Ex vivo fucosylation to improve the engraftment capability and therapeutic potential of human cord blood stem cells

Drug Discovery Today

Volumn 15, Issue 17-18, 2010, Pages 698-699

  Taupin, Philippe ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL HOMING; CORD BLOOD STEM CELL TRANSPLANTATION; EDITORIAL; ENGRAFTMENT; FANCONI ANEMIA; FUCOSYLATION; HUMAN; UMBILICAL CORD BLOOD;

CORD BLOOD STEM CELL TRANSPLANTATION; FUCOSE; HEMATOPOIETIC STEM CELLS; HUMANS;

EID: 77955784323     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2010.05.006     Document Type: Editorial

References (17)

1. Thomas E.D. History, current results, and research in marrow transplantation. Perspect. Biol. Med. 1995, 38:230-237.
2. Wang J.C., et al. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay. Blood 1997, 89:3919-3924.
3. Broxmeyer H.E., et al. Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:4109-4113.
4. Kurtzberg J., et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N. Engl. J. Med. 1996, 335:157-166.
5. Gluckman E., et al. Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilicalcord blood from an HLA-identical sibling. N. Engl. J. Med. 1989, 321:1174-1178.
6. Ballen K. Challenges in umbilical cord blood stem cell banking for stem cell reviews and reports. Stem Cell Rev. 2010, 6:8-14.
7. Barker J.N., et al. Umbilical cord blood transplantation: current practice and future innovations. Crit. Rev. Oncol. Hematol. 2003, 48:35-43.
8. Kelly S.S., et al. Overcoming the barriers to umbilical cord blood transplantation. Cytotherapy 2010, 12:121-130.
9. McNiece I.K., et al. Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential. Exp. Hematol. 2002, 30:612-616.
10. Long G.D., et al. Unrelated umbilical cord blood transplantation in adult patients. Biol. Blood Marrow Transplant. 2003, 9:772-780.
11. Lapidot T., et al. How do stem cells find their way home?. Blood 2005, 106:1901-1910.
12. Katayama Y., et al. PSGL-1 participates in Eselectin-mediated progenitor homing to bone marrow: evidence for cooperation between Eselectin ligands and 4 integrin. Blood 2003, 102:2060-2067.
13. Hidalgo A., et al. Functional selectin ligands mediating human CD34+ cell interactions with bone marrow endothelium are enhanced postnatally. J. Clin. Invest. 2002, 110:559-569.
14. McEver R.P. Selectins: lectins that initiate cell adhesion under flow. Curr. Opin. Cell. Biol. 2002, 14:581-586.
15. Fuhlbrigge R.C., et al. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 1997, 389:978-981.
16. Wagers A.J., et al. Interleukin 12 and interleukin 4 control cell adhesion to endothelial selectins through opposite effects on 1,3-fucosyltransferase VII gene expression. J. Exp. Med. 1998, 188:2225-2231.
17. Xia L., et al. Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. Blood 2004, 104:3091-3096.