Vκ polymorphisms in NOD mice are spread throughout the entire immunoglobulin kappa locus and are shared by other autoimmune strains

Immunogenetics

Volumn 62, Issue 8, 2010, Pages 507-520

  Henry, Rachel A ^a   Kendall, Peggy L ^a   Woodward, Emily J ^a   Hulbert, Chrys ^a   Thomas, James W ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Autoimmunity; B cell; Immunoglobulin kappa; Light chain; Type 1 diabetes

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; T LYMPHOCYTE RECEPTOR; INSULIN; PRIMER DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; DNA SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; IMMUNOLOGICAL TOLERANCE; INSULIN BINDING; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; MOUSE STRAIN; NONHUMAN; NONOBESE DIABETIC MOUSE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; UNINDEXED SEQUENCE; VK GENE; AMINO ACID SUBSTITUTION; ANIMAL; GENETICS; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOGLOBULIN LIGHT CHAIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; TRANSGENIC MOUSE;

MUS;

AMINO ACID SUBSTITUTION; ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; BASE SEQUENCE; DIABETES MELLITUS, TYPE 1; DNA PRIMERS; GENES, IMMUNOGLOBULIN HEAVY CHAIN; GENES, IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INSULIN; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; T-LYMPHOCYTES;

EID: 77955885712     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-010-0457-9     Document Type: Article

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