The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice

Hearing Research

Volumn 268, Issue 1-2, 2010, Pages 46-59

  Tan, Justin ^a,b   Clarke, Maria ^b   Barrett, G ^b   Millard, R ^b  

^a BIONIC EAR INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN RECEPTOR P75;

ACOUSTIC NERVE FIBER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD SHIFT; CELL PROTECTION; CELL SURVIVAL; COCHLEA INJURY; CONTROLLED STUDY; CORTI ORGAN; HISTOPATHOLOGY; MOUSE; MOUSE MUTANT; NERVE CELL DEGENERATION; NEUROPROTECTION; NOISE INJURY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHWANN CELL; WILD TYPE;

ACOUSTIC STIMULATION; ANIMALS; AUDITORY THRESHOLD; CELL DEATH; COCHLEA; COCHLEAR NERVE; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENOTYPE; HEARING LOSS, NOISE-INDUCED; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NOISE; PHENOTYPE; RECEPTORS, NERVE GROWTH FACTOR; SCHWANN CELLS; SPECIES SPECIFICITY; TIME FACTORS; UP-REGULATION;

EID: 77955773055     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2010.04.013     Document Type: Article

References (42)

1. Ahituv N., Avraham K.B. Mouse models for human deafness: current tools for new fashions. Trends in Molecular Medicine 2002, 8:447-451.
2. Beattie M.S., Harrington A.W., Lee R., Kim J.Y., Boyce S.L., Longo F.M., Bresnahan J.C., Hempstead B.L., Yoon S.O. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 2002, 36:375-386.
3. Bibel M., Hoppe E., Barde Y.A. Biochemical and functional interactions between the neurotrophin receptors trk and p75(NTR). EMBO Journal 1999, 18:616-622.
4. Brors D., Hansen S., Mlynski R., Volkenstein S., Aletsee C., Sendtner M., Ryan A.F., Dazert S. Spiral ganglion outgrowth and hearing development in p75(NTR)-deficient mice. Audiology and Neuro-otology 2008, 13:388-395.
5. Chu G.K.T., Yu W., Fehlings M.G. The p75 neurotrophin receptor is essential for neuronal cell survival and improvement of functional recovery after spinal cord injury. Neuroscience 2007, 148:668-682.
6. Davis R.R., Newlander J.K., Ling X.B., Cortopassi G.A., Krieg E.F., Erway L.C. Genetic basis for susceptibility to noise-induced hearing loss in mice. Hearing Research 2001, 155:82-90.
7. Dechant G., Barde Y.A. The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nature Neuroscience 2002, 5:1131-1136.
8. Dodson H.C. Loss and survival of spiral ganglion neurons in the guinea pig after intracochlear perfusion with aminoglycosides. Journal of Neurocytology 1997, 26:541-556.
9. Epa W.R., Markovska K., Barrett G.L. The p75 neurotrophin receptor enhances TrkA signalling by binding to Shc and augmenting its phosphorylation. Journal of Neurochemistry 2004, 89:344-353.
10. Ernfors P., Vandewater T., Loring J., Jaenisch R. Complementary roles of Bdnf and Nt-3 in vestibular and auditory development. Neuron 1995, 14:1153-1164.
11. Esposito D., Patel P., Stephens R.M., Perez P., Chao M.V., Kaplan D.R., Hempstead B.L. The cytoplasmic and transmembrane domains of the p75 and Trk a receptors regulate high affinity binding to nerve growth factor. Journal of Biological Chemistry 2001, 276:32687-32695.
12. Fritzsch B., Farinas I., Reichardt L.F. Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in region-specific fashion. Journal of Neuroscience 1997, 17:6213-6225.
13. Fritzsch B., Barbacid M., Silos-Santiago I. The combined effects of trkB and trkC mutations on the innervation of the inner ear. International Journal of Developmental Neuroscience 1998, 16:493-505.
14. Gestwa G., Wiechers B., Zimmermann U., Praetorius M., Rohbock K., Kopschall I., Zenner H.P., Knipper M. Differential expression of trkB.T1 and trkB.T2, truncated trkC, and p75(NGFR) in the cochlea prior to hearing function. Journal of Comparative Neurology 1999, 414:33-49.
15. Gillespie L.N., Clark G.M., Bartlett P.F., Marzella P.L. BDNF-induced survival of auditory neurons in vivo: cessation of treatment leads to accelerated loss of survival effects. Journal of Neuroscience Research 2003, 71:785-790.
16. Hamanoue M., Middleton G., Wyatt S., Jaffray E., Hay R.T., Davies A.M. p75-mediated NF-kappa B activation enhances the survival response of developing sensory neurons to nerve growth factor. Molecular and Cellular Neuroscience 1999, 14:28-40.
17. Harrington A.W., Leiner B., Blechschmitt C., Arevalo J.C., Lee R., Morl L., Meyer M., Hempstead B.L., Yoon S.O., Giehl K.M. Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:6226-6230.
18. Hempstead B.L. The many faces of p75(NTR). Current Opinion in Neurobiology 2002, 12:260-267.
19. Holme R.H., Steel K.P. Progressive hearing loss and increased susceptibility to noise-induced hearing loss in mice carrying a Cdh23 but not a Myo7a mutation. JARO-Journal of the Association for Research in Otolaryngology 2004, 5:66-79.
20. Huang E.J., Reichardt L.F. Trk receptors: roles in neuronal signal transduction. Annual Review of Biochemistry 2003, 72:609-642.
21. Johnson K.R., Zheng Q.Y., Noben-Trauth K. Strain background effects and genetic modifiers of hearing in mice. Brain Research 2006, 1091:79-88.
22. Keithley E.M., Canto C., Zheng Q.Y., Fischel-Ghodsian N., Johnson K.R. Age-related hearing loss and the ahl locus in mice. Hearing Research 2004, 188:21-28.
23. Lang H.N., Schulte B.A., Zhou D.H., Smythe N., Spicer S.S., Schmiedt R.A. Nuclear factor kappa B deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. Journal of Neuroscience 2006, 26:3541-3550.
24. Lee K.F., Li E., Huber L.J., Landis S.C., Sharpe A.H., Chao M.V., Jaenisch R. Targeted mutation of the gene encoding the low affinity Ngf receptor P75 leads to deficits in the peripheral sensory nervous system. Cell 1992, 69:737-749.
25. Lee R., Kermani P., Teng K.K., Hempstead B.L. Regulation of cell survival by secreted proneurotrophins. Science 2001, 294:1945-1948.
26. Mowla S.J., Farhadi H.F., Pareek S., Atwal J.K., Morris S.J., Seidah N.G., Murphy R.A. Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor. Journal of Biological Chemistry 2001, 276:12660-12666.
27. Mufson E.J., Kordower J.H. Cortical-neurons express nerve growth-factor receptors in advanced age and Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America 1992, 89:569-573.
28. Murray S.S., Bartlett P.F., Lopes E.C., Coulson E.J., Greferath U., Cheema S.S. Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons. Clinical and Experimental Pharmacology and Physiology 2003, 30:217-222.
29. Naumann T., Casademunt E., Hollerbach E., Hofmann J., Dechant G., Frotscher M., Barde Y.A. Complete deletion of the neurotrophin receptor p75(NTR) leads to long-lasting increases in the number of basal forebrain cholinergic neurons. Journal of Neuroscience 2002, 22:2409-2418.
30. Noben-Trauth K., Zheng Q.Y., Johnson K.R. Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nature Genetics 2003, 35:21-23.
31. NobenTrauth K., Zheng Q.Y., Johnson K.R., Nishina P.M. mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw). Genomics 1997, 44:266-272.
32. Oestreicher E., Knipper M., Arnold A., Zenner H.P., Felix D. Neurotrophin 3 potentiates glutamatergic responses of IHC afferents in the cochlea in vivo. European Journal of Neuroscience 2000, 12:1584-1590.
33. Sato T., Doi K., Taniguchi M., Yamashita T., Kubo T., Tohyama M. Progressive hearing loss in mice carrying a mutation in the p75 gene. Brain Research 2006, 1091:224-234.
34. Schimmang T., Minichiello L., Vazquez E., Jose I.S., Giraldez F., Klein R., Represa J. Developing inner-ear sensory neurons Require Trkb and Trkc receptors for innervation of their peripheral targets. Development 1995, 121:3381-3391.
35. Schimmang T., Tan J., Muller M., Zimmermann U., Rohbock K., Kopschall I., Limberger A., Minichiello L., Knipper M. Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss. Development 2003, 130:4741-4750.
36. Segal R.A. Selectivity inneurotrophin signaling: theme and variations. Annual Review of Neuroscience 2003, 26:299-330.
37. Spongr V.P., Flood D.G., Frisina R.D., Salvi R.J. Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans. Journal of the Acoustical Society of America 1997, 101:3546-3553.
38. Stankovic K., Rio C., Xia A.P., Sugawara M., Adams J.C., Liberman M.C., Corfas G. Survival of adult spiral ganglion neurons requires erbB receptor signaling in the inner ear. Journal of Neuroscience 2004, 24:8651-8661.
39. Tan J., Shepherd R.K. Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling. American Journal of Pathology 2006, 169:528-543.
40. Teng H.K., Teng K.K., Lee R., Wright S., Tevar S., Almeida R.D., Kermani P., Torkin R., Chen Z.Y., Lee F.S., Kraemer R.T., Nykjaer A., Hempstead B.L. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75(NTR) and sortilin. Journal of Neuroscience 2005, 25:5455-5463.
41. Wiechers B., Gestwa G., Mack A., Carroll P., Zenner H.P., Knipper M. A changing pattern of brain-derived neurotrophic factor expression correlates with the rearrangement of fibers during cochlear development of rats and mice. Journal of Neuroscience 1999, 19:3033-3042.
42. Ylikoski J., Pirvola U., Moshnyakov M., Palgi J., Arumae U., Saarma M. Expression patterns of neurotrophin and their receptor messenger-RNAs in the rat inner-ear. Hearing Research 1993, 65:69-78.