Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: Role of mitochondrial ATP-sensitive potassium channels, Akt and ERK

Journal of Neurochemistry

Volumn 104, Issue 4, 2008, Pages 914-925

  Goñi Allo, Beatriz ^a   Puerta, Elena ^a   Ramos, María ^a   Lasheras, Berta ^a   Jordán, Joaquín ^b   Aguirre, Norberto ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

3,4 methylenedioxymethamphetamine; 5 hydroxytryptamine; Akt; Extracellular signal regulated kinase; Minoxidil; Mitochondrial ATP sensitive potassium channels

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; AMPHETAMINE DERIVATIVE; CLAMIKALANT; INDOLE; MINOXIDIL; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN KINASE B; SEROTONIN; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORE TEMPERATURE; CORPUS STRIATUM; HYPERTHERMIA; MALE; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOLEMMA;

ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; KATP CHANNELS; MALE; MINOXIDIL; MITOCHONDRIA; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; POTASSIUM CHANNELS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SEROTONIN;

RATTUS;

EID: 38449090057     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05042.x     Document Type: Article

References (54)

1. Aguirre N., Galbete J. L., Lasheras B. Del Rio J. (1995) Methylenedioxymethamphetamine induces opposite changes in central pre- and postsynaptic 5-HT1A receptors in rats. Eur. J. Pharmacol. 281, 101 105.
2. Aguirre N., Barrionuevo M., Ramirez M. J., Del Rio J. Lasheras B. (1999) alpha-Lipoic acid prevents 3,4-Methylenedioxymethamphetamine (MDMA)-induced neurotoxicity. Neuroreport 10, 3675 3680.
3. Andoh T., Chock P. B. Chiueh C. C. (2002) Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression. Ann. N Y Acad. Sci. 962, 1 7.
4. Bolduc C. Shapiro J. (2000) Management of androgenetic alopecia. Am. J. Clin. Dermatol. 1, 151 158.
5. Busija D. W., Lacza Z., Rajapakse N., Shimizu K., Kis B., Bari F., Domoki F. Horiguchi T. (2004) Targeting mitochondrial ATP-sensitive potassium channels-a novel approach to neuroprotection. Brain Res. Brain Res. Rev. 46, 282 294.
6. Colado M. I., O'Shea E., Granados R., Murray T. K. Green A. R. (1997) In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine. Br. J. Pharmacol. 121, 889 900.
7. Costa A. D., Garlid K. D., West I. C., Lincoln T. M., Downey J. M., Cohen M. V. Critz S. D. (2005) Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria. Circ. Res. 97, 329 336.
8. Das A., Smolenski A., Lohmann S. M. Kukreja R. C. (2006) Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. J. Biol. Chem. 281, 38644 38652.
9. Dirnagl U., Simon R. P. Hallenbeck J. M. (2003) Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 26, 248 254.
10. Fernandez-Gomez F. J., Pastor M. D., Garcia-Martinez E. M., Melero-Fernandez de Mera R., Gou-Fabregas M., Gomez-Lazaro M., Calvo S., Soler R. M., Galindo M. F. Jordan J. (2006) Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression. Neurobiol. Dis. 24, 296 307.
11. Fryer R. M., Eells J. T., Hsu A. K., Henry M. M. Gross G. J. (2000) Ischemic preconditioning in rats: role of mitochondrial K(ATP) channel in preservation of mitochondrial function. Am. J. Physiol. Heart Circ. Physiol. 278, H305 H312.
12. Gidday J. M. (2006) Cerebral preconditioning and ischaemic tolerance. Nat. Rev. Neurosci. 7, 437 448.
13. Gok S., Vatansever S., Vural K., Sekuri C., Izanli A., Tezcan A. Cilaker S. (2006) The role of ATP sensitive K+ channels and of nitric oxide synthase on myocardial ischemia/reperfusion-induced apoptosis. Acta Histochem. 108, 95 104.
14. Goñi-Allo B., Ramos M., Hervias I., Lasheras B. Aguirre N. (2006) Studies on striatal neurotoxicity caused by the 3,4- methylenedioxymethamphetamine/malonate combination: implications for serotonin/dopamine interactions. J. Psychopharmacol. 20, 245 256.
15. Goñi-Allo B., Puerta E., Hervias I., Di Palma R., Ramos M., Lasheras B. Aguirre N. (2007) Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats. Eur. J. Pharmacol. 562, 198 207.
16. Gonzalez-Zulueta M., Feldman A. B., Klesse L. J., Kalb R. G., Dillman J. F., Parada L. F., Dawson T. M. Dawson V. L. (2000) Requirement for nitric oxide activation of p21ras/extracellular regulated kinase in neuronal ischemic preconditioning. Proc. Natl Acad. Sci. USA 97, 436 441.
17. Green A. R., Mechan A. O., Elliott J. M., O'Shea E. Colado M. I. (2003) The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol. Rev. 55, 463 508.
18. Greene J. G. Greenamyre J. T. (1996) Manipulation of membrane potential modulates malonate-induced striatal excitotoxicity in vivo. J. Neurochem. 66, 637 643.
19. Gross G. J. Fryer R. M. (1999) Sarcolemmal versus mitochondrial ATP-sensitive K+ channels and myocardial preconditioning. Circ. Res. 84, 973 979.
20. Han H., Wang H., Long H., Nattel S. Wang Z. (2001) Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases. J. Biol. Chem. 276, 26357 26364.
21. Han J. H., Kwon O. S., Chung J. H., Cho K. H., Eun H. C. Kim K. H. (2004) Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle. J. Dermatol. Sci. 34, 91 98.
22. Hatzdimitrou G., McCann U. D. Ricaurte G. A. (1999) Altered serotonin innervation patterns in the forebrain of monkeys with (+/-) 3,4- methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery. J. Neurosci. 19, 5096 5107.
23. Hausenloy D. J., Mocanu M. M. Yellon D. M. (2004) Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning. Cardiovasc. Res. 63, 305 312.
24. Hervias I., Lasheras B. Aguirre N. (2000) 2-Deoxy-D-Glugose prevents and nicotinamide potentiates 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity. J. Neurochem. 75, 982 990.
25. Heurteaux C., Lauritzen I., Widmann C. Lazdunski M. (1995) Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning. Proc. Natl Acad. Sci. USA 92, 4666 4670.
26. Jones N. M. Bergeron M. (2004) Hypoxia-induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling. J. Neurochem. 89, 157 167.
27. Kennedy S. G., Wagner A. J., Conzen S. D., Jordan J., Bellacosa A., Tsichlis P. N. Hay N. (1997) The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 11, 701 713.
28. Kirino T. (2002) Ischemic tolerance. J. Cereb. Blood Flow Metab. 22, 1283 1296.
29. Kis B., Rajapakse N. C., Snipes J. A., Nagy K., Horiguchi T. Busija D. W. (2003) Diazoxide induces delayed preconditioning in cultured rat cortical neurons. J. Neurochem. 87, 969 980.
30. Kis B., Nagy K., Snipes J. A., Rajapakse N. C., Horiguchi T., Grover G. J. Busija D. W. (2004) The mitochondrial K(ATP) channel opener BMS-191095 induces neuronal preconditioning. Neuroreport 15, 345 349.
31. Leak R. K., Liou A. K. Zigmond M. J. (2006) Effect of sublethal 6-hydroxydopamine on the response to subsequent oxidative stress in dopaminergic cells: evidence for preconditioning. J. Neurochem. 99, 1151 1163.
32. Liu D., Lu C., Wan R., Auyeung W. W. Mattson M. P. (2002) Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 22, 431 443.
33. Mattson M. P. Magnus T. (2006) Ageing and neuronal vulnerability. Nat. Rev. Neurosci. 7, 278 294.
34. Mayanagi K., Gaspar T., Katakam P. V., Kis B. Busija D. W. (2007) The mitochondrial K(ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 27, 348 355.
35. McCann U. D., Szabo Z., Scheffel U., Dannals R. F. Ricaurte G. A. (1998) Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings. Lancet 352, 1433 1437.
36. Miao B., Yin X. H., Pei D. S., Zhang Q. G. Zhang G. Y. (2005) Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation. J. Biol. Chem. 280, 21693 21699.
37. Nagy K., Kis B., Rajapakse N. C., Bari F. Busija D. W. (2004) Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation. J. Neurosci. Res. 76, 697 704.
38. O'Rourke B. (2000) Myocardial K(ATP) channels in preconditioning. Circ. Res. 87, 845 855.
39. O'Shea E., Orio L., Escobedo I., Sanchez V., Camarero J., Green A. R. Colado M. I. (2006) MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature. Br. J. Pharmacol. 148, 778 785.
40. Paxinos G. Watson C. (1997) The Rat Brain in Sterotaxic Coordinates. Academic Press, San Diego.
41. Polleselloa P. Mebazaab A. (2004) ATP-dependent potassium channels as a key target for the treatment of myocardial and vascular dysfunction. Curr. Opin. Crit. Care 10, 436 441.
42. Rahmouni K., Morgan D. A., Morgan G. M., Liu X., Sigmund C. D., Mark A. L. Haynes W. G. (2004) Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin. J. Clin. Invest. 114, 652 658.
43. Salzmann J., Marie-Claire C., Le Guen S., Roques B. P. Noble F. (2003) Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice. Br. J. Pharmacol. 140, 831 838.
44. Salzmann J., Canestrelli C., Noble F. Marie-Claire C. (2006) Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes. Neuroscience 137, 473 482.
45. Sato T., Li Y., Saito T. Nakaya H. (2004) Minoxidil opens mitochondrial K(ATP) channels and confers cardioprotection. Br. J. Pharmacol. 141, 360 366.
46. Shamloo M., Rytter A. Wieloch T. (1999) Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning. Neuroscience 93, 81 88.
47. Shankaran M., Yamamoto B. K. Gudelsky G. A. (1999) Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine. Eur. J. Pharmacol. 385, 103 110.
48. Shankaran M., Yamamoto B. K. Gudelsky G. A. (2001) Ascorbic acid prevents 3,4-methylenedioxymethamphetamine (MDMA)-induced hydroxyl radical formation and the behavioral and neurochemical consequences of the depletion of brain 5-HT. Synapse 40, 55 64.
49. Sharp F. R., Ran R., Lu A., Tang Y., Strauss K. I., Glass T., Ardizzone T. Bernaudin M. (2004) Hypoxic preconditioning protects against ischemic brain injury. NeuroRx 1, 26 35.
50. Shimizu K., Lacza Z., Rajapakse N., Horiguchi T., Snipes J. Busija D. W. (2002) MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat. Am. J. Physiol. 283, H1005 H1011.
51. Teshima Y., Akao M., Li R. A., Chong T. H., Baumgartner W. A., Johnston M. V. Marban E. (2003) Mitochondrial ATPsensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress. Stroke 34, 1796 1802.
52. Testai L., Rapposelli S. Calderone V. (2007) Cardiac ATP-sensitive potassium channels: a potential target for an anti-ischaemic pharmacological strategy. Cardiovasc. Hematol. Agents Med. Chem. 5, 79 90.
53. Yano S., Morioka M., Fukunaga K., Kawano T., Hara T., Kai Y., Hamada J., Miyamoto E. Ushio Y. (2001) Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus. J. Cereb. Blood Flow Metab. 21, 351 360.
54. Yoon S. Seger R. (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24, 21 44.