Should specialized oncogeriatric surgeons operate older unfit cancer patients?

European Journal of Surgical Oncology

Volumn 36, Issue SUPPL. 1, 2010, Pages

  Van Leeuwen, B L ^a   Kristjansson, S R ^b   Audisio, R A ^c  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Cancer surgery; Elderly; Frailty; Older patients; Oncogeriatric; Outcomes; Surgical risk

Indexed keywords

CANCER PATIENT; CANCER SURGERY; GERIATRIC CARE; HUMAN; PATIENT DECISION MAKING; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REVIEW; SPECIALIZATION; SURGEON; TREATMENT OUTCOME;

EID: 77955710994     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2010.06.018     Document Type: Article

References (50)

1. R.A. DePinho The age of cancer Nature 408 2000 248 254
2. T.B. Kirkwood A systematic look at an old problem Nature 451 2008 644 647
3. M.L.G. Janssen-Heijnen, S. Houterman, V.E.P.P. Lemmens, M.W. Louwman, H.A. Maas, and J.W. Coebergh Prognostic impact of increasing age and co-morbidity in cancer patients: a population-based approach Crit Rev Oncol Hematol 55 2005 231 240
4. B.H. Endreseth, P. Romundstad, H.E. Myrvold, and A. Wibe Norwegian Rectal Cancer Group. Rectal cancer treatment of the elderly Colorectal Dis 8 2006 471 479
5. M.D. Peake, S. Thompson, D. Lowe, and M.G. Pearson Participating Centres. Ageism in the management of lung cancer Age Ageing 32 2003 171 177
6. PACE participants R.A. Audisio, and D. Pope, et al. Shall we operate? preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study Crit Rev Oncol Hematol 65 2008 156 163
7. F.E. Turrentine, H. Wang, V.B. Simpson, and R.S. Jones Surgical risk factors, morbidity, and mortality in elderly patients J Am Coll Surg 203 2006 865 877
8. M.B. Hamel, W.G. Henderson, S.F. Khuri, and J. Daley Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery J Am Geriatr Soc 53 2005 424 429
9. J.M. Leung, and S. Dzankic Relative importance of preoperative health status versus intraoperative factors in predicting postoperative adverse outcomes in geriatric surgical patients J Am Geriatr Soc 49 2001 1080 1085
10. L.F. Hutchins, J.M. Unger, J.J. Crowley, C.A. Coltman Jr., and K.S. Albain Underrepresentation of patients 65 years of age or older in cancer-treatment trials N Engl J Med 341 1999 2061 2067
11. A. Adunsky, A. Lusky, M. Arad, and R.J. Heruti A comparative study of rehabilitation outcomes of elderly hip fracture patients: the advantage of a comprehensive orthogeriatric approach J Gerontol Ser A Biol Sci Med Sci 58 2003 542 547
12. I. Saltvedt, E.S. Mo, P. Fayers, S. Kaasa, and O. Sletvold Reduced mortality in treating acutely sick, frail older patients in a geriatric evaluation and management unit. A prospective randomized trial J Am Geriatr Soc 50 2002 792 798
13. A. Adunsky, M. Arad, R. Levi, A. Blankstein, G. Zeilig, and E. Mizrachi Five-year experience with the 'Sheba' model of comprehensive orthogeriatric care for elderly hip fracture patients Disabil Rehabil 27 2005 1123 1127
14. L.C. Walter, and K.E. Covinsky Cancer screening in elderly patients: a framework for individualized decision making JAMA 285 2001 2750 2756
15. H.G. Welch, P.C. Albertsen, R.F. Nease, T.A. Bubolz, and J.H. Wasson Estimating treatment benefits for the elderly: the effect of competing risks Ann Intern Med 124 1996 577 584
16. M.B. Hamel, J. Lynn, and J.M. Teno, et al. Age-related differences in care preferences, treatment decisions, and clinical outcomes of seriously ill hospitalized adults: lessons from SUPPORT J Am Geriatr Soc 48 2000 S176 S182
17. A. Ajaj, M.P. Singh, and A.J. Abdulla Should elderly patients be told they have cancer? questionnaire survey of older people BMJ 323 2001 1160
18. Kristjansson SR, Nesbakken A, Jordhoy MS, Skovlund E, Audisio RA, Johannessen HO, Bakka A, Wyller TB. Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: a prospective observational cohort study. Crit Rev Oncol Hematol, submitted for publication.
19. O. Sjo, S. Larsen, O. Lunde, and A. Nesbakken Short term outcome after emergency and elective surgery for colon cancer Colorectal Dis 11 2009 733 739
20. D. Pope, H. Ramesh, and R. Gennari, et al. Pre-operative assessment of cancer in the elderly (PACE): a comprehensive assessment of underlying characteristics of elderly cancer patients prior to elective surgery Surg Oncol 15 2006 189 197
21. F.C. Martin, and P. Brighton Frailty: different tools for different purposes? Age Ageing 37 2008 129 131
22. S.K. Inouye, S.T. Bogardus, and P.A. Charpentier, et al. A multicomponent intervention to prevent delirium in hospitalized older patients N Engl J Med 340 1999 669 676
23. W.B. Al Refaie, H.M. Parsons, and W.G. Henderson, et al. Major cancer surgery in the elderly: results from the American College of Surgeons National Surgical Quality Improvement Program Ann Surg 251 2010 311 318
24. N.N. Massarweh, V.J. Legner, R.G. Symons, W.C. McCormick, and D.R. Flum Impact of advancing age on abdominal surgical outcomes Arch Surg 144 2009 1108 1114
25. G.J. Gardner Ovarian cancer cytoreductive surgery in the elderly Curr Treat Options Oncol 10 2009 171 179
26. M.F. Berry, J. Hanna, and B.C. Tong, et al. Risk factors for morbidity after lobectomy for lung cancer in elderly patients Ann Thorac Surg 88 2009 1093 1099
27. V.A. Lawrence, H.P. Hazuda, and J.E. Cornell, et al. Functional independence after major abdominal surgery in the elderly J Am Coll Surg 199 2004 762 772
28. D.J. Culley, Z. Xie, and G. Crosby General anesthetic-induced neurotoxicity: an emerging problem for the young and old? Curr Opin Anaesthesiol 20 2007 408 413
29. L.S. Rasmussen Postoperative cognitive dysfunction: incidence and prevention Best Pract Res Clin Anaesthesiol 20 2006 315 330
30. N. Stroobant, G. Van Nooten, D. DeBacquer, Y. Van Belleghem, and G. Vingerhoets Neuropsychological functioning 3-5 years after coronary artery bypass grafting: does the pump make a difference? Eur J Cardio Thor Surg 396-401 2008
31. T.N. van den Kommer, M.G. Dik, H.C. Comijs, C. Jonker, and D.J.H. Deeg Homocysteine and inflammation: predictors of cognitive decline in older persons? Neurobiol Aging 2008 10.1016/jneurobiolaging.2008.09.009
32. E. Exel, A.J.M. Craen, E.J. Remarque, and J. Gussekloo, et al. Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function Neurology 61 2003 1695 1701
33. Hu Z, Ou Y, Duan K, Jiang X. Inflammation: a bridge between postoperative cognitive dysfunction and Alzheimer's disease. Med Hypotheses. doi:10.1016/jmehy.2009.10.040.
34. L. Ansaloni, F. Catena, and R. Chattat, et al. Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgery Br J Surg 97 2010 273 280
35. A.G. Benoit, B.I. Campbell, and J.R. Tanner, et al. Risk factors and prevalence of perioperative cognitive dysfunction in abdominal aneurysm patients J Vasc Surg 42 2005 884 890
36. E.R. Marcantonio, L. Goldman, E.J. Orav, E.F. Cook, and T.H. Lee The association of intraoperative factors with the development of postoperative delirium Am J Med 105 1998 380 384
37. J. Francis, D. Martin, and W.N. Kapoor A prospective study of delirium in hospitalized elderly JAMA 263 1990 1097 1101
38. M.M. Beliveau, and M. Multach Perioperative care for the elderly patient Med Clin North Am 87 2003 273 289
39. H.J. Rutten, M. den Dulk, V.E. Lemmens, C.J. van de Velde, and C.A. Marijnen Controversies of total mesorectal excision for rectal cancer in elderly patients Lancet Oncol 9 2008 494 501
40. V.J. Legner, N.N. Massarweh, R.G. Symons, W.C. McCormick, and D.R. Flum The significance of discharge to skilled care after abdominopelvic surgery in older adults Ann Surg 249 2009 250 255
41. C. Owusu, T.L. Lash, and R.A. Silliman Effect of undertreatment on the disparity in age-related breast cancer-specific survival among older women Breast Cancer Res Treat 102 2007 227 236
42. C. Bouchardy, E. Rapiti, and G. Fioretta, et al. Undertreatment strongly decreases prognosis of breast cancer in elderly women Clin Oncol 21 2003 3580 3587
43. A. Habr-Gama, and R.O. Perez Non-operative management of rectal cancer after neoadjuvant chemoradiation Br J Surg 96 2009 125 127
44. A. Volpe The role of surveillance in the management of small renal masses ScientificWorldJournal 7 2007 860 868
45. G. Baatrup, B. Breum, and N. Qvist, et al. Transanal endoscopic microsurgery in 143 consecutive patients with rectal adenocarcinoma: results from a Danish multicenter study Colorectal Dis 11 2009 270 275
46. M. Tei, M. Ikeda, and N. Haraguchi, et al. Postoperative complications in elderly patients with colorectal cancer: comparison of open and laparoscopic surgical procedures Surg Laparosc Endosc Percutan Tech 19 2009 488 492
47. J.P. Wisnivesky, C.L. Henschke, and S. Swanson, et al. Limited resection for the treatment of patients with stage IA lung cancer Ann Surg 251 2010 550 554
48. S. Sebastian, S. Johnston, T. Geoghegan, W. Torreggiani, and M. Buckley Pooled analysis of the efficacy and safety of self expanding metal stenting in malignant colorectal obstruction Am J Gastroenterol 99 2004 2051 2057
49. T.P. Webb, and E. Duthie Jr. Geriatrics for surgeons: infusing life into an aging subject J Surg Educ 65 2008 91 94
50. Cicerchia M, Ceci M, Locatelli C, Gianni W, and Repetto L. Geriatric syndromes in peri-operative elderly cancer patients. Surg Oncol, submitted for publication.