Effect of culture temperature on TNFR-Fc productivity in recombinant glutamine synthetase-chinese hamster ovary cells

Biotechnology Letters

Volumn 32, Issue 9, 2010, Pages 1239-1244

  Fan, Li ^a   Zhao, Liang ^a   Ye, Zhaoyang ^a   Sun, Yating ^a   Kou, Tianci ^a   Zhou, Yan ^a   Tan, Wen Song ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CHO cells; Culture temperature; Specific productivity; TNFR Fc

Indexed keywords

BATCH CULTIVATION; CELL DENSITY; CHINESE HAMSTER OVARY CELLS; CHO CELL; CULTURE TEMPERATURE; GLUTAMINE SYNTHETASE; PROCESS DEVELOPMENT; RECOMBINANT PROTEIN; SPECIFIC PRODUCTIVITY; TNFR-FC; VIABLE CELLS;

AMINO ACIDS; PRODUCTIVITY; PROTEINS; TRANSCRIPTION;

CELL CULTURE;

GLUTAMATE AMMONIA LIGASE; HYBRID PROTEIN; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; TNFR FC FUSION PROTEIN; TNFR-FC FUSION PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL; ARTICLE; BIOTECHNOLOGY; CHO CELL; CRICETULUS; CULTURE TECHNIQUE; HAMSTER; HUMAN; METABOLISM; METHODOLOGY; PHARMACEUTICS; TEMPERATURE;

ANIMALS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; CRICETULUS; GLUTAMATE-AMMONIA LIGASE; HUMANS; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENTS; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT FUSION PROTEINS; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

CRICETULUS GRISEUS;

EID: 77955717808     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-010-0318-5     Document Type: Article

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