메뉴 건너뛰기




Volumn 40, Issue 4, 2010, Pages 253-262

Lactosaminated human albumin, a hepatotropic carrier of drugs

Author keywords

Hepatocellular carcinoma; Liver micrometastases; Liver targeting of drugs; Viral hepatitis

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; DOXORUBICIN; DRUG CARRIER; FLOXURIDINE; FLUOROURACIL; LACTOSAMINATED HUMAN ALBUMIN; UNCLASSIFIED DRUG; VIDARABINE; VIDARABINE PHOSPHATE; ALB PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; GLYCOPROTEIN; LACTOSAMINATED SERUM ALBUMIN; SERUM ALBUMIN;

EID: 77955684788     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.04.004     Document Type: Review
Times cited : (34)

References (86)
  • 1
    • 0025811492 scopus 로고
    • Hepatobiliary toxicity of 5-fluoro-2'-deoxyuridine. Intra-arterial versus portal venous routes of infusion
    • Andrews J.C., Kunsten C., Terio P., Priescorn D., Ensminger W. Hepatobiliary toxicity of 5-fluoro-2'-deoxyuridine. Intra-arterial versus portal venous routes of infusion. Invest. Radiol. 1991, 26:461-464.
    • (1991) Invest. Radiol. , vol.26 , pp. 461-464
    • Andrews, J.C.1    Kunsten, C.2    Terio, P.3    Priescorn, D.4    Ensminger, W.5
  • 2
    • 0016322758 scopus 로고
    • The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins
    • Ashwell G., Morell A.G. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv. Enzymol. 1974, 41:99-128.
    • (1974) Adv. Enzymol. , vol.41 , pp. 99-128
    • Ashwell, G.1    Morell, A.G.2
  • 3
    • 33645471018 scopus 로고
    • Phosphorylation through glyoxalines [imidazolides] and its significance in enzymic transphosphorylation
    • Baddiley J., Buchanan J.G., Letters R. Phosphorylation through glyoxalines [imidazolides] and its significance in enzymic transphosphorylation. J. Chem. Soc. 1956, 2812-2817.
    • (1956) J. Chem. Soc. , pp. 2812-2817
    • Baddiley, J.1    Buchanan, J.G.2    Letters, R.3
  • 4
    • 54249138300 scopus 로고    scopus 로고
    • Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties
    • Baglioni M., Fiume L., Bolondi L., Farina C., Kratz F., Di Stefano G. Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties. Dig. Liver Dis. 2008, 40:963-964.
    • (2008) Dig. Liver Dis. , vol.40 , pp. 963-964
    • Baglioni, M.1    Fiume, L.2    Bolondi, L.3    Farina, C.4    Kratz, F.5    Di Stefano, G.6
  • 5
    • 0027967602 scopus 로고
    • Synthesis of dioleoyl derivative of iododeoxyuridine and its incorporation into reconstituted high density lipoprotein particles
    • Bijsterbosch M.K., Schouten D., van Berkel T.J.C. Synthesis of dioleoyl derivative of iododeoxyuridine and its incorporation into reconstituted high density lipoprotein particles. Biochemistry 1994, 33:14073-14080.
    • (1994) Biochemistry , vol.33 , pp. 14073-14080
    • Bijsterbosch, M.K.1    Schouten, D.2    van Berkel, T.J.C.3
  • 7
    • 4043071644 scopus 로고
    • The cyanohydroborate anion as a selective reducing agent
    • Borch R.F., Bernstein M.D., Durst H.D. The cyanohydroborate anion as a selective reducing agent. J. Am. Chem. Soc. 1971, 93:2897-2904.
    • (1971) J. Am. Chem. Soc. , vol.93 , pp. 2897-2904
    • Borch, R.F.1    Bernstein, M.D.2    Durst, H.D.3
  • 8
    • 0018096163 scopus 로고
    • HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine
    • Chadwick R.G., Bassendine M.F., Crawford E.M., Thomas H.C., Sherlock S. HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine. Br. Med. J. 1978, 2:531-533.
    • (1978) Br. Med. J. , vol.2 , pp. 531-533
    • Chadwick, R.G.1    Bassendine, M.F.2    Crawford, E.M.3    Thomas, H.C.4    Sherlock, S.5
  • 9
    • 0020539326 scopus 로고
    • The peribiliary vascular plexus: the microvascular architecture of the bile duct in the rabbit and in clinical cases
    • Cho K.J., Lunderquist A. The peribiliary vascular plexus: the microvascular architecture of the bile duct in the rabbit and in clinical cases. Radiology 1983, 147:357-364.
    • (1983) Radiology , vol.147 , pp. 357-364
    • Cho, K.J.1    Lunderquist, A.2
  • 10
    • 33847167237 scopus 로고
    • Mechanism and catalysis of reactions of acyl phosphates. I. Nucleophilic reactions
    • Di Sabato G., Jencks W.P. Mechanism and catalysis of reactions of acyl phosphates. I. Nucleophilic reactions. J. Am. Chem. Soc. 1961, 83:4393-4400.
    • (1961) J. Am. Chem. Soc. , vol.83 , pp. 4393-4400
    • Di Sabato, G.1    Jencks, W.P.2
  • 11
    • 0036083670 scopus 로고    scopus 로고
    • Floxuridine coupling with lactosaminated human albumin to increase the drug efficacy on liver micrometastases
    • Di Stefano G., Busi C., Fiume L. Floxuridine coupling with lactosaminated human albumin to increase the drug efficacy on liver micrometastases. Dig. Liver Dis. 2002, 34:439-446.
    • (2002) Dig. Liver Dis. , vol.34 , pp. 439-446
    • Di Stefano, G.1    Busi, C.2    Fiume, L.3
  • 12
    • 77955685690 scopus 로고    scopus 로고
    • Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-l-lysine coupling: implications for regional chemotherapy of hepatic micrometastases
    • Di Stefano G., Busi C., Camerino A., Nardo B., Fiume L. Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-l-lysine coupling: implications for regional chemotherapy of hepatic micrometastases. Biochem. Pharmacol. 2000, 61:457-463.
    • (2000) Biochem. Pharmacol. , vol.61 , pp. 457-463
    • Di Stefano, G.1    Busi, C.2    Camerino, A.3    Nardo, B.4    Fiume, L.5
  • 13
    • 0032587308 scopus 로고    scopus 로고
    • 3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-l-lysine
    • 3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-l-lysine. Biochem. Pharmacol. 1999, 57:793-799.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 793-799
    • Di Stefano, G.1    Busi, C.2    Mattioli, A.3    Derenzini, M.4    Trerè, D.5    Fiume, L.6
  • 14
    • 0029008855 scopus 로고
    • Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-l-lysine and administered to mice by intramuscular route
    • Di Stefano G., Busi C., Mattioli A., Fiume L. Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-l-lysine and administered to mice by intramuscular route. Biochem. Pharmacol. 1995, 49:1769-1775.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 1769-1775
    • Di Stefano, G.1    Busi, C.2    Mattioli, A.3    Fiume, L.4
  • 15
    • 0030868838 scopus 로고    scopus 로고
    • Ribavirin conjugated with lactosaminated poly-l-lysine. Selective delivery to the liver and increased antiviral activity in mice with viral hepatitis
    • Di Stefano G., Colonna F.P., Bongini A., Busi C., Mattioli A., Fiume L. Ribavirin conjugated with lactosaminated poly-l-lysine. Selective delivery to the liver and increased antiviral activity in mice with viral hepatitis. Biochem. Pharmacol. 1997, 54:357-363.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 357-363
    • Di Stefano, G.1    Colonna, F.P.2    Bongini, A.3    Busi, C.4    Mattioli, A.5    Fiume, L.6
  • 16
    • 3142705894 scopus 로고    scopus 로고
    • Liver targeted doxorubicin: effects on regenerating rat hepatocytes
    • Di Stefano G., Derenzini M., Kratz F., Lanza M., Fiume L. Liver targeted doxorubicin: effects on regenerating rat hepatocytes. Liver Int. 2004, 24:246-252.
    • (2004) Liver Int. , vol.24 , pp. 246-252
    • Di Stefano, G.1    Derenzini, M.2    Kratz, F.3    Lanza, M.4    Fiume, L.5
  • 17
    • 33745589227 scopus 로고    scopus 로고
    • A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade
    • Di Stefano G., Fiume L., Baglioni M., Bolondi L., Busi C., Chieco P., Kratz F., Manaresi F., Pariali M. A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade. Liver Int. 2006, 26:726-733.
    • (2006) Liver Int. , vol.26 , pp. 726-733
    • Di Stefano, G.1    Fiume, L.2    Baglioni, M.3    Bolondi, L.4    Busi, C.5    Chieco, P.6    Kratz, F.7    Manaresi, F.8    Pariali, M.9
  • 20
    • 33846457561 scopus 로고    scopus 로고
    • Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin
    • Di Stefano G., Fiume L., Baglioni M., Busi C., Chieco P., Kratz F., Mattioli A. Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin. Eur. J. Pharm. Sci. 2007, 30:136-142.
    • (2007) Eur. J. Pharm. Sci. , vol.30 , pp. 136-142
    • Di Stefano, G.1    Fiume, L.2    Baglioni, M.3    Busi, C.4    Chieco, P.5    Kratz, F.6    Mattioli, A.7
  • 21
    • 22844437949 scopus 로고    scopus 로고
    • Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors
    • Di Stefano G., Fiume L., Bolondi L., Lanza M., Pariali M., Chieco P. Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors. Liver Int. 2005, 25:854-860.
    • (2005) Liver Int. , vol.25 , pp. 854-860
    • Di Stefano, G.1    Fiume, L.2    Bolondi, L.3    Lanza, M.4    Pariali, M.5    Chieco, P.6
  • 23
    • 0142093581 scopus 로고    scopus 로고
    • Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier
    • Di Stefano G., Kratz F., Lanza M., Fiume L. Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier. Dig. Liver Dis. 2003, 35:428-433.
    • (2003) Dig. Liver Dis. , vol.35 , pp. 428-433
    • Di Stefano, G.1    Kratz, F.2    Lanza, M.3    Fiume, L.4
  • 24
    • 0036228266 scopus 로고    scopus 로고
    • Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy
    • Di Stefano G., Lanza M., Busi C., Barbieri L., Fiume L. Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy. J. Pharm. Exp. Ther. 2002, 301:638-642.
    • (2002) J. Pharm. Exp. Ther. , vol.301 , pp. 638-642
    • Di Stefano, G.1    Lanza, M.2    Busi, C.3    Barbieri, L.4    Fiume, L.5
  • 25
    • 9644258956 scopus 로고    scopus 로고
    • A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate
    • Di Stefano G., Lanza M., Kratz F., Merina L., Fiume L. A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate. Eur. J. Pharm. Sci. 2004, 23:393-397.
    • (2004) Eur. J. Pharm. Sci. , vol.23 , pp. 393-397
    • Di Stefano, G.1    Lanza, M.2    Kratz, F.3    Merina, L.4    Fiume, L.5
  • 26
    • 0242443366 scopus 로고    scopus 로고
    • Synthesis and physicochemical characterisitcs of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin
    • Di Stefano G., Tubaro M., Lanza M., Boga C., Fiume L., Traldi P. Synthesis and physicochemical characterisitcs of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin. Rapid Commun. Mass Spectrom. 2003, 17:2503-2507.
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 2503-2507
    • Di Stefano, G.1    Tubaro, M.2    Lanza, M.3    Boga, C.4    Fiume, L.5    Traldi, P.6
  • 27
    • 0020529031 scopus 로고
    • Regional chemotherapy of neoplastic diseases
    • Ensminger W.D., Gyves J.W. Regional chemotherapy of neoplastic diseases. Pharmacol. Ther. 1983, 21:277-293.
    • (1983) Pharmacol. Ther. , vol.21 , pp. 277-293
    • Ensminger, W.D.1    Gyves, J.W.2
  • 28
    • 0018166964 scopus 로고
    • A clinical-pharmacological evaluation of hepatic arterial infusion of 5-fluoro 2'-deoxyuridine and 5-fluorouracil
    • Ensminger W.D., Rosowsky A., Raso V., Levin D.C., Glode M., Come S., Steele G., Frei E. A clinical-pharmacological evaluation of hepatic arterial infusion of 5-fluoro 2'-deoxyuridine and 5-fluorouracil. Cancer Res. 1978, 38:3784-3792.
    • (1978) Cancer Res. , vol.38 , pp. 3784-3792
    • Ensminger, W.D.1    Rosowsky, A.2    Raso, V.3    Levin, D.C.4    Glode, M.5    Come, S.6    Steele, G.7    Frei, E.8
  • 29
    • 0026793996 scopus 로고
    • Randomised controlled trial of adjuvant chemotherapy by portal-vein perfusion after curative resection for colorectal adenocarcinoma
    • Fielding L.P., Hittinger R., Grace R.H., Fry J.S. Randomised controlled trial of adjuvant chemotherapy by portal-vein perfusion after curative resection for colorectal adenocarcinoma. Lancet 1992, 340:502-506.
    • (1992) Lancet , vol.340 , pp. 502-506
    • Fielding, L.P.1    Hittinger, R.2    Grace, R.H.3    Fry, J.S.4
  • 30
    • 0014683523 scopus 로고
    • Penetration of β-amanitin-rabbit-albumin conjugate into hepatic parenchymal cells
    • Fiume L. Penetration of β-amanitin-rabbit-albumin conjugate into hepatic parenchymal cells. Lancet 1969, 2:853-854.
    • (1969) Lancet , vol.2 , pp. 853-854
    • Fiume, L.1
  • 31
    • 0023896297 scopus 로고
    • Conjugates of 9-β-d-arabinofuranosyladenine 5'-monophosphate (ara-AMP) with lactosaminated albumin: characterization of the drug-carrier bonds
    • Fiume L., Bassi B., Bongini A. Conjugates of 9-β-d-arabinofuranosyladenine 5'-monophosphate (ara-AMP) with lactosaminated albumin: characterization of the drug-carrier bonds. Pharm. Acta Helv. 1988, 63:137-139.
    • (1988) Pharm. Acta Helv. , vol.63 , pp. 137-139
    • Fiume, L.1    Bassi, B.2    Bongini, A.3
  • 32
    • 0022357014 scopus 로고
    • Preparation of lactosaminated albumin-ara-AMP conjugate which remains soluble after lyophilization
    • Fiume L., Bassi B., Busi C., Mattioli A. Preparation of lactosaminated albumin-ara-AMP conjugate which remains soluble after lyophilization. Pharm. Acta Helv. 1985, 60:318-320.
    • (1985) Pharm. Acta Helv. , vol.60 , pp. 318-320
    • Fiume, L.1    Bassi, B.2    Busi, C.3    Mattioli, A.4
  • 33
    • 0022516737 scopus 로고
    • Drug targeting in antiviral chemotherapy. A chemically stable conjugate of 9-β-d-arabinofuranosyladenine 5'-monophosphate with lactosaminated albumin accomplishes a selective delivery of the drug to liver cells
    • Fiume L., Bassi B., Busi C., Mattioli A., Spinosa G. Drug targeting in antiviral chemotherapy. A chemically stable conjugate of 9-β-d-arabinofuranosyladenine 5'-monophosphate with lactosaminated albumin accomplishes a selective delivery of the drug to liver cells. Biochem. Pharmacol. 1986, 35:967-972.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 967-972
    • Fiume, L.1    Bassi, B.2    Busi, C.3    Mattioli, A.4    Spinosa, G.5
  • 34
    • 0026784838 scopus 로고
    • The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin
    • Fiume L., Betts C.M., Busi C., Corzani S., Derenzini M., Di Stefano G., Mattioli A. The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin. J. Hepatol. 1992, 15:314-322.
    • (1992) J. Hepatol. , vol.15 , pp. 314-322
    • Fiume, L.1    Betts, C.M.2    Busi, C.3    Corzani, S.4    Derenzini, M.5    Di Stefano, G.6    Mattioli, A.7
  • 35
    • 24344508224 scopus 로고    scopus 로고
    • Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine
    • Fiume L., Bolondi L., Busi C., Chieco P., Kratz F., Lanza M., Mattioli A., Di Stefano G. Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine. J. Hepatol. 2005, 43:645-652.
    • (2005) J. Hepatol. , vol.43 , pp. 645-652
    • Fiume, L.1    Bolondi, L.2    Busi, C.3    Chieco, P.4    Kratz, F.5    Lanza, M.6    Mattioli, A.7    Di Stefano, G.8
  • 36
    • 0028278870 scopus 로고
    • Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosamianted albumin in the rat
    • Fiume L., Busi C., Corzani S., Di Stefano G., Gervasi G.B., Mattioli A. Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosamianted albumin in the rat. J. Hepatol. 1994, 20:681-682.
    • (1994) J. Hepatol. , vol.20 , pp. 681-682
    • Fiume, L.1    Busi, C.2    Corzani, S.3    Di Stefano, G.4    Gervasi, G.B.5    Mattioli, A.6
  • 37
    • 0027181469 scopus 로고
    • Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters
    • Fiume L., Busi C., Di Stefano G., Mattioli A. Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters. Anal. Biochem. 1993, 212:407-411.
    • (1993) Anal. Biochem. , vol.212 , pp. 407-411
    • Fiume, L.1    Busi, C.2    Di Stefano, G.3    Mattioli, A.4
  • 38
    • 0020363756 scopus 로고
    • Lactosaminated human serum albumin as hepatotropic drug carrier. Rate of uptake by mouse liver
    • Fiume L., Busi C., Mattioli A. Lactosaminated human serum albumin as hepatotropic drug carrier. Rate of uptake by mouse liver. FEBS Lett. 1982, 146:42-46.
    • (1982) FEBS Lett. , vol.146 , pp. 42-46
    • Fiume, L.1    Busi, C.2    Mattioli, A.3
  • 39
    • 0019440950 scopus 로고
    • Hepatocyte targeting of adenine-9-β-d-arabinofuranoside 5'-monophosphate (ara-AMP) coupled to lactosaminated albumin
    • Fiume L., Busi C., Mattioli A., Balboni P.G., Barbanti-Brodano G. Hepatocyte targeting of adenine-9-β-d-arabinofuranoside 5'-monophosphate (ara-AMP) coupled to lactosaminated albumin. FEBS Lett. 1981, 129:261-264.
    • (1981) FEBS Lett. , vol.129 , pp. 261-264
    • Fiume, L.1    Busi, C.2    Mattioli, A.3    Balboni, P.G.4    Barbanti-Brodano, G.5
  • 40
    • 0023550778 scopus 로고
    • Conjugates of ara-AMP with lactosaminated albumin: a study on their immunogenicity in mouse and rat
    • Fiume L., Busi C., Preti P., Spinosa G. Conjugates of ara-AMP with lactosaminated albumin: a study on their immunogenicity in mouse and rat. Cancer Drug Deliv. 1987, 4:145-150.
    • (1987) Cancer Drug Deliv. , vol.4 , pp. 145-150
    • Fiume, L.1    Busi, C.2    Preti, P.3    Spinosa, G.4
  • 41
    • 0015222792 scopus 로고
    • Facilitated penetration of amanitin-albumin conjugates into hepatocytes after coupling with fluorescein
    • Fiume L., Campadelli Fiume G., Wieland T. Facilitated penetration of amanitin-albumin conjugates into hepatocytes after coupling with fluorescein. Nat. New Biol. 1971, 230:219-220.
    • (1971) Nat. New Biol. , vol.230 , pp. 219-220
    • Fiume, L.1    Campadelli Fiume, G.2    Wieland, T.3
  • 43
    • 0019211060 scopus 로고
    • Selective inhibition of Ectromelia virus DNA synthesis in hepatocytes by adenine-9-β-d-arabinofuranoside (ara-A) and adenine-9-β-d-arabinofuranoside 5'-monophosphate (ara-AMP) conjugated to asialofetuin
    • Fiume L., Mattioli A., Busi C., Balboni P.G., Barbanti-Brodano G., De Vries J., Altman L., Wieland T. Selective inhibition of Ectromelia virus DNA synthesis in hepatocytes by adenine-9-β-d-arabinofuranoside (ara-A) and adenine-9-β-d-arabinofuranoside 5'-monophosphate (ara-AMP) conjugated to asialofetuin. FEBS Lett. 1980, 116:185-188.
    • (1980) FEBS Lett. , vol.116 , pp. 185-188
    • Fiume, L.1    Mattioli, A.2    Busi, C.3    Balboni, P.G.4    Barbanti-Brodano, G.5    De Vries, J.6    Altman, L.7    Wieland, T.8
  • 44
    • 0020359596 scopus 로고
    • Conjugtes of adenine-9-β-d-arabinofuranoside monophosphate (ara-AMP) with lactosaminated homologous albumin are not immunogenic in the mouse
    • Fiume L., Mattioli A., Busi C., Spinosa G., Wieland T. Conjugtes of adenine-9-β-d-arabinofuranoside monophosphate (ara-AMP) with lactosaminated homologous albumin are not immunogenic in the mouse. Experientia 1982, 38:1087-1089.
    • (1982) Experientia , vol.38 , pp. 1087-1089
    • Fiume, L.1    Mattioli, A.2    Busi, C.3    Spinosa, G.4    Wieland, T.5
  • 46
  • 47
    • 0016224101 scopus 로고
    • The direct coupling of oligosaccharides to proteins and derivatized gels
    • Gray G.R. The direct coupling of oligosaccharides to proteins and derivatized gels. Arch. Biochem. Biophys. 1974, 163:426-428.
    • (1974) Arch. Biochem. Biophys. , vol.163 , pp. 426-428
    • Gray, G.R.1
  • 50
    • 0013890353 scopus 로고
    • The preparation of nucleotide protein conjugates: carbodiimides as coupling agents
    • Halloran M.J., Parker C.W. The preparation of nucleotide protein conjugates: carbodiimides as coupling agents. J. Immunol. 1966, 96:373-378.
    • (1966) J. Immunol. , vol.96 , pp. 373-378
    • Halloran, M.J.1    Parker, C.W.2
  • 51
    • 0023270608 scopus 로고
    • Patterns of ligand binding to normal, regenerating, preneoplastic, and neoplastic rat hepatocytes
    • Harris L., Preat V., Farber E. Patterns of ligand binding to normal, regenerating, preneoplastic, and neoplastic rat hepatocytes. Cancer Res. 1987, 47:3954-3958.
    • (1987) Cancer Res. , vol.47 , pp. 3954-3958
    • Harris, L.1    Preat, V.2    Farber, E.3
  • 52
    • 0014216749 scopus 로고
    • A method for the quantitative modification and estimationof carboxylic acid groups in proteins
    • Hoare D.G., Koshland D.E. A method for the quantitative modification and estimationof carboxylic acid groups in proteins. J. Biol. Chem. 1967, 242:2447-2453.
    • (1967) J. Biol. Chem. , vol.242 , pp. 2447-2453
    • Hoare, D.G.1    Koshland, D.E.2
  • 55
    • 0026570019 scopus 로고
    • A randomized trial of intrahepatic infusion of fluorodeoxyuridine with dexamethasone versus fluorodeoxyuridine alone in the treatment of metastatic colorectal cancer
    • Kemeny N., Seiter K., Niedzwiecki D., Chapman D., Sigurdson E., Cohen A., Botet J., Oderman P., Murray P. A randomized trial of intrahepatic infusion of fluorodeoxyuridine with dexamethasone versus fluorodeoxyuridine alone in the treatment of metastatic colorectal cancer. Cancer 1992, 69:327-334.
    • (1992) Cancer , vol.69 , pp. 327-334
    • Kemeny, N.1    Seiter, K.2    Niedzwiecki, D.3    Chapman, D.4    Sigurdson, E.5    Cohen, A.6    Botet, J.7    Oderman, P.8    Murray, P.9
  • 56
    • 75749149269 scopus 로고    scopus 로고
    • HPMA copolymers: origins, early developments, present, and future
    • Kopecek J., Kopeckova P. HPMA copolymers: origins, early developments, present, and future. Adv. Drug Deliv. Rev. 2010, 62:122-149.
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 122-149
    • Kopecek, J.1    Kopeckova, P.2
  • 57
    • 0017092940 scopus 로고
    • Attachment of thioglycoside to proteins: enhancement of liver membrane binding
    • Krantz M.J., Holtzman N.A., Stowell C.P., Lee Y.C. Attachment of thioglycoside to proteins: enhancement of liver membrane binding. Biochemistry 1976, 15:3963-3968.
    • (1976) Biochemistry , vol.15 , pp. 3963-3968
    • Krantz, M.J.1    Holtzman, N.A.2    Stowell, C.P.3    Lee, Y.C.4
  • 58
  • 59
    • 0001512390 scopus 로고
    • Preferential formation of (2'-5')-linked internucleotide bonds in non-enzymatic reactions
    • Lohrmann R., Orgel R.E. Preferential formation of (2'-5')-linked internucleotide bonds in non-enzymatic reactions. Tetrahedron 1978, 34:853-855.
    • (1978) Tetrahedron , vol.34 , pp. 853-855
    • Lohrmann, R.1    Orgel, R.E.2
  • 61
    • 0013923653 scopus 로고
    • The terminal distribution of hepatic artery with special reference to arterio-portal anastomosis
    • Mitra S.K. The terminal distribution of hepatic artery with special reference to arterio-portal anastomosis. J. Anat. 1966, 100:651-663.
    • (1966) J. Anat. , vol.100 , pp. 651-663
    • Mitra, S.K.1
  • 62
    • 0024309206 scopus 로고
    • Effect of galactose on interaction of N-(2-hydroxypropyl) metacrylamide copolymers with hepatoma cells in culture: preliminary applications to an anticancer agents, daunomycin
    • O'Hare K.B., Hume I.C., Scarlett L., Chytry V., Kopeckova P., Kopecek J., Duncan R. Effect of galactose on interaction of N-(2-hydroxypropyl) metacrylamide copolymers with hepatoma cells in culture: preliminary applications to an anticancer agents, daunomycin. Hepatology 1989, 10:207-214.
    • (1989) Hepatology , vol.10 , pp. 207-214
    • O'Hare, K.B.1    Hume, I.C.2    Scarlett, L.3    Chytry, V.4    Kopeckova, P.5    Kopecek, J.6    Duncan, R.7
  • 64
    • 0021257853 scopus 로고
    • Detection of hepatitis B virus in mononuclear blood cells
    • Pontisso P., Poon M.C., Tiollais P., Brechot C. Detection of hepatitis B virus in mononuclear blood cells. Br. Med J. 1984, 288:1563-1566.
    • (1984) Br. Med J. , vol.288 , pp. 1563-1566
    • Pontisso, P.1    Poon, M.C.2    Tiollais, P.3    Brechot, C.4
  • 66
    • 0015896015 scopus 로고
    • The microcirculatory hepatic unit
    • Rappaport A.M. The microcirculatory hepatic unit. Microvasc. Res. 1973, 6:212-228.
    • (1973) Microvasc. Res. , vol.6 , pp. 212-228
    • Rappaport, A.M.1
  • 67
    • 0015212069 scopus 로고
    • Hepatic uptake of proteins coupled to fetuin glycopeptide
    • Rogers J.C., Kornfeld S. Hepatic uptake of proteins coupled to fetuin glycopeptide. Biochem. Biophys. Res. Commun. 1971, 45:622-629.
    • (1971) Biochem. Biophys. Res. Commun. , vol.45 , pp. 622-629
    • Rogers, J.C.1    Kornfeld, S.2
  • 71
    • 0017397591 scopus 로고
    • Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization
    • Schwartz B.A., Gray G.R. Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization. Arch. Biochem. Biophys. 1977, 181:542-549.
    • (1977) Arch. Biochem. Biophys. , vol.181 , pp. 542-549
    • Schwartz, B.A.1    Gray, G.R.2
  • 73
    • 0013600902 scopus 로고
    • The cross-linking of gelatin using a water-soluble carbodiimide
    • Sheehan J.C., Hlavka J.J. The cross-linking of gelatin using a water-soluble carbodiimide. J. Am. Chem. Soc. 1957, 79:4528-4529.
    • (1957) J. Am. Chem. Soc. , vol.79 , pp. 4528-4529
    • Sheehan, J.C.1    Hlavka, J.J.2
  • 75
    • 0021848221 scopus 로고
    • A randomised controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer
    • Taylor I., Machin D., Mullee M., Trotter G., Cooke T., West C. A randomised controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer. Br. J. Surg. 1985, 72:359-363.
    • (1985) Br. J. Surg. , vol.72 , pp. 359-363
    • Taylor, I.1    Machin, D.2    Mullee, M.3    Trotter, G.4    Cooke, T.5    West, C.6
  • 77
    • 0028353592 scopus 로고
    • Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosamianted albumin. Efficacy and minimal active dose
    • Torrani Cerenzia M.R., Fiume L., Busi C., Mattioli A., Di Stefano G., Gervasi G.B., Brunetto M.R., Piantino P., Verme G. Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosamianted albumin. Efficacy and minimal active dose. J. Hepatol. 1994, 20:307-309.
    • (1994) J. Hepatol. , vol.20 , pp. 307-309
    • Torrani Cerenzia, M.R.1    Fiume, L.2    Busi, C.3    Mattioli, A.4    Di Stefano, G.5    Gervasi, G.B.6    Brunetto, M.R.7    Piantino, P.8    Verme, G.9
  • 78
    • 0032836395 scopus 로고    scopus 로고
    • The asialoglycoprotein receptor in human hepatocellular carcinomas. Its expression on the proliferating cells
    • Trerè D., Fiume L., Badiali De Giorgi L., Di Stefano G., Migaldi M., Derenzini M. The asialoglycoprotein receptor in human hepatocellular carcinomas. Its expression on the proliferating cells. Br. J. Cancer 1999, 81:404-408.
    • (1999) Br. J. Cancer , vol.81 , pp. 404-408
    • Trerè, D.1    Fiume, L.2    Badiali De Giorgi, L.3    Di Stefano, G.4    Migaldi, M.5    Derenzini, M.6
  • 79
    • 0032006318 scopus 로고    scopus 로고
    • Comparison of 5-fluoro-2'-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer
    • van Laar J.A.M., Rustum Y.M., Ackland S.P., van Groeningen C.J., Peters G.J. Comparison of 5-fluoro-2'-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer. Eur. J. Cancer 1998, 34:296-306.
    • (1998) Eur. J. Cancer , vol.34 , pp. 296-306
    • van Laar, J.A.M.1    Rustum, Y.M.2    Ackland, S.P.3    van Groeningen, C.J.4    Peters, G.J.5
  • 80
    • 0022550606 scopus 로고
    • Steady-state nonlinear pharmacokinetics of 5-fluorouracil during hepatic arterial and intravenous infusions in cancer patients
    • Wagner J.G., Gyves J.W., Stetson P.L., Walker-Andrews S.C., Wollner I.S., Cochran M.K., Ensminger W.D. Steady-state nonlinear pharmacokinetics of 5-fluorouracil during hepatic arterial and intravenous infusions in cancer patients. Cancer Res. 1986, 46:1499-1506.
    • (1986) Cancer Res. , vol.46 , pp. 1499-1506
    • Wagner, J.G.1    Gyves, J.W.2    Stetson, P.L.3    Walker-Andrews, S.C.4    Wollner, I.S.5    Cochran, M.K.6    Ensminger, W.D.7
  • 81
    • 0019994436 scopus 로고
    • Successful treatment of HBs and HBeAg positive chronic liver disease: prolonged inhibition of viral replication by highly soluble adenine arabinoside 5'-monophosphate (ara-AMP)
    • Weller I.V.D., Bassendine M.F., Craxi A., Fowler M.J.F., Monjardino J., Thomas H.C., Sherlock S. Successful treatment of HBs and HBeAg positive chronic liver disease: prolonged inhibition of viral replication by highly soluble adenine arabinoside 5'-monophosphate (ara-AMP). Gut 1982, 23:717-723.
    • (1982) Gut , vol.23 , pp. 717-723
    • Weller, I.V.D.1    Bassendine, M.F.2    Craxi, A.3    Fowler, M.J.F.4    Monjardino, J.5    Thomas, H.C.6    Sherlock, S.7
  • 83
    • 0017817475 scopus 로고
    • Effect of reductive lactosamination on the hepatic uptake of bovine pancreatic ribonuclease A dimer
    • Wilson G. Effect of reductive lactosamination on the hepatic uptake of bovine pancreatic ribonuclease A dimer. J. Biol. Chem. 1978, 253:2070-2072.
    • (1978) J. Biol. Chem. , vol.253 , pp. 2070-2072
    • Wilson, G.1
  • 85
    • 0014186966 scopus 로고
    • A novel method for phosphorylation of nucleosides to 5'-nucleotides
    • Yoshikawa M., Kato T., Takeshini T. A novel method for phosphorylation of nucleosides to 5'-nucleotides. Tetrahedron Lett. 1967, 50:5065-5068.
    • (1967) Tetrahedron Lett. , vol.50 , pp. 5065-5068
    • Yoshikawa, M.1    Kato, T.2    Takeshini, T.3
  • 86
    • 0035075557 scopus 로고    scopus 로고
    • Efficacy and safety of lactosaminated human serum albumin-adenine arabinoside monophosphate in chronic hepatitis B patients non-responders to interferon therapy: a randomised clinical trial
    • Zarski J.P., Barange K., Souvignet C., Bertini M., Marcellin P., Tran A., Deugnier Y., Couzigou P., Plages A., Ambroise-Thomas P. Efficacy and safety of lactosaminated human serum albumin-adenine arabinoside monophosphate in chronic hepatitis B patients non-responders to interferon therapy: a randomised clinical trial. J. Hepatol. 2001, 34:487-488.
    • (2001) J. Hepatol. , vol.34 , pp. 487-488
    • Zarski, J.P.1    Barange, K.2    Souvignet, C.3    Bertini, M.4    Marcellin, P.5    Tran, A.6    Deugnier, Y.7    Couzigou, P.8    Plages, A.9    Ambroise-Thomas, P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.