Coenzyme B12-dependent diol dehydratase is a potassium ion-requiring calcium metalloenzyme: Evidence that the substrate-coordinated metal ion is calcium

Biochemistry

Volumn 49, Issue 33, 2010, Pages 7210-7217

  Toraya, Tetsuo ^a,b   Honda, Susumu ^b,c   Mori, Koichi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c FUJIFILM Wako Pure Chemical Corporation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ADENINE RING; ADENOSYL GROUP; ELECTRON DENSITIES; METALLOENZYMES; POTASSIUM IONS; STABILIZING EFFECTS;

CATALYSIS; ENZYMES; METAL ANALYSIS; METAL IONS; METALS; SUBSTRATES; ULTRAFILTRATION;

CALCIUM;

ADENINE; CALCIUM; CALCIUM METALLOENZYME; COBAMAMIDE; DIOL DEHYDRATASE; EDETIC ACID; EGTAZIC ACID; HYDROLYASE; METAL ION; POTASSIUM; POTASSIUM ION; UNCLASSIFIED DRUG; CYANOCOBALAMIN; METAL; METALLOPROTEIN; PROPANEDIOL DEHYDRATASE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; PRIORITY JOURNAL; ULTRAFILTRATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYMOLOGY; KLEBSIELLA OXYTOCA; METABOLISM; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

CALCIUM; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; EDETIC ACID; EGTAZIC ACID; ENZYME STABILITY; KLEBSIELLA OXYTOCA; METALLOPROTEINS; METALS; MODELS, MOLECULAR; PROPANEDIOL DEHYDRATASE; PROTEIN BINDING; SUBSTRATE SPECIFICITY; VITAMIN B 12;

EID: 77955675459     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100561m     Document Type: Article

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