The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype

Journal of Gastroenterology

Volumn 45, Issue 7, 2010, Pages 721-731

  Jürgens, Matthias ^a   Brand, Stephan ^a   Laubender, Rüdiger P ^b   Seiderer, Julia ^a   Glas, Jürgen ^a,b,c   Wetzke, Martin ^d   Wagner, Johanna ^a   Pfennig, Simone ^a   Tillack, Cornelia ^a   Beigel, Florian ^a   Weidinger, Maria ^a   Schnitzler, Fabian ^a   Kreis, Martin E ^a   Göke, Burkhard ^a   Lohse, Peter ^b   Herrmann, Karin ^a   Ochsenkühn, Thomas ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Crohn's disease; Fistula; IL23R; Inflammatory bowel disease; NOD2 CARD15; Stenosis

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 23 RECEPTOR; IL23R PROTEIN, HUMAN; INTERLEUKIN RECEPTOR; NOD2 PROTEIN, HUMAN;

ARTICLE; COLONOSCOPY; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE DURATION; GENE MUTATION; GENOTYPE; HOMOZYGOSITY; HUMAN; INTESTINE FISTULA; INTESTINE STENOSIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; CONSTRICTION, PATHOLOGIC; GENETICS; INTESTINAL FISTULA; INTESTINAL OBSTRUCTION; MUTATION; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROSPECTIVE STUDY; STATISTICAL MODEL;

CONSTRICTION, PATHOLOGIC; CROHN DISEASE; GENOTYPE; HUMANS; INTESTINAL FISTULA; INTESTINAL OBSTRUCTION; LOGISTIC MODELS; MUTATION; NOD2 SIGNALING ADAPTOR PROTEIN; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECEPTORS, INTERLEUKIN; RETROSPECTIVE STUDIES;

EID: 77955664679     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-010-0231-7     Document Type: Article

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