메뉴 건너뛰기




Volumn 51, Issue SUPPL. 1, 2010, Pages

Mortality, attributable mortality, and clinical events as end points for clinical trials of ventilator-associated pneumonia and Hospital-acquired pneumonia

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL VENTILATION; CLINICAL FEATURE; CLINICAL TRIAL; CONFERENCE PAPER; CRITICAL ILLNESS; HOSPITAL ACQUIRED PNEUMONIA; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MORTALITY; PRIORITY JOURNAL; SAMPLE SIZE; SYSTEMATIC REVIEW; VENTILATOR ASSOCIATED PNEUMONIA; BIOASSAY; CLINICAL TRIAL (TOPIC); CROSS INFECTION; HOSPITAL; PNEUMONIA, BACTERIAL; PNEUMONIA, VENTILATOR-ASSOCIATED; SURVIVAL; TIME; TREATMENT OUTCOME;

EID: 77955681857     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/653060     Document Type: Conference Paper
Times cited : (170)

References (40)
  • 1
    • 0036209984 scopus 로고    scopus 로고
    • The design of randomized clinical trials in critically ill patients
    • Hebert P, Cook D, Wells G, et al. The design of randomized clinical trials in critically ill patients. Chest 2002; 121:1290-1300.
    • (2002) Chest , vol.121 , pp. 1290-1300
    • Hebert, P.1    Cook, D.2    Wells, G.3
  • 2
    • 0028877539 scopus 로고
    • Should morbidity replace mortality as an endpoint for clinical trials in intensive care?
    • Petros AJ, Marshall JC, van Saene HK. Should morbidity replace mortality as an endpoint for clinical trials in intensive care? Lancet 1995; 345:369-371.
    • (1995) Lancet , vol.345 , pp. 369-371
    • Petros, A.J.1    Marshall, J.C.2    Van Saene, H.K.3
  • 3
    • 35349001265 scopus 로고    scopus 로고
    • Attributable mortality due to nosocomial infections: A simple and useful application of mul-tistate models
    • Schumacher M, Wangler M, Wolkewitcz M, et al. Attributable mortality due to nosocomial infections: a simple and useful application of mul-tistate models. Methods Inf Med 2007; 46:595-600.
    • (2007) Methods Inf Med , vol.46 , pp. 595-600
    • Schumacher, M.1    Wangler, M.2    Wolkewitcz, M.3
  • 4
    • 0032531113 scopus 로고    scopus 로고
    • Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients
    • Cook DJ, Walter SD, Cook RJ, et al. Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 1998; 129:433-440.
    • (1998) Ann Intern Med , vol.129 , pp. 433-440
    • Cook, D.J.1    Walter, S.D.2    Cook, R.J.3
  • 5
    • 26444480583 scopus 로고    scopus 로고
    • Clinical and economic consequences of ventilator-associated pneumonia: A systematic review
    • Safdar N, Dezfulian C, Collard HR, et al. Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med 2005; 33(10):2184-2193.
    • (2005) Crit Care Med , vol.33 , Issue.10 , pp. 2184-2193
    • Safdar, N.1    Dezfulian, C.2    Collard, H.R.3
  • 6
    • 0345283255 scopus 로고    scopus 로고
    • Comparison of 8 vs 15 days of antibiotic therapy for ventilator- associated pneumonia in adults: A randomized trial
    • Chastre J, Wolff M, Fagon JY, et al. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA 2003; 290:2588-2598.
    • (2003) JAMA , vol.290 , pp. 2588-2598
    • Chastre, J.1    Wolff, M.2    Fagon, J.Y.3
  • 7
    • 33845693544 scopus 로고    scopus 로고
    • A randomized trial of diagnostic techniques for ventilator-associated pneumonia
    • A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 2006; 355(25):2619-2630.
    • (2006) N Engl J Med , vol.355 , Issue.25 , pp. 2619-2630
  • 8
    • 37549047587 scopus 로고    scopus 로고
    • Empiric antibiotic therapy for suspected ventilator-associated pneumonia: A systematic review and meta-analysis of randomized trials
    • Aarts MA, Hancock JN, Heyland D, et al. Empiric antibiotic therapy for suspected ventilator-associated pneumonia: a systematic review and meta-analysis of randomized trials. Crit Care Med 2008; 36:108-117.
    • (2008) Crit Care Med , vol.36 , pp. 108-117
    • Aarts, M.A.1    Hancock, J.N.2    Heyland, D.3
  • 9
    • 40849114633 scopus 로고    scopus 로고
    • Impact of inappropriate antibiotic therapy on mortality in patients with ventilator-associated pneumonia and blood stream infection: A meta-analysis
    • Kuti EL, Patel AA, Coleman CI. Impact of inappropriate antibiotic therapy on mortality in patients with ventilator-associated pneumonia and blood stream infection: a meta-analysis. J Crit Care 2008; 23: 91-100.
    • (2008) J Crit Care , vol.23 , pp. 91-100
    • Kuti, E.L.1    Patel, A.A.2    Coleman, C.I.3
  • 10
    • 63249128249 scopus 로고    scopus 로고
    • Intensive versus conventional glucose control in critically ill patients
    • Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009; 360: 1283-1297.
    • (2009) N Engl J Med , vol.360 , pp. 1283-1297
    • Finfer, S.1    Chittock, D.R.2    Su, S.Y.3
  • 11
    • 0034831601 scopus 로고    scopus 로고
    • The occurrence of ventilator-associated pneumonia in a community hospital: Risk factors and clinical outcomes
    • Ibrahim EH, Tracy L, Hill C, et al. The occurrence of ventilator-associated pneumonia in a community hospital: risk factors and clinical outcomes. Chest 2001; 120:555-561.
    • (2001) Chest , vol.120 , pp. 555-561
    • Ibrahim, E.H.1    Tracy, L.2    Hill, C.3
  • 12
    • 0035113105 scopus 로고    scopus 로고
    • Risk factors for nosocomial pneumonia in critically ill trauma patients
    • Tejada Artigas A, Bello Dronda S, Chacon Valles E, et al. Risk factors for nosocomial pneumonia in critically ill trauma patients. Crit Care Med 2001; 29:304-309.
    • (2001) Crit Care Med , vol.29 , pp. 304-309
    • Tejada Artigas, A.1    Bello Dronda, S.2    Chacon Valles, E.3
  • 13
    • 0036219421 scopus 로고    scopus 로고
    • Mortality associated with late-onset pneumonia in the intensive care unit: Results of a multi-center cohort study
    • Moine P, Timsit JF, De Lassence A, et al. Mortality associated with late-onset pneumonia in the intensive care unit: results of a multi-center cohort study. Intensive Care Med 2002; 28:154-163.
    • (2002) Intensive Care Med , vol.28 , pp. 154-163
    • Moine, P.1    Timsit, J.F.2    De Lassence, A.3
  • 14
    • 0344307472 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia at a tertiary-care center in a developing country: Incidence, microbiology, and susceptibility patterns of isolated microorganisms
    • Kanafani ZA, Kara L, Hayek S, et al. Ventilator-associated pneumonia at a tertiary-care center in a developing country: incidence, microbiology, and susceptibility patterns of isolated microorganisms. Infect Control Hosp Epidemiol 2003; 24:864-869.
    • (2003) Infect Control Hosp Epidemiol , vol.24 , pp. 864-869
    • Kanafani, Z.A.1    Kara, L.2    Hayek, S.3
  • 15
    • 0038662785 scopus 로고    scopus 로고
    • Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center
    • Warren DK, Shukla SJ, Olsen MA, et al. Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med 2003; 31:1312-1317.
    • (2003) Crit Care Med , vol.31 , pp. 1312-1317
    • Warren, D.K.1    Shukla, S.J.2    Olsen, M.A.3
  • 16
    • 17744382851 scopus 로고    scopus 로고
    • Incidence, risk factors and mortality of nosocomial pneumonia in intensive care units: A prospective study
    • Alp E, Guven M, Yildiz O, et al. Incidence, risk factors and mortality of nosocomial pneumonia in intensive care units: a prospective study. Ann Clin Microbiol Antimicrob 2004; 3:17.
    • (2004) Ann Clin Microbiol Antimicrob , vol.3 , pp. 17
    • Alp, E.1    Guven, M.2    Yildiz, O.3
  • 17
    • 26044473689 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia in a tertiary care ICU: Analysis of risk factors for acquisition and mortality
    • Myny D, Depuydt P, Colardyn F, et al. Ventilator-associated pneumonia in a tertiary care ICU: Analysis of risk factors for acquisition and mortality. Acta Clinica Belgica 2005; 60:114-121.
    • (2005) Acta Clinica Belgica , vol.60 , pp. 114-121
    • Myny, D.1    Depuydt, P.2    Colardyn, F.3
  • 18
    • 17444427115 scopus 로고    scopus 로고
    • Risk factors associated with development of ventilator associated pneumonia
    • Noor A, Hussain SF. Risk factors associated with development of ventilator associated pneumonia. J Coll Physicians Surg Pak 2005; 15: 92-95.
    • (2005) J Coll Physicians Surg Pak , vol.15 , pp. 92-95
    • Noor, A.1    Hussain, S.F.2
  • 19
    • 33646693385 scopus 로고    scopus 로고
    • Device-associated infection rate and mortality in intensive care units of 9 Colombian hospitals: Findings of the International Nosocomial Infection Control Consortium
    • Moreno CA, Rosenthal VD, Olarte N, et al. Device-associated infection rate and mortality in intensive care units of 9 Colombian hospitals: findings of the International Nosocomial Infection Control Consortium. Infect Control Hosp Epidemiol 2006; 27:349-356.
    • (2006) Infect Control Hosp Epidemiol , vol.27 , pp. 349-356
    • Moreno, C.A.1    Rosenthal, V.D.2    Olarte, N.3
  • 20
    • 34547533342 scopus 로고    scopus 로고
    • Nosocomial pneumonia in the ICU: A prospective cohort study
    • Hyllienmark P, Gardlund B, Persson JO, et al. Nosocomial pneumonia in the ICU: a prospective cohort study. Scand J Infect Dis 2007; 39: 676-682.
    • (2007) Scand J Infect Dis , vol.39 , pp. 676-682
    • Hyllienmark, P.1    Gardlund, B.2    Persson, J.O.3
  • 21
    • 33947574280 scopus 로고    scopus 로고
    • Incidence and outcomes of ventilator-associated pneumonia in Japanese intensive care units: The Japanese nosocomial infection surveillance system
    • Suka M, Yoshida K, Uno H, et al. Incidence and outcomes of ventilator-associated pneumonia in Japanese intensive care units: the Japanese nosocomial infection surveillance system. Infect Control Hosp Epidemiol 2007; 28:307-313.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 307-313
    • Suka, M.1    Yoshida, K.2    Uno, H.3
  • 22
    • 34547133731 scopus 로고    scopus 로고
    • Excess ICU mortality attributable to ventilator-associated pneumonia: The role of early vs late onset
    • Valles J, Pobo A, Garcia-Esquirol O, et al. Excess ICU mortality attributable to ventilator-associated pneumonia: the role of early vs late onset. Intensive Care Med 2007; 33:1363-1368.
    • (2007) Intensive Care Med , vol.33 , pp. 1363-1368
    • Valles, J.1    Pobo, A.2    Garcia-Esquirol, O.3
  • 23
    • 33846859315 scopus 로고    scopus 로고
    • Incidence and risk factors of device-associated infections and associated mortality at the intensive care in the Dutch surveillance system
    • van der Kooi TI, de Boer AS, Mannien J, et al. Incidence and risk factors of device-associated infections and associated mortality at the intensive care in the Dutch surveillance system. Intensive Care Med 2007; 33:271-278.
    • (2007) Intensive Care Med , vol.33 , pp. 271-278
    • Van Der Kooi, T.I.1    De Boer, A.S.2    Mannien, J.3
  • 24
    • 51249101524 scopus 로고    scopus 로고
    • Device-associated infection rates and mortality in intensive care units of Peruvian hospitals: Findings of the International Nosocomial Infection Control Consortium
    • Cuellar LE, Fernandez-Maldonado E, Rosenthal VD, et al. Device-associated infection rates and mortality in intensive care units of Peruvian hospitals: findings of the International Nosocomial Infection Control Consortium. Rev Panam Salud Publica 2008; 24:16-24.
    • (2008) Rev Panam Salud Publica , vol.24 , pp. 16-24
    • Cuellar, L.E.1    Fernandez-Maldonado, E.2    Rosenthal, V.D.3
  • 25
    • 48249107970 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia in an adult clinical-surgical intensive care unit of a Brazilian University Hospital: Incidence, risk factors, etiology, and antibiotic resistance
    • da Rocha L, de A, Vilela CAP, et al. Ventilator-associated pneumonia in an adult clinical-surgical intensive care unit of a Brazilian University Hospital: incidence, risk factors, etiology, and antibiotic resistance. Braz J Infect Dis 2008; 12:80-85.
    • (2008) Braz J Infect Dis , vol.12 , pp. 80-85
    • Da Rocha, L.1    De A Vilela Cap2
  • 26
    • 0027466159 scopus 로고
    • Nosocomial pneumonia in ventilated patients: A cohort study evaluating attributable mortality and hospital stay
    • Fagon JY, Chastre J, Hance AJ, et al. Nosocomial pneumonia in ventilated patients: a cohort study evaluating attributable mortality and hospital stay. Am J Med 1993; 94:281-288.
    • (1993) Am J Med , vol.94 , pp. 281-288
    • Fagon, J.Y.1    Chastre, J.2    Hance, A.J.3
  • 27
    • 0030028447 scopus 로고    scopus 로고
    • Pneumonia in intubated trauma patients. Microbiology and outcomes
    • Baker AM, Meredith JW, Haponik EF. Pneumonia in intubated trauma patients. Microbiology and outcomes. Am J Respir Crit Care Med 1996; 153:343-349.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 343-349
    • Baker, A.M.1    Meredith, J.W.2    Haponik, E.F.3
  • 28
    • 9344223929 scopus 로고    scopus 로고
    • Effect of ventilator-associated pneumonia on mortality and morbidity
    • Papazian L, Bregeon F, Thirion X, et al. Effect of ventilator-associated pneumonia on mortality and morbidity. Am J Respir Crit Care Med 1996; 154:91-97.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 91-97
    • Papazian, L.1    Bregeon, F.2    Thirion, X.3
  • 29
    • 0033032443 scopus 로고    scopus 로고
    • Effect of hospital-acquired ventilator-associated pneumonia on mortality of severe community-acquired pneumonia
    • Leroy O, Guilley J, Georges H, et al. Effect of hospital-acquired ventilator-associated pneumonia on mortality of severe community-acquired pneumonia. J Crit Care 1999; 14:12-19.
    • (1999) J Crit Care , vol.14 , pp. 12-19
    • Leroy, O.1    Guilley, J.2    Georges, H.3
  • 30
    • 0032939662 scopus 로고    scopus 로고
    • The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. the Canadian Critical Trials Group
    • Heyland DK, Cook DJ, Griffith L, et al. The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group. Am J Respir Crit Care Med 1999; 159:1249-1256.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1249-1256
    • Heyland, D.K.1    Cook, D.J.2    Griffith, L.3
  • 31
    • 0035675088 scopus 로고    scopus 로고
    • Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: A prospective case-control study
    • Bercault N, Boulain T. Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: a prospective case-control study. Crit Care Med 2001; 29:2303-2309.
    • (2001) Crit Care Med , vol.29 , pp. 2303-2309
    • Bercault, N.1    Boulain, T.2
  • 32
    • 0036924301 scopus 로고    scopus 로고
    • Epidemiology and outcomes of ventilator-associated pneumonia in a large US database
    • Rello J, Ollendorf DA, Oster G, et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest 2002; 122:2115-2121.
    • (2002) Chest , vol.122 , pp. 2115-2121
    • Rello, J.1    Ollendorf, D.A.2    Oster, G.3
  • 33
    • 0036345688 scopus 로고    scopus 로고
    • Influence on outcome of ventilator-associated pneumonia in multiple trauma patients with head trauma treated with selected digestive decontamination
    • Leone M, Bourgoin A, Giuly E, et al. Influence on outcome of ventilator-associated pneumonia in multiple trauma patients with head trauma treated with selected digestive decontamination. Crit Care Med 2002; 30:1741-1746.
    • (2002) Crit Care Med , vol.30 , pp. 1741-1746
    • Leone, M.1    Bourgoin, A.2    Giuly, E.3
  • 34
    • 11144236494 scopus 로고    scopus 로고
    • Impact of ventilator-associated pneumonia in patients with severe head injury
    • Rincon-Ferrari MD, Flores-Cordero JM, Leal-Noval SR, et al. Impact of ventilator-associated pneumonia in patients with severe head injury. J Trauma 2004; 57:1234-1240.
    • (2004) J Trauma , vol.57 , pp. 1234-1240
    • Rincon-Ferrari, M.D.1    Flores-Cordero, J.M.2    Leal-Noval, S.R.3
  • 35
    • 19044371559 scopus 로고    scopus 로고
    • Cost of a ventilator-associated pneumonia in a shock trauma intensive care unit
    • Cocanour CS, Ostrosky-Zeichner L, Peninger M, et al. Cost of a ventilator-associated pneumonia in a shock trauma intensive care unit. Surg Infect (Larchmt) 2005; 6(1):65-72.
    • (2005) Surg Infect (Larchmt) , vol.6 , Issue.1 , pp. 65-72
    • Cocanour, C.S.1    Ostrosky-Zeichner, L.2    Peninger, M.3
  • 36
    • 24944444103 scopus 로고    scopus 로고
    • Impact of ventilator-associated pneumonia on outcome in patients with COPD
    • Nseir S, Di Pompeo C, Soubrier S, et al. Impact of ventilator-associated pneumonia on outcome in patients with COPD. Chest 2005; 128: 1650-1656.
    • (2005) Chest , vol.128 , pp. 1650-1656
    • Nseir, S.1    Di Pompeo, C.2    Soubrier, S.3
  • 37
    • 29544442475 scopus 로고    scopus 로고
    • The effect of ventilator-associated pneumonia on the prognosis of head trauma patients
    • Kallel H, Chelly H, Bahloul M, et al. The effect of ventilator-associated pneumonia on the prognosis of head trauma patients. J Trauma 2005; 59:705-710.
    • (2005) J Trauma , vol.59 , pp. 705-710
    • Kallel, H.1    Chelly, H.2    Bahloul, M.3
  • 38
    • 33645804216 scopus 로고    scopus 로고
    • Risk and prognostic factors of ventilator-associated pneumonia in trauma patients
    • Cavalcanti M, Ferrer M, Ferrer R, et al. Risk and prognostic factors of ventilator-associated pneumonia in trauma patients. Crit Care Med 2006; 34:1067-1072.
    • (2006) Crit Care Med , vol.34 , pp. 1067-1072
    • Cavalcanti, M.1    Ferrer, M.2    Ferrer, R.3
  • 39
    • 33645967509 scopus 로고    scopus 로고
    • Incidence, risk factors, and outcome of ventilator-associated pneumonia
    • Tejerina E, Frutos-Vivar F, Restrepo MI, et al. Incidence, risk factors, and outcome of ventilator-associated pneumonia. J Crit Care 2006; 21:56-65.
    • (2006) J Crit Care , vol.21 , pp. 56-65
    • Tejerina, E.1    Frutos-Vivar, F.2    Restrepo, M.I.3
  • 40
    • 33744796216 scopus 로고    scopus 로고
    • Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infection
    • Beyersmann J, Gastmeier P, et al. Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infection. Infect Control Hosp Epidemiol 2006; 27:493-499.
    • (2006) Infect Control Hosp Epidemiol , vol.27 , pp. 493-499
    • Beyersmann, J.1    Gastmeier, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.