-
1
-
-
14644416024
-
Photochemoprevention of ultraviolet B signaling and photocarcinogenesis
-
Afaq F, Adhami VM, Mukhtar H (2005) Photochemoprevention of ultraviolet B signaling and photocarcinogenesis. Mutat Res 571:153-173
-
(2005)
Mutat Res
, vol.571
, pp. 153-173
-
-
Afaq, F.1
Adhami, V.M.2
Mukhtar, H.3
-
2
-
-
22144490885
-
Ultraviolet radiation-induced apoptosis in keratinocytes: On the role of cytosolic factors
-
Assefa Z, Van Laethem A, Garmyn M et al. (2005) Ultraviolet radiation-induced apoptosis in keratinocytes: on the role of cytosolic factors. Biochim Biophys Acta 1755:90-106
-
(2005)
Biochim Biophys Acta
, vol.1755
, pp. 90-106
-
-
Assefa, Z.1
Van Laethem, A.2
Garmyn, M.3
-
4
-
-
4744373426
-
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389
-
Bruins W, Zwart E, Attardi LD et al. (2004) Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389. Mol Cell Biol 24:8884-8894
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8884-8894
-
-
Bruins, W.1
Zwart, E.2
Attardi, L.D.3
-
5
-
-
24044494290
-
Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
-
Chaturvedi V, Sitailo LA, Qin JZ et al. (2005) Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 24:5299-5312
-
(2005)
Oncogene
, vol.24
, pp. 5299-5312
-
-
Chaturvedi, V.1
Sitailo, L.A.2
Qin, J.Z.3
-
6
-
-
0031586030
-
Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells
-
Courtois SJ, Woodworth CD, Degreef H et al. (1997) Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells. Exp Cell Res 233:135-144
-
(1997)
Exp Cell Res
, vol.233
, pp. 135-144
-
-
Courtois, S.J.1
Woodworth, C.D.2
Degreef, H.3
-
7
-
-
0035472223
-
UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer
-
de Gruijl FR, van Kranen HJ, Mullenders LH (2001) UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B 63:19-27
-
(2001)
J Photochem Photobiol B
, vol.63
, pp. 19-27
-
-
De Gruijl, F.R.1
Van Kranen, H.J.2
Mullenders, L.H.3
-
8
-
-
59849127984
-
Hypoxia regulates inflammatory gene expression in endothelial cells
-
Flamant L, Toffoli S, Raes M et al. (2009) Hypoxia regulates inflammatory gene expression in endothelial cells. Exp Cell Res 315:733-747
-
(2009)
Exp Cell Res
, vol.315
, pp. 733-747
-
-
Flamant, L.1
Toffoli, S.2
Raes, M.3
-
9
-
-
0036892018
-
Complex transcriptional effects of p63 isoforms: Identification of novel activation and repression domains
-
Ghioni P, Bolognese F, Duijf PH et al. (2002) Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol Cell Biol 22:8659-8668
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8659-8668
-
-
Ghioni, P.1
Bolognese, F.2
Duijf, P.H.3
-
10
-
-
0020573584
-
In vitro assessment of keratinocyte aging
-
Gilchrest BA (1983) In vitro assessment of keratinocyte aging. J Invest Dermatol 81:184s-9s
-
(1983)
J Invest Dermatol
, vol.81
-
-
Gilchrest, B.A.1
-
11
-
-
20444430478
-
Apoptotic pathways: Ten minutes to dead
-
Green DR (2005) Apoptotic pathways: ten minutes to dead. Cell 121:671-674
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
12
-
-
0034795822
-
Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53
-
Grossman D, Kim PJ, Blanc-Brude OP et al. (2001) Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J Clin Invest 108:991-999
-
(2001)
J Clin Invest
, vol.108
, pp. 991-999
-
-
Grossman, D.1
Kim, P.J.2
Blanc-Brude, O.P.3
-
13
-
-
34447515353
-
Functional linkage between NOXA and Bim in mitochondrial apoptotic events
-
Han J, Goldstein LA, Hou W et al. (2007) Functional linkage between NOXA and Bim in mitochondrial apoptotic events. J Biol Chem 282:16223-16231
-
(2007)
J Biol Chem
, vol.282
, pp. 16223-16231
-
-
Han, J.1
Goldstein, L.A.2
Hou, W.3
-
14
-
-
38949158000
-
Supreme EnLIGHTenment: Damage recognition and signaling in the mammalian UV response
-
Herrlich P, Karin M, Weiss C (2008) Supreme EnLIGHTenment: damage recognition and signaling in the mammalian UV response. Mol Cell 29:279-290
-
(2008)
Mol Cell
, vol.29
, pp. 279-290
-
-
Herrlich, P.1
Karin, M.2
Weiss, C.3
-
15
-
-
33847271089
-
Coping with stress: Multiple ways to activate p53
-
Horn HF, Vousden KH (2007) Coping with stress: multiple ways to activate p53. Oncogene 26:1306-1316
-
(2007)
Oncogene
, vol.26
, pp. 1306-1316
-
-
Horn, H.F.1
Vousden, K.H.2
-
16
-
-
33845916778
-
Regulation of the ring finger E3 ligase Siah2 by p38 MAPK
-
Khurana A, Nakayama K, Williams S et al. (2006) Regulation of the ring finger E3 ligase Siah2 by p38 MAPK. J Biol Chem 281:35316-35326
-
(2006)
J Biol Chem
, vol.281
, pp. 35316-35326
-
-
Khurana, A.1
Nakayama, K.2
Williams, S.3
-
17
-
-
0346655211
-
BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
-
Kim JY, Ahn HJ, Ryu JH et al. (2004) BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J Exp Med 199:113-124
-
(2004)
J Exp Med
, vol.199
, pp. 113-124
-
-
Kim, J.Y.1
Ahn, H.J.2
Ryu, J.H.3
-
18
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
Kothari S, Cizeau J, Millan-Ward E et al. (2003) BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22:4734-4744
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
Millan-Ward, E.3
-
19
-
-
0036711208
-
Independent contribution of three different pathways to ultraviolet-B-induced apoptosis
-
Kulms D, Schwarz T (2002) Independent contribution of three different pathways to ultraviolet-B-induced apoptosis. Biochem Pharmacol 64:837-841
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 837-841
-
-
Kulms, D.1
Schwarz, T.2
-
20
-
-
27744605175
-
Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells
-
Kwon SJ, Song JJ, Lee YJ (2005) Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells. Clin Cancer Res 11:7607-7613
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7607-7613
-
-
Kwon, S.J.1
Song, J.J.2
Lee, Y.J.3
-
21
-
-
68249106060
-
BH3-only proteins in apoptosis and beyond: An overview
-
Lomonosova E, Chinnadurai G (2008) BH3-only proteins in apoptosis and beyond: an overview. Oncogene 27(Suppl 1):S2-19
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Lomonosova, E.1
Chinnadurai, G.2
-
22
-
-
42449147521
-
The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response
-
Mandinova A, Lefort K, Tommasi di Vignano A et al. (2008) The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response. EMBO J 27:1243-1254
-
(2008)
EMBO J
, vol.27
, pp. 1243-1254
-
-
Mandinova, A.1
Lefort, K.2
Tommasi Di Vignano, A.3
-
23
-
-
44049095767
-
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
-
Michalak EM, Villunger A, Adams JM et al. (2008) In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 15:1019-1029
-
(2008)
Cell Death Differ
, vol.15
, pp. 1019-1029
-
-
Michalak, E.M.1
Villunger, A.2
Adams, J.M.3
-
24
-
-
33846997899
-
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
-
Naik E, Michalak EM, Villunger A et al. (2007) Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. J Cell Biol 176:415-424
-
(2007)
J Cell Biol
, vol.176
, pp. 415-424
-
-
Naik, E.1
Michalak, E.M.2
Villunger, A.3
-
25
-
-
0036707398
-
Is HIF-1alpha a pro-or an anti-apoptotic protein?
-
Piret JP, Mottet D, Raes M et al. (2002) Is HIF-1alpha a pro-or an anti-apoptotic protein? Biochem Pharmacol 64:889-892
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 889-892
-
-
Piret, J.P.1
Mottet, D.2
Raes, M.3
-
26
-
-
68149153007
-
Noxa: At the tip of the balance between life and death
-
Ploner C, Kofler R, Villunger A (2008) Noxa: at the tip of the balance between life and death. Oncogene 27(Suppl 1):S84-92
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Ploner, C.1
Kofler, R.2
Villunger, A.3
-
27
-
-
33750622643
-
Redox regulation of the hypoxia-inducible factor
-
Pouyssegur J, Mechta-Grigoriou F (2006) Redox regulation of the hypoxia-inducible factor. Biol Chem 387:1337-1346
-
(2006)
Biol Chem
, vol.387
, pp. 1337-1346
-
-
Pouyssegur, J.1
Mechta-Grigoriou, F.2
-
28
-
-
0036796888
-
P63 expression in normal skin and usual cutaneous carcinomas
-
Reis-Filho JS, Torio B, Albergaria A et al. (2002) p63 expression in normal skin and usual cutaneous carcinomas. J Cutan Pathol 29:517-523
-
(2002)
J Cutan Pathol
, vol.29
, pp. 517-523
-
-
Reis-Filho, J.S.1
Torio, B.2
Albergaria, A.3
-
29
-
-
34447523460
-
Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure
-
Rezvani HR, Dedieu S, North S et al. (2007) Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure. J Biol Chem 282:16413-16422
-
(2007)
J Biol Chem
, vol.282
, pp. 16413-16422
-
-
Rezvani, H.R.1
Dedieu, S.2
North, S.3
-
30
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza GL (2007) Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007:cm8
-
(2007)
Sci STKE 2007
-
-
Semenza, G.L.1
-
31
-
-
0032897552
-
Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells
-
Shimizu H, Banno Y, Sumi N et al. (1999) Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells. J Invest Dermatol 112:769-774
-
(1999)
J Invest Dermatol
, vol.112
, pp. 769-774
-
-
Shimizu, H.1
Banno, Y.2
Sumi, N.3
-
32
-
-
67349117381
-
Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation
-
Sitailo LA, Jerome-Morais A, Denning MF (2009) Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation. J Invest Dermatol 129:1351-1360
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1351-1360
-
-
Sitailo, L.A.1
Jerome-Morais, A.2
Denning, M.F.3
-
33
-
-
0037205401
-
Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes
-
Sitailo LA, Tibudan SS, Denning MF (2002) Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J Biol Chem 277:19346-19352
-
(2002)
J Biol Chem
, vol.277
, pp. 19346-19352
-
-
Sitailo, L.A.1
Tibudan, S.S.2
Denning, M.F.3
-
34
-
-
0035497646
-
In vitro and in vivo transfer of bcl-2 gene into keratinocytes suppresses UVB-induced apoptosis
-
Takahashi H, Honma M, Ishida-Yamamoto A et al. (2001) In vitro and in vivo transfer of bcl-2 gene into keratinocytes suppresses UVB-induced apoptosis. Photochem Photobiol 74:579-586
-
(2001)
Photochem Photobiol
, vol.74
, pp. 579-586
-
-
Takahashi, H.1
Honma, M.2
Ishida-Yamamoto, A.3
-
35
-
-
33749048083
-
Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes
-
Van Laethem A, Nys K, Van Kelst S et al. (2006) Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes. Free Radic Biol Med 41:1361-1371
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1361-1371
-
-
Van Laethem, A.1
Nys, K.2
Van Kelst, S.3
-
36
-
-
10044219516
-
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes
-
Van Laethem A, Van Kelst S, Lippens S et al. (2004) Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes. FASEB J 18:1946-1948
-
(2004)
FASEB J
, vol.18
, pp. 1946-1948
-
-
Van Laethem, A.1
Van Kelst, S.2
Lippens, S.3
-
37
-
-
0242410719
-
P53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L et al. (2003) p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302:1036-1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
-
38
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9:47-59
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
39
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason AS, Leffell DJ et al. (1994) Sunburn and p53 in the onset of skin cancer. Nature 372:773-776
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
|