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Volumn 130, Issue 9, 2010, Pages 2269-2276

A p38MAPK/HIF-1 pathway initiated by UVB irradiation is required to induce noxa and apoptosis of human keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN MCL 1; PROTEIN NOXA;

EID: 77955717085     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.93     Document Type: Article
Times cited : (40)

References (39)
  • 1
    • 14644416024 scopus 로고    scopus 로고
    • Photochemoprevention of ultraviolet B signaling and photocarcinogenesis
    • Afaq F, Adhami VM, Mukhtar H (2005) Photochemoprevention of ultraviolet B signaling and photocarcinogenesis. Mutat Res 571:153-173
    • (2005) Mutat Res , vol.571 , pp. 153-173
    • Afaq, F.1    Adhami, V.M.2    Mukhtar, H.3
  • 2
    • 22144490885 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced apoptosis in keratinocytes: On the role of cytosolic factors
    • Assefa Z, Van Laethem A, Garmyn M et al. (2005) Ultraviolet radiation-induced apoptosis in keratinocytes: on the role of cytosolic factors. Biochim Biophys Acta 1755:90-106
    • (2005) Biochim Biophys Acta , vol.1755 , pp. 90-106
    • Assefa, Z.1    Van Laethem, A.2    Garmyn, M.3
  • 4
    • 4744373426 scopus 로고    scopus 로고
    • Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389
    • Bruins W, Zwart E, Attardi LD et al. (2004) Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389. Mol Cell Biol 24:8884-8894
    • (2004) Mol Cell Biol , vol.24 , pp. 8884-8894
    • Bruins, W.1    Zwart, E.2    Attardi, L.D.3
  • 5
    • 24044494290 scopus 로고    scopus 로고
    • Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
    • Chaturvedi V, Sitailo LA, Qin JZ et al. (2005) Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 24:5299-5312
    • (2005) Oncogene , vol.24 , pp. 5299-5312
    • Chaturvedi, V.1    Sitailo, L.A.2    Qin, J.Z.3
  • 6
    • 0031586030 scopus 로고    scopus 로고
    • Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells
    • Courtois SJ, Woodworth CD, Degreef H et al. (1997) Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells. Exp Cell Res 233:135-144
    • (1997) Exp Cell Res , vol.233 , pp. 135-144
    • Courtois, S.J.1    Woodworth, C.D.2    Degreef, H.3
  • 7
    • 0035472223 scopus 로고    scopus 로고
    • UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer
    • de Gruijl FR, van Kranen HJ, Mullenders LH (2001) UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B 63:19-27
    • (2001) J Photochem Photobiol B , vol.63 , pp. 19-27
    • De Gruijl, F.R.1    Van Kranen, H.J.2    Mullenders, L.H.3
  • 8
    • 59849127984 scopus 로고    scopus 로고
    • Hypoxia regulates inflammatory gene expression in endothelial cells
    • Flamant L, Toffoli S, Raes M et al. (2009) Hypoxia regulates inflammatory gene expression in endothelial cells. Exp Cell Res 315:733-747
    • (2009) Exp Cell Res , vol.315 , pp. 733-747
    • Flamant, L.1    Toffoli, S.2    Raes, M.3
  • 9
    • 0036892018 scopus 로고    scopus 로고
    • Complex transcriptional effects of p63 isoforms: Identification of novel activation and repression domains
    • Ghioni P, Bolognese F, Duijf PH et al. (2002) Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol Cell Biol 22:8659-8668
    • (2002) Mol Cell Biol , vol.22 , pp. 8659-8668
    • Ghioni, P.1    Bolognese, F.2    Duijf, P.H.3
  • 10
    • 0020573584 scopus 로고
    • In vitro assessment of keratinocyte aging
    • Gilchrest BA (1983) In vitro assessment of keratinocyte aging. J Invest Dermatol 81:184s-9s
    • (1983) J Invest Dermatol , vol.81
    • Gilchrest, B.A.1
  • 11
    • 20444430478 scopus 로고    scopus 로고
    • Apoptotic pathways: Ten minutes to dead
    • Green DR (2005) Apoptotic pathways: ten minutes to dead. Cell 121:671-674
    • (2005) Cell , vol.121 , pp. 671-674
    • Green, D.R.1
  • 12
    • 0034795822 scopus 로고    scopus 로고
    • Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53
    • Grossman D, Kim PJ, Blanc-Brude OP et al. (2001) Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J Clin Invest 108:991-999
    • (2001) J Clin Invest , vol.108 , pp. 991-999
    • Grossman, D.1    Kim, P.J.2    Blanc-Brude, O.P.3
  • 13
    • 34447515353 scopus 로고    scopus 로고
    • Functional linkage between NOXA and Bim in mitochondrial apoptotic events
    • Han J, Goldstein LA, Hou W et al. (2007) Functional linkage between NOXA and Bim in mitochondrial apoptotic events. J Biol Chem 282:16223-16231
    • (2007) J Biol Chem , vol.282 , pp. 16223-16231
    • Han, J.1    Goldstein, L.A.2    Hou, W.3
  • 14
    • 38949158000 scopus 로고    scopus 로고
    • Supreme EnLIGHTenment: Damage recognition and signaling in the mammalian UV response
    • Herrlich P, Karin M, Weiss C (2008) Supreme EnLIGHTenment: damage recognition and signaling in the mammalian UV response. Mol Cell 29:279-290
    • (2008) Mol Cell , vol.29 , pp. 279-290
    • Herrlich, P.1    Karin, M.2    Weiss, C.3
  • 15
    • 33847271089 scopus 로고    scopus 로고
    • Coping with stress: Multiple ways to activate p53
    • Horn HF, Vousden KH (2007) Coping with stress: multiple ways to activate p53. Oncogene 26:1306-1316
    • (2007) Oncogene , vol.26 , pp. 1306-1316
    • Horn, H.F.1    Vousden, K.H.2
  • 16
    • 33845916778 scopus 로고    scopus 로고
    • Regulation of the ring finger E3 ligase Siah2 by p38 MAPK
    • Khurana A, Nakayama K, Williams S et al. (2006) Regulation of the ring finger E3 ligase Siah2 by p38 MAPK. J Biol Chem 281:35316-35326
    • (2006) J Biol Chem , vol.281 , pp. 35316-35326
    • Khurana, A.1    Nakayama, K.2    Williams, S.3
  • 17
    • 0346655211 scopus 로고    scopus 로고
    • BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
    • Kim JY, Ahn HJ, Ryu JH et al. (2004) BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J Exp Med 199:113-124
    • (2004) J Exp Med , vol.199 , pp. 113-124
    • Kim, J.Y.1    Ahn, H.J.2    Ryu, J.H.3
  • 18
    • 0043091971 scopus 로고    scopus 로고
    • BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
    • Kothari S, Cizeau J, Millan-Ward E et al. (2003) BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22:4734-4744
    • (2003) Oncogene , vol.22 , pp. 4734-4744
    • Kothari, S.1    Cizeau, J.2    Millan-Ward, E.3
  • 19
    • 0036711208 scopus 로고    scopus 로고
    • Independent contribution of three different pathways to ultraviolet-B-induced apoptosis
    • Kulms D, Schwarz T (2002) Independent contribution of three different pathways to ultraviolet-B-induced apoptosis. Biochem Pharmacol 64:837-841
    • (2002) Biochem Pharmacol , vol.64 , pp. 837-841
    • Kulms, D.1    Schwarz, T.2
  • 20
    • 27744605175 scopus 로고    scopus 로고
    • Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells
    • Kwon SJ, Song JJ, Lee YJ (2005) Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells. Clin Cancer Res 11:7607-7613
    • (2005) Clin Cancer Res , vol.11 , pp. 7607-7613
    • Kwon, S.J.1    Song, J.J.2    Lee, Y.J.3
  • 21
    • 68249106060 scopus 로고    scopus 로고
    • BH3-only proteins in apoptosis and beyond: An overview
    • Lomonosova E, Chinnadurai G (2008) BH3-only proteins in apoptosis and beyond: an overview. Oncogene 27(Suppl 1):S2-19
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Lomonosova, E.1    Chinnadurai, G.2
  • 22
    • 42449147521 scopus 로고    scopus 로고
    • The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response
    • Mandinova A, Lefort K, Tommasi di Vignano A et al. (2008) The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response. EMBO J 27:1243-1254
    • (2008) EMBO J , vol.27 , pp. 1243-1254
    • Mandinova, A.1    Lefort, K.2    Tommasi Di Vignano, A.3
  • 23
    • 44049095767 scopus 로고    scopus 로고
    • In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
    • Michalak EM, Villunger A, Adams JM et al. (2008) In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 15:1019-1029
    • (2008) Cell Death Differ , vol.15 , pp. 1019-1029
    • Michalak, E.M.1    Villunger, A.2    Adams, J.M.3
  • 24
    • 33846997899 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
    • Naik E, Michalak EM, Villunger A et al. (2007) Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. J Cell Biol 176:415-424
    • (2007) J Cell Biol , vol.176 , pp. 415-424
    • Naik, E.1    Michalak, E.M.2    Villunger, A.3
  • 25
    • 0036707398 scopus 로고    scopus 로고
    • Is HIF-1alpha a pro-or an anti-apoptotic protein?
    • Piret JP, Mottet D, Raes M et al. (2002) Is HIF-1alpha a pro-or an anti-apoptotic protein? Biochem Pharmacol 64:889-892
    • (2002) Biochem Pharmacol , vol.64 , pp. 889-892
    • Piret, J.P.1    Mottet, D.2    Raes, M.3
  • 26
    • 68149153007 scopus 로고    scopus 로고
    • Noxa: At the tip of the balance between life and death
    • Ploner C, Kofler R, Villunger A (2008) Noxa: at the tip of the balance between life and death. Oncogene 27(Suppl 1):S84-92
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Ploner, C.1    Kofler, R.2    Villunger, A.3
  • 27
    • 33750622643 scopus 로고    scopus 로고
    • Redox regulation of the hypoxia-inducible factor
    • Pouyssegur J, Mechta-Grigoriou F (2006) Redox regulation of the hypoxia-inducible factor. Biol Chem 387:1337-1346
    • (2006) Biol Chem , vol.387 , pp. 1337-1346
    • Pouyssegur, J.1    Mechta-Grigoriou, F.2
  • 28
    • 0036796888 scopus 로고    scopus 로고
    • P63 expression in normal skin and usual cutaneous carcinomas
    • Reis-Filho JS, Torio B, Albergaria A et al. (2002) p63 expression in normal skin and usual cutaneous carcinomas. J Cutan Pathol 29:517-523
    • (2002) J Cutan Pathol , vol.29 , pp. 517-523
    • Reis-Filho, J.S.1    Torio, B.2    Albergaria, A.3
  • 29
    • 34447523460 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure
    • Rezvani HR, Dedieu S, North S et al. (2007) Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure. J Biol Chem 282:16413-16422
    • (2007) J Biol Chem , vol.282 , pp. 16413-16422
    • Rezvani, H.R.1    Dedieu, S.2    North, S.3
  • 30
    • 35148828429 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HIF-1) pathway
    • Semenza GL (2007) Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007:cm8
    • (2007) Sci STKE 2007
    • Semenza, G.L.1
  • 31
    • 0032897552 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells
    • Shimizu H, Banno Y, Sumi N et al. (1999) Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells. J Invest Dermatol 112:769-774
    • (1999) J Invest Dermatol , vol.112 , pp. 769-774
    • Shimizu, H.1    Banno, Y.2    Sumi, N.3
  • 32
    • 67349117381 scopus 로고    scopus 로고
    • Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation
    • Sitailo LA, Jerome-Morais A, Denning MF (2009) Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation. J Invest Dermatol 129:1351-1360
    • (2009) J Invest Dermatol , vol.129 , pp. 1351-1360
    • Sitailo, L.A.1    Jerome-Morais, A.2    Denning, M.F.3
  • 33
    • 0037205401 scopus 로고    scopus 로고
    • Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes
    • Sitailo LA, Tibudan SS, Denning MF (2002) Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J Biol Chem 277:19346-19352
    • (2002) J Biol Chem , vol.277 , pp. 19346-19352
    • Sitailo, L.A.1    Tibudan, S.S.2    Denning, M.F.3
  • 34
    • 0035497646 scopus 로고    scopus 로고
    • In vitro and in vivo transfer of bcl-2 gene into keratinocytes suppresses UVB-induced apoptosis
    • Takahashi H, Honma M, Ishida-Yamamoto A et al. (2001) In vitro and in vivo transfer of bcl-2 gene into keratinocytes suppresses UVB-induced apoptosis. Photochem Photobiol 74:579-586
    • (2001) Photochem Photobiol , vol.74 , pp. 579-586
    • Takahashi, H.1    Honma, M.2    Ishida-Yamamoto, A.3
  • 35
    • 33749048083 scopus 로고    scopus 로고
    • Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes
    • Van Laethem A, Nys K, Van Kelst S et al. (2006) Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes. Free Radic Biol Med 41:1361-1371
    • (2006) Free Radic Biol Med , vol.41 , pp. 1361-1371
    • Van Laethem, A.1    Nys, K.2    Van Kelst, S.3
  • 36
    • 10044219516 scopus 로고    scopus 로고
    • Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes
    • Van Laethem A, Van Kelst S, Lippens S et al. (2004) Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes. FASEB J 18:1946-1948
    • (2004) FASEB J , vol.18 , pp. 1946-1948
    • Van Laethem, A.1    Van Kelst, S.2    Lippens, S.3
  • 37
    • 0242410719 scopus 로고    scopus 로고
    • P53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
    • Villunger A, Michalak EM, Coultas L et al. (2003) p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302:1036-1038
    • (2003) Science , vol.302 , pp. 1036-1038
    • Villunger, A.1    Michalak, E.M.2    Coultas, L.3
  • 38
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9:47-59
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 39
    • 0028596185 scopus 로고
    • Sunburn and p53 in the onset of skin cancer
    • Ziegler A, Jonason AS, Leffell DJ et al. (1994) Sunburn and p53 in the onset of skin cancer. Nature 372:773-776
    • (1994) Nature , vol.372 , pp. 773-776
    • Ziegler, A.1    Jonason, A.S.2    Leffell, D.J.3


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