Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo

Blood

Volumn 116, Issue 1, 2010, Pages 81-84

  Sengupta, Amitava ^a   Arnett, Jorden ^a   Dunn, Susan ^b   Williams, David A ^c   Cancelas, Jose A ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; RAC2 PROTEIN; TRANSCRIPTION FACTOR TAL1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ONCOPROTEIN; RAC PROTEIN; TAL1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CANCER STEM CELL; CELL ADHESION; CELL HOMING; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; IN VIVO STUDY; LEUKEMIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CELL MOTION; FEMALE; FLOW CYTOMETRY; GENETICS; KAPLAN MEIER METHOD; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; FUSION PROTEINS, BCR-ABL; HEMATOPOIETIC STEM CELLS; KAPLAN-MEIERS ESTIMATE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS; RAC GTP-BINDING PROTEINS;

EID: 77955879135     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-10-247437     Document Type: Article

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