-
1
-
-
37248999372
-
Triple negative tumours: A critical review
-
Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathology 2008; 52:108-18.
-
(2008)
Histopathology
, vol.52
, pp. 108-118
-
-
Reis-Filho, J.S.1
Tutt, A.N.2
-
2
-
-
50849104285
-
Mechanisms of microRNA deregulation in human cancer
-
Deng S, Calin GA, Croce CM, Coukos G, Zhang L. Mechanisms of microRNA deregulation in human cancer. Cell Cycle 2008; 7:2643-6.
-
(2008)
Cell Cycle
, vol.7
, pp. 2643-2646
-
-
Deng, S.1
Calin, G.A.2
Croce, C.M.3
Coukos, G.4
Zhang, L.5
-
3
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006; 6:259-69.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
4
-
-
0033524475
-
Why is Hu where? Shuttling of early-response-gene messenger RNA subsets
-
Keene JD. Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. Proc Natl Acad Sci USA 1999; 96:5-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5-7
-
-
Keene, J.D.1
-
5
-
-
0035912793
-
Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome
-
Keene JD. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. Proc Natl Acad Sci USA 2001; 98:7018-24.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7018-7024
-
-
Keene, J.D.1
-
6
-
-
0348047595
-
Posttranscriptional generation of macromolecular complexes
-
Keene JD. Posttranscriptional generation of macromolecular complexes. Mol Cell 2003; 12:1347-9.
-
(2003)
Mol Cell
, vol.12
, pp. 1347-1349
-
-
Keene, J.D.1
-
7
-
-
0037315674
-
Organizing mRNA export
-
Keene JD. Organizing mRNA export. Nat Genet 2003; 33:111-2.
-
(2003)
Nat Genet
, vol.33
, pp. 111-112
-
-
Keene, J.D.1
-
8
-
-
0036289532
-
Eukaryotic mRNPs may represent posttranscriptional operons
-
Keene JD, Tenenbaum SA. Eukaryotic mRNPs may represent posttranscriptional operons. Mol Cell 2002; 9:1161-7.
-
(2002)
Mol Cell
, vol.9
, pp. 1161-1167
-
-
Keene, J.D.1
Tenenbaum, S.A.2
-
9
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
2342573011
-
HuR in the mammalian genotoxic response: Post-transcriptional multitasking
-
Gorospe M. HuR in the mammalian genotoxic response: post-transcriptional multitasking. Cell Cycle 2003; 2:412-4.
-
(2003)
Cell Cycle
, vol.2
, pp. 412-414
-
-
Gorospe, M.1
-
11
-
-
77953547289
-
miR-519 suppresses tumor growth by reducing HuR levels
-
Abdelmohsen K, Kim MM, Srikantan S, Mercken EM, Brennan SE, Wilson GM, et al. miR-519 suppresses tumor growth by reducing HuR levels. Cell Cycle 2010; 9.
-
(2010)
Cell Cycle
, vol.9
-
-
Abdelmohsen, K.1
Kim, M.M.2
Srikantan, S.3
Mercken, E.M.4
Brennan, S.E.5
Wilson, G.M.6
-
12
-
-
0031783046
-
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation
-
Atasoy U, Watson J, Patel D, Keene JD. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci 1998; 111:3145-56.
-
(1998)
J Cell Sci
, vol.111
, pp. 3145-3156
-
-
Atasoy, U.1
Watson, J.2
Patel, D.3
Keene, J.D.4
-
13
-
-
0025361155
-
Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer - A quantitative western blot analysis
-
Dalmau J, Furneaux HM, Gralla RJ, Kris MG, Posner JB. Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer - a quantitative western blot analysis. Ann Neurol 1990; 27:544-52.
-
(1990)
Ann Neurol
, vol.27
, pp. 544-552
-
-
Dalmau, J.1
Furneaux, H.M.2
Gralla, R.J.3
Kris, M.G.4
Posner, J.B.5
-
14
-
-
0025986452
-
Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy
-
Dalmau J, Furneaux HM, Rosenblum MK, Graus F, Posner JB. Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy. Neurology 1991; 41:1757-64.
-
(1991)
Neurology
, vol.41
, pp. 1757-1764
-
-
Dalmau, J.1
Furneaux, H.M.2
Rosenblum, M.K.3
Graus, F.4
Posner, J.B.5
-
15
-
-
0032526427
-
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
-
Fan XC, Steitz JA. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J 1998; 17:3448-60.
-
(1998)
EMBO J
, vol.17
, pp. 3448-3460
-
-
Fan, X.C.1
Steitz, J.A.2
-
16
-
-
0029873536
-
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
-
Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem 1996; 271:8144-51.
-
(1996)
J Biol Chem
, vol.271
, pp. 8144-8151
-
-
Ma, W.J.1
Cheng, S.2
Campbell, C.3
Wright, A.4
Furneaux, H.5
-
17
-
-
27744520451
-
HuR: Post-transcriptional paths to malignancy
-
Lopez de Silanes I, Lal A, Gorospe M. HuR: post-transcriptional paths to malignancy. RNA Biol 2005; 2:11-3.
-
(2005)
RNA Biol
, vol.2
, pp. 11-13
-
-
Lopez De Silanes, I.1
Lal, A.2
Gorospe, M.3
-
18
-
-
34547651351
-
Posttranscriptional orchestration of an anti-apoptotic program by HuR
-
Abdelmohsen K, Lal A, Kim HH, Gorospe M. Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle 2007; 6:1288-92.
-
(2007)
Cell Cycle
, vol.6
, pp. 1288-1292
-
-
Abdelmohsen, K.1
Lal, A.2
Kim, H.H.3
Gorospe, M.4
-
19
-
-
0037134484
-
A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR
-
Goldberg-Cohen I, Furneauxb H, Levy AP. A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR. J Biol Chem 2002; 277:13635-40.
-
(2002)
J Biol Chem
, vol.277
, pp. 13635-13640
-
-
Goldberg-Cohen, I.1
Furneauxb, H.2
Levy, A.P.3
-
20
-
-
0031685130
-
Hypoxic regulation of VEGF mRNA stability by RNA-binding proteins
-
Levy AP. Hypoxic regulation of VEGF mRNA stability by RNA-binding proteins. Trends Cardiovasc Med 1998; 8:246-50.
-
(1998)
Trends Cardiovasc Med
, vol.8
, pp. 246-250
-
-
Levy, A.P.1
-
21
-
-
0032513043
-
Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
-
Levy NS, Chung S, Furneaux H, Levy AP. Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J Biol Chem 1998; 273:6417-23.
-
(1998)
J Biol Chem
, vol.273
, pp. 6417-6423
-
-
Levy, N.S.1
Chung, S.2
Furneaux, H.3
Levy, A.P.4
-
22
-
-
37549037125
-
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha
-
Galban S, Kuwano Y, Pullmann R Jr, Martindale JL, Kim HH, Lal A, et al. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol 2008; 28:93-107.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 93-107
-
-
Galban, S.1
Kuwano, Y.2
Pullmann Jr., R.3
Martindale, J.L.4
Kim, H.H.5
Lal, A.6
-
23
-
-
20144389216
-
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma
-
Heinonen M, Bono P, Narko K, Chang SH, Lundin J, Joensuu H, et al. Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma. Cancer Res 2005; 65:2157-61.
-
(2005)
Cancer Res
, vol.65
, pp. 2157-2161
-
-
Heinonen, M.1
Bono, P.2
Narko, K.3
Chang, S.H.4
Lundin, J.5
Joensuu, H.6
-
24
-
-
37249017962
-
Prognostic role of HuR in hereditary breast cancer
-
Heinonen M, Fagerholm R, Aaltonen K, Kilpivaara O, Aittomaki K, Blomqvist C, et al. Prognostic role of HuR in hereditary breast cancer. Clin Cancer Res 2007; 13:6959-63.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6959-6963
-
-
Heinonen, M.1
Fagerholm, R.2
Aaltonen, K.3
Kilpivaara, O.4
Aittomaki, K.5
Blomqvist, C.6
-
25
-
-
16744361844
-
Role of the RNA-binding protein HuR in colon carcinogenesis
-
Lopez de Silanes I, Fan J, Yang X, Zonderman AB, Potapova O, Pizer ES, et al. Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene 2003; 22:7146-54.
-
(2003)
Oncogene
, vol.22
, pp. 7146-7154
-
-
Lopez De Silanes, I.1
Fan, J.2
Yang, X.3
Zonderman, A.B.4
Potapova, O.5
Pizer, E.S.6
-
26
-
-
58149172080
-
Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells
-
Hostetter C, Licata LA, Witkiewicz A, Costantino CL, Yeo CJ, Brody JR, et al. Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells. Cancer Biol Ther 2008; 7.
-
(2008)
Cancer Biol Ther
, vol.7
-
-
Hostetter, C.1
Licata, L.A.2
Witkiewicz, A.3
Costantino, C.L.4
Yeo, C.J.5
Brody, J.R.6
-
27
-
-
54049135560
-
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
-
Mazan-Mamczarz K, Hagner PR, Corl S, Srikantan S, Wood WH, Becker KG, et al. Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype. Oncogene 2008; 27:6151-63.
-
(2008)
Oncogene
, vol.27
, pp. 6151-6163
-
-
Mazan-Mamczarz, K.1
Hagner, P.R.2
Corl, S.3
Srikantan, S.4
Wood, W.H.5
Becker, K.G.6
-
28
-
-
0034657686
-
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
-
Wang W, Caldwell MC, Lin S, Furneaux H, Gorospe M. HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J 2000; 19:2340-50.
-
(2000)
EMBO J
, vol.19
, pp. 2340-2350
-
-
Wang, W.1
Caldwell, M.C.2
Lin, S.3
Furneaux, H.4
Gorospe, M.5
-
29
-
-
55549120187
-
siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo
-
Raskopf E, Vogt A, Sauerbruch T, Schmitz V. siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo. J Hepatol 2008; 49:977-84.
-
(2008)
J Hepatol
, vol.49
, pp. 977-984
-
-
Raskopf, E.1
Vogt, A.2
Sauerbruch, T.3
Schmitz, V.4
-
30
-
-
35348817465
-
Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model
-
Whitehurst B, Flister MJ, Bagaitkar J, Volk L, Bivens CM, Pickett B, et al. Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model. Int J Cancer 2007; 121:2181-91.
-
(2007)
Int J Cancer
, vol.121
, pp. 2181-2191
-
-
Whitehurst, B.1
Flister, M.J.2
Bagaitkar, J.3
Volk, L.4
Bivens, C.M.5
Pickett, B.6
-
31
-
-
77949407821
-
A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models
-
Yu Y, Lee P, Ke Y, Zhang Y, Yu Q, Lee J, et al. A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models. PLoS One 2010; 5:9072.
-
(2010)
PLoS One
, vol.5
, pp. 9072
-
-
Yu, Y.1
Lee, P.2
Ke, Y.3
Zhang, Y.4
Yu, Q.5
Lee, J.6
-
32
-
-
54249135733
-
Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis
-
Zhang J, Lu A, Beech D, Jiang B, Lu Y. Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis. Cancer Ther 2007; 5:273-86.
-
(2007)
Cancer Ther
, vol.5
, pp. 273-286
-
-
Zhang, J.1
Lu, A.2
Beech, D.3
Jiang, B.4
Lu, Y.5
-
34
-
-
0032770860
-
Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas
-
Streit M, Velasco P, Brown LF, Skobe M, Richard L, Riccardi L, et al. Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. Am J Pathol 1999; 155:441-52.
-
(1999)
Am J Pathol
, vol.155
, pp. 441-452
-
-
Streit, M.1
Velasco, P.2
Brown, L.F.3
Skobe, M.4
Richard, L.5
Riccardi, L.6
-
35
-
-
68149165414
-
HuR recruits let-7/RISC to repress c-Myc expression
-
Kim HH, Kuwano Y, Srikantan S, Lee EK, Martindale JL, Gorospe M. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 2009; 23:1743-8.
-
(2009)
Genes Dev
, vol.23
, pp. 1743-1748
-
-
Kim, H.H.1
Kuwano, Y.2
Srikantan, S.3
Lee, E.K.4
Martindale, J.L.5
Gorospe, M.6
-
36
-
-
24944468765
-
HuR as a negative post-transcriptional modulator in inflammation
-
Katsanou V, Papadaki O, Milatos S, Blackshear PJ, Anderson P, Kollias G, et al. HuR as a negative post-transcriptional modulator in inflammation. Mol Cell 2005; 19:777-89.
-
(2005)
Mol Cell
, vol.19
, pp. 777-789
-
-
Katsanou, V.1
Papadaki, O.2
Milatos, S.3
Blackshear, P.J.4
Anderson, P.5
Kollias, G.6
-
37
-
-
12144251356
-
The AU-rich transcriptome: More than interferons and cytokines and its role in disease
-
Khabar KS. The AU-rich transcriptome: more than interferons and cytokines and its role in disease. J Interferon Cytokine Res 2005; 25:1-10.
-
(2005)
J Interferon Cytokine Res
, vol.25
, pp. 1-10
-
-
Khabar, K.S.1
-
38
-
-
12844271570
-
AU-rich transient response transcripts in the human genome: Expressed sequence tag clustering and gene discovery approach
-
Khabar KS, Bakheet T, Williams BR. AU-rich transient response transcripts in the human genome: expressed sequence tag clustering and gene discovery approach. Genomics 2005; 85:165-75.
-
(2005)
Genomics
, vol.85
, pp. 165-175
-
-
Khabar, K.S.1
Bakheet, T.2
Williams, B.R.3
-
39
-
-
5644245066
-
mRNA openers and closers: Modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure
-
Meisner NC, Hackermuller J, Uhl V, Aszodi A, Jaritz M, Auer M. mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure. Chembiochem 2004; 5:1432-47.
-
(2004)
Chembiochem
, vol.5
, pp. 1432-1447
-
-
Meisner, N.C.1
Hackermuller, J.2
Uhl, V.3
Aszodi, A.4
Jaritz, M.5
Auer, M.6
-
40
-
-
0038450334
-
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes
-
Figueroa A, Cuadrado A, Fan J, Atasoy U, Muscat GE, Munoz-Canoves P, et al. Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol 2003; 23:4991-5004.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4991-5004
-
-
Figueroa, A.1
Cuadrado, A.2
Fan, J.3
Atasoy, U.4
Muscat, G.E.5
Munoz-Canoves, P.6
-
41
-
-
0344875497
-
RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation
-
van der Giessen K, Di-Marco S, Clair E, Gallouzi IE. RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation. J Biol Chem 2003; 278:47119-28.
-
(2003)
J Biol Chem
, vol.278
, pp. 47119-47128
-
-
Van Der Giessen, K.1
Di-Marco, S.2
Clair, E.3
Gallouzi, I.E.4
-
42
-
-
77950527724
-
The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer
-
Calaluce R, Gubin MM, Davis JW, Magee JD, Chen J, Kuwano Y, et al. The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer. BMC Cancer 2010; 10:126.
-
(2010)
BMC Cancer
, vol.10
, pp. 126
-
-
Calaluce, R.1
Gubin, M.M.2
Davis, J.W.3
Magee, J.D.4
Chen, J.5
Kuwano, Y.6
-
43
-
-
56049123873
-
HuR and the bioenergetic signature of breast cancer: A low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence
-
Ortega AD, Sala S, Espinosa E, Gonzalez-Baron M, Cuezva JM. HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence. Carcinogenesis 2008; 29:2053-61.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2053-2061
-
-
Ortega, A.D.1
Sala, S.2
Espinosa, E.3
Gonzalez-Baron, M.4
Cuezva, J.M.5
-
44
-
-
70349578806
-
Tamoxifen induces regression of estradiol-induced mammary cancer in the ACI. COP-Ept2 rat model
-
Ruhlen RL, Willbrand DM, Besch-Williford CL, Ma L, Shull JD, Sauter ER. Tamoxifen induces regression of estradiol-induced mammary cancer in the ACI. COP-Ept2 rat model. Breast Cancer Res Treat 2009; 117:517-24.
-
(2009)
Breast Cancer Res Treat
, vol.117
, pp. 517-524
-
-
Ruhlen, R.L.1
Willbrand, D.M.2
Besch-Williford, C.L.3
Ma, L.4
Shull, J.D.5
Sauter, E.R.6
-
45
-
-
33644872577
-
Limma: Linear models for microarray data
-
Gentleman RCV, Dudoit S, Irizarry R, Huber W, Ed. New York: Springer
-
Smyth G. Limma: linear models for microarray data in: Bioinformatics and computational Biology Solutions. In: Gentleman RCV, Dudoit S, Irizarry R, Huber W, Ed. New York: Springer 2005.
-
(2005)
Bioinformatics and Computational Biology Solutions
-
-
Smyth, G.1
-
46
-
-
46249088370
-
lumi: A pipeline for processing Illumina microarray
-
Du P, Kibbe WA, Lin SM. lumi: a pipeline for processing Illumina microarray. Bioinformatics 2008; 24:1547-8.
-
(2008)
Bioinformatics
, vol.24
, pp. 1547-1548
-
-
Du, P.1
Kibbe, W.A.2
Lin, S.M.3
-
47
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5:80.
-
(2004)
Genome Biol
, vol.5
, pp. 80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
-
48
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society 1995; 57:289-300.
-
(1995)
Journal of the Royal Statistical Society
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
52
-
-
33846689706
-
Using GOstats to test gene lists for GO term association
-
Falcon S, Gentleman R. Using GOstats to test gene lists for GO term association. Bioinformatics 2007; 23:257-8.
-
(2007)
Bioinformatics
, vol.23
, pp. 257-258
-
-
Falcon, S.1
Gentleman, R.2
-
53
-
-
33745626459
-
Improved scoring of functional groups from gene expression data by decorrelationg GO graph structure
-
Alexa A, Rahnenfuhrer J, Lengauer T. Improved scoring of functional groups from gene expression data by decorrelationg GO graph structure. Bioinformatics 2006; 22:1600-7.
-
(2006)
Bioinformatics
, vol.22
, pp. 1600-1607
-
-
Alexa, A.1
Rahnenfuhrer, J.2
Lengauer, T.3
|