Prevalence and risk factors for latent tuberculosis infection among health care workers in Georgia

International Journal of Tuberculosis and Lung Disease

Volumn 12, Issue 5, 2008, Pages 513-519

  Mirtskhulava, Veriko ^a,b,c   Kempker, R ^b,c   Shields, K L ^b   Leonard, M K ^b   Tsertsvadze, T ^d   Del Rio, C ^b,c   Salakaia, A ^a   Blumberg, H M ^b,c  

^a National Center of Tuberculosis and Lung Diseases   (Georgia)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d AIDS and Clinical Immunology Research Center   (Georgia)

Author keywords

IFN assay; Nosocomial transmission; Tuberculin skin test; Tuberculosis infection

Indexed keywords

ADULT; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CROSS-SECTIONAL STUDY; DIAGNOSTIC TEST; EMPLOYMENT; FEMALE; GEORGIA (REPUBLIC); HEALTH CARE PERSONNEL; HUMAN; INFECTION RISK; INTERFERON GAMMA RELEASE ASSAY; KAPPA STATISTICS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; TUBERCULIN TEST; TUBERCULOSIS; TUBERCULOSIS CONTROL;

ADOLESCENT; ADULT; CROSS-SECTIONAL STUDIES; FEMALE; GEORGIA (REPUBLIC); HEALTH PERSONNEL; HUMANS; INFECTION CONTROL; INTERFERON TYPE II; LOGISTIC MODELS; MALE; MASS SCREENING; MIDDLE AGED; MULTIVARIATE ANALYSIS; OCCUPATIONAL DISEASES; PREVALENCE; REAGENT KITS, DIAGNOSTIC; RISK FACTORS; TUBERCULIN TEST; TUBERCULOSIS;

EID: 43949120134     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Fennelly M, Kevin P, Iseman D. Health care workers and tuberculosis: the battle of a century [Editorial]. Int J Tuberc Lung Dis 1999; 3: 363.
2. Joshi R, Reingold A L, Menzies D, Pai M. Tuberculosis among health care workers in low- and middle-income countries: a systematic review. PLoS Med 2006; 3: 494.
3. Harries A D, Maher D, Nunn P. Practical and affordable measures for the protection of health care workers from tuberculosis in low-income countries. Bull World Health Organ 1997; 75: 477-489.
4. Mazurek G H, Jereb J, LoBue P, Iademarco M F, Metchock B, Vernon A. Guidelines for using the Quantiferon®-TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005; 54: 49-55.
5. Blumberg H M, Watkins D L, Berschling J D, et al. Preventing the nosocomial transmission of tuberculosis. Ann Intern Med 1995; 122: 658-663.
6. Jensen P A, Lambert L A, Iademarco M F, Ridzon R. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health care settings, 2005. Report no: 54(RR17). Atlanta, GA, USA: Center for Disease Control and Prevention, 2005.
7. McGowan J E. Nosocomial tuberculosis: new progress in control and prevention. Clin Infect Dis 1995; 21: 489-505.
8. World Health Organization. Guidelines for the prevention of tuberculosis in health care facilities in resource-limited settings. WHO/TB/99.269. Geneva, Switzerland: WHO, 1999.
9. World Health Organization. Tuberculosis infection control in the era of expanding HIV care and treatment. Geneva, Switzerland: WHO, 2006. http://www.who.int/tb/publications/2006/tbhiv_infectioncontrol_addendum.pdf Accessed April 2007.
10. Jones-Lopez A C, Ellner J J. Tuberculosis infection among HCWs [Editorial]. Int J Tuberc Lung Dis 2005; 9: 591.
11. Gandhi N R, Moll A, Sturm A W, et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet 2006; 368: 1575-1580.
12. Brodie D, Schluger N W. The diagnosis of tuberculosis. Clin Chest Med 2005; 26: 247-271.
13. American Thoracic Society; Centers for Disease Control and Prevention. Targeted tuberculin testing and treatment of latent tuberculosis infection. 2000; 49 (RR-6): 1-51.
14. Blumberg H M, Leonard M K, Jasmer R M. Update on the treatment of tuberculosis and latent tuberculosis infection. JAMA 2005; 293: 2776-2784.
15. Pai M, Joshi R, Dogra S, et al. Serial testing of health care workers for tuberculosis using interferon-gamma assay. Am J Respir Crit Care Med 2006; 174: 349-355.
16. Ferrara G, Losi M, Meacci M, et al. Routine hospital use of a new commercial whole blood interferon-gamma assay for the diagnosis of tuberculosis infection. Am J Respir Crit Care Med 2005; 172: 631-635.
17. Kraemer H C. Measurement of reliability for categorical data in medical research. Stat Methods Med Res 1992; 1: 183-199.
18. Kleinbaum D G, Kupper L L, Muller K E, Nizam A. The correlation coefficient and Straight-line regression analysis. In: Applied regression analysis and other multivariable methods. 3rd ed. Pacific Grove, CA, USA: Duxbury Press, 1998: pp 88-103.
19. Kleinbaum D G, Klein M. Modeling strategy for assessing interaction and confounding. In: Kleinbaum D G, Klein M, eds. Logistic regression: a self-learning text. 2nd ed. New York, NY, USA: Springer Science+Business Media Inc, 2002: pp 191-226.
20. Kleinbaum D G, Klein M. Maximum likelihood techniques: an overview. In: Kleinbaum D G, Klein M, eds. Logistic regression: a self-learning text. 2nd ed. New York, NY, USA: Springer Science+ Business Media Inc, 2002: pp 101-124.
21. Drobniewski F, Balabanova Y, Zakamova E, Nikolayevskyy V, Fedorin I. Rates of latent tuberculosis in health care staff in Russia. PLoS Med 2007; 4: e55.
22. Pai M, Gokhale K, Joshi R, et al. Mycobacterium tuberculosis infection in health care workers in rural India: comparison of a whole-blood interferon-gamma assay with tuberculin skin testing. JAMA 2005; 293: 2746-2755.
23. Menzies D, Joshi R, Pai M. Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007; 11: 593-605.
24. Weinstock D, Hahn O, Wittkamp M, et al. Risk for tuberculosis infection among internally displaced persons in the Republic of Georgia. Int J Tuberc Lung Dis 2001; 5: 164-169.
25. Farhat M, Greenaway C, Pai M, Menzies D. False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria? Int J Tuberc Lung Dis 2006; 10: 1192-1204.