Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolism

Molecular Microbiology

Volumn 62, Issue 4, 2006, Pages 1048-1063

  Battesti, Aurélia ^a   Bouveret, Emmanuelle ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; BACTERIAL PROTEIN; HYBRID PROTEIN; MUTANT PROTEIN; SPOT PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ESCHERICHIA COLI; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; NONHUMAN; PLASMID; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRESS;

ACYL CARRIER PROTEIN; ESCHERICHIA COLI K12; ESCHERICHIA COLI PROTEINS; FATTY ACIDS; GUANINE NUCLEOTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PYROPHOSPHATASES; TWO-HYBRID SYSTEM TECHNIQUES;

ESCHERICHIA COLI;

EID: 33750479525     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05442.x     Document Type: Article

References (49)

1. Aravind, L., and Koonin, E.V. (1998) The HD domain defines a new superfamily of metal-dependent phosphohydrolases. Trends Biochem Sci 23: 469-472.
2. Avarbock, D., Salem, J., Li, L.S., Wang, Z.M., and Rubin, H. (1999) Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis. Gene 233: 261-269.
3. Bachmann, B.J. (1987) Derivations and genotypes of some mutant derivatives of Escherichia coli K-12. In Escherichia coli and Salmonella typhimurium. Neidhardt, F.C. (ed.). Washington, DC: American Society for Microbiology Press, pp. 1191-1219.
4. Brent, R., and Finley, R.L., Jr (1997) Understanding gene and allele function with two-hybrid methods. Annu Rev Genet 31: 663-704.
5. Butland, G., Peregrin-Alvarez, J.M., Li, J., Yang, W., Yang, X., Canadien, V., et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433: 531-537.
6. Casadaban, M.J. (1976) Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. J Mol Biol 104: 541-555.
7. Cashel, M. (1994) Detection of (p)ppGpp accumulation patterns in Escherichia coli mutants. In Methods in Molecular Genetics, Vol. 3. Adolph, K.W. (ed.). New York: Academic Press, pp. 341-356.
8. Cashel, M., Gentry, D., Hernandez, V.J., and Vinella, D. (1996) The stringent response. In Escherichia coli and Salmonella typhimurium. Neidhardt, F. (ed.). Washington, DC: American Society for Microbiology Press, pp. 1458-1496.
9. Chipman, D.M., and Shaanan, B. (2001) The ACT domain family. Curr Opin Struct Biol 11: 694-700.
10. De Lay, N.R., and Cronan, J.E. (2006) Gene-specific random mutagenesis of Escherichia coli in vivo: isolation of temperature-sensitive mutations in the acyl carrier protein of fatty acid synthesis. J Bacteriol 188: 287-296.
11. DiRusso, C.C., and Nystrom, T. (1998) The fats of Escherichia coli during infancy and old age: regulation by global regulators, alarmones and lipid intermediates. Mol Microbiol 27: 1-8.
12. Foti, J.J., Schienda, J., Sutera, V.A., Jr, and Lovett, S.T. (2005) A bacterial G protein-mediated response to replication arrest. Mol Cell 17: 549-560.
13. Gavin, A.C., Bosche, M., Krause, R., Grandi, P., Marzioch, M., Bauer, A., et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415: 141-147.
14. Gentry, D.R., and Cashel, M. (1996) Mutational analysis of the Escherichia coli spoT gene identifies distinct but overlapping regions involved in ppGpp synthesis and degradation. Mol Microbiol 19: 1373-1384.
15. Gentry, D.R., Hernandez, V.J., Nguyen, L.H., Jensen, D.B., and Cashel, M. (1993) Synthesis of the stationary-phase sigma factor sigma s is positively regulated by ppGpp. J Bacteriol 175: 7982-7989.
16. Godfrey, H.P., Bugrysheva, J.V., and Cabello, F.C. (2002) The role of the stringent response in the pathogenesis of bacterial infections. Trends Microbiol 10: 349-351.
17. Gong, L., Takayama, K., and Kjelleberg, S. (2002) Role of spoT-dependent ppGpp accumulation in the survival of light-exposed starved bacteria. Microbiology 148: 559-570.
18. Gropp, M., Strausz, Y., Gross, M., and Glaser, G. (2001) Regulation of Escherichia coli RelA requires oligomerization of the C-terminal domain. J Bacteriol 183: 570-579.
19. Gully, D., and Bouveret, E. (2006) A protein network for phospholipid synthesis uncovered by a variant of the tandem affinity purification method in Escherichia coli. Proteomics 6: 282-293.
20. Gully, D., Moinier, D., Loiseau, L., and Bouveret, E. (2003) New partners of acyl carrier protein detected in Escherichia coli by tandem affinity purification. FEBS Lett 548: 90-96.
21. Heath, R.J., Jackowski, S., and Rock, C.O. (1994) Guanosine tetraphosphate inhibition of fatty acid and phospholipid synthesis in Escherichia coli is relieved by overexpression of glycerol-3-phosphate acyltransferase (plsB). J Biol Chem 269: 26584-26590.
22. Hogg, T., Mechold, U., Malke, H., Cashel, M., and Hilgenfeld, R. (2004) Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response. Cell 117: 57-68.
23. Johansson, J., Balsalobre, C., Wang, S.Y., Urbonaviciene, J., Jin, D.J., Sonden, B., and Uhlin, B.E. (2000) Nucleoid proteins stimulate stringently controlled bacterial promoters: a link between the cAMP-CRP and the (p)ppGpp regulons in Escherichia coli. Cell 102: 475-485.
24. Karimova, G., Pidoux, J., Ullmann, A., and Ladant, D. (1998) A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc Natl Acad Sci USA 95: 5752-5756.
25. Kim, Y., and Prestegard, J.H. (1989) A dynamic model for the structure of acyl carrier protein in solution. Biochemistry 28: 8792-8797.
26. Link, A.J., Phillips, D., and Church, G.M. (1997) Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization. J Bacteriol 179: 6228-6237.
27. McDougald, D., Gong, L., Srinivasan, S., Hild, E., Thompson, L., Takayama, K., et al. (2002) Defences against oxidative stress during starvation in bacteria. Antonie Van Leeuwenhoek 81: 3-13.
28. Magnusson, L.U., Farewell, A., and Nystrom, T. (2005) ppGpp: a global regulator in Escherichia coli. Trends Microbiol 13: 236-242.
29. Mechold, U., Cashel, M., Steiner, K., Gentry, D., and Malke, H. (1996) Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis. J Bacteriol 178: 1401-1411.
30. Mechold, U., Murphy, H., Brown, L., and Cashel, M. (2002) Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis. J Bacteriol 184: 2878-2888.
31. Miller, J.H. (1992) A Short Course in Bacterial Genetics: A Laboratory Manual and Handbook for Escherichia coli and Related Bacteria. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
32. Mittenhuber, G. (2001) Comparative genomics and evolution of genes encoding bacterial (p)ppGpp synthetases/hydrolases (the Rel, RelA and SpoT proteins). J Mol Microbiol Biotechnol 3: 585-600.
33. Murray, K.D., and Bremer, H. (1996) Control of spoT-dependent ppGpp synthesis and degradation in Escherichia coli. J Mol Biol 259: 41-57.
34. Pedersen, F.S., and Kjeldgaard, N.O. (1977) Analysis of the relA gene product of Escherichia coli. Eur J Biochem 76: 91-97.
35. Podkovyrov, S.M., and Larson, T.J. (1996) Identification of promoter and stringent regulation of transcription of the fabH, fabD and fabG genes encoding fatty acid biosynthetic enzymes of Escherichia coli. Nucleic Acids Res 24: 1747-1752.
36. Rock, C.O., and Cronan, J.E. (1996) Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesis. Biochim Biophys Acta 1302: 1-16.
37. Rudd, K.E., Bochner, B.R., Cashel, M., and Roth, J.R. (1985) Mutations in the spoT gene of Salmonella typhimurium: effects on his operon expression. J Bacteriol 163: 534-542.
38. Sankaranarayanan, R., Dock-Bregeon, A.C., Romby, P., Caillet, J., Springer, M., Rees, B., et al. (1999) The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site. Cell 97: 371-381.
39. Sarubbi, E., Rudd, K.E., and Cashel, M. (1988) Basal ppGpp level adjustment shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coli. Mol Gen Genet 213: 214-222.
40. Sarubbi, E., Rudd, K.E., Xiao, H., Ikehara, K., Kalman, M., and Cashel, M. (1989) Characterization of the spoT gene of Escherichia coli. J Biol Chem 264: 15074-15082.
41. Sato, A., Kobayashi, G., Hayashi, H., Yoshida, H., Wada, A., Maeda, M., et al. (2005) The GTP binding protein Obg homolog ObgE is involved in ribosome maturation. Genes Cells 10: 393-408.
42. Seyfzadeh, M., Keener, J., and Nomura, M. (1993) spoT-dependent accumulation of guanosine tetraphosphate in response to fatty acid starvation in Escherichia coli. Proc Natl Acad Sci USA 90: 11004-11008.
43. Tetu, C., Dassa, E., and Boquet, P.L. (1980) The energy-dependent degradation of guanosine 5′-diphosphate 3′-diphosphate in Escherichia coli. Lack of correlation with ATP levels in vivo and role of the transmembrane proton gradient. Eur J Biochem 103: 117-124.
44. Uzan, M., and Danchin, A. (1978) Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA- mutants. Mol Gen Genet 165: 21-30.
45. Vinella, D., Albrecht, C., Cashel, M., and D'Ari, R. (2005) Iron limitation induces SpoT-dependent accumulation of ppGpp in Escherichia coli. Mol Microbiol 56: 958-970.
46. Wendrich, T.M., Blaha, G., Wilson, D.N., Marahiel, M.A., and Nierhaus, K.H. (2002) Dissection of the mechanism for the stringent factor RelA. Mol Cell 10: 779-788.
47. Wolf, Y.I., Aravind, L., Grishin, N.V., and Koonin, E.V. (1999) Evolution of aminoacyl-tRNA synthetases - analysis of unique domain architectures and phylogenetic trees reveals a complex history of horizontal gene transfer events. Genome Res 9: 689-710.
48. Wout, P., Pu, K., Sullivan, S.M., Reese, V., Zhou, S., Lin, B., and Maddock, J.R. (2004) The Escherichia coli GTPase CgtAE cofractionates with the 50S ribosomal subunit and interacts with SpoT, a ppGpp synthetase/hydrolase. J Bacteriol 186: 5249-5257.
49. Xiao, H., Kalman, M., Ikehara, K., Zemel, S., Glaser, G., and Cashel, M. (1991) Residual guanosine 3′,5′-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations. J Biol Chem 266: 5980-5990.