Dose and time-dependent hypercholesterolemic effects of iodine excess via TRβ1-mediated down regulation of hepatic LDLr gene expression

European Journal of Nutrition

Volumn 49, Issue 5, 2010, Pages 257-265

  Zhao, Li Na ^a   Xu, Jian ^b   Peng, Xiao Lin ^a   Tian, Li Yue ^a   Hao, Li Ping ^a   Yang, Xue Feng ^a   Ying, Chen Jiang ^a   Sun, Xiu Fa ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Shen Zhen Center for Chronic Disease Control   (China)

Author keywords

Hypercholesterolemic; Iodine excess; Low density lipoproteins receptor (LDLr); Scavenger receptor class B type I (SR BI); Thyroid hormone receptor 1 (TR 1)

Indexed keywords

CHOLESTEROL; IODINE; LIOTHYRONINE; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; THYROID HORMONE; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA1; THYROTROPIN; THYROXINE; UNCLASSIFIED DRUG; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; CHOLESTEROL BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GENE EXPRESSION REGULATION; HYPERCHOLESTEROLEMIA; LIOTHYRONINE BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID METABOLISM; LIVER WEIGHT; LONG TERM EXPOSURE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OVERNUTRITION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; WEIGHT GAIN; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CHEMISTRY; DOSE RESPONSE; DOWN REGULATION; DRINKING; DRUG EFFECTS; EATING; GENETICS; LIVER; METABOLISM; ORGAN SIZE; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; THYROID GLAND; TIME; URINE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRINKING; EATING; FEMALE; HYPERCHOLESTEROLEMIA; IODINE; LIPIDS; LIVER; MICE; MICE, INBRED BALB C; ORGAN SIZE; POLYMERASE CHAIN REACTION; RECEPTORS, LDL; RNA, MESSENGER; THYROID GLAND; THYROID HORMONE RECEPTORS BETA; THYROID HORMONES; TIME FACTORS; WEIGHT GAIN;

MUS;

EID: 77955918492     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-009-0081-3     Document Type: Article

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