Association between plasma ghrelin and motilin levels during MMC cycle in conscious dogs

Regulatory Peptides

Volumn 164, Issue 2-3, 2010, Pages 78-82

  Zietlow, Aaron ^a   Nakajima, Hitoshi ^a   Taniguchi, Hiroshi ^a   Ludwig, Kirk ^a   Takahashi, Toku ^a  

^a CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Feeding activity; Hunger contractions; Phase III contractions

Indexed keywords

GHRELIN; MOTILIN;

ANIMAL EXPERIMENT; ARTICLE; CONSCIOUSNESS; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; HORMONE ACTION; HORMONE BLOOD LEVEL; HUNGER; INTESTINE MUSCLE; MUSCLE ACTION POTENTIAL; MUSCLE INNERVATION; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; STOMACH MUSCLE;

ANIMALS; CONSCIOUSNESS; DOGS; FEMALE; GHRELIN; MOTILIN; MYOELECTRIC COMPLEX, MIGRATING; RADIOIMMUNOASSAY;

CANIS FAMILIARIS; RODENTIA;

EID: 77955841124     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2010.05.006     Document Type: Article

References (47)

1. Vantrappen G., Janssens J., Hellemans J., Ghoos Y. The interdigestive motor complex of normal subjects and patients with bacterial overgrowth of the small intestine. J Clin Invest 1977, 59:1158-1166.
2. Itoh Z., Honda R., Hiwatashi K., Takeuchi S., Aizawa I., Takayanagi R., Couch E.F. Motilin-induced mechanical activity in the canine alimentary tract. Scand J Gastroenterol Suppl 1976, 39:93-110.
3. Hall K.E., Greenberg G.R., El-Sharkawy T.Y., Diamant N.E. Vagal control of migrating motor complex-related peaks in canine plasma motilin, pancreatic polypeptide, and gastrin. Can J Physiol Pharmacol 1983, 61:1289-1298.
4. Vantrappen G., Janssens J., Peeters T.L., Bloom S.R., Christofides N.D., Hellemans J. Motilin and the interdigestive migrating motor complex in man. Dig Dis Sci 1979, 24:497-500.
5. Janssens J., Vantrappen G., Peeters T.L. The activity front of the migrating motor complex of the human stomach but not of the small intestine is motilin-dependent. Regul Pept 1983, 6:363-369.
6. Wingate D.L., Ruppin H., Green W.E., Thompson H.H., Domschke W., Wunsch E., Demling L., Ritchie H.D. Motilin-induced electrical activity in the canine gastrointestinal tract. Scand J Gastroenterol Suppl 1976, 39:111-118.
7. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
8. Fujino K., Inui A., Asakawa A., Kihara N., Fujimura M., Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol 2003, 550:227-240.
9. Ariga H., Tsukamoto K., Chen C., Mantyh C., Pappas T.N., Takahashi T. Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach. Neurogastroenterol Motil 2007, 19:675-680.
10. Zheng J., Ariga H., Taniguchi H., Ludwig K., Takahashi T. Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice. Neurogastroenterol Motil 2009, 21:78-84.
11. Ohno T., Kamiyama Y., Aihara R., Nakabayashi T., Mochiki E., Asao T., Kuwano H. Ghrelin does not stimulate gastrointestinal motility and gastric emptying: an experimental study of conscious dogs. Neurogastroenterol Motil 2006, 18:129-135.
12. Depoortere I., De Winter B., Thijs T., De Man J., Pelckmans P., Peeters T. Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro. Eur J Pharmacol 2005, 515:160-168.
13. Tatewaki M., Harris M., Uemura K., Ueno T., Hoshino E., Shiotani A., Pappas T.N., Takahashi T. Dual effects of acupuncture on gastric motility in conscious rats. Am J Physiol Regul Integr Comp Physiol 2003, 285:R862-R872.
14. Ariga H., Imai K., Chen C., Mantyh C., Pappas T.N., Takahashi T. Fixed feeding potentiates interdigestive gastric motor activity in rats: importance of eating habits for maintaining interdigestive MMC. Am J Physiol Gastrointest Liver Physiol 2008, 294:G655-G659.
15. Taniguchi H., Ariga H., Zheng J., Ludwig K., Mantyh C., Pappas T.N., Takahashi T. Endogenous ghrelin and 5-HT regulate interdigestive gastrointestinal contractions in conscious rats. Am J Physiol Gastrointest Liver Physiol 2008, 295:G403-G411.
16. Chen C.Y., Inui A., Asakawa A., Fujino K., Kato I., Chen C.C., Ueno N., Fujimiya M. Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats. Gastroenterology 2005, 129:8-25.
17. Toshinai K., Date Y., Murakami N., Shimada M., Mondal M.S., Shimbara T., Guan J.L., Wang Q.P., Funahashi H., Sakurai T., Shioda S., Matsukura S., Kangawa K., Nakazato M. Ghrelin-induced food intake is mediated via the orexin pathway. Endocrinology 2003, 144:1506-1512.
18. Toshinai K., Mondal M.S., Nakazato M., Date Y., Murakami N., Kojima M., Kangawa K., Matsukura S. Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochem Biophys Res Commun 2001, 281:1220-1225.
19. Hashimoto H., Fujihara H., Kawasaki M., Saito T., Shibata M., Otsubo H., Takei Y., Ueta Y. Centrally and peripherally administered ghrelin potently inhibits water intake in rats. Endocrinology 2007, 148:1638-1647.
20. Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taheri S., Kennedy A.R., Roberts G.H., Morgan D.G., Ghatei M.A., Bloom S.R. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000, 141:4325-4328.
21. Wren A.M., Small C.J., Abbott C.R., Dhillo W.S., Seal L.J., Cohen M.A., Batterham R.L., Taheri S., Stanley S.A., Ghatei M.A., Bloom S.R. Ghrelin causes hyperphagia and obesity in rats. Diabetes 2001, 50:2540-2547.
22. Yin J., Chen J. Inhibitory effects of gastric electrical stimulation on ghrelin-induced excitatory effects on gastric motility and food intake in dogs. Scand J Gastroenterol 2006, 41:903-909.
23. Akamizu T., Iwakura H., Ariyasu H., Hosoda H., Murayama T., Yokode M., Teramukai S., Seno H., Chiba T., Noma S., Nakai Y., Fukunaga M., Nakai Y., Kangawa K., Team FDCS Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite. Eur J Endocrinol 2008, 158:491-498.
24. Akamizu T., Takaya K., Irako T., Hosoda H., Teramukai S., Matsuyama A., Tada H., Miura K., Shimizu A., Fukushima M., Yokode M., Tanaka K., Kangawa K. Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects. Eur J Endocrinol 2004, 150:447-455.
25. Wren A.M., Seal L.J., Cohen M.A., Brynes A.E., Frost G.S., Murphy K.G., Dhillo W.S., Ghatei M.A., Bloom S.R. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 2001, 86:5992.
26. Natalucci G., Riedl S., Gleiss A., Zidek T., Frisch H. Spontaneous 24-h ghrelin secretion pattern in fasting subjects: maintenance of a meal-related pattern. Eur J Endocrinol 2005, 152:845-850.
27. Ang D., Nicolai H., Vos R., Berghe P., Siflim D., Depoortere I., Peeters T., Janssens J., Tack J. Gastic phase 3 is a hunger signal in the interdigestive state in man. Gastroenterology 2008, 134:A314.
28. Ueno T., Uemura K., Harris M.B., Pappas T.N., Takahashi T. Role of vagus nerve in postprandial antropyloric coordination in conscious dogs. Am J Physiol Gastrointest Liver Physiol 2005, 288:G487-G495.
29. Nakajima H., Mochiki E., Zietlow A., Ludwig K., Takahashi T. Mechanism of interdigestive migrating motor complex in conscious dogs. J Gastroenterol 2010, 45:506-514.
30. Cani P.D., Montoya M.L., Neyrinck A.M., Delzenne N.M., Lambert D.M. Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide. Br J Nutr 2004, 92:757-761.
31. Ariyasu H., Takaya K., Hosoda H., Iwakura H., Ebihara K., Mori K., Ogawa Y., Hosoda K., Akamizu T., Kojima M., Kangawa K., Nakao K. Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology 2002, 143:3341-3350.
32. Abizaid A., Liu Z.W., Andrews Z.B., Shanabrough M., Borok E., Elsworth J.D., Roth R.H., Sleeman M.W., Picciotto M.R., Tschop M.H., Gao X.B., Horvath T.L. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J Clin Invest 2006, 116:3229-3239.
33. Ariyasu H., Takaya K., Tagami T., Ogawa Y., Hosoda K., Akamizu T., Suda M., Koh T., Natsui K., Toyooka S., Shirakami G., Usui T., Shimatsu A., Doi K., Hosoda H., Kojima M., Kangawa K., Nakao K. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 2001, 86:4753-4758.
34. Wang Y., Dong L., Cheng Y., Zhao P. Effects of ghrelin on feeding regulation and interdigestive migrating complex in rats. Scand J Gastroenterol 2007, 42:447-453.
35. Shaw A.M., Irani B.G., Moore M.C., Haskell-Luevano C., Millard W.J. Ghrelin-induced food intake and growth hormone secretion are altered in melanocortin 3 and 4 receptor knockout mice. Peptides 2005, 26:1720-1727.
36. Asakawa A., Inui A., Kaga T., Katsuura G., Fujimiya M., Fujino M.A., Kasuga M. Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut 2003, 52:947-952.
37. Banks W.A., Tschop M., Robinson S.M., Heiman M.L. Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J Pharmacol Exp Ther 2002, 302:822-827.
38. Asakawa A., Inui A., Kaga T., Yuzuriha H., Nagata T., Ueno N., Makino S., Fujimiya M., Niijima A., Fujino M.A., Kasuga M. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 2001, 120:337-345.
39. Poitras P., Peeters T.L. Motilin. Curr Opin Endocrinol Diabetes Obes 2008, 15:54-57.
40. Lemoyne M., Wassef R., Tasse D., Trudel L., Poitras P. Motilin and the vagus in dogs. Can J Physiol Pharmacol 1984, 62:1092-1096.
41. Itoh Z. Motilin and clinical application. Peptides 1997, 18:593-608.
42. Luiking Y.C., Akkermans L.M., Peeters T.L., Cnossen P.J., Nieuwenhuijs V.B., Vanberge-Henegouwen G.P. Effects of motilin on human interdigestive gastrointestinal and gallbladder motility, and involvement of 5HT3 receptors. Neurogastroenterol Motil 2002, 14:151-159.
43. Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
44. Maier C., Schaller G., Buranyi B., Nowotny P., Geyer G., Wolzt M., Luger A. The cholinergic system controls ghrelin release and ghrelin-induced growth hormone release in humans. J Clin Endocrinol Metab 2004, 89:4729-4733.
45. Simonian H.P., Kresge K.M., Boden G.H., Parkman H.P. Differential effects of sham feeding and meal ingestion on ghrelin and pancreatic polypeptide levels: evidence for vagal efferent stimulation mediating ghrelin release. Neurogastroenterol Motil 2005, 17:348-354.
46. Hosoda H., Kangawa K. The autonomic nervous system regulates gastric ghrelin secretion in rats. Regul Pept 2008, 146:12-18.
47. Itoh Z., Aizawa I., Sekiguchi T. The interdigestive migrating complex and its significance in man. Clin Gastroenterol 1982, 11:497-521.