Comparison of interferon-γ release assay and tuberculin test for screening in healthcare workers

Revista Portuguesa de Pneumologia

Volumn 16, Issue 2, 2010, Pages 211-221

  Costa, José Castela Torres ^a,b   Silva, Rui ^a,b   Sá, Raul ^a   Cardoso, Maria João ^a   Ribeiro, Carla ^a   Nienhaus, Albert ^c  

^a HOSPITAL DE SÃO JOÃO   (Portugal)

^b University of Porto   (Portugal)

^c Institution for Statutory Accident Insurance and Prevention in the Health and Welfare Services   (Germany)

Author keywords

Healthcare workers; Interferon release assay; Portugal; Tuberculin skin test; Tuberculosis

Indexed keywords

GAMMA INTERFERON;

ADOLESCENT; ADULT; AGED; ARTICLE; BCG VACCINATION; BIOASSAY; CYTOKINE RELEASE; FEMALE; HEALTH CARE PERSONNEL; HUMAN; INCIDENCE; INFECTION CONTROL; MAJOR CLINICAL STUDY; MALE; SCREENING; SCREENING TEST; THORAX RADIOGRAPHY; TUBERCULIN TEST; TUBERCULOSIS; COMPARATIVE STUDY; MIDDLE AGED;

ADOLESCENT; ADULT; FEMALE; HEALTH PERSONNEL; HUMANS; INFECTION CONTROL; INTERFERON-GAMMA; MALE; MIDDLE AGED; TUBERCULIN TEST; TUBERCULOSIS; YOUNG ADULT;

EID: 77955716977     PISSN: 08732159     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0873-2159(15)30022-2     Document Type: Article

References (32)

1. Saleiro S, Santos AR, Vidal O, Carvalho T, Torres Costa J, Marques JA. Tuberculosis in hospital department health care workers. Rev Port Pneumol 2007; 13(6):789-799.
2. Seidler A, Nienhaus A, Diel R. Review of epidemiological studies on the occupational risk of tuberculosis in low-incidence areas. Respiration 2005; 72(4):431-446.
3. Menzies D, Joshi R, Pai M. Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007; 11(6):593-605.
4. CDC - Center for Disease Control and Prevention. Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Healthcare Settings, 2005. MMWR 2005; 54(RR-17):1-141.
5. Menzies D. What does tuberculin reactivity after Bacille Calmette-Guerin vaccination tell us? Clin infect Dis 2000; 31(Suppl 3):S71-S74.
6. Andersen P, Munk ME, Pollock JM, Doherty TM. Specific immune-based diagnosis of tuberculosis. Lancet 2000; 356(9235):1099-1104.
7. Nahid P, Pai M, Hopewell PC. Advances in the diagnosis and treatment of tuberculosis. Proc Am Thorac Soc 2006; 3:103-110.
8. Pai M, Riley LW, Colford JM. Interferon-gamma assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infect Dis 2004; 4:761-776. (Pubitemid 39574348)
9. Menzies D, Pai M, Comstock G. Meta-analysis: New tests for the diagnosis of latent tuberculosis infection: Areas of uncertainty and recommendations for research. Ann Intern Med 2007; 146:340-352.
10. Diel R, Loddenkemper R, Meywald-Walter K, Niemann S, Nienhaus A: Predictive value of a whole blood IFN-{gamma} assay for the development of active TB disease. Am J Respir Crit Care Med 2008; 177:1164-1170.
11. Harada N, Nakajima Y, Higuchi K, Sekiya Y, Rothel J, Mori T. Screening for tuberculosis infection using whole -blood interferon-γ and Mantoux testing among Japanese healthcare workers. Infection Control and Hospital Epidemiology 2006; 27(5):442-448. (Pubitemid 43835524)
12. Soberg B, Andersen AB, Larsen HK, Weldingh K, Andersen P, Kofoerd K, Ravn P. Detecting a low prevalence of latent tuberculosis among health care workers in Denmark detected by M. tuberculosis specific INF-γ whole-blood test. Scandinavian Journal of Infectious Diseases 2007; 39:554-559. (Pubitemid 47009164)
13. Kobashi Y, Obase Y, Fukuda M, Yoshida K, Miyashita N, Fujii M, Oka M. Usefulness of QuantiFERON TB-2G, a diagnostic method for latent tuberculosis infection, in a contact investigation of health care workers. Intern Med 2007; 46(18):1543-1549. (Pubitemid 47521049)
14. Mirtskhulava V, Kempker R, Shields KL, Leonard MK, Tsertsvadze T, del Rio C, Salakaia A, Blumberg HM. Prevalence and risk factors for latent tuberculosis infection among health care workers in Georgia. Int J Tuberc Lung Dis 2008; 12(5):513-519.
15. Nienhaus A, Schablon A, Siano B, le Bacle C, Diel R. Evaluation of the interferon -gamma release assay in healthcare workers. Int Arch Occup Environ Health 2008; 81:295-300.
16. Schablon A, Beckmann G, Harling M, Diel R, Nienhaus A. Prevalence of latent tuberculosis infection among healthcare workers in a hospital for pulmonary diseases. J Occup Med Toxicol 2009; 4:1.
17. Vinton P, Mihrshahi S, Johnson P; Jenkin GA; Jolley D, Biggs BA. Comparison of QuantiFERON-TB gold in-tube test and tuberculin skin test for identification of latent Mycobacterium tuberculosis infection in healthcare staff and association between positive test results and known risk factors for infection. Infection Control and Hospital Epidemiology 2009; 30(3), online first.
18. Programa Nacional de Vacinação. Direcção-Geral de Saúde - Ministério da Saúde. Available at http://www.dgsaude.pt/upload/membro.id/ficheiros/i007442.pdf (accessed May 1st, 2009)
19. Hosmer D, Lemeshow S. Applied logistic regression. New York, NY: John Wiley & Sons 2000.
20. Farhat M, Greenaway, Pai M, Menzies D. False-positive tuberculin skin tests: what is the absolute effect of BCG and non -tuberculous mycobacteria? Int J Tuberc Lung Dis 2006; 10(11):1192-1204.
21. Nienhaus A, Schablon A, Diel R. Interferon-γ release assay for the diagnosis of latent TB infection - analysis of discordant results, when compared to the tuberculin skin test. PLoS ONE 2008; 3(7):e2665.
22. Torres Costa Torres Costa J, Sá R, Cardoso MJ, Silva R, Ferreira J, Ribeiro C, Miranda M, Plácido JL, Nienhaus A. Tuberculosis screening in Portuguese healthcare workers using the tuberculin skin test and the interferon-γ release assay. Eur Resp J 2009 (in press).
23. Diel R, Seidler A, Nienhaus A, Rusch-Gerdes S, Niemann S. Occupational risk of tuberculosis transmission in a low incidence area. Respir Res 2005; 6(1):35-45.
24. De Vries G, Sebek MM, Lambregts-van Weezenbeek CS. Health-care workers with tuberculosis infected during work. Eur Respir J 2006; 28(6): 1216-21
25. Lee S S-J, Liu Y-C, Huang T-S, Chen Y-S, Tsai H-C, Wann S-R, Lin H-H. Comparison of the interferon-γ release assay and the tuberculin skin test for contact investigation of tuberculosis in BCG-vaccinated health care workers. Scandinavian Journal of Infectious Disease 2008; 40(5): 373-380.
26. Menzies D. Interpretation of repeated tuberculin tests. Boosting, conversion, and reversion. Am J Respir Crit Care Med 1999; 159:15-21.
27. Pai M, Joshi R, Dogra S, Zwerling AA, Gajalakshmi D, Goswami K, Reddy MVR, Kalantri S, Hill PC, Menzies D, Hopewell PC. T-cell assay conversions and reversions among household contacts of tuberculosis patients in rural India Int J Tuberc Lung Dis 2009; 13(1):84-92.
28. Yoshiyama T, Harada N, Higuchi K, Nakajima Y, Ogata H. Estimation of incidence of tuberculosis infection in healthcare workers using repeated interferon-γ assays. Epidemiol Infect 2009 (ahead of print).
29. Mack U, Migliori GB, Sester M, Rieder HL, Ehlers S, Goletti D, et al, for the TBNET. LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? - A TBNET consensus statement. Eur Respir J 2009; 33: 956-973.
30. Duarte R. Teste tuberculínico. Como optimizar? Rev Port Pneumol 2009; 15 (2):295-304.
31. Duarte R, Amado J, Lucas H, Sapage JM, Comissão de Trabalho de Tuberculose da Sociedade Portuguesa de Pneumologia. Tratamento da tuberculose latente: Revisão das normas, 2006. Rev Port Pneumol 2007; 13(3): 397-418.
32. Pai M, Joshi R, Dogra S, Mendiratta DK, Narang P, Dheda K Kalantri S. Persistently elevated T cell interferon-γ response after treatment for latent tuberculosis infection among healthcare workers in India: a preliminary report. Journal of Occupational Medicine and Toxicology 2006; 1:7.