메뉴 건너뛰기




Volumn 225, Issue 1-2, 2010, Pages 52-61

Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis

Author keywords

APCs; EAE; RTLs; Tolerance

Indexed keywords

CD11B ANTIGEN; RTL 401; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 77955653379     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.04.013     Document Type: Article
Times cited : (25)

References (23)
  • 1
    • 0029451821 scopus 로고
    • The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis
    • Bauer J., Huitinga I., Zhao W., Lassmann H., Hickey W.F., Dijkstra C.D. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia 1995, 15:437-446.
    • (1995) Glia , vol.15 , pp. 437-446
    • Bauer, J.1    Huitinga, I.2    Zhao, W.3    Lassmann, H.4    Hickey, W.F.5    Dijkstra, C.D.6
  • 2
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. 1997, 75:165-173.
    • (1997) J. Mol. Med. , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 3
    • 27744451956 scopus 로고    scopus 로고
    • Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis
    • Bullard D.C., Hu X., Schoeb T.R., Axtell R.C., Raman C., Barnum S.R. Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis. J. Immunol. 2005, 175:6327-6333.
    • (2005) J. Immunol. , vol.175 , pp. 6327-6333
    • Bullard, D.C.1    Hu, X.2    Schoeb, T.R.3    Axtell, R.C.4    Raman, C.5    Barnum, S.R.6
  • 4
    • 0032402243 scopus 로고    scopus 로고
    • Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis
    • Burrows G.G., Bebo B.F., Adlard K.L., Vandenbark A.A., Offner H. Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis. J. Immunol. 1998, 161:5987-5996.
    • (1998) J. Immunol. , vol.161 , pp. 5987-5996
    • Burrows, G.G.1    Bebo, B.F.2    Adlard, K.L.3    Vandenbark, A.A.4    Offner, H.5
  • 9
    • 0028856219 scopus 로고
    • Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis
    • Gordon E.J., Myers K.J., Dougherty J.P., Rosen H., Ron Y. Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 1995, 62:153-160.
    • (1995) J. Neuroimmunol. , vol.62 , pp. 153-160
    • Gordon, E.J.1    Myers, K.J.2    Dougherty, J.P.3    Rosen, H.4    Ron, Y.5
  • 10
    • 12144289376 scopus 로고    scopus 로고
    • Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch
    • Huan J., Subramanian S., Jones R., Rich C., Link J., Mooney J., Bourdette D.N., Vandenbark A.A., Burrows G.G., Offner H. Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch. J. Immunol. 2004, 172:4556-4566.
    • (2004) J. Immunol. , vol.172 , pp. 4556-4566
    • Huan, J.1    Subramanian, S.2    Jones, R.3    Rich, C.4    Link, J.5    Mooney, J.6    Bourdette, D.N.7    Vandenbark, A.A.8    Burrows, G.G.9    Offner, H.10
  • 11
    • 77955653646 scopus 로고    scopus 로고
    • Partial MHC class II molecules preferentially bind to B cells
    • Link J. Partial MHC class II molecules preferentially bind to B cells. J. Immunol. 2007, 78.
    • (2007) J. Immunol. , vol.78
    • Link, J.1
  • 12
    • 33947152923 scopus 로고    scopus 로고
    • Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice
    • Link J.M., Rich C.M., Korat M., Burrows G.G., Offner H., Vandenbark A.A. Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice. Clin. Immunol. 2007, 123:95-104.
    • (2007) Clin. Immunol. , vol.123 , pp. 95-104
    • Link, J.M.1    Rich, C.M.2    Korat, M.3    Burrows, G.G.4    Offner, H.5    Vandenbark, A.A.6
  • 13
    • 33750490450 scopus 로고    scopus 로고
    • A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist
    • Nicholson G.C., Tennant R.C., Carpenter D.C., Sarau H.M., Kon O.M., Barnes P.J., Salmon M., Vessey R.S., Tal-Singer R., Hansel T.T. A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist. Pulm. Pharmacol. Ther. 2007, 20:52-59.
    • (2007) Pulm. Pharmacol. Ther. , vol.20 , pp. 52-59
    • Nicholson, G.C.1    Tennant, R.C.2    Carpenter, D.C.3    Sarau, H.M.4    Kon, O.M.5    Barnes, P.J.6    Salmon, M.7    Vessey, R.S.8    Tal-Singer, R.9    Hansel, T.T.10
  • 14
    • 24744452162 scopus 로고    scopus 로고
    • Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury
    • Offner H., Subramanian S., Wang C., Afentoulis M., Vandenbark A.A., Huan J., Burrows G.G. Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury. J. Immunol. 2005, 175:4103-4111.
    • (2005) J. Immunol. , vol.175 , pp. 4103-4111
    • Offner, H.1    Subramanian, S.2    Wang, C.3    Afentoulis, M.4    Vandenbark, A.A.5    Huan, J.6    Burrows, G.G.7
  • 15
    • 57349172905 scopus 로고    scopus 로고
    • Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis
    • Offner H., Sinha S., Wang C., Burrows G.G., Vandenbark A.A. Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis. Rev. Neurosci. 2008, 19:327-339.
    • (2008) Rev. Neurosci. , vol.19 , pp. 327-339
    • Offner, H.1    Sinha, S.2    Wang, C.3    Burrows, G.G.4    Vandenbark, A.A.5
  • 16
    • 0033156054 scopus 로고    scopus 로고
    • Lipopolysaccharide enhances FcgammaR-dependent functions in vivo through CD11b/CD18 up-regulation
    • Rubel C., Miliani De Marval P., Vermeulen M., Isturiz M.A., Palermo M.S. Lipopolysaccharide enhances FcgammaR-dependent functions in vivo through CD11b/CD18 up-regulation. Immunology 1999, 97:429-437.
    • (1999) Immunology , vol.97 , pp. 429-437
    • Rubel, C.1    Miliani De Marval, P.2    Vermeulen, M.3    Isturiz, M.A.4    Palermo, M.S.5
  • 17
    • 36248944158 scopus 로고    scopus 로고
    • A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS
    • Sinha S., Subramanian S., Proctor T.M., Kaler L.J., Grafe M., Dahan R., Huan J., Vandenbark A.A., Burrows G.G., Offner H. A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS. J. Neurosci. 2007, 27:12531-12539.
    • (2007) J. Neurosci. , vol.27 , pp. 12531-12539
    • Sinha, S.1    Subramanian, S.2    Proctor, T.M.3    Kaler, L.J.4    Grafe, M.5    Dahan, R.6    Huan, J.7    Vandenbark, A.A.8    Burrows, G.G.9    Offner, H.10
  • 18
    • 64849084182 scopus 로고    scopus 로고
    • Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand
    • Sinha S., Subramanian S., Miller L., Proctor T.M., Roberts C., Burrows G.G., Vandenbark A.A., Offner H. Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand. J. Neurosci. 2009, 29:3816-3823.
    • (2009) J. Neurosci. , vol.29 , pp. 3816-3823
    • Sinha, S.1    Subramanian, S.2    Miller, L.3    Proctor, T.M.4    Roberts, C.5    Burrows, G.G.6    Vandenbark, A.A.7    Offner, H.8
  • 20
    • 0037869060 scopus 로고    scopus 로고
    • Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice
    • Vandenbark A.A., Rich C., Mooney J., Zamora A., Wang C., Huan J., Fugger L., Offner H., Jones R., Burrows G.G. Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice. J. Immunol. 2003, 171:127-133.
    • (2003) J. Immunol. , vol.171 , pp. 127-133
    • Vandenbark, A.A.1    Rich, C.2    Mooney, J.3    Zamora, A.4    Wang, C.5    Huan, J.6    Fugger, L.7    Offner, H.8    Jones, R.9    Burrows, G.G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.