Determining the molecular interactions of perfluorinated carboxylic acids with human sera and isolated human serum albumin using nuclear magnetic resonance spectroscopy

Environmental Toxicology and Chemistry

Volumn 29, Issue 8, 2010, Pages 1678-1688

  D'Eon, Jessica C ^a   Simpson, André J ^a   Kumar, Rajeev ^a   Baer, Andrew J ^a   Mabury, Scott A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Perfluorinated carboxylic acid; Perfluorohexanoic acid; Perfluorooctaonic acid; Serum albumin; Sudlow's drug binding sites

Indexed keywords

DRUG BINDING; PERFLUORINATED CARBOXYLIC ACIDS; PERFLUOROHEXANOIC ACID; PERFLUOROOCTAONIC ACID; SERUM ALBUMIN;

ACTIVE NETWORKS; BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; BODY FLUIDS; CARBOXYLIC ACIDS; DRUG PRODUCTS; EXPERIMENTS; LIGANDS; MAGNETIC RESONANCE SPECTROMETERS; MOLECULAR INTERACTIONS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLEIC ACID; ORGANIC ACIDS; PARTICLE DETECTORS; QUANTUM THEORY; RESONANCE;

DRUG INTERACTIONS;

IBUPROFEN; OLEIC ACID; PERFLUOROHEXANOIC ACID; PERFLUOROOCTANOIC ACID; PHENYLBUTAZONE; SERUM ALBUMIN; UNCLASSIFIED DRUG;

BIOACCUMULATION; CARBOXYLIC ACID; DRUG; EXPERIMENTAL STUDY; MOLECULAR ANALYSIS; NUCLEAR MAGNETIC RESONANCE; PROTEIN; SERUM; SPECTROSCOPY;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOACCUMULATION; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG PROTEIN BINDING; FLUORINE NUCLEAR MAGNETIC RESONANCE; HETERONUCLEAR SATURATION TRANSFER DIFFERENCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; MALE; MOLECULAR INTERACTION; ORGANIC POLLUTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SERUM; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CARBOXYLIC ACIDS; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; HEXANOIC ACIDS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; OCTANOIC ACIDS; SERUM ALBUMIN;

EID: 77955686472     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.204     Document Type: Article

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