Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons

Clinical and Experimental Pharmacology and Physiology

Volumn 30, Issue 4, 2003, Pages 217-222

  Murray, Simon S ^a   Bartlett, Perry F ^b   Lopes, Elizabeth C ^a   Coulson, Elizabeth J ^b   Greferath, Una ^b   Cheema, Surindar S ^a  

^a MONASH UNIVERSITY   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Antisense treatment; Axotomy; Death signalling; Neuronal cell death; Neurotrophin receptor; P75NTR knockout mouse

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LIGAND; NEUROTROPHIN RECEPTOR; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; EXON; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MOUSE; MUTATION; NERVE CELL; NERVE FIBER TRANSECTION; NEWBORN; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AXOTOMY; BINDING SITES; EXONS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MOTOR NEURONS; MUTATION; NEURONS, AFFERENT; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; SCIATIC NERVE; SPINE;

EID: 0037394793     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2003.03827.x     Document Type: Article

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