Tamoxifen dose response and conditional cell marking: Is there control?

Molecular and Cellular Neuroscience

Volumn 45, Issue 2, 2010, Pages 132-138

  Ellisor, Debra ^a   Zervas, Mark ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Cell lineage; Conditional phenotyping alleles; Genetic Inducible Fate Mapping; Tamoxifen; Trigeminal ganglia; Wnt1 CreERT

Indexed keywords

CRE RECOMBINASE; CRE RECOMBINASE ESTROGEN RECEPTOR LIGAND BINDING DOMAIN PROTEIN; HYBRID PROTEIN; TAMOXIFEN; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; GENE INACTIVATION; GENETIC INDUCIBLE FATE MAPPING; GENETIC PROCEDURES; GENETIC RECOMBINATION; GENOTYPE; MALE; MOUSE; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; TRIGEMINUS GANGLION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, TRANSGENIC; NEURAL STEM CELLS; RECOMBINATION, GENETIC; TAMOXIFEN; TRIGEMINAL GANGLION; WNT1 PROTEIN;

EID: 77955771678     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2010.06.004     Document Type: Article

References (25)

1. Ahn S., Joyner A.L. Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 2004, 118:505-516.
2. Beck S.L. Effects of position in the uterus on fetal mortality and on response to trypan blue. J. Embryol. Exp. Morphol. 1967, 17:617-624.
3. Branda C.S., Dymecki S.M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 2004, 6:7-28.
4. Brown A., Brown S., Ellisor D., Hagan N., Normand E., Zervas M. A practical approach to genetic inducible fate mapping: a visual guide to mark and track cells in vivo. J. Vis. Exp. 2009.
5. Chen L., Guo Q., Li J.Y. Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus. Development 2009, 136:1317-1326.
6. Danielian P.S., Muccino D., Rowitch D.H., Michael S.K., McMahon A.P. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr. Biol. 1998, 8:1323-136.
7. Dymecki S.M., Kim J.C. Molecular neuroanatomy's "Three Gs": a primer. Neuron 2007, 54:17-34.
8. Ellisor D., Koveal D., Hagan N., Brown A., Zervas M. Comparative analysis of conditional reporter alleles in the developing embryo and embryonic nervous system. Gene Expr. Patterns 2009, 9:475-489.
9. Erzurumlu R.S., Murakami Y., Rijli F.M. Mapping the face in the somatosensory brainstem. Nat. Rev. Neurosci. 2010, 11:252-263.
10. Feil R., Brocard J., Mascrez B., LeMeur M., Metzger D., Chambon P. Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:10887-11090.
11. Feil R., Wagner J., Metzger D., Chambon P. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun. 1997, 237:752-757.
12. Graff-Radford S.B. Facial pain. Neurologist 2009, 15:171-177.
13. Guo C., Yang W., Lobe C.G. A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action. Genesis 2002, 32:8-18.
14. Hayashi S., McMahon A.P. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev. Biol. 2002, 244:305-318.
15. Hippenmeyer S., Vrieseling E., Sigrist M., Portmann T., Laengle C., Ladle D.R., Arber S. A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005, 3:e159.
16. Indra A.K., Warot X., Brocard J., Bornert J.M., Xiao J.H., Chambon P., Metzger D. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 1999, 27:4324-4327.
17. Joyner A.L., Zervas M. Genetic inducible fate mapping in mouse: establishing genetic lineages and defining genetic neuroanatomy in the nervous system. Dev. Dyn. 2006, 235:2376-2385.
18. Kimmel R.A., Turnbull D.H., Blanquet V., Wurst W., Loomis C.A., Joyner A.L. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 2000, 14:1377-1389.
19. Lazarov N.E. Neurobiology of orofacial proprioception. Brain Res. Rev. 2007, 56:362-383.
20. Lee L., Chu L.C., Sadowski P.D. Cre induces an asymmetric DNA bend in its target loxP site. J. Biol. Chem. 2003, 278:23118-23129.
21. Legué E., Nicolas J.F. Hair follicle renewal: organization of stem cells in the matrix and the role of stereotyped lineages and behaviors. Development 2005, 132:4143-4154.
22. Miner N.A., Koehler J., Greenaway L. Intraperitoneal injection of mice. Appl. Microbiol. 1969, 17:250-251.
23. Robinson S.P., Langan-Fahey S.M., Johnson D.A., Jordan V.C. Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient. Drug Metab. Dispos. 1991, 36-43.
24. Sgaier S.K., Millet S., Villanueva M.P., Berenshteyn F., Song C., Joyner A.L. Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping. Neuron 2005, 45:27-40.
25. Zervas M., Millet S., Ahn S., Joyner A.L. Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 2004, 43:345-357.