Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin

Rapid Communications in Mass Spectrometry

Volumn 17, Issue 22, 2003, Pages 2503-2507

  Di Stefano, Giuseppina ^a   Tubaro, Michela ^b   Lanza, Marcella ^a   Boga, Carla ^a   Fiume, Luigi ^a   Traldi, Pietro ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINITY; AMINO ACIDS; CHEMICAL REACTIONS; CHEMOTHERAPY; ELECTROPHORESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUGARS;

ALKALINE PH; ANTI-CANCER AGENTS; CARRIER OF DRUGS; COUPLING REACTION; COVALENT LINKAGE; LACTOSE RESIDUE; MONOPHOSPHATES; PHYSICOCHEMICAL CHARACTERISTICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; SYNTHESISED;

MOLECULES;

DRUG CARRIER; FLOXURIDINE PHOSPHATE; HUMAN ALBUMIN; IMIDAZOLIDINE DERIVATIVE; LACTOSE; PEPTIDE;

ALKALINITY; ARTICLE; CANCER CHEMOTHERAPY; COVALENT BOND; LIVER METASTASIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; SYNTHESIS;

EID: 0242443366     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1232     Document Type: Article

References (24)

1. Di Stefano G, Lanza M, Busi C, Barbieri L, Fiume L. J. Pharm. Exp. Ther. 2002; 301: 638.
2. Di Stefano G, Busi C, Fiume L. Dig. Liver Dis. 2002; 34: 439.
3. Calabresi P, Chabner BA. Goodman and Gilman's The Pharmacological Basis of Therapeutics (9th edn). Mc Graw-Hill: New York, 1996; 1225-1287.
4. Gilbert HA, Kagan AN. Fundamental Aspects of Metastasis. North Holland Publishing: Amsterdam, 1976; 385-405.
5. Wilson G. J. Biol. Chem. 1978; 253: 2070.
6. Fiume L, Busi C, Mattioli A, Balboni PG, Barbanti-Brodano G. FEBS Lett. 1981; 129: 261.
7. Fiume L, Bassi B, Busi C, Mattioli A, Spinosa G. Biochem. Pharmacol. 1986; 35: 967.
8. Ponzetto A, Fiume L, Forzani B, Song SY, Busi C, Mattioli A, Spinelli C, Marinelli M, Smedile A, Chiaberghe E, Bonino F, Gervasi GB, Rapicetta M, Verme G. Hepatology 1991; 14: 16.
9. Fiume L, Torrani-Cerenzia MR, Bonino F, Busi C, Mattioli A, Brunetto MR, Chiaberge E, Verme G. Lancet 1988; 2: 13.
10. Torrani-Cerenzia MR, Fiume L, De Bernard Venon W, Lavezzo B, Brunetto MR, Ponzetto A, Di Stefano G, Busi C, Mattioli A, Gervasi GB, Bonino F, Verme G. Hepatology 1996; 23: 657.
11. Zarski JP, Barange K, Souvignet C, Bertini M, Marcellin P, Tran A, Deunier Y, Couzigou P, Plages A, Ambroise-Thomas P. J. Hepatol. 2001; 34: 486.
12. Strohmeyer T, Haugeberg G, Lierse W. J. Hepatol. 1987; 4: 181.
13. Haugeberg G, Strohmeyer T, Lierse W, Böcker W. J. Cancer Res. Clin. Oncol. 1988; 114: 415.
14. Schwartz BA, Gray GR. Arch. Biochem. Biophys. 1997; 181: 542.
15. Fiume L, Busi C, Di Stefano G, Mattioli A. Anal. Biochem. 1993; 212: 407.
16. Yoshikawa M, Kato T, Takenishi T. Tetrahedron Lett. 1967; 50: 5065.
17. Lohrmann R, Orgel LE. Tetrahedron 1978; 34: 853.
18. Ames BN. Methods Enzymol. 1966; 8: 115.
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. J. Biol. Chem. 1951; 193: 265.
20. Fiume L, Di Stefano G, Busi C, Mattioli A. Biochem. Pharmacol. 1994; 47: 643.
21. Weber K, Osborn M. J. Biol. Chem. 1969; 244: 4406.
22. Fiume L, Bassi B, Bongini A. Pharm. Acta Helv. 1988; 63: 137.
23. Baddiley J, Buchanan JG, Letters R. J. Chem. Soc. 1956; 2812.
24. Park JG, Collins JM, Gazdar AF, Allegra CJ, Steinberg SM, Greene RF, et al. J. Natl. Cancer Inst. 1988; 80: 1560.