An ATP-independent strategy for amide bond formation in antibiotic biosynthesis

Nature Chemical Biology

Volumn 6, Issue 8, 2010, Pages 581-586

  Funabashi, Masanori ^a   Yang, Zhaoyong ^b   Nonaka, Koichi ^a   Hosobuchi, Masahiko ^a   Fujita, Yoko ^a   Shibata, Tomoyuki ^a   Chi, Xiuling ^b   Van Lanen, Steven G ^b  

^a DAIICHI SANKYO CO   (Japan)

^b University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 503083B; BETA LACTAMASE; CAPROLACTAM DERIVATIVE; CAPURAMYCIN; CARBOXYLTRANSFERASE; UNCLASSIFIED DRUG; A 503083 A; ADENOSINE TRIPHOSPHATE; AMIDE; ANTIINFECTIVE AGENT; AZEPINE DERIVATIVE; BACTERIAL DNA; CARBOXYLIC ACID; DRUG DERIVATIVE; ESTER; LYSINE; PROTEIN METHYLTRANSFERASE; URIDINE;

ARTICLE; BIOSYNTHESIS; CHEMICAL BOND; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ESTERIFICATION; GENE CLUSTER; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; CATALYSIS; CHEMISTRY; GENE LIBRARY; GENETICS; HYDROLYSIS; KINETICS; METABOLISM; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; STREPTOMYCES;

ADENOSINE TRIPHOSPHATE; AMIDES; ANTI-BACTERIAL AGENTS; AZEPINES; BETA-LACTAMASES; CARBOXYLIC ACIDS; CATALYSIS; CLONING, MOLECULAR; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; ESTERS; GENE LIBRARY; HYDROLYSIS; KINETICS; LYSINE; MULTIGENE FAMILY; PROTEIN O-METHYLTRANSFERASE; STREPTOMYCES; URIDINE;

EID: 77955919815     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.393     Document Type: Article

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