Development of an aggregation assay to screen FimH antagonists

Journal of Microbiological Methods

Volumn 82, Issue 3, 2010, Pages 249-255

  Abgottspon, Daniela ^a,b   Rölli, Gina ^a,b   Hosch, Lucie ^c   Steinhuber, Andrea ^a   Jiang, Xiaohua ^a   Schwardt, Oliver ^a   Cutting, Brian ^a   Smiesko, Martin ^a   Jenal, Urs ^c   Ernst, Beat ^a   Trampuz, Andrej ^b,d  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Aggregation; E. coli; FimH antagonist; Type 1 pili; Urinary tract infection (UTI)

Indexed keywords

2 CHLORO 4 NITROPHENYL ALPHA DEXTRO MANNOPYRANOSIDE; 2 CHLORO 4 [N (2 ETHOXY 3,4 DIOXOCYCLOBUT 1 ENYL)AMINO]PHENYL ALPHA DEXTRO MANNOPYRANOSIDE; 4 NITROPHENYL ALPHA DEXTRO MANNOPYRANOSIDE; ALPHA MANNOSIDASE; ALPHA METHYL MANNOSIDE; ANTIINFECTIVE AGENT; FIMBRIA H PROTEIN; FIMBRIA PROTEIN; GALACTOSE; MANNOSE; N HEPTYL ALPHA DEXTRO MANNOPYRANOSIDE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DELETION MUTANT; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; ERYTHROCYTE AGGREGATION; ESCHERICHIA COLI; GUINEA PIG; IC 50; INCUBATION TIME; NONHUMAN; PRIORITY JOURNAL; YEAST CELL;

CANDIDA ALBICANS; CAVIA; ESCHERICHIA COLI;

EID: 77955655327     PISSN: 01677012     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mimet.2010.06.015     Document Type: Article

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