Synthesis and biological evaluation of oxoindolin-3-ylidene ethyl benzothiohydrazides as non-peptide TPO mimics

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 17, 2010, Pages 5062-5064

  Tang, Peng Cho ^a   Lu, He Jun ^a   Chen, Yi Qian ^a   Wang, Sheng Lan ^a   Zheng, Hao ^a   Wang, Li ^a  

^a Shanghai Hengrui Pharmaceuticals Co Ltd   (China)

Author keywords

c mpl; Non peptide; Thrombocytopenia; TPO

Indexed keywords

HYDRAZIDE DERIVATIVE; OXOINDOLIN 3 YLIDENE ETHYL BENZOTHIOHYDRAZIDE DERIVATIVE; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY;

CELL LINE; DRUG EVALUATION, PRECLINICAL; HUMANS; INDOLES; MOLECULAR MIMICRY; PEPTIDES; RECEPTORS, THROMBOPOIETIN;

EID: 77955665505     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.07.040     Document Type: Article

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