Low-dose ionizing radiation effects on differentiation of HL-60 cells

Central European Journal of Biology

Volumn 5, Issue 5, 2010, Pages 600-612

  Savickiene, Jurate ^a   Treigyte, Grazina ^a   Aleksandraviciene, Ceslava ^b   Navakauskiene, Ruta ^a,c  

^a VILNIUS UNIVERSITY   (Lithuania)

^b Laboratory of Molecular Oncology   (Lithuania)

^c VILNIUS GEDIMINAS TECHNICAL UNIVERSITY   (Lithuania)

Author keywords

Apoptosis; Granulocytic differentiation; HL 60 cells; Low dose radiation

Indexed keywords

EID: 77955837272     PISSN: 1895104X     EISSN: 16443632     Source Type: Journal    
DOI: 10.2478/s11535-010-0085-2     Document Type: Article

References (68)

1. Feinendegen L. E. Evidence for beneficial low level radiation effects and radiation hormesis, Br. J. Radiol., 2005, 78, 3-7.
2. Feinendegen L. E., Loken M. K., Booz J., Muehlensiepen H., Sondhaus C. A., Bond V. P. Cellular mechanisms of protection and repair induced by radiation exposure and their consequences for cell system responses, Stem Cells, 1995, 13, 7-20.
3. Feinendegen L. E. The role of adaptive responses following exposure to ionizing radiation, Hum. Exp. Toxicol., 1999, 18, 426-432.
4. Shadley J. D., Wiencke J. K. Induction of the adaptive response by X-rays is dependent on radiation intensity, Int. J. Radiat. Biol., 1989, 56, 107-118.
5. Wolff S. The adaptive response in radiobiology evolving insights and implications, Environ. Health Perspect., 1998, 106, 277-283.
6. Park S. H., Lee Y., Jeong K., Yoo S. Y., Cho C. K., Lee Y. S. Different induction of adaptive response to ionizing radiation in normal and neoplastic cells, Cell. Biol. Toxicol., 1999, 15, 111-119.
7. Suzuki K., Komada S., Watanabe M. Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells, Cancer Res., 2001, 61, 5396-5401.
8. Kim J. H., Hyun S. J., Yoon M. Y., Ji Y. H., Cho C. K., Yoo S. Y. Pretreatment of low-dose radiation reduces radiation-induced apoptosis in mouse lymphoma (EL4) cells, Arch. Pharmacol. Res., 1997, 20, 212-217.
9. Chen Z., Sakai K. Enhancement of radiation-induced apoptosis by preirradiation with low-dose X-rays in human leukemia MOLT-4 cells, J. Radiat. Res., 2004, 45, 239-243.
10. Carter S., Auer K. L., Readon D. B., Birrel M., Fisher P. B., Valerie K., et al. Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells, Oncogene, 1998, 16, 2787-2796.
11. Milne D. M., Campbell D. G., Caudwell F. B., Meek D. W. Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases, J. Biol. Chem., 1995, 269, 9253-9260.
12. Kasid U., Suy S., Dent P., Ray S., Whiteside T. M., Strugill T. W. Activation of Raf by ionizing radiation, Nature, 1996, 382, 813-816.
13. Verheij M., Ruiter G. A., Zerp C. F., van Blitterswijk W. J., Fuks Z., Haimovtz-Friedman A., et al. The role of the stress-activated kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis, Radiother. Oncol., 1998, 17, 225-232.
14. Prasad A. V., Mohan N., Chandrasekar B., Meltz M. L. Induction of transcription of "immediate early genes" by low-dose ionizing radiation, 1995, 143, 263-272.
15. Bishay K., Ory K., Labeau J., Levalois C., Olivier C., Chevillard S. DNA-damage-related gene expression as biomarkers to assess cellular response after gamma irradiation of human lymphoblastoid cell line, Oncogene, 2000, 19, 916-923.
16. Loree J., Koturbash I, Kutanzi K., Baker M., Pogribny I., Kovalchuk O. Radiation-induced molecular changes in rat mammary tissue: possible implications for radiation-induced carcinogenesis, Int. J. Radiat. Biol., 2006, 82, 805-815.
17. Suzuki K., Kodama S., Watanabe M. Low-dose radiation effects and intracellular signaling pathways, Yakugaku Zasshi, 2006, 126, 859-867.
18. Amundson S. A., Lee R. A., Koch-Paiz C. A., Bittner M. L., Meltzer P., Trent J. M., et al. Differential responses of stress genes to low dose-rate gamma irradiation, Mol. Cancer Res., 2003, 1, 445-452.
19. Chen S. L., Cai L., Li X. K., Liu S. Z. Low-dose whole body irradiation induces alterations of protein expression in mouse thymocytes, Toxicol. Lett., 1999, 105, 141-152.
20. Chen S. L., Cai L., Meng Q. Y., Xu S., Wan H., Liu S. Z. Low dose Whole-Body irradiation (LD-WBI) changes protein expression of mouse thymocytes: effect of a LD-WBI-enhanced protein RIP10 on cell proliferation and spontaneous or radiation-induced thymocyte apoptosis, Toxicol. Sci., 2000, 55, 97-106.
21. Stulik J., Koupilova K., Hernychova L., Macela A., Blacha V., Baaske C., et al. Modulation of signal transduction pathways and global protein composition of macrophages by ionizing radiation, Electrophoresis, 1999, 20, 962-968.
22. Kastner P., Chan S. Function of RARα during the maturation of neutrophils, Oncogene, 2001, 20, 7178-7185.
23. Collins S. The HL-60 promyelocytic leukemia cell line: Proliferation, differentiation and cellular oncogene expression, Blood, 1987, 70, 123-144.
24. Drexler H. G., Quentmeir H., Mac Leod R. A., Uphoff C. C., Hu Z. B. Leukemia cell lines: in vitro models for the study of acute promyelocytic leukemia, Leukem. Res., 1995, 19, 681-691.
25. Slack J. I., Rusiniak M. A. Current issues in the management of acute promyelocytic leukemia, Ann. Hematol., 2000, 79, 227-238.
26. Martin S. J., Bradley J. G., Cotter T. G. HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis, Clin. Exp. Immunol., 1990, 79, 448-453.
27. Collins S. J., Ruscetti F. W., Galagher R. E., Gallo R. C. Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide, J. Exp. Med., 1979, 49, 969-974.
28. Mercille S., Massie B. Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells, Biotechnol. Bioingeneer., 1994, 44, 1140-1154.
29. Watson R. W., Rotstein O. D., Parodo J., Bitar R., Hackam D., Marshall J. C. Granulocytic differentiation of HL-60 cells results in spontaneous apoptosis mediated by increase caspase expression, FEBS Lett., 1997, 412, 603-609.
30. Kuerbitz S. J., Plunkett B. S., Walsh W. V., Kastan M. B. Wilde-type p53 is a cell cycle checkpoint determinant following irradiation, Proc. Natl. Acad. Sci. USA, 1992, 89, 7491-7495.
31. Livingstone L. R., White A., Sprouse J., Livanos E., Jacks T., Tisty T. D. Altered cell cycle arrest and gene amplification potential accompany loss of wilde-type p53, Cell, 1992, 70, 923-935.
32. O'Connor P. M., Jackman J., Jondle D., Bhatia K., Magrath I., Kohn K. W. Role of p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkit's lymphoma cell lines, Cancer Res., 1993, 53, 4776-4780.
33. Han Z., Chatterjee D., He D. M., Early J., Pantazis P., Wyche J. H., et al. Evidence for a G2 checkpoint in p53-independent apoptosis induction by X-irradiation, Mol. Cell Biol., 1995, 15, 5849-5857.
34. Nagy L., Thomazy V. A., Shipley G. L., Fesus L., Lamph W., Heyman R. A, et al. Activation of retinoid X receptors induces apoptosis in HL-60 cell line, Mol. Cell Biol., 1995, 15, 3540-3551.
35. Ohashi M., Iwase W. M., Nagumo M. Changes in susceptibility to Fas-mediated apoptosis during differentiation of HL-60 cells, J. Leuk. Biol., 2000, 67, 374-380.
36. Salih H. R., Starling G. C., Brandl S. Differentiation of promyelocytic leukemia: alterations in Fas (CD95/Apo-1) and Fas Ligand (CD178) expression, Br. J. Haematol., 2002, 117, 76-85.
37. Rezacova M., Vavrova J., Vokurkova D., Tichy A., Knizek J., Psutka J. The importance of abrogation of G2-phase arrest in combined effect of TRAIL and ionizing radiation, Acta Biochim. Pol., 2005, 52, 889-895.
38. Di Pietro R., Secchiero P., Rana R., Gibellini D., Visani G., Bermis K., et al. Ionizing radiation sensitizes erythroleucemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1, Blood, 2001, 97, 2596-2603.
39. Jonsson Z. O., Hubschner U. Proliferating cell nuclear antigen: more than a clamp for DNA polymerase, Bioassays, 1997, 19, 967-975.
40. Prosperi E. Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control, Progr. Cell Cycle Res., 1997, 3, 193-210.
41. Grzanka A., Skok Z., Janiak A., Grzanka D. The expression of proliferating cell nuclear antigen (PCNA) in leukemia cell lines HL-60 and K-562 at the light and electron microscope level, Neoplasma, 2000, 47, 288-293.
42. Sendler A., Kaffenberg W., Nuyken I., van Beuningen D. Proliferating kinetics and PCNA expression of HL-60 cells following ionizing irradiation and granulocytic differentiation, Cell Prolif., 1993, 6, 531-543.
43. Kobayashi M., Okamoto K., Namikawa T., Okabayashi T., Araki K. The changes of proliferating cell nuclear antigen and apoptosis of the MM46 mammary cancer cells of the mouse after single high-dose irradiation, Med. Mol. Morphol., 2005, 38, 181-188.
44. Yang E., Korsmeyer S. J. Molecular thanatopsis: A discourse on the BCL2 family and cell death, Blood, 1996, 88, 386-401.
45. Kroemer G. The proto-oncogene bcl-2 and its role in regulating apoptotic cell death, Nat. Med., 1997, 3, 617-620.
46. Maung Z. T., MacLean F. R., Reid M. M., Pearson A. D. J, Proctor S. J., Hamilton P. J., et al. The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia, Br. J. Haematol., 1994, 88, 105-109.
47. Campos L., Rouault J.-P., Sabido O., Oriol P., Roubi N., Vasselon C., et al. High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response in chemotherapy, Blood, 1993, 81, 3091-3096.
48. Andreef M., Jiang S., Zhang X., Konopleva M., Estrov Z., Snell V. E., et al. Expression of Bcl-2- related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid, Leukemia, 1999, 13, 1881-1892.
49. Kumakura S., Ishikura H., Tsumura H., Nakashima A., Stato Y., Kobyashi S. Cell-cycle-independent down-regulation of BCL-2 protein expression in differentiating HL-60 cells, Leuk. Lymphoma, 2000, 36, 375-382.
50. Ahmed N., Laverick L., Sammons J., Baumforth K. R., Hassan H. T. Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bcl-2 in human myeloid leukaemia CD34 positive cells, Leuk. Res., 1999, 8, 741-749.
51. Kariya S., Ogawa Y., Yoshida S., Yabuki M., Imajo Y., Utsumi K. X-irradiation enhances the expression of Bcl-2 in HL-60 cells: the resulting effects on apoptosis and radiosensitivity, Int. J. Mol. Med., 1999, 3, 145-152.
52. Bradbury D. A., Zhu Y. M., Russe N. H. Bcl-2 expression in acute myeloblastic leukaemia: relationship with autonomous growth and CD34 antigen expression, Leuk. Lymphoma, 1997, 24, 221-228.
53. Pelengaris S., Khan M., Evan G. I. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression, Cell, 2002, 109, 321-334.
54. Henriksson M., Luscher B. Proteins of the Myc network: essential regulators of cell growth and differentiation, Adv. Cancer Res., 1996, 68, 109-182.
55. Kumakura S., Ishikura H., Tsumura H., Iwata H., Endo J., Kobyashi S. c-Myc and Bcl-2 protein expression during the induction of apoptosis and differentiation in TNF alpha-treated HL-60 cells, Leuk. Lymphoma, 1996, 23, 383-394.
56. Dimberg A., Bahram F., Karlberg I., Larsson L.-G., Nilsson K., Oberg F. Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional upregulation of p27 Kip1, Blood, 2007, 99, 2199-2206.
57. MacLean K. H., Keller U. B., Rodriquez-Galindo C., Nilsson J. A., Cleveland J. L. c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL, Mol. Cell Biol., 2003, 23, 7256-7270.
58. Enomoto A., Suzuki N., Kang Y., Hirano K., Matsumoto Y., Zhu J., et al. Decreased c-Myc expression and its involvement in X-ray-induced apoptotic cell death of human T-cell leukaemia cell line MOLT-4, Int. J. Radiat. Biol., 2003, 79, 589-600.
59. Uckun F. M., Tuel-Ahlgren L., Song C. W., Waddick K., Myers D. E., Kirihara T, et al. Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death, Proc. Natl. Acad. Sci. USA, 1992, 89, 9005-9009.
60. Treigyte G., Navakauskiene R., Kulyte A., Gineitis A., Magnusson K.-E. Tyrosine phosphorylation of cytoplasmic proteins in proliferating, differentiating, apoptotic HL-60 cells and blood neutrophils, Cell. Mol. Life Sci., 2000, 57, 1997-2008.
61. Navakauskiene R., Treigyte G., Gineitis A., Magnusson K.-E. Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatement, Proteomics, 2004, 4, 1029-1041.
62. Komada F., Nishikawa M., Uemura Y., Morita K., Hidaka H. Expression of three major protein kinase C isozymes in various types of human leukemic cells, Cancer Res., 1991, 51, 4271-4278.
63. Savickiene J., Gineitis A., Shanbhag V. P., Stigbrand T. Protein kinase inhibitors exert stage specific and inducer dependent effects on HL-60 cell differentiation, Anticancer Res., 1995, 15, 687-962.
64. Ruvolo P. P., Deng X., Carr B. K., May S. A functional role for mitochondrial protein kinase Cα in Bcl2 phosphorylation and suppression of apoptosis, J. Biol. Chem., 1998, 273, 25436-25442.
65. Wang H. G., Rapp U. R., Reed J. C. Bcl-2 targets the protein kinase Raf-1 to mitochondria, Cell, 1996, 87, 629-638.
66. Gamard C. J., Blode G. C., Hannun Y. A., Obeid L. M. Specific role for protein kinase Cβ in cell differentiation, Cell Growth Differ., 1994, 5, 405-409.
67. Tonetti D., Henning-Chubb C., Yamanishi D., Huberman E. Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells, J. Biol. Chem., 1994, 269, 23230-23235.
68. Laouar A., Glesne D., Huberman E. Involvement of protein kinase C-β and ceramide in tumor necrosis factor-α-induced but not Fas-induced apoptosis of human myeloid leukemia cells, J. Biol. Chem., 1999, 274, 23526-23534.