Parallel anxiolytic-like and antinociceptive actions of diazepam in the anterior basolateral amygdala and dorsal periaqueductal gray

Brain Research

Volumn 1349, Issue , 2010, Pages 11-20

  Jiménez Velázquez, Guadalupe ^a   López Muñoz, Francisco Javier ^a   Fernández Guasti, Alonso ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Anterior basolateral amygdala; Anxiety nociception relationship; Diazepam; Dorsal periaqueductal gray; Pain induced functional impairment in the rat (PIFIR); Rat defensive burying behaviour

Indexed keywords

DIAZEPAM; URIC ACID;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; DRUG EFFECT; EXPERIMENTAL TEST; FUNCTIONAL DISEASE; HYPERALGESIA; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY;

AMYGDALA; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; AREA UNDER CURVE; BEHAVIOR, ANIMAL; DIAZEPAM; DISEASE MODELS, ANIMAL; MALE; PAIN; PERIAQUEDUCTAL GRAY; RATS; RATS, WISTAR; REACTION TIME; STATISTICS, NONPARAMETRIC; URIC ACID;

RATTUS;

EID: 77955657768     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.06.014     Document Type: Article

References (86)

1. R.D. Anbar, and S.C. Geisler Identification of children who may benefit from self-hypnosis at a pediatric pulmonary center Biol. Med. Cent. Pediatr. 5 2005 1 4
2. J. Andre, B. Zeau, M. Pohl, F. Cesselin, J.J. Benoliel, and C. Becker Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: behavioral and biochemical studies J. Neurosci. 25 2005 7896 7904
3. A.I. Basbaum, and H.L. Fields Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry Annu. Rev. Neurosci. 7 1984 309 338
4. J.F. Bernard, and R. Bandler Parallel circuits for emotional coping behaviour: new pieces in the puzzle J. Comp. Neurol. 401 1998 429 436
5. L. Bourgeais, L. Monconduit, L. Villanueva, and J.F. Bernard Parabrachial internal lateral neurons convey nociceptive messages from the deep laminas of the dorsal horn to the intralaminar thalamus J. Neurosci. 21 2001 2159 2165
6. C.H. Bueno, H. Zangrossi Jr., and M.V. Viana The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests Braz. J. Med. Biol. Res. 38 2005 1697 1701
7. P.R. Burghardt, and M.A. Wilson Microinjection of naltrexone into the central, but not the basolateral, amygdala blocks the anxiolytic effects of diazepam in the plus maze Neuropsychopharmacology 31 2006 1227 1240
8. Y. Carrasquilllo, and R.W. Gereau Hemispheric lateralization of a molecular signal for pain modulation in the amygdala Mol. Pain 4 2008 24
9. I.M. Conceição, M. Maiolini Jr., N. Mattia, M.A. Vital, B.R. Santos, S. Smaili, and R. Frussa-Filho Anxiety-induced antinociception in the mouse Braz. J. Med. Biol. Res. 25 1992 831 834
10. B.G. Covino, R. Dubner, J. Gybels, H.W. Kosterlitz, J.C. Liebeskind, R.A. Sternbach, L. Vyclicky, H. Yamamura, and M. Zimmermann Ethical standards for investigations of experimental pain in animals Pain 9 1980 141 143
11. G. Deng, and B.R. Cassileth Integrative oncology: complementary therapies for pain, anxiety, and mood disturbance CA Cancer J. Clin. 55 2005 109 116
12. L.M. dos Reis, and A. Canto de Souza Intra-periaqueductal gray matter injections of midazolam fail to alter anxiety in plus-maze experienced mice Brain Res. 1231 2008 93 102
13. M.S. Fanselow, and J.J. Kim The benzodiazepine inverse agonist DMCM as an unconditional stimulus for fear-induced analgesia: implications for the role of GABAA receptors in fear-related behavior Behav. Neurosci. 106 1992 336 344
14. A. Fernández-Guasti, R. Reyes, L. Martínez-Mota, and F.J. López-Muñoz Influence of inflammatory nociception on the anxiolytic-like effect of diazepam and buspirone in rats Psychopharmacology 180 2005 399 407
15. Y.J. Gao, W.H. Ren, Y.Q. Zhang, and Z.Q. Zhao Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats Pain 110 2004 343 353
16. C. Gauriau, and J.F. Bernard Pain pathway and parabrachial circuits in the rat Exp. Physiol. 87 2002 251 258
17. F.G. Graeff Serotonin, the periaqueductal gray and panic Neurosci. Biobehav. Rev. 28 2004 239 259
18. F.G. Graeff, M.C. Silveira, R.L. Nogueira, E.A. Audi, and R.M. Oliveira Role of the amygdala and periaqueductal gray in anxiety and panic Behav. Brain Res. 58 1993 123 131
19. D.A. Gries, G.A. Condouris, Z. Shey, and M. Houpt Anxiolytic-like action in mice treated with nitrous oxide and oral triazolam or diazepam Life Sci. 76 2005 1667 1674
20. S. Haas, H.M. Emrich, and H. Beckmann Analgesic and euphoric effects of high dose diazepam in schizophrenia Neuropsychobiology 8 1982 123 128
21. M.W. Hale, A.J. Bouwknecht, F. Spiga, A. Shekhar, and C.A. Lowry Exposure to high-and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex Brain Res. Bull. 71 2006 174 182
22. J.A. Harris Descending antinociceptive mechanisms in the brainstem: their role in the animal's defensive system J. Physiol. Paris 90 1996 15 25
23. J.A. Harris, and R.F. Westbrook Effects of benzodiazepine microinjection into the amygdala or periaqueductal gray upon the expression of conditioned fear and hypoalgesia in rats Behav. Neurosci. 109 1995 295 304
24. F.J. Helmstetter Stress-induced hypoalgesia and defensive freezing are attenuated by application of diazepam to the amygdala Pharmacol. Biochem. Behav. 44 1993 433 438
25. H. Hodges, S. Green, and B. Glenn Evidence that the amygdala is involved in benzodiazepine and serotonergic effects on punished responding but not on discrimination Psychopharmacology 92 1987 491 504
26. B.A. Huyser, and J.C. Parker Negative affect and pain in arthritis Rheum. Dis. Clin. North Am. 25 1999 105 121
27. L. Jasmin, A.R. Burkey, J.P. Card, and A.I. Basbaum Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat J. Neurosci. 17 1997 3751 3765
28. S.A. Janssen, and A. Arntz No interactive effect of naltrexone and benzodiazepines on pain during phobic fear Behav. Res. Ther. 37 1999 77 86
29. G. Ji, Y. Fu, K.A. Ruppert, and V. Neugebauer Pain-related anxiety-like behavior requires CRFI receptors into the amygdala Mol. Pain 3 2007 13
30. G. Jiménez-Velázquez, A. Fernández-Guasti, and F.J. López-Muñoz Influence of pharmacologically-induced experimental anxiety on nociception and antinociception in rats Eur. J. Pharmacol. 547 2006 83 91
31. G. Jiménez-Velázquez, F.J. López-Muñoz, and A. Fernández-Guasti Participation of the GABA/benzodiazepine receptor and the NO-cyclicGMP pathway in the "antinociceptive-like effects" of diazepam Pharmacol. Biochem. Behav. 91 2008 128 133
32. E. Jørum The analgesic effect of peripheral nerve stimulation in various tests of nociception in rats Acta Physiol. Scand. 133 1988 131 138
33. K.A. Keay, and R. Bandler Parallel circuits mediating distinct emotional coping reactions to different types of stress Neurosci. Biobehav. Rev. 25 2001 669 678
34. I.B. Kinscheck, L.R. Watkins, and D.J. Mayer Fear is not critical to classically conditioned analgesia: the effects of periaqueductal gray lesions and administration of chlordiazepoxide Brain Res. 298 1984 33 44
35. J. Knabl, U.B. Zeilhofer, F. Crestani, U. Rudolph, and H.U. Zeilhofer Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice Pain 141 2009 233 238
36. G.F. Koob, S.C. Heinrichs, and K. Britton Animal models of anxiety disorders The American psychiatric Press textbook of psychopharmacology 2nd edition 1998 133 144
37. J.E. LeDoux Emotion circuits in the brain Annu. Rev. Neurosci. 23 2000 155 184
38. C. Lee, and R.J. Rodgers Antinociceptive effects of elevated plus-maze exposure: influence of opiate receptor manipulations Psychopharmacology 102 1990 507 513
39. R. Levandovski, M.B. Ferreira, M.P. Hidalgo, C.A. Konrath, D.L. da Silva, and W. Caumo Impact of preoperative anxiolytic on surgical site infection in patients undergoing abdominal hysterectomy Am. J. Infect. Control 36 2008 718 726
40. F.J. López-Muñoz, G. Castañeda-Hernández, J. Villareal, and L.A. Salazar A new model to assess analgesic activity: pain-induced functional impairment in the rat (PIFIR) Drug Dev. Res. 28 1993 169 175
41. T.A. Lovick Pro-nociceptive action of cholecystokinin in the periaqueductal grey: a role in neuropathic and anxiety-induced hyperalgesic states Neurosci. Biobehav. Rev. 32 2008 852 862
42. M.E. Martenson, J.S. Cetasa, and M.M. Heinricherab A possible neural basis for stress-induced hyperalgesia Pain 142 2009 236 244
43. J. Menard, and D. Treit Effects of centrally administered anxiolytic compounds in animal models of anxiety Neurosci. Biobehav. Rev. 23 1999 591 613
44. J. Mendes-Gomes, and R.L. Nunes de Souza Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periacueductal grey in mice Brain Res. 1047 2005 97 104
45. J. Mendes-Gomes, and R.L. Nunes de Souza Anxiolytic-like effects produced by bilateral lesion of the periaqueductal gray in mice: influence of concurrent nociceptive stimulation Behav. Brain Res. 203 2009 180 187
46. M.M. Morgan, A. Depaulis, and J.C. Liebeskind Periaqueductal gray matter stimulation produced analgesia in the pentobarbital anesthetized rat Proc. West. Pharmacol. Soc. 28 1985 161 163
47. M.M. Morgan, A. Depaulis, and J.C. Liebeskind Diazepam dissociates the analgesic and aversive effects of periaqueductal gray stimulation in the rat Brain Res. 423 1987 395 398 (Pubitemid 17157198)
48. V. Motta, and M.L. Brandao Aversive and antiaversive effects o morphine in the periacueductal gray of rats submitted to the elevated plus-maze test Pharmacol. Biochem. Behav. 44 1993 119 125
49. V. Neugebauer, and W. Li Differential sensitization of amygdala neurons to afferents inputs in a model of arthritic pain J. Neurophysiol. 89 2003 716 727
50. V. Neugebauer, W. Li, G.C. Bird, and J.S. Han The amygdala and persistent pain Neuroscientist 10 2004 221 234
51. D.L. Niehoff, and M.J. Kuhar Benzodiazepine receptors: localization in rat amygdala J. Neurosci. 3 1983 2091 2097
52. M.R. Nott, P.M. Jameson, and S.A. Julious Diazepam for relief of irrigation pain after transurethral resection of the prostate Eur. J. Anaesthesiol. 14 1997 197 200
53. R.L. Nunes de Souza, A. Canto de Souza, M. da Costa, R.V. Fornari, F.G. Graeff, and I.R. Pelá Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam Psychopharmacology 150 2000 300 310
54. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates Fourth edition 1998 Academic Press Australia
55. M. Pérez de la Mora, A. Gallegos-Cari, Y. Arizmendi-García, D. Marcelino, and K. Fuxe Role of dopamine receptor mechanisms in the amygdaloid modulation of fear and anxiety: structural and functional analysis Prog. Neurobiol. 90 2010 198 216
56. C. Pesold, and D. Treit The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines Brain Res. 638 1994 295 301
57. C. Pesold, and D. Treit The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines Brain Res. 671 1995 213 221
58. E.N. Petersen, C. Braestrup, and J. Scheel-Kruger Evidence that the anticonflict effect of midazolam in amygdala is mediated by the specific benzodiazepine receptors Neurosci. Lett. 53 1985 285 288
59. D.D. Price Central neural mechanisms that interrelate sensory and affective dimensions of pain Mol. Interv. 2 2002 392 403
60. L. Quintero, M.C. Cuesta, J.A. Silva, J.L. Arcaya, L. Pinerua-Suhaibar, W. Maixner, and H. Suarez-Roca Repeated swim stress increases pain-induced expression of c-Fos in the rat lumbar cord Brain Res. 965 2003 259 268
61. P. Rainville, G.H. Duncan, D.D. Price, B. Carrier, and M.C. Bushnell Pain affect encoded in human anterior cingulate but not somatosensory cortex Science 277 1997 968 970
62. P. Rainville, B. Carrier, R.K. Hofbauer, M.C. Bushnell, and G.H. Duncan Dissociation of sensory and affective dimensions of pain using hypnotic modulation Pain 82 1999 159 171
63. S. Reddy, and R.B. Patt The benzodiazepines as adjuvant analgesics J. Pain Sympton Manage. 9 1994 510 514
64. R.J. Rodgers, and J.I. Randall Benzodiazepines ligands, nociception and "defeat" analgesia in male mice Psychopharmacology 91 1987 305 315
65. R.J. Rodgers, C. Lee, and J.K. Shepherd Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience Psychopharmacology 106 1992 102 110
66. J.H. Rosland, S. Hunskaar, and K. Hole The effect of diazepam on nociception in mice Pharmacol. Toxicol. 61 1987 111 115
67. M. Rowland, and N.T. Tozer Clinical Pharmacokinetics: Concepts and Applications 1989 Lea and Febiger Philadelphia
68. A.S. Russo, F.S. Guimaraes, J.C. De Aguiar, and F.G. Graeff Role of benzodiazepine receptor located in the dorsal periacueductal gray of rats in anxiety Psychopharmacology 110 1993 198 202
69. W. Sieghart Pharmacology of Benzodiazepine receptor: an update J. Psychiatry Neurosci. 9 1994 24 29
70. Y. Smith, J.F. Paré, and D. Paré Differential innervation of parvalbumin-immunoreactive interneurons of the basolateral amygdaloid complex by cortical and intrinsic inputs J. Comp. Neurol. 416 2000 496 508
71. Y.G. Sun, Y.J. Gao, Z.Q. Zhao, B. Huang, J. Yin, G.A. Taylor, and Z.F. Chen Involvement of P311 in the affective, but not in the sensory component of pain Mol. Pain 4 2008 23
72. S. Talarek, and S. Fidecka Role of nitric oxide in benzodiazepines- induced antinociception in mice Pol. J. Pharmacol. 54 2002 27 34
73. M. Tanaka, M. Yoshida, H. Emoto, and H. Ishii Noradrenaline system in the hypothalamus, amygdala and locus coeruleus are involved in the provocation of anxiety: basic studies Eur. J. Pharmacol. 405 2000 397 406
74. S. Tanimoto, T. Nakagawa, Y. Yamauchi, M. Minami, and M. Satoh Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats Eur. J. Neurosci. 18 2003 2343 2350
75. M.A. Tatsuo, J.V. Salgado, C.M. Yokoro, I.D.G. Duarte, and J.N. Francischi Midazolam-induced hyperalgesia in rats: modulation via GABAA receptors at supraspinal level Eur. J. Pharmacol. 370 1999 9 15
76. S.A. Tershner, and F.J. Helmstetter Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray Brain Res. 865 2000 17 26
77. S.R. Thomas, M.E. Lewis, and S.D. Iversen Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdala complex of the rat Brain Res. 342 1985 85 90
78. D. Treit Animal models for study of anti-anxiety agents: a review Neurosci. Biobehav. Rev. 9 1985 203 222
79. D. Treit A comparison of anxiolytic and nonanxiolytic agents in the shock-probe/buying test for anxiolytics Pharmacol. Biochem. Behav. 36 1990 23 205
80. H. Vanegas, and H.G. Schaible Descending control of persistent pain: inhibitory or facilitatory? Brain Res. Rev. 46 2004 295 309
81. L.F. Vendruscolo, F.A. Pamplona, and R.N. Takahashi Strain and sex defferences in the expression of nociceptive behavior and stress-induced analgesia in rats Brain Res. 1033 2004 277 283
82. C. Vidal, and J. Jacob Hyperalgesia induced by non-noxious stress in the rat Neurosci. Lett. 32 1982 75 80
83. F. Zambotti, N. Zonta, R. Tammiso, P. Ferraio, B. Hafner, and P. Mantegazza Reversal of the effect of centrally administered diazepam on morphine antinociception by specific (Ro 15-1788 and Ro 15-3505) and non-specific (bicuculline and caffeine) benzodiazepine antoagonists Naunyn Schmiedebergs Arch. Pharmacol. 333 1986 43 46
84. F. Zambotti, N. Zonta, R. Tammiso, F. Conci, B. Hanfer, L. Zecca, and P. Ferrario-Mantegazza Effects of diazepam on nociception in rats Naunyn Schmiedebergs Arch. Pharmacol. 344 1991 84 89
85. J. Zanoveli, R.L. Nogueira, and H. Zangrossi Serotonin in the dorsal periqueductal gray modulates inhibitory avoidance and one-way escape behaviors in the elevated T-maze Eur. J. Pharmacol. 473 2003 153 161
86. M. Zimmermann Ethical guidelines for investigations of experimental pain in conscious animals Pain 16 1983 109 110