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Volumn 299, Issue 2, 2010, Pages

The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization

Author keywords

Calcium sensitization; Calyculin A; Cytoskeleton; Myosin light chain kinase; Myosin light chain phosphatase; Myosin light chain phosphorylation; Myosin phosphatase

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; ACETYLCHOLINE; EXOENZYME C3; GUANOSINE TRIPHOSPHATASE; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PROTEIN INHIBITOR; RHOA GUANOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; ACTIN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 77955883145     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00118.2010     Document Type: Article
Times cited : (37)

References (67)
  • 1
    • 0024584734 scopus 로고
    • The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3
    • Aktories K, Braun U, Rosener S, Just I, Hall A. The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3. Biochem Biophys Res Commun 158: 209-213, 1989.
    • (1989) Biochem Biophys Res Commun , vol.158 , pp. 209-213
    • Aktories, K.1    Braun, U.2    Rosener, S.3    Just, I.4    Hall, A.5
  • 2
    • 0035865682 scopus 로고    scopus 로고
    • LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505
    • Amano T, Tanabe K, Eto T, Narumiya S, Mizuno K. LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Biochem J 354: 149-159, 2001.
    • (2001) Biochem J , vol.354 , pp. 149-159
    • Amano, T.1    Tanabe, K.2    Eto, T.3    Narumiya, S.4    Mizuno, K.5
  • 4
    • 0035930613 scopus 로고    scopus 로고
    • Exchange of the actin-bound nucleotide in intact arterial smooth muscle
    • Barany M, Barron JT, Gu L, Barany K. Exchange of the actin-bound nucleotide in intact arterial smooth muscle. J Biol Chem 276: 48398-48403, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 48398-48403
    • Barany, M.1    Barron, J.T.2    Gu, L.3    Barany, K.4
  • 5
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 116: 167-179, 2004.
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 6
  • 7
    • 0029995797 scopus 로고    scopus 로고
    • Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
    • Chrzanowska-Wodnicka M, Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133: 1403-1415, 1996.
    • (1996) J Cell Biol , vol.133 , pp. 1403-1415
    • Chrzanowska-Wodnicka, M.1    Burridge, K.2
  • 8
    • 0036135875 scopus 로고    scopus 로고
    • Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior
    • Cipolla MJ, Gokina NI, Osol G. Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior. FASEB J 16: 72-76, 2002.
    • (2002) FASEB J , vol.16 , pp. 72-76
    • Cipolla, M.J.1    Gokina, N.I.2    Osol, G.3
  • 12
    • 12344263554 scopus 로고    scopus 로고
    • Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction
    • Flavahan NA, Bailey SR, Flavahan WA, Mitra S, Flavahan S. Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction. Am J Physiol Heart Circ Physiol 288: H660-H669, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Flavahan, N.A.1    Bailey, S.R.2    Flavahan, W.A.3    Mitra, S.4    Flavahan, S.5
  • 13
    • 0029892628 scopus 로고    scopus 로고
    • Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin
    • Flinn HM, Ridley AJ. Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin. J Cell Sci 109: 1133-1141, 1996.
    • (1996) J Cell Sci , vol.109 , pp. 1133-1141
    • Flinn, H.M.1    Ridley, A.J.2
  • 14
    • 0030721443 scopus 로고    scopus 로고
    • Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B
    • Fujihara H, Walker LA, Gong MC, Lemichez E, Boquet P, Somlyo AV, Somlyo AP. Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B. Mol Biol Cell 8: 2437-2447, 1997.
    • (1997) Mol Biol Cell , vol.8 , pp. 2437-2447
    • Fujihara, H.1    Walker, L.A.2    Gong, M.C.3    Lemichez, E.4    Boquet, P.5    Somlyo, A.V.6    Somlyo, A.P.7
  • 16
    • 53449100875 scopus 로고    scopus 로고
    • Actin cytoskeletal dynamics in smooth muscle: A new paradigm for the regulation of smooth muscle contraction
    • Gunst SJ, Zhang W. Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. Am J Physiol Cell Physiol 295: C576-C587, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Gunst, S.J.1    Zhang, W.2
  • 17
    • 27844604200 scopus 로고    scopus 로고
    • Rho GTPases and the control of cell behaviour
    • Hall A. Rho GTPases and the control of cell behaviour. Biochem Soc Trans 33: 891-895, 2005.
    • (2005) Biochem Soc Trans , vol.33 , pp. 891-895
    • Hall, A.1
  • 19
    • 28944451809 scopus 로고    scopus 로고
    • Molecular aspects of arterial smooth muscle contraction: Focus on Rho
    • Hilgers RH, Webb RC. Molecular aspects of arterial smooth muscle contraction: focus on Rho. Exp Biol Med (Maywood) 230: 829-835, 2005.
    • (2005) Exp Biol Med (Maywood) , vol.230 , pp. 829-835
    • Hilgers, R.H.1    Webb, R.C.2
  • 20
    • 4344621091 scopus 로고    scopus 로고
    • Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium
    • Hirakawa M, Oike M, Karashima Y, Ito Y. Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium. J Physiol 558: 479-488, 2004.
    • (2004) J Physiol , vol.558 , pp. 479-488
    • Hirakawa, M.1    Oike, M.2    Karashima, Y.3    Ito, Y.4
  • 22
    • 0032887392 scopus 로고    scopus 로고
    • Actin reorganization in airway smooth muscle cells involves Gq and Gi-2 activation of Rho
    • Hirshman CA, Emala CW. Actin reorganization in airway smooth muscle cells involves Gq and Gi-2 activation of Rho. Am J Physiol Lung Cell Mol Physiol 277: L653-L661, 1999.
    • (1999) Am J Physiol Lung Cell Mol Physiol , vol.277
    • Hirshman, C.A.1    Emala, C.W.2
  • 27
  • 28
    • 11144237626 scopus 로고    scopus 로고
    • The integrin-linked kinase regulates cell morphology and motility in a Rho-associated kinase-dependent manner
    • Khyrul WAKM, LaLonde DP, Brown MC, Levinson H, Turner CE. The integrin-linked kinase regulates cell morphology and motility in a Rho-associated kinase-dependent manner. J Biol Chem 279: 54131-54139, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 54131-54139
    • Khyrul, W.A.K.M.1    LaLonde, D.P.2    Brown, M.C.3    Levinson, H.4    Turner, C.E.5
  • 29
    • 53449101190 scopus 로고    scopus 로고
    • Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent
    • Kim HR, Gallant C, Leavis PC, Gunst SJ, Morgan KG. Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent. Am J Physiol Cell Physiol 295: C768-C778, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Kim, H.R.1    Gallant, C.2    Leavis, P.C.3    Gunst, S.J.4    Morgan, K.G.5
  • 31
    • 70349614410 scopus 로고    scopus 로고
    • Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction
    • Kogata N, Tribe RM, Fassler R, Way M, Adams RH. Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction. Genes Dev 23: 2278-2283, 2009.
    • (2009) Genes Dev , vol.23 , pp. 2278-2283
    • Kogata, N.1    Tribe, R.M.2    Fassler, R.3    Way, M.4    Adams, R.H.5
  • 32
    • 58149384692 scopus 로고    scopus 로고
    • RhoA/Rho-kinase as a therapeutic target in asthma
    • Kume H. RhoA/Rho-kinase as a therapeutic target in asthma. Curr Med Chem 15: 2876-2885, 2008.
    • (2008) Curr Med Chem , vol.15 , pp. 2876-2885
    • Kume, H.1
  • 33
    • 33846405257 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate causes airway hyper-reactivity by rho-mediated myosin phosphatase inactivation
    • Kume H, Takeda N, Oguma T, Ito S, Kondo M, Ito Y, Shimokata K. Sphingosine 1-phosphate causes airway hyper-reactivity by rho-mediated myosin phosphatase inactivation. J Pharmacol Exp Ther 320: 766-773, 2007.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 766-773
    • Kume, H.1    Takeda, N.2    Oguma, T.3    Ito, S.4    Kondo, M.5    Ito, Y.6    Shimokata, K.7
  • 34
    • 33749647220 scopus 로고    scopus 로고
    • Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli
    • Liu C, Zuo J, Janssen LJ. Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Eur Respir J 28: 703-711, 2006.
    • (2006) Eur Respir J , vol.28 , pp. 703-711
    • Liu, C.1    Zuo, J.2    Janssen, L.J.3
  • 36
    • 0031963672 scopus 로고    scopus 로고
    • Clostridium difficile toxin B inhibits carbachol-induced force and myosin light chain phosphorylation in guinea-pig smooth muscle: Role of Rho proteins
    • Lucius C, Arner A, Steusloff A, Troschka M, Hofmann F, Aktories K, Pfitzer G. Clostridium difficile toxin B inhibits carbachol-induced force and myosin light chain phosphorylation in guinea-pig smooth muscle: role of Rho proteins. J Physiol 506: 83-93, 1998.
    • (1998) J Physiol , vol.506 , pp. 83-93
    • Lucius, C.1    Arner, A.2    Steusloff, A.3    Troschka, M.4    Hofmann, F.5    Aktories, K.6    Pfitzer, G.7
  • 38
    • 0033199069 scopus 로고    scopus 로고
    • Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle
    • Mehta D, Gunst SJ. Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle. J Physiol 519: 829-840, 1999.
    • (1999) J Physiol , vol.519 , pp. 829-840
    • Mehta, D.1    Gunst, S.J.2
  • 39
    • 0033580391 scopus 로고    scopus 로고
    • Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase
    • Murakami H, Iwashita T, Asai N, Iwata Y, Narumiya S, Takahashi M. Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase. Oncogene 18: 1975-1982, 1999.
    • (1999) Oncogene , vol.18 , pp. 1975-1982
    • Murakami, H.1    Iwashita, T.2    Asai, N.3    Iwata, Y.4    Narumiya, S.5    Takahashi, M.6
  • 40
    • 0032485940 scopus 로고    scopus 로고
    • Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk- Associated substrate
    • Needham LK, Rozengurt E. Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk- associated substrate. J Biol Chem 273: 14626-14632, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 14626-14632
    • Needham, L.K.1    Rozengurt, E.2
  • 41
    • 0028980248 scopus 로고
    • Involvement of rho in GTP gamma S-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: Inhibition of phosphatase activity
    • Noda M, Yasuda-Fukazawa C, Moriishi K, Kato T, Okuda T, Kurokawa K, Takuwa Y. Involvement of rho in GTP gamma S-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity. FEBS Lett 367: 246-250, 1995.
    • (1995) FEBS Lett , vol.367 , pp. 246-250
    • Noda, M.1    Yasuda-Fukazawa, C.2    Moriishi, K.3    Kato, T.4    Okuda, T.5    Kurokawa, K.6    Takuwa, Y.7
  • 42
    • 0028350016 scopus 로고
    • Effect of cytochalasin B on intestinal smooth muscle cells
    • Obara K, Yabu H. Effect of cytochalasin B on intestinal smooth muscle cells. Eur J Pharmacol 255: 139-147, 1994.
    • (1994) Eur J Pharmacol , vol.255 , pp. 139-147
    • Obara, K.1    Yabu, H.2
  • 43
    • 21744450576 scopus 로고    scopus 로고
    • Role of the actin cytoskeleton in G-protein-coupled receptor activation of PYK2 and paxillin in vascular smooth muscle
    • Ohanian V, Gatfield K, Ohanian J. Role of the actin cytoskeleton in G-protein-coupled receptor activation of PYK2 and paxillin in vascular smooth muscle. Hypertension 46: 93-99, 2005.
    • (2005) Hypertension , vol.46 , pp. 93-99
    • Ohanian, V.1    Gatfield, K.2    Ohanian, J.3
  • 44
    • 0034602959 scopus 로고    scopus 로고
    • Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
    • Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem 275: 3577-3582, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 3577-3582
    • Ohashi, K.1    Nagata, K.2    Maekawa, M.3    Ishizaki, T.4    Narumiya, S.5    Mizuno, K.6
  • 45
    • 0029831696 scopus 로고    scopus 로고
    • Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle
    • Otto B, Steusloff A, Just I, Aktories K, Pfitzer G. Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle. J Physiol 496: 317-329, 1996.
    • (1996) J Physiol , vol.496 , pp. 317-329
    • Otto, B.1    Steusloff, A.2    Just, I.3    Aktories, K.4    Pfitzer, G.5
  • 46
  • 47
    • 73949121819 scopus 로고    scopus 로고
    • Regulation of smooth muscle contraction by small GTPases
    • Puetz S, Lubomirov LT, Pfitzer G. Regulation of smooth muscle contraction by small GTPases. Physiology (Bethesda) 24: 342-356, 2009.
    • (2009) Physiology (Bethesda) , vol.24 , pp. 342-356
    • Puetz, S.1    Lubomirov, L.T.2    Pfitzer, G.3
  • 48
    • 0027944638 scopus 로고
    • Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin
    • Rankin S, Morii N, Narumiya S, Rozengurt E. Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin. FEBS Lett 354: 315-319, 1994.
    • (1994) FEBS Lett , vol.354 , pp. 315-319
    • Rankin, S.1    Morii, N.2    Narumiya, S.3    Rozengurt, E.4
  • 49
    • 0029886579 scopus 로고    scopus 로고
    • Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus
    • Saito SY, Hori M, Ozaki H, Karaki H. Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus. J Smooth Muscle Res 32: 51-60, 1996.
    • (1996) J Smooth Muscle Res , vol.32 , pp. 51-60
    • Saito, S.Y.1    Hori, M.2    Ozaki, H.3    Karaki, H.4
  • 50
    • 21844442150 scopus 로고    scopus 로고
    • Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: The roles of Rho-kinase and protein kinase C
    • DOI 10.1139/y05-022
    • Sakai H, Hirano T, Takeyama H, Chiba Y, Misawa M. Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: the roles of Rho-kinase and protein kinase C. Can J Physiol Pharmacol 83: 375-381, 2005. (Pubitemid 40961267)
    • (2005) Canadian Journal of Physiology and Pharmacology , vol.83 , Issue.4 , pp. 375-381
    • Sakai, H.1    Hirano, T.2    Takeyama, H.3    Chiba, Y.4    Misawa, M.5
  • 51
    • 0037227358 scopus 로고    scopus 로고
    • Inhibitors of actin filament polymerisation attenuate force but not global intracellular calcium in isolated pressurised resistance arteries
    • Shaw L, Ahmed S, Austin C, Taggart MJ. Inhibitors of actin filament polymerisation attenuate force but not global intracellular calcium in isolated pressurised resistance arteries. J Vasc Res 40: 1-10, 2003.
    • (2003) J Vasc Res , vol.40 , pp. 1-10
    • Shaw, L.1    Ahmed, S.2    Austin, C.3    Taggart, M.J.4
  • 52
    • 0037383931 scopus 로고    scopus 로고
    • Mechanical stress increases RhoA activation in airway smooth muscle cells
    • Smith PG, Roy C, Zhang YN, Chauduri S. Mechanical stress increases RhoA activation in airway smooth muscle cells. Am J Respir Cell Mol Biol 28: 436-442, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 436-442
    • Smith, P.G.1    Roy, C.2    Zhang, Y.N.3    Chauduri, S.4
  • 53
    • 0141751697 scopus 로고    scopus 로고
    • 2+ sensitivity of smooth muscle and non-muscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • 2+ sensitivity of smooth muscle and non-muscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1358, 2003.
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 54
    • 0033603052 scopus 로고    scopus 로고
    • M3 muscarinic acetylcholine receptors regulate cytoplasmic myosin by a process involving RhoA and requiring conventional protein kinase C isoforms
    • Strassheim D, May LG, Varker KA, Puhl HL, Phelps SH, Porter RA, Aronstam RS, Noti JD, Williams CL. M3 muscarinic acetylcholine receptors regulate cytoplasmic myosin by a process involving RhoA and requiring conventional protein kinase C isoforms. J Biol Chem 274: 18675-18685, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 18675-18685
    • Strassheim, D.1    May, L.G.2    Varker, K.A.3    Puhl, H.L.4    Phelps, S.H.5    Porter, R.A.6    Aronstam, R.S.7    Noti, J.D.8    Williams, C.L.9
  • 56
    • 0034998560 scopus 로고    scopus 로고
    • Depletion of focal adhesion kinase by antisense depresses contractile activation of smooth muscle
    • Tang DD, Gunst SJ. Depletion of focal adhesion kinase by antisense depresses contractile activation of smooth muscle. Am J Physiol Cell Physiol 280: C874-C883, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Tang, D.D.1    Gunst, S.J.2
  • 57
    • 0344896781 scopus 로고    scopus 로고
    • Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development
    • Tang DD, Turner CE, Gunst SJ. Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development. J Physiol 553: 21-35, 2003.
    • (2003) J Physiol , vol.553 , pp. 21-35
    • Tang, D.D.1    Turner, C.E.2    Gunst, S.J.3
  • 58
    • 20744455807 scopus 로고    scopus 로고
    • The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle
    • Tang DD, Zhang W, Gunst SJ. The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle. J Biol Chem 280: 23380-23389, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 23380-23389
    • Tang, D.D.1    Zhang, W.2    Gunst, S.J.3
  • 59
    • 10644285520 scopus 로고    scopus 로고
    • The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle
    • Tang DD, Gunst SJ. The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle. J Biol Chem 279: 51722-51728, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 51722-51728
    • Tang, D.D.1    Gunst, S.J.2
  • 60
    • 0031807422 scopus 로고    scopus 로고
    • Carbachol-induced actin reorganization involves Gi activation of Rho in human airway smooth muscle cells
    • Togashi H, Emala CW, Hall IP, Hirshman CA. Carbachol-induced actin reorganization involves Gi activation of Rho in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 274: L803-L809, 1998.
    • (1998) Am J Physiol Lung Cell Mol Physiol , vol.274
    • Togashi, H.1    Emala, C.W.2    Hall, I.P.3    Hirshman, C.A.4
  • 62
    • 0030590084 scopus 로고    scopus 로고
    • Involvement of rho p21 in cyclic strain-induced tyrosine phosphorylation of focal adhesion kinase (pp125FAK), morphological changes and migration of endothelial cells
    • Yano Y, Saito Y, Narumiya S, Sumpio BE. Involvement of rho p21 in cyclic strain-induced tyrosine phosphorylation of focal adhesion kinase (pp125FAK), morphological changes and migration of endothelial cells. Biochem Biophys Res Commun 224: 508-515, 1996.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 508-515
    • Yano, Y.1    Saito, Y.2    Narumiya, S.3    Sumpio, B.E.4
  • 63
    • 37849011198 scopus 로고    scopus 로고
    • Interactions of airway smooth muscle cells with their tissue matrix: Implications for contraction
    • Zhang W, Gunst SJ. Interactions of airway smooth muscle cells with their tissue matrix: implications for contraction. Proc Am Thorac Soc 5: 32-39, 2008.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 32-39
    • Zhang, W.1    Gunst, S.J.2
  • 64
    • 17644379396 scopus 로고    scopus 로고
    • Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle
    • Zhang W, Wu Y, Du L, Tang DD, Gunst SJ. Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle. Am J Physiol Cell Physiol 288: C1145-C1160, 2005.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Zhang, W.1    Wu, Y.2    Du, L.3    Tang, D.D.4    Gunst, S.J.5
  • 65
    • 36348994455 scopus 로고    scopus 로고
    • Integrin-linked kinase (ILK) regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle
    • Zhang W, Wu Y, Wu C, Gunst SJ. Integrin-linked kinase (ILK) regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle. J Biol Chem 282: 34568-34580, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 34568-34580
    • Zhang, W.1    Wu, Y.2    Wu, C.3    Gunst, S.J.4
  • 66
    • 33645808902 scopus 로고    scopus 로고
    • Dynamic association between alpha-actinin and beta-integrin regulates contraction of canine tracheal smooth muscle
    • Zhang WW, Gunst SJ. Dynamic association between alpha-actinin and beta-integrin regulates contraction of canine tracheal smooth muscle. J Physiol (London) 572: 659-676, 2006.
    • (2006) J Physiol (London) , vol.572 , pp. 659-676
    • Zhang, W.W.1    Gunst, S.J.2
  • 67
    • 61349110133 scopus 로고    scopus 로고
    • ADF/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle
    • Zhao R, Du L, Huang Y, Wu Y, Gunst SJ. ADF/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle. J Biol Chem 283: 36522-36531, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 36522-36531
    • Zhao, R.1    Du, L.2    Huang, Y.3    Wu, Y.4    Gunst, S.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.