-
1
-
-
0036546066
-
New concepts in the immunopathogenesis of multiple sclerosis
-
Hemmer B., Archelos J.J., Hartung H.P. New concepts in the immunopathogenesis of multiple sclerosis. Nat Rev Neurosci 2002, 3:291-301.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 291-301
-
-
Hemmer, B.1
Archelos, J.J.2
Hartung, H.P.3
-
2
-
-
0037882036
-
Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year
-
Steinman L. Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year. J Exp Med 2003, 197:1065-1071.
-
(2003)
J Exp Med
, vol.197
, pp. 1065-1071
-
-
Steinman, L.1
-
3
-
-
0019465748
-
Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes
-
Pettinelli C.B., McFarlin D.E. Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes. J Immunol 1981, 127:1420-1423.
-
(1981)
J Immunol
, vol.127
, pp. 1420-1423
-
-
Pettinelli, C.B.1
McFarlin, D.E.2
-
4
-
-
0021966856
-
T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination
-
Zamvil S., Nelson P., Trotter J., Mitchell D., Knobler R., Fritz R., et al. T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination. Nature 1985, 317:355-358.
-
(1985)
Nature
, vol.317
, pp. 355-358
-
-
Zamvil, S.1
Nelson, P.2
Trotter, J.3
Mitchell, D.4
Knobler, R.5
Fritz, R.6
-
5
-
-
0023931606
-
Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
-
Linington C., Bradl M., Lassmann H., Brunner C., Vass K. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am J Pathol 1988, 130:443-454.
-
(1988)
Am J Pathol
, vol.130
, pp. 443-454
-
-
Linington, C.1
Bradl, M.2
Lassmann, H.3
Brunner, C.4
Vass, K.5
-
6
-
-
0032839687
-
Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation
-
Raine C.S., Cannella B., Hauser S.L., Genain C.P. Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation. Ann Neurol 1999, 46:144-160.
-
(1999)
Ann Neurol
, vol.46
, pp. 144-160
-
-
Raine, C.S.1
Cannella, B.2
Hauser, S.L.3
Genain, C.P.4
-
7
-
-
0032167731
-
Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis
-
Qin Y., Duquette P., Zhang Y., Talbot P., Poole R., Antel J. Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis. J Clin Invest 1998, 102:1045-1050.
-
(1998)
J Clin Invest
, vol.102
, pp. 1045-1050
-
-
Qin, Y.1
Duquette, P.2
Zhang, Y.3
Talbot, P.4
Poole, R.5
Antel, J.6
-
8
-
-
0034724380
-
Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response
-
Smith-Jensen T., Burgoon M.P., Anthony J., Kraus H., Gilden D.H., Owens G.P. Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response. Neurology 2000, 54:1227-1232.
-
(2000)
Neurology
, vol.54
, pp. 1227-1232
-
-
Smith-Jensen, T.1
Burgoon, M.P.2
Anthony, J.3
Kraus, H.4
Gilden, D.H.5
Owens, G.P.6
-
9
-
-
0015529001
-
Protection against experimental allergic encephalomyelitis
-
Teitelbaum D., Webb C., Meshorer A., Arnon R., Sela M. Protection against experimental allergic encephalomyelitis. Nature 1972, 240:564-566.
-
(1972)
Nature
, vol.240
, pp. 564-566
-
-
Teitelbaum, D.1
Webb, C.2
Meshorer, A.3
Arnon, R.4
Sela, M.5
-
10
-
-
0023275609
-
Suppression of acute and relapsing experimental allergic encephalomyelitis with mitoxantrone
-
Lublin F.D., Lavasa M., Viti C., Knobler R.L. Suppression of acute and relapsing experimental allergic encephalomyelitis with mitoxantrone. Clin Immunol Immunopathol 1987, 45:122-128.
-
(1987)
Clin Immunol Immunopathol
, vol.45
, pp. 122-128
-
-
Lublin, F.D.1
Lavasa, M.2
Viti, C.3
Knobler, R.L.4
-
11
-
-
0029670711
-
Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis
-
Yu M., Nishiyama A., Trapp B.D., Tuohy V.K. Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis. J Neuroimmunol 1996, 64:91-100.
-
(1996)
J Neuroimmunol
, vol.64
, pp. 91-100
-
-
Yu, M.1
Nishiyama, A.2
Trapp, B.D.3
Tuohy, V.K.4
-
12
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
Yednock T.A., Cannon C., Fritz L.C., Sanchez-Madrid F., Steinman L., Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992, 356:63-66.
-
(1992)
Nature
, vol.356
, pp. 63-66
-
-
Yednock, T.A.1
Cannon, C.2
Fritz, L.C.3
Sanchez-Madrid, F.4
Steinman, L.5
Karin, N.6
-
13
-
-
45549092100
-
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis
-
Oksenberg J.R., Baranzini S.E., Sawcer S., Hauser S.L. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet 2008, 9:516-526.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 516-526
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
Sawcer, S.3
Hauser, S.L.4
-
14
-
-
0031093505
-
Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients
-
Zambidis E.T., Barth R.K., Scott D.W. Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients. J Immunol 1997, 158:2174-2182.
-
(1997)
J Immunol
, vol.158
, pp. 2174-2182
-
-
Zambidis, E.T.1
Barth, R.K.2
Scott, D.W.3
-
15
-
-
0036569428
-
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases
-
Melo M.E., Qian J., El-Amine M., Agarwal R.K., Soukhareva N., Kang Y., et al. Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases. J Immunol 2002, 168:4788-4795.
-
(2002)
J Immunol
, vol.168
, pp. 4788-4795
-
-
Melo, M.E.1
Qian, J.2
El-Amine, M.3
Agarwal, R.K.4
Soukhareva, N.5
Kang, Y.6
-
16
-
-
1842685036
-
A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP
-
Xu B., Scott D.W. A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP. Clin Immunol 2004, 111:47-52.
-
(2004)
Clin Immunol
, vol.111
, pp. 47-52
-
-
Xu, B.1
Scott, D.W.2
-
17
-
-
28844477590
-
Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE
-
Xu B., Haviernik P., Wolfraim L.A., Bunting K.D., Scott D.W. Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE. Mol Ther 2006, 13:42-48.
-
(2006)
Mol Ther
, vol.13
, pp. 42-48
-
-
Xu, B.1
Haviernik, P.2
Wolfraim, L.A.3
Bunting, K.D.4
Scott, D.W.5
-
18
-
-
5444221869
-
Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?
-
Song L., Wang J., Wang R., Yu M., Sun Y., Han G., et al. Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?. Gene Ther 2004, 11:1487-1496.
-
(2004)
Gene Ther
, vol.11
, pp. 1487-1496
-
-
Song, L.1
Wang, J.2
Wang, R.3
Yu, M.4
Sun, Y.5
Han, G.6
-
19
-
-
20444476217
-
Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins
-
Lei T.C., Scott D.W. Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins. Blood 2005, 105:4865-4870.
-
(2005)
Blood
, vol.105
, pp. 4865-4870
-
-
Lei, T.C.1
Scott, D.W.2
-
20
-
-
29444447786
-
B-cell delivered gene transfer of human S-Ag-Ig fusion protein protects from experimental autoimmune uveitis
-
Liang W., Karabekian Z., Mattapallil M., Xu Q., Viley A.M., Caspi R., et al. B-cell delivered gene transfer of human S-Ag-Ig fusion protein protects from experimental autoimmune uveitis. Clin Immunol 2006, 118:35-41.
-
(2006)
Clin Immunol
, vol.118
, pp. 35-41
-
-
Liang, W.1
Karabekian, Z.2
Mattapallil, M.3
Xu, Q.4
Viley, A.M.5
Caspi, R.6
-
21
-
-
33747842285
-
Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: role of T regulatory cells
-
Soukhareva N., Jiang Y., Scott D.W. Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: role of T regulatory cells. Cell Immunol 2006, 240:41-46.
-
(2006)
Cell Immunol
, vol.240
, pp. 41-46
-
-
Soukhareva, N.1
Jiang, Y.2
Scott, D.W.3
-
22
-
-
0033927572
-
Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis
-
Agarwal R.K., Kang Y., Zambidis E., Scott D.W., Chan C.C., Caspi R.R. Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis. J Clin Invest 2000, 106:245-252.
-
(2000)
J Clin Invest
, vol.106
, pp. 245-252
-
-
Agarwal, R.K.1
Kang, Y.2
Zambidis, E.3
Scott, D.W.4
Chan, C.C.5
Caspi, R.R.6
-
23
-
-
34248548655
-
Mycobacterial Hsp65-IgG-expressing tolerogenic B cells confer protection against adjuvant-induced arthritis in Lewis rats
-
Satpute S.R., Soukhareva N., Scott D.W., Moudgil K.D. Mycobacterial Hsp65-IgG-expressing tolerogenic B cells confer protection against adjuvant-induced arthritis in Lewis rats. Arthritis Rheum 2007, 56:1490-1496.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1490-1496
-
-
Satpute, S.R.1
Soukhareva, N.2
Scott, D.W.3
Moudgil, K.D.4
-
24
-
-
2942625421
-
Complete protection from relapsing experimental autoimmune encephalomyelitis induced by syngeneic B cells expressing the autoantigen
-
Chen C.C., Rivera A., Dougherty J.P., Ron Y. Complete protection from relapsing experimental autoimmune encephalomyelitis induced by syngeneic B cells expressing the autoantigen. Blood 2004, 103:4616-4618.
-
(2004)
Blood
, vol.103
, pp. 4616-4618
-
-
Chen, C.C.1
Rivera, A.2
Dougherty, J.P.3
Ron, Y.4
-
25
-
-
76249132172
-
In vivo induction of type 1-like regulatory T cells using genetically modified B cells confers long-term IL-10-dependent antigen-specific unresponsiveness
-
Ahangarani R.R., Janssens W., VanderElst L., Carlier V., VandenDriessche T., Chuah M., et al. In vivo induction of type 1-like regulatory T cells using genetically modified B cells confers long-term IL-10-dependent antigen-specific unresponsiveness. J Immunol 2009, 183:8232-8243.
-
(2009)
J Immunol
, vol.183
, pp. 8232-8243
-
-
Ahangarani, R.R.1
Janssens, W.2
VanderElst, L.3
Carlier, V.4
VandenDriessche, T.5
Chuah, M.6
-
26
-
-
0034669953
-
Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells
-
El-Amine M., Melo M., Kang Y., Nguyen H., Qian J., Scott D.W. Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells. J Immunol 2000, 165:5631-5636.
-
(2000)
J Immunol
, vol.165
, pp. 5631-5636
-
-
El-Amine, M.1
Melo, M.2
Kang, Y.3
Nguyen, H.4
Qian, J.5
Scott, D.W.6
-
27
-
-
23244454645
-
Mechanisms of gene therapy for tolerance: B7 signaling is required for peptide-IgG gene-transferred tolerance induction
-
Litzinger M.T., Su Y., Lei T.C., Soukhareva N., Scott D.W. Mechanisms of gene therapy for tolerance: B7 signaling is required for peptide-IgG gene-transferred tolerance induction. J Immunol 2005, 175:780-787.
-
(2005)
J Immunol
, vol.175
, pp. 780-787
-
-
Litzinger, M.T.1
Su, Y.2
Lei, T.C.3
Soukhareva, N.4
Scott, D.W.5
-
28
-
-
49049122300
-
B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway
-
Su Y., Carey G., Maric M., Scott D.W. B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway. J Immunol 2008, 181:1153-1160.
-
(2008)
J Immunol
, vol.181
, pp. 1153-1160
-
-
Su, Y.1
Carey, G.2
Maric, M.3
Scott, D.W.4
-
29
-
-
77955176519
-
B-cell delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells
-
May 18 [Epub ahead of print]
-
Skupsky J., Zhang A.H., Su Y., Scott D.W. B-cell delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells. Mol Ther 2010, May 18 [Epub ahead of print].
-
(2010)
Mol Ther
-
-
Skupsky, J.1
Zhang, A.H.2
Su, Y.3
Scott, D.W.4
-
30
-
-
2642638773
-
B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice
-
Litzenburger T., Fassler R., Bauer J., Lassmann H., Linington C., Wekerle H., et al. B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J Exp Med 1998, 188:169-180.
-
(1998)
J Exp Med
, vol.188
, pp. 169-180
-
-
Litzenburger, T.1
Fassler, R.2
Bauer, J.3
Lassmann, H.4
Linington, C.5
Wekerle, H.6
-
31
-
-
0035889964
-
B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice
-
Hulbert C., Riseili B., Rojas M., Thomas J.W. B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice. J Immunol 2001, 167:5535-5538.
-
(2001)
J Immunol
, vol.167
, pp. 5535-5538
-
-
Hulbert, C.1
Riseili, B.2
Rojas, M.3
Thomas, J.W.4
-
32
-
-
0028006884
-
Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice
-
Amor S., Groome N., Linington C., Morris M.M., Dornmair K., Gardinier M.V., et al. Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. J Immunol 1994, 153:4349-4356.
-
(1994)
J Immunol
, vol.153
, pp. 4349-4356
-
-
Amor, S.1
Groome, N.2
Linington, C.3
Morris, M.M.4
Dornmair, K.5
Gardinier, M.V.6
-
33
-
-
34248647881
-
Active induction of experimental allergic encephalomyelitis
-
Stromnes I.M., Goverman J.M. Active induction of experimental allergic encephalomyelitis. Nat Protoc 2006, 1:1810-1819.
-
(2006)
Nat Protoc
, vol.1
, pp. 1810-1819
-
-
Stromnes, I.M.1
Goverman, J.M.2
|