandez C, Perez-Garcia C, Herradon G, Ezquerra L, Deuel TF, Alguacil LF, (2007) Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus. Neurosci Lett 412: 163-167.
2. Amet LE, Lauri SE, Hienola A, Croll SD, Lu Y, Levorse JM, Prabhakaran B, Taira T, Rauvala H, Vogt TF, (2001) Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule. Mol Cell Neurosci 17: 1014-1024.
3. Berglind WJ, See RE, Fuchs RA, Ghee SM, Whitfield TW, Jr, Miller SW, McGinty JF, (2007) A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats. Eur J Neurosci 26: 757-766.
4. Bolanos CA, Nestler EJ, (2004) Neurotrophic mechanisms in drug addiction. Neuromolecular Med 5: 69-83.
5. Bowyer JF, Frame LT, Clausing P, Nagamoto-Combs K, Osterhout CA, Sterling CR, Tank AW, (1998) Long-term effects of amphetamine neurotoxicity on tyrosine hydroxylase mRNA and protein in aged rats. J Pharmacol Exp Ther 286: 1074-1085.
6. Corominas M, Roncero C, Ribases M, Castells X, Casas M, (2007) Brain-derived neurotrophic factor and its intracellular signaling pathways in cocaine addiction. Neuropsychobiology 55: 2-13.
7. Del Olmo N, Gramage E, Alguacil LF, Pérez-Pinera P, Deuel TF, Herradón G, (2009) Pleiotrophin inhibits hippocampal long-term potentiation: a role of pleiotrophin in learning and memory. Growth Factors 27: 189-194.
8. Deuel TF, Zhang N, Yeh HJ, Silos-Santiago I, Wang ZY, (2002) Pleiotrophin: a cytokine with diverse functions and a novel signaling pathway. Arch Biochem Biophys 397: 162-171.
9. Di Segni A, Farin K, Pinkas-Kramarski R, (2006) ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling. J Mol Neurosci 29: 257-267.
10. Ezquerra L, Perez-Garcia C, Garrido E, Diez-Fernandez C, Deuel TF, Alguacil LF, Herradón G, (2007) Morphine and yohimbine regulate midkine gene expression in the rat hippocampus. Eur J Pharmacol 557: 147-150.
11. Flatscher-Bader T, Wilce PA, (2006) Chronic smoking and alcoholism change expression of selective genes in the human prefrontal cortex. Alcohol Clin Exp Res 30: 908-915.
12. Flatscher-Bader T, Wilce PA, (2008) Impact of alcohol abuse on protein expression of midkine and excitatory amino acid transporter 1 in the human prefrontal cortex. Alcohol Clin Exp Res 32: 1849-1858.
13. Fumagalli F, Di Pasquale L, Caffino L, Racagni G, Riva MA, (2007) Repeated exposure to cocaine differently modulates BDNF mRNA and protein levels in rat striatum and prefrontal cortex. Eur J Neurosci 26: 2756-2763.
14. Gottschalk PC, Jacobsen LK, Kosten TR, (1999) Current concepts in pharmacotherapy of substance abuse. Curr Psychiatry Rep 1: 172-178.
15. Gramage E, Alguacil LF, Herradon G, (2008) Pleiotrophin prevents cocaine-induced toxicity in vitro. Eur J Pharmacol 595: 35-38.
16. Greene LA, Tischler AS, (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 73: 2424-2428.
17. Herradon G, Ezquerra L, (2009) Blocking receptor protein tyrosine phosphatase beta/zeta: a potential therapeutic strategy for Parkinson's disease. Curr Med Chem 16: 3322-3329.
18. Herradon G, Ezquerra L, Gramage E, Alguacil LF, (2009) Targeting the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta signaling pathway to limit neurotoxicity induced by drug abuse. Mini Rev Med Chem 9: 440-447.
19. Herradon G, Ezquerra L, Nguyen T, Silos-Santiago I, Deuel TF, (2005) Midkine regulates pleiotrophin organ-specific gene expression: evidence for transcriptional regulation and functional redundancy within the pleiotrophin/midkine developmental gene family. Biochem Biophys Res Commun 333: 714-721.
20. Herradon G, Ezquerra L, Nguyen T, Vogt TF, Bronson R, Silos-Santiago I, Deuel TF, (2004) Pleiotrophin is an important regulator of the renin-angiotensin system in mouse aorta. Biochem Biophys Res Commun 324: 1041-1047. (Pubitemid 39361613)
21. Hida H, Jung CG, Wu CZ, Kim HJ, Kodama Y, Masuda T, Nishino H, (2003) Pleiotrophin exhibits a trophic effect on survival of dopaminergic neurons in vitro. Eur J Neurosci 17: 2127-2134.
22. Hida H, Masuda T, Sato T, Kim TS, Misumi S, Nishino H, (2007) Pleiotrophin promotes functional recovery after neural transplantation in rats. Neuroreport 18: 179-183.
23. Hienola A, Pekkanen M, Raulo E, Vanttola P, Rauvala H, (2004) HB-GAM inhibits proliferation and enhances differentiation of neural stem cells. Mol Cell Neurosci 26: 75-88.
24. Imam SZ, Duhart HM, Skinner JT, Ali SF, (2005) Cocaine induces a differential dose-dependent alteration in the expression profile of immediate early genes, transcription factors, and caspases in PC12 cells: a possible mechanism of neurotoxic damage in cocaine addiction. Ann N Y Acad Sci 1053: 482-490.
25. Jung CG, Hida H, Nakahira K, Ikenaka K, Kim HJ, Nishino H, (2004) Pleiotrophin mRNA is highly expressed in neural stem (progenitor) cells of mouse ventral mesencephalon and the product promotes production of dopaminergic neurons from embryonic stem cell-derived nestin-positive cells. FASEB J 18: 1237-1239.
26. Kadota T, Yamaai T, Saito Y, Akita Y, Kawashima S, Moroi K, Inagaki N, Kadota K, (1996) Expression of dopamine transporter at the tips of growing neurites of PC12 cells. J Histochem Cytochem 44: 989-996.
27. Krasnova IN, Ladenheim B, Cadet JL, (2005) Amphetamine induces apoptosis of medium spiny striatal projection neurons via the mitochondria-dependent pathway. FASEB J 19: 851-853.
28. Le Greves P, (2005) Pleiotrophin gene transcription in the rat nucleus accumbens is stimulated by an acute dose of amphetamine. Brain Res Bull 65: 529-532.
29. Lepsch LB, Munhoz CD, Kawamoto EM, Yshii LM, Lima LS, Curi-Boaventura MF, Salgado TM, Curi R, Planeta CS, Scavone C, (2009) Cocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells. Mol Brain 2: 3.
30. Li YS, Milner PG, Chauhan AK, Watson MA, Hoffman RM, Kodner CM, Milbrandt J, Deuel TF, (1990) Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science 250: 1690-1694.
31. Liu C, Wang Y, Smallwood PM, Nathans J, (2008) An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. J Neurosci 28: 5641-5653.
32. Lynch WJ, Girgenti MJ, Breslin FJ, Newton SS, Taylor JR, (2008) Gene profiling the response to repeated cocaine self-administration in dorsal striatum: a focus on circadian genes. Brain Res 1213: 166-177.
33. Mailleux P, Preud'homme X, Albala N, Vanderwinden JM, Vanderhaeghen JJ, (1994) delta-9-Tetrahydrocannabinol regulates gene expression of the growth factor pleiotrophin in the forebrain. Neurosci Lett 175: 25-27.
34. Marchionini DM, Lehrmann E, Chu Y, He B, Sortwell CE, Becker KG, Freed WJ, Kordower JH, Collier TJ, (2007) Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease. Brain Res 1147: 77-88.
35. Meng K, Rodriguez-Pena A, Dimitrov T, Chen W, Yamin M, Noda M, Deuel TF, (2000) Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta. Proc Natl Acad Sci U S A 97: 2603-2608.
36. Milner PG, Li YS, Hoffman RM, Kodner CM, Siegel NR, Deuel TF, (1989) A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: purification and N-terminal amino acid sequence. Biochem Biophys Res Commun 165: 1096-1103.
37. Morales L, Perez-Garcia C, Herradon G, Alguacil LF, (2007) Place conditioning in a two- or three-conditioning compartment apparatus: a comparative study with morphine and U-50,488. Addict Biol 12: 482-484.
38. Narita M, Miyatake M, Shibasaki M, Tsuda M, Koizumi S, Narita M, Yajima Y, Inoue K, Suzuki T, (2005) Long-lasting change in brain dynamics induced by methamphetamine: enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization. J Neurochem 93: 1383-1392.
39. Narita M, Suzuki M, Kuzumaki N, Miyatake M, Suzuki T, (2008) Implication of activated astrocytes in the development of drug dependence: differences between methamphetamine and morphine. Ann N Y Acad Sci 1141: 96-104.
40. Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Muller-Esterl W, Zeuzem S, (2002) Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. J Biol Chem 277: 43623-43630.
41. Pu C, Vorhees CV, (1995) Protective effects of MK-801 on methamphetamine-induced depletion of dopaminergic and serotonergic terminals and striatal astrocytic response: an immunohistochemical study. Synapse 19: 97-104.
42. Rauvala H, (1989) An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J 8: 2933-2941.
43. Ricaurte GA, Mechan AO, Yuan J, Hatzidimitriou G, Xie T, Mayne AH, McCann UD, (2005) Amphetamine treatment similar to that used in the treatment of adult attention-deficit/hyperactivity disorder damages dopaminergic nerve endings in the striatum of adult nonhuman primates. J Pharmacol Exp Ther 315: 91-98.
44. Ridet JL, Malhotra SK, Privat A, Gage FH, (1997) Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20: 570-577.
45. Sulzer D, Sonders MS, Poulsen NW, Galli A, (2005) Mechanisms of neurotransmitter release by amphetamines: a review. Prog Neurobiol 75: 406-433.
46. Taravini IR, Ferrario JE, Delbe J, Ginestet L, Debeir T, Courty J, Murer MG, Gershanik OS, Raisman-Vozari R, (2005) Immunodetection of heparin-binding growth associated molecule (pleiotrophin) in striatal interneurons. Brain Res 1066: 196-200.
47. Tiihonen J, Kuoppasalmi K, Fohr J, Tuomola P, Kuikanmaki O, Vorma H, Sokero P, Haukka J, Meririnne E, (2007) A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence. Am J Psychiatry 164: 160-162.
48. Tosk JM, Farag M, Ho JY, Lee CC, Maximos BB, Yung HH, (1996) The effects of nerve growth factor and ganglioside GM1 on the anti-proliferative activity of cocaine in PC12 cells. Life Sci 59: 1731-1737.
49. Tzschentke TM, (2007) Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict Biol 12: 227-462.
50. White FJ, Kalivas PW, (1998) Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend 51: 141-153.
51. Yamamoto BK, Bankson MG, (2005) Amphetamine neurotoxicity: cause and consequence of oxidative stress. Crit Rev Neurobiol 17: 87-117.