Comparison of QuantiFERON-TB gold in-tube test and tuberculin skin test for identification of latent Mycobacterium tuberculosis infection in healthcare staff and association between positive test results and known risk factors for infection

Infection Control and Hospital Epidemiology

Volumn 30, Issue 3, 2009, Pages 215-221

  Vinton, Paul ^a   Mihrshahi, Seema ^a   Johnson, Paul ^a   Jenkin, Grant A ^b   Jolley, Damien ^b   Biggs, Beverley Ann ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; GAMMA INTERFERON;

ADULT; AGED; ARTICLE; AUSTRALIA; BACTERIUM IDENTIFICATION; BCG VACCINATION; COMPARATIVE STUDY; DEMOGRAPHY; DIAGNOSTIC ACCURACY; FEMALE; HEALTH CARE PERSONNEL; HIGH RISK POPULATION; HOSPITAL PERSONNEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL STAFF; MYCOBACTERIUM TUBERCULOSIS; PREVALENCE; QUANTIFERON GOLD IN TUBE TEST; RISK FACTOR; SKIN TEST; TUBERCULIN TEST; TUBERCULOSIS;

ADULT; AGED; FEMALE; HEALTH PERSONNEL; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; REAGENT KITS, DIAGNOSTIC; RISK FACTORS; TUBERCULIN TEST; TUBERCULOSIS; YOUNG ADULT;

EID: 61849106481     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/595695     Document Type: Article

References (29)

1. Jereb JA, Klevens RM, Privett TD, et al. Tuberculosis in health care workers at a hospital with an outbreak of multidrug-resistant Mycobacterium tuberculosis. Arch Intern Med 1995; 155:854-859.
2. Menzies D, Joshi R, Pai M. Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007; 11:593-605.
3. Stuart RL, Bennett NJ, Forbes AB, Grayson ML. Assessing the risk of tuberculosis infection among healthcare workers: the Melbourne Mantoux Study. Melbourne Mantoux Study Group. Med J Aust 2001; 174:569-573.
4. Stuart RL, Grayson ML. Health care workers and tuberculosis. Aust N Z J Med 2000; 30:367-372.
5. Gandhi NR, Moll A, Sturm AW, et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet 2006; 368:1575-1580.
6. Graham M, Howley TM, Pierce RJ, Johnson PD. Should medical students be routinely offered BCG vaccination? Med J Aust 2006; 185:324-326.
7. Moran-Mendoza O, Marion SA, Elwood K, Patrick DM, FitzGerald JM. Tuberculin skin test size and risk of tuberculosis development: a large population-based study in contacts. Int J Tuberc Lung Dis 2007; 11:1014-1020.
8. Tissot F, Zanetti G, Francioli P, Zellweger JP, Zysset F. Influence of bacille Calmette-Guerin vaccination on size of tuberculin skin test reaction: to what size? Clin Infect Dis 2005; 40:211-217.
9. von Reyn CF, Horsburgh CR, Olivier KN, et al. Skin test reactions to Mycobacterium tuberculosis purified protein derivative and Mycobacterium avium sensitin among health care workers and medical students in the United States. Int J Tuberc Lung Dis 2001; 5:1122-1128.
10. Panlilio AL, Burwen DR, Curtis AB, et al. Tuberculin skin testing surveillance of health care personnel. Clin Infect Dis 2002; 35:219-227.
11. Marsh BJ, San Vicente J, von Reyn CF. Utility of dual skin tests to evaluate tuberculin skin test reactions of 10 to 14 mm in healthcare workers. Infect Control Hosp Epidemiol 2003; 24:821-824.
12. Johnson PD, Stuart RL, Grayson ML, et al. Tuberculin-purified protein derivative-, MPT-64-, and ESAT-6-stimulated gamma interferon responses in medical students before and after Mycobacterium bovis BCG vaccination and in patients with tuberculosis. Clin Diagn Lab Immunol 1999; 6:934-937.
13. Mazurek GH, Jereb J, Lobue P, Iademarco MF, Metchock B, Vernon A. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005; 54(RR-15):49-55.
14. Pai M, Riley LW, Colford JM Jr. Interferon-gamma assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infect Dis 2004; 4:761-776.
15. Nakaoka H, Lawson L, Squire SB, et al. Risk for tuberculosis among children. Emerg Infect Dis 2006; 12:1383-1388.
16. Villarino ME, Mazurek G. Tuberculosis contacts, concerns, and controls: what matters for healthcare workers? Infect Control Hosp Epidemiol 2006; 27:433-435.
17. World Health Organization. Global Tuberculosis Database 2006. Available at: http://www.who.int/globalatlas/dataQuery/default.asp. Accessed November 12, 2007.
18. Broekmans JF, Migliori GB, Rieder HL, et al. European framework for tuberculosis control and elimination in countries with a low incidence: recommendations of the World Health Organization (WHO), International Union against Tuberculosis and Lung Disease (IUATLD) and Royal Netherlands Tuberculosis Association (KNCV) Working Group. Eur Respir J 2002; 19:765-775.
19. The Australian immunisation handbook. 9th ed. Australia: National Health Medical Research Council; 2008:231-234. Available at: http: //www.immunise. health.gov.au/internet/immunise/publishing.nsf/Content/Handbook-home. Accessed January 14, 2009.
20. Department of Human Services. Management, control and prevention of tuberculosis: guidelines for health care providers (2002-2005). Available at:http://www.health.vic.gov.au/ideas/diseases/tb-mgmt-guide. Accessed January 14, 2009.
21. Farris A, Branda J. QuantiFERON-TB Gold assay for tuberculosis infection. Clin Microbiol Newsl 2007;129-136.
22. Cellestis. QuantiFERON-TB Gold IT Method and Technical Instructions. Melbourne, Australia: Cellestis; 2007. Available at: http://www.cellestis.com/ IRM/Content/aust/qtfproducts-tbgoldintube-techinfo.html. Accessed December 12, 2007.
23. Ewer K, Deeks J, Alvarez L, et al. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet 2003; 361:1168-1173.
24. Kang YA, Lee HW, Yoon HI, et al. Discrepancy between the tuberculin skin test and the whole-blood interferon gamma assay for the diagnosis of latent tuberculosis infection in an intermediate tuberculosis-burden country. JAMA 2005; 293:2756-2761.
25. Kobashi Y, Obase Y, Fukuda M, et al. Usefulness of QuantiFERON TB-2G, a diagnostic method for latent tuberculosis infection, in a contact investigation of health care workers. Intern Med (Tokyo, Japan). 2007; 46:1543-1549.
26. Pai M, Gokhale K, Joshi R, et al. Mycobacterium tuberculosis infection in health care workers in rural India: comparison of a whole-blood interferon gamma assay with tuberculin skin testing. JAMA 2005; 293:2746-2755.
27. Mazurek GH, Zajdowicz MJ, Hankinson AL, et al. Detection of Mycobacterium tuberculosis infection in United States Navy recruits using the tuberculin skin test or whole-blood interferon-γ release assays. Clin Infect Dis 2007; 45:826-836.
28. Diel R, Nienhaus A, Lange C, Schaberg T. Cost-optimisation of screening for latent tuberculosis in close contacts. Eur Respir J 2006; 28:35-44.
29. Jensen PA, Lambert LA, Iademarco MF, Ridzon R. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005. MMWR Recomm Rep 2005; 54(RR-17):1-141.