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Volumn 70, Issue 16, 2010, Pages 6587-6597

Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE 9; N [5 (5 TERT BUTYL 2 OXAZOLYLMETHYLTHIO) 2 THIAZOLYL]ISONIPECOTAMIDE; ONCOPROTEIN; PROTEIN MCL 1; SMALL INTERFERING RNA; CCND1 PROTEIN, HUMAN; MYELOID LEUKEMIA FACTOR 1; N-(5-(((5-(1,1-DIMETHYLETHYL)-2-OXAZOLYL)METHYL)THIO)-2-THIAZOLYL)-4-PIPERIDINECARBOXAMIDE; OXAZOLE DERIVATIVE; PROTEIN BCL 2; RNA; SMALL NUCLEAR RNA; THIAZOLE DERIVATIVE;

EID: 77955720554     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3578     Document Type: Article
Times cited : (27)

References (40)
  • 1
    • 34648824397 scopus 로고    scopus 로고
    • Genetic and molecular pathogenesis of mantle cell lymphoma: Perspectives for new targeted therapeutics
    • DOI 10.1038/nrc2230, PII NRC2230
    • Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 2007;7:750-62. (Pubitemid 47463673)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.10 , pp. 750-762
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 2
    • 47149105457 scopus 로고    scopus 로고
    • Mantle cell lymphoma: Advances in biology and therapy
    • Smith MR. Mantle cell lymphoma: advances in biology and therapy. Curr Opin Hematol 2008;15:415-21.
    • (2008) Curr Opin Hematol , vol.15 , pp. 415-421
    • Smith, M.R.1
  • 3
    • 24144472585 scopus 로고    scopus 로고
    • Biology and therapy of mantle cell lymphoma
    • Williams ME, Densmore JJ. Biology and therapy of mantle cell lymphoma. Curr Opin Oncol 2005;17:425-31.
    • (2005) Curr Opin Oncol , vol.17 , pp. 425-431
    • Williams, M.E.1    Densmore, J.J.2
  • 4
    • 68149162135 scopus 로고    scopus 로고
    • SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples
    • Conroy A, Stockett DE, Walker D, et al. SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples. Cancer Chemother Pharmacol 2009;64:723-32.
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 723-732
    • Conroy, A.1    Stockett, D.E.2    Walker, D.3
  • 5
    • 66549124708 scopus 로고    scopus 로고
    • Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia
    • Chen R, Wierda WG, Chubb S, et al. Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia. Blood 2009;113:4637-45.
    • (2009) Blood , vol.113 , pp. 4637-4645
    • Chen, R.1    Wierda, W.G.2    Chubb, S.3
  • 6
    • 77954611291 scopus 로고    scopus 로고
    • Phase I study of SNS-032, a potent and specific Cdk2, 7 and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia (CLL) and multiple myeloma (MM)
    • Tong WG, Chen R, Plunkett W, et al. Phase I study of SNS-032, a potent and specific Cdk2, 7 and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). J Clin Oncol 2010;28:3015-22.
    • (2010) J Clin Oncol , vol.28 , pp. 3015-3022
    • Tong, W.G.1    Chen, R.2    Plunkett, W.3
  • 7
    • 38149008164 scopus 로고    scopus 로고
    • A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors
    • Heath EI, Bible K, Martell RE, Adelman DC, Lorusso PM. A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors. Invest New Drugs 2008;26:59-65.
    • (2008) Invest New Drugs , vol.26 , pp. 59-65
    • Heath, E.I.1    Bible, K.2    Martell, R.E.3    Adelman, D.C.4    Lorusso, P.M.5
  • 9
  • 10
    • 70349925289 scopus 로고    scopus 로고
    • Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: Roles of energy depletion and inhibition of DNA and RNA synthesis
    • Dennison JB, Balakrishnan K, Gandhi V. Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis. Br J Haematol 2009;147:297-307.
    • (2009) Br J Haematol , vol.147 , pp. 297-307
    • Dennison, J.B.1    Balakrishnan, K.2    Gandhi, V.3
  • 11
    • 58149181363 scopus 로고    scopus 로고
    • Cell Line Data Base: Structure and recent improvements towards molecular authentication of human cell lines
    • Romano P, Manniello A, Aresu O, Armento M, Cesaro M, Parodi B. Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines. Nucleic Acids Res 2009;37:D925-32.
    • (2009) Nucleic Acids Res , vol.37
    • Romano, P.1    Manniello, A.2    Aresu, O.3    Armento, M.4    Cesaro, M.5    Parodi, B.6
  • 12
    • 33845285906 scopus 로고    scopus 로고
    • A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia
    • DOI 10.1158/0008-5472.CAN-06-1216
    • Chen R, Gandhi V, Plunkett W. A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia. Cancer Res 2006;66:10959-66. (Pubitemid 44876995)
    • (2006) Cancer Research , vol.66 , Issue.22 , pp. 10959-10966
    • Chen, R.1    Gandhi, V.2    Plunkett, W.3
  • 13
    • 27144434812 scopus 로고    scopus 로고
    • Transcription inhibition by flavopiridol: Mechanism of chronic lymphocytic leukemia cell death
    • DOI 10.1182/blood-2005-04-1678
    • Chen R, Keating MJ, Gandhi V, Plunkett W. Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death. Blood 2005;106:2513-9. (Pubitemid 41510827)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2513-2519
    • Chen, R.1    Keating, M.J.2    Gandhi, V.3    Plunkett, W.4
  • 14
    • 14844285335 scopus 로고    scopus 로고
    • Genome-wide array-based CGH for mantle cell lymphoma: Identification of homozygous deletions of the proapoptotic gene BIM
    • DOI 10.1038/sj.onc.1208300
    • Tagawa H, Karnan S, Suzuki R, et al. Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. Oncogene 2005;24:1348-58. (Pubitemid 40343115)
    • (2005) Oncogene , vol.24 , Issue.8 , pp. 1348-1358
    • Tagawa, H.1    Karnan, S.2    Suzuki, R.3    Matsuo, K.4    Zhang, X.5    Ota, A.6    Morishima, Y.7    Nakamura, S.8    Seto, M.9
  • 15
    • 30144442233 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
    • DOI 10.1182/blood-2005-05-2091
    • Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E, Colomer D. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood 2006;107:257-64. (Pubitemid 43053550)
    • (2006) Blood , vol.107 , Issue.1 , pp. 257-264
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Montserrat, E.4    Campo, E.5    Colomer, D.6
  • 16
    • 0032031417 scopus 로고    scopus 로고
    • The caspase-RB connection in cell death
    • Tan X, Wang JY. The caspase-RB connection in cell death. Trends Cell Biol 1998;8:116-20.
    • (1998) Trends Cell Biol , vol.8 , pp. 116-120
    • Tan, X.1    Wang, J.Y.2
  • 18
    • 33748117395 scopus 로고    scopus 로고
    • Induction of apoptosis and down regulation of cell cycle proteins in mantle cell lymphoma by flavopiridol treatment
    • DOI 10.1016/j.leukres.2006.03.004, PII S014521260600107X
    • Venkataraman G, Maududi T, Ozpuyan F, et al. Induction of apoptosis and down regulation of cell cycle proteins in mantle cell lymphoma by flavopiridol treatment. Leuk Res 2006;30:1377-84. (Pubitemid 44307323)
    • (2006) Leukemia Research , vol.30 , Issue.11 , pp. 1377-1384
    • Venkataraman, G.1    Maududi, T.2    OzPuyan, F.3    Bahar, H.I.4    Izban, K.F.5    Qin, J.-Z.6    Alkan, S.7
  • 19
    • 0028274940 scopus 로고
    • Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene
    • Bodrug SE, Warner BJ, Bath ML, Lindeman GJ, Harris AW, Adams JM. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 1994;13:2124-30.
    • (1994) EMBO J , vol.13 , pp. 2124-2130
    • Bodrug, S.E.1    Warner, B.J.2    Bath, M.L.3    Lindeman, G.J.4    Harris, A.W.5    Adams, J.M.6
  • 20
    • 0028049592 scopus 로고
    • Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice
    • Lovec H, Grzeschiczek A, Kowalski MB, Moroy T. Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 1994;13:3487-95. (Pubitemid 24246185)
    • (1994) EMBO Journal , vol.13 , Issue.15 , pp. 3487-3495
    • Lovec, H.1    Grzeschiczek, A.2    Kowalski, M.-B.3    Moroy, T.4
  • 21
    • 56249117299 scopus 로고    scopus 로고
    • Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2
    • Klier M, Anastasov N, Hermann A, et al. Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2. Leukemia 2008;22:2097-105.
    • (2008) Leukemia , vol.22 , pp. 2097-2105
    • Klier, M.1    Anastasov, N.2    Hermann, A.3
  • 22
    • 0037207516 scopus 로고    scopus 로고
    • Expression of McI-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression
    • DOI 10.1002/path.1254
    • Khoury JD, Medeiros LJ, Rassidakis GZ, McDonnell TJ, Abruzzo LV, Lai R. Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression. J Pathol 2003;199:90-7. (Pubitemid 36054733)
    • (2003) Journal of Pathology , vol.199 , Issue.1 , pp. 90-97
    • Khoury, J.D.1    Medeiros, L.J.2    Rassidakis, G.Z.3    McDonnell, T.J.4    Abruzzo, L.V.5    Lai, R.6
  • 23
    • 7344236837 scopus 로고    scopus 로고
    • Establishment and characterization of a mantle cell lymphoma cell line
    • DOI 10.1046/j.1365-2141.1998.00911.x
    • Jeon HJ, Kim CW, Yoshino T, Akagi T. Establishment and characterization of a mantle cell lymphoma cell line. Br J Haematol 1998;102:1323-6. (Pubitemid 28435219)
    • (1998) British Journal of Haematology , vol.102 , Issue.5 , pp. 1323-1326
    • Jeon, H.O.J.1    Kim, C.W.2    Yoshino, T.3    Akagi, T.4
  • 26
    • 33845659888 scopus 로고    scopus 로고
    • Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: Application in mantle cell lymphoma
    • Pscherer A, Schliwka J, Wildenberger K, et al. Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphoma. FASEB J 2006;20:1188-90.
    • (2006) FASEB J , vol.20 , pp. 1188-1190
    • Pscherer, A.1    Schliwka, J.2    Wildenberger, K.3
  • 27
    • 0035055595 scopus 로고    scopus 로고
    • Mechanisms of action of flavopiridol
    • Sedlacek HH. Mechanisms of action of flavopiridol. Crit Rev Oncol Hematol 2001;38:139-70.
    • (2001) Crit Rev Oncol Hematol , vol.38 , pp. 139-170
    • Sedlacek, H.H.1
  • 29
    • 25444502962 scopus 로고    scopus 로고
    • In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas
    • Lacrima K, Valentini A, Lambertini C, et al. In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas. Ann Oncol 2005;16:1169-76.
    • (2005) Ann Oncol , vol.16 , pp. 1169-1176
    • Lacrima, K.1    Valentini, A.2    Lambertini, C.3
  • 30
    • 0035368020 scopus 로고    scopus 로고
    • Distinct roles for extracellular-signal-regulated protein kinase (ERK) mitogen-activated protein kinases and phosphatidylinositol 3-kinase in the regulation of Mcl-1 synthesis
    • DOI 10.1042/0264-6021:3560473
    • Schubert KM, Duronio V. Distinct roles for extracellular-signal-regulated protein kinase (ERK) mitogen-activated protein kinases and phosphatidylinositol 3-kinase in the regulation of Mcl-1 synthesis. Biochem J 2001;356:473-80. (Pubitemid 32532358)
    • (2001) Biochemical Journal , vol.356 , Issue.2 , pp. 473-480
    • Schubert, K.M.1    Duronio, V.2
  • 31
    • 0028965578 scopus 로고
    • The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2
    • Yang T, Kozopas KM, Craig RW. The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2. J Cell Biol 1995;128:1173-84.
    • (1995) J Cell Biol , vol.128 , pp. 1173-1184
    • Yang, T.1    Kozopas, K.M.2    Craig, R.W.3
  • 33
    • 33847415945 scopus 로고    scopus 로고
    • The rGel/BLyS fusion toxin specifically targets malignant B cells expressing the BLyS receptors BAFF-R, TACI, BCMA
    • Lyu MA, Cheung LH, Hittelman WN, Marks JW, Aguiar RC, Rosenblum MG. The rGel/BLyS fusion toxin specifically targets malignant B cells expressing the BLyS receptors BAFF-R, TACI, BCMA. Mol Cancer Ther 2007;6:460-70.
    • (2007) Mol Cancer Ther , vol.6 , pp. 460-470
    • Lyu, M.A.1    Cheung, L.H.2    Hittelman, W.N.3    Marks, J.W.4    Aguiar, R.C.5    Rosenblum, M.G.6
  • 34
    • 67349260439 scopus 로고    scopus 로고
    • U2504 determines the species specificity of the A-site cleft antibiotics: The structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome
    • Gurel G, Blaha G, Moore PB, Steitz TA. U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J Mol Biol 2009;389:146-56.
    • (2009) J Mol Biol , vol.389 , pp. 146-156
    • Gurel, G.1    Blaha, G.2    Moore, P.B.3    Steitz, T.A.4
  • 35
    • 55049088474 scopus 로고    scopus 로고
    • Homoharringtonine inhibits the AKT pathway and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells
    • Meng H, Yang C, Jin J, Zhou Y, Qian W. Homoharringtonine inhibits the AKT pathway and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells. Leuk Lymphoma 2008;49:1954-62.
    • (2008) Leuk Lymphoma , vol.49 , pp. 1954-1962
    • Meng, H.1    Yang, C.2    Jin, J.3    Zhou, Y.4    Qian, W.5
  • 36
    • 27144455334 scopus 로고    scopus 로고
    • Inhibition of the mammalian target of rapamycin and the induction of cell cycle arrest in mantle cell lymphoma cells
    • Hipp S, Ringshausen I, Oelsner M, Bogner C, Peschel C, Decker T. Inhibition of the mammalian target of rapamycin and the induction of cell cycle arrest in mantle cell lymphoma cells. Haematologica 2005;90:1433-4. (Pubitemid 41503659)
    • (2005) Haematologica , vol.90 , Issue.10 , pp. 1433-1434
    • Hipp, S.1    Ringshausen, I.2    Oelsner, M.3    Bogner, C.4    Peschel, C.5    Decker, T.6
  • 37
    • 33846516354 scopus 로고    scopus 로고
    • Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma
    • DOI 10.1038/sj.leu.2404471, PII 2404471
    • Haritunians T, Mori A, O'Kelly J, Luong QT, Giles FJ, Koeffler HP. Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma. Leukemia 2007;21:333-9. (Pubitemid 46158128)
    • (2007) Leukemia , vol.21 , Issue.2 , pp. 333-339
    • Haritunians, T.1    Mori, A.2    O'Kelly, J.3    Luong, Q.T.4    Giles, F.J.5    Koeffler, H.P.6
  • 38
    • 49049087320 scopus 로고    scopus 로고
    • Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: A phase 2 trial in the North Central Cancer Treatment Group
    • Ansell SM, Inwards DJ, Rowland KM, Jr., et al. Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. Cancer 2008;113:508-14.
    • (2008) Cancer , vol.113 , pp. 508-514
    • Ansell, S.M.1    Inwards, D.J.2    Rowland Jr., K.M.3
  • 39
    • 67650777303 scopus 로고    scopus 로고
    • Development of cell-cycle inhibitors for cancer therapy
    • Dickson MA, Schwartz GK. Development of cell-cycle inhibitors for cancer therapy. Curr Oncol 2009;16:36-43.
    • (2009) Curr Oncol , vol.16 , pp. 36-43
    • Dickson, M.A.1    Schwartz, G.K.2
  • 40
    • 77955752225 scopus 로고    scopus 로고
    • Strategy to induce apoptosis and circumvent resistance in chronic lymphocytic leukaemia
    • Chen R, Plunkett W. Strategy to induce apoptosis and circumvent resistance in chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 2010;23:155-66.
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 155-166
    • Chen, R.1    Plunkett, W.2


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