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Volumn 7, Issue 49, 2010, Pages 1157-1170

Simulation of lung alveolar epithelial wound healing in vitro

Author keywords

Acute lung injury; Alveolar wound repair; Discrete event simulation; Multi agent model

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; CELL PROLIFERATION; DISCRETE EVENT SIMULATION; MONOLAYERS; SIGNALING;

EID: 77955632246     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2010.0041     Document Type: Article
Times cited : (10)

References (50)
  • 1
    • 0001287861 scopus 로고
    • Observations on the social behaviour of cells in tissue culture. II. Monolayering of fibroblasts
    • doi:10.1016/0014-4827(54)90176-7
    • Abercrombie, M. & Heaysman, J. E. M. 1954 Observations on the social behaviour of cells in tissue culture. II. Monolayering of fibroblasts. Exp. Cell Res. 6, 293-306. (doi:10.1016/0014-4827(54)90176-7)
    • (1954) Exp. Cell Res. , vol.6 , pp. 293-306
    • Abercrombie, M.1    Heaysman, J.E.M.2
  • 2
    • 0009760979 scopus 로고    scopus 로고
    • Parenchymal changes
    • eds R. G. Crystal, J. B. West, P. J. Barnes & E. R. Weibel, Philadelphia, PA: Lippincott-Raven Publishers
    • Bachofen, M. & Bachofen, H. 1997 Parenchymal changes. In The lung: scientific foundations (eds R. G. Crystal, J. B. West, P. J. Barnes & E. R. Weibel), pp. 2499-2508. Philadelphia, PA: Lippincott-Raven Publishers.
    • (1997) The Lung: Scientific Foundations , pp. 2499-2508
    • Bachofen, M.1    Bachofen, H.2
  • 3
    • 34047105209 scopus 로고    scopus 로고
    • Sheet migration by wounded monolayers as an emergent property of single-cell dynamics
    • DOI 10.1242/jcs.03395
    • Bindschadler, M. & McGrath, J. L. 2007 Sheet migration by wounded monolayers as an emergent property of single-cell dynamics. J. Cell Sci. 120, 876-884. (doi:10.1242/jcs.03395) (Pubitemid 46523489)
    • (2007) Journal of Cell Science , vol.120 , Issue.5 , pp. 876-884
    • Bindschadler, M.1    McGrath, J.L.2
  • 4
    • 33847688542 scopus 로고    scopus 로고
    • Multi-scale modeling of a wound-healing cell migration assay
    • doi:10.1016/j.jtbi.2006.10.024
    • Cai, A. Q., Landman, K. A. & Hughes, B. D. 2007 Multi-scale modeling of a wound-healing cell migration assay. J. Theor. Biol. 245, 576-594. (doi:10.1016/j.jtbi.2006.10.024)
    • (2007) J. Theor. Biol. , vol.245 , pp. 576-594
    • Cai, A.Q.1    Landman, K.A.2    Hughes, B.D.3
  • 5
    • 0002805319 scopus 로고    scopus 로고
    • Biology of acute injury
    • eds R. G. Crystal, J. B. West, P. J. Barnes & E. R. Weibel, Philadelphia, PA: Lippincott-Raven Publishers
    • Canonico, A. E. & Brigham, K. L. 1997 Biology of acute injury. In The lung: scientific foundations (eds R. G. Crystal, J. B. West, P. J. Barnes & E. R. Weibel), pp. 2475-2498. Philadelphia, PA: Lippincott-Raven Publishers.
    • (1997) The Lung: Scientific Foundations , pp. 2475-2498
    • Canonico, A.E.1    Brigham, K.L.2
  • 6
    • 59149104281 scopus 로고    scopus 로고
    • The formation of epithelial tubes
    • doi:10.1242/jcs.037887
    • Chung, S. Y. & Andrew, D. J. 2008 The formation of epithelial tubes. J. Cell Sci. 121, 3501-3504. (doi:10.1242/jcs.037887)
    • (2008) J. Cell Sci. , vol.121 , pp. 3501-3504
    • Chung, S.Y.1    Andrew, D.J.2
  • 7
    • 0033592238 scopus 로고    scopus 로고
    • Mathematical modelling of extracellular matrix dynamics using discrete cells: Fiber orientation and tissue regeneration
    • doi:10.1006/jtbi.1999.0971
    • Dallon, J. C., Sherratt, J. A. & Maini, P. K. 1999 Mathematical modelling of extracellular matrix dynamics using discrete cells: fiber orientation and tissue regeneration. J. Theor. Biol. 199, 449-471. (doi:10.1006/jtbi.1999.0971)
    • (1999) J. Theor. Biol. , vol.199 , pp. 449-471
    • Dallon, J.C.1    Sherratt, J.A.2    Maini, P.K.3
  • 8
    • 43349104741 scopus 로고    scopus 로고
    • Advances in mechanisms of repair and remodelling in acute lung injury
    • doi:10.1007/s00134-007-0963-x
    • Dos Santos, C. C. 2008 Advances in mechanisms of repair and remodelling in acute lung injury. Intensive Care Med. 34, 619-630. (doi:10.1007/s00134-007- 0963-x)
    • (2008) Intensive Care Med. , vol.34 , pp. 619-630
    • Dos Santos, C.C.1
  • 9
    • 33644626234 scopus 로고    scopus 로고
    • B-Catenin in the fibroproliferative response to acute lung injury
    • doi:10.1165/rcmb.2005-0277OC
    • Douglas, I. S., Diaz del Valle, F., Winn, R. A. & Voelkel, N. F. 2006 b-Catenin in the fibroproliferative response to acute lung injury. Am. J. Respir. Cell. Mol. Biol. 34, 274-285. (doi:10.1165/rcmb.2005-0277OC)
    • (2006) Am. J. Respir. Cell. Mol. Biol. , vol.34 , pp. 274-285
    • Douglas, I.S.1    Diaz Del Valle, F.2    Winn, R.A.3    Voelkel, N.F.4
  • 10
    • 14044271408 scopus 로고    scopus 로고
    • Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement
    • DOI 10.1242/jcs.01577
    • Farooqui, R. & Fenteany, G. 2005 Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet migration. J. Cell Sci. 118, 51-63. (doi:10.1242/jcs.01577) (Pubitemid 40277104)
    • (2005) Journal of Cell Science , vol.118 , Issue.1 , pp. 51-63
    • Farooqui, R.1    Fenteany, G.2
  • 11
    • 36049044199 scopus 로고    scopus 로고
    • Executable cell biology
    • doi:10.1038/nbt1356
    • Fisher, J. & Henzinger, T. A. 2007 Executable cell biology. Nat. Biotechnol. 25, 1239-1249. (doi:10.1038/nbt1356)
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1239-1249
    • Fisher, J.1    Henzinger, T.A.2
  • 12
    • 0000268135 scopus 로고
    • The wave of advance of advantageous genes
    • doi:10.1038/nbt1356
    • Fisher, R. A. 1937 The wave of advance of advantageous genes. Ann. Eugenics 7, 353-369. (doi:10.1038/nbt1356)
    • (1937) Ann. Eugenics , vol.7 , pp. 353-369
    • Fisher, R.A.1
  • 13
  • 14
    • 0034987933 scopus 로고    scopus 로고
    • Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1 β-dependent mechanism
    • Geiser, T., Atabai, K., Jarreau, P. H., Ware, L. B., Pugin, J. & Matthay, M. A. 2001 Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1 β-dependent mechanism. Am. J. Respir. Crit. Care Med. 16, 1384-1388.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.16 , pp. 1384-1388
    • Geiser, T.1    Atabai, K.2    Jarreau, P.H.3    Ware, L.B.4    Pugin, J.5    Matthay, M.A.6
  • 15
    • 33750439801 scopus 로고    scopus 로고
    • Simulating properties of in vitro epithelial cell morphogenesis
    • doi:10.1371/journal.pcbi.0020129
    • Grant, M. R., Mostov, K. E., Tlsty, T. D. & Hunt, C. A. 2006 Simulating properties of in vitro epithelial cell morphogenesis. PLoS Comput. Biol. 2, e129. (doi:10.1371/journal.pcbi.0020129)
    • (2006) PLoS Comput. Biol. , vol.2
    • Grant, M.R.1    Mostov, K.E.2    Tlsty, T.D.3    Hunt, C.A.4
  • 17
    • 38149052910 scopus 로고    scopus 로고
    • The epithelium in acute lung injury/acute respiratory distress syndrome
    • doi:10.1097/MCC.0b013e3282f417a0
    • Gropper, M. A. & Wiener-Kronish, J. 2008 The epithelium in acute lung injury/acute respiratory distress syndrome. Curr. Opin. Crit. Care 14, 11-15. (doi:10.1097/MCC.0b013e3282f417a0)
    • (2008) Curr. Opin. Crit. Care , vol.14 , pp. 11-15
    • Gropper, M.A.1    Wiener-Kronish, J.2
  • 18
    • 33646182163 scopus 로고    scopus 로고
    • Deterministic model of dermal wound invasion incorporating receptor-mediated signal transduction and spatial gradient sensing
    • doi:10.1529/biophysj.105.077610
    • Haugh, J. M. 2006 Deterministic model of dermal wound invasion incorporating receptor-mediated signal transduction and spatial gradient sensing. Biophys. J. 90, 2297-2308. (doi:10.1529/biophysj.105.077610)
    • (2006) Biophys. J. , vol.90 , pp. 2297-2308
    • Haugh, J.M.1
  • 21
    • 0028556511 scopus 로고
    • Transforming growth factor-a enhances alveolar epithelial cell repair in a new in vitro model
    • Kheradmand, F., Folkesson, H. G., Shum, L., Derynk, R., Pytela, R. & Matthay, M. A. 1994 Transforming growth factor-a enhances alveolar epithelial cell repair in a new in vitro model. Am. J. Physiol. 267, L728-L738.
    • (1994) Am. J. Physiol. , vol.267
    • Kheradmand, F.1    Folkesson, H.G.2    Shum, L.3    Derynk, R.4    Pytela, R.5    Matthay, M.A.6
  • 22
    • 62849107322 scopus 로고    scopus 로고
    • A computational approach to understand in vitro alveolar morphogenesis
    • doi:10.1371/journal.pone.0004819
    • Kim, S. H., Yu, W., Mostov, K., Matthay, M. A. & Hunt, C. A. 2009 A computational approach to understand in vitro alveolar morphogenesis. PLoS ONE 4, e4819. (doi:10.1371/journal.pone.0004819)
    • (2009) PLoS ONE , vol.4
    • Kim, S.H.1    Yu, W.2    Mostov, K.3    Matthay, M.A.4    Hunt, C.A.5
  • 23
    • 0033994703 scopus 로고    scopus 로고
    • Novel method for the quantitative assessment of cell migration: A study on the motility of rabbit anterior cruciate (ACL) and medial collateral ligament (MCL) cells
    • DOI 10.1089/107632700320865
    • Kobayashi, K., Healey, R. M., Sah, R. L., Clark, J. J., Tu, B. P., Goomer, R. S., Akeson, W. H., Moriya, H. & Amiel, D. 2000 Novel method for the quantitative assessment of cell migration: a study on the motility of rabbit anterior cruciate (ACL) and medial collateral ligament (MCL) cells. Tissue Eng. 6, 29-38. (doi:10.1089/107632700320865) (Pubitemid 30123980)
    • (2000) Tissue Engineering , vol.6 , Issue.1 , pp. 29-38
    • Kobayashi, K.1    Healey, R.M.2    Sah, R.L.3    Clark, J.J.4    Tu, B.P.5    Goomer, R.S.6    Akeson, W.H.7    Moriya, H.8    Amiel, D.9
  • 25
    • 0029984280 scopus 로고
    • Lung alveolar epithelial cell migration in vitro: Modulator and regulation processes
    • Lesur, O., Arsalane, K. & Lane, D. 1995 Lung alveolar epithelial cell migration in vitro: modulator and regulation processes. Am. J. Physiol. 270, L311-L319.
    • (1995) Am. J. Physiol. , vol.270
    • Lesur, O.1    Arsalane, K.2    Lane, D.3
  • 26
    • 50949091234 scopus 로고    scopus 로고
    • A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury
    • doi:10.1371/journal.pone.0002789
    • Li, N. Y., Verdolini, K., Clermont, G., Mi, Q., Rubinstein, E. N., Hebda, P. A. & Vodovotz, Y. 2008 A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury. PLoS ONE 3, e2789. (doi:10.1371/journal.pone.0002789)
    • (2008) PLoS ONE , vol.3
    • Li, N.Y.1    Verdolini, K.2    Clermont, G.3    Mi, Q.4    Rubinstein, E.N.5    Hebda, P.A.6    Vodovotz, Y.7
  • 27
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • doi:10.1038/nprot.2007.30
    • Liang, C. C., Park, A. Y. & Guan, J. L. 2007 In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat. Protocols 2, 329-333. (doi:10.1038/nprot.2007.30)
    • (2007) Nat. Protocols , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 28
    • 26844529359 scopus 로고    scopus 로고
    • 2005MASON: A multiagent simulation environment
    • doi:10.1177/0037549705058073
    • Luke, S., Cioffi-Revilla, C., Panait, L., Sullivan, K. & Balan, G. 2005MASON: a multiagent simulation environment. SIMULATION 81, 517-527. (doi:10.1177/0037549705058073)
    • SIMULATION , vol.81 , pp. 517-527
    • Luke, S.1    Cioffi-Revilla, C.2    Panait, L.3    Sullivan, K.4    Balan, G.5
  • 29
    • 2342646187 scopus 로고    scopus 로고
    • Traveling wave model to interpret a wound-healing cell migration assay for human peritoneal mesothelial cells
    • doi:10.1089/107632704323061834
    • Maini, P. K., McElwain, D. L. & Leavesley, D. I. 2004 Traveling wave model to interpret a wound-healing cell migration assay for human peritoneal mesothelial cells. Tissue Eng. 10, 475-482. (doi:10.1089/107632704323061834)
    • (2004) Tissue Eng. , vol.10 , pp. 475-482
    • Maini, P.K.1    McElwain, D.L.2    Leavesley, D.I.3
  • 30
    • 26244446442 scopus 로고    scopus 로고
    • Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management
    • doi:10.1165/rcmb.F305
    • Matthay, M. A. & Zimmerman, G. A. 2005 Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am. J. Respir. Cell Mol. Biol. 33, 319-327. (doi:10.1165/rcmb.F305)
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.33 , pp. 319-327
    • Matthay, M.A.1    Zimmerman, G.A.2
  • 31
    • 34848830242 scopus 로고    scopus 로고
    • Agent-based model of inflammation and wound healing: Insights into diabetic foot ulcer pathology and the role of transforming growth factor- b1
    • doi:10.1111/j.1524-475X.2007.00271.x
    • Mi, Q., Rivière, B., Clermont, G., Steed, D. L. & Vodovotz, Y. 2007 Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor- b1. Wound Repair Regen. 15, 671-682. (doi:10.1111/j.1524-475X.2007.00271.x)
    • (2007) Wound Repair Regen. , vol.15 , pp. 671-682
    • Mi, Q.1    Rivière, B.2    Clermont, G.3    Steed, D.L.4    Vodovotz, Y.5
  • 32
    • 0025825990 scopus 로고
    • Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors
    • Montesano, R., Schaller, G. & Orci, L. 1991 Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell 66, 697-711. (doi:10.1016/0092-8674(91)90115-F) (Pubitemid 121001705)
    • (1991) Cell , vol.66 , Issue.4 , pp. 697-711
    • Montesano, R.1    Schaller, G.2    Orci, L.3
  • 34
    • 33745714440 scopus 로고    scopus 로고
    • Role of boundary conditions in an experimental model of epithelial wound healing
    • doi:10.1152/ajpcell.00411.2005
    • Nikolić, D. L., Boettiger, A. N., Bar-Sagi, D., Carbeck, J. D. & Shvartsman, S. Y. 2006 Role of boundary conditions in an experimental model of epithelial wound healing. Am. J. Physiol. Cell Physiol. 291, 68-75. (doi:10.1152/ajpcell.00411.2005)
    • (2006) Am. J. Physiol. Cell Physiol. , vol.291 , pp. 68-75
    • Nikolić, D.L.1    Boettiger, A.N.2    Bar-Sagi, D.3    Carbeck, J.D.4    Shvartsman, S.Y.5
  • 35
    • 0036636095 scopus 로고    scopus 로고
    • Building epithelial architecture: Insights from three-dimensional culture models
    • doi:10.1038/nrm859
    • O'Brien, L. E., Zegers, M. M. & Mostov, K. E. 2002 Building epithelial architecture: insights from three-dimensional culture models. Nat. Rev. Mol. Cell Biol. 3, 531-537. (doi:10.1038/nrm859)
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 531-537
    • O'Brien, L.E.1    Zegers, M.M.2    Mostov, K.E.3
  • 37
    • 0001087921 scopus 로고    scopus 로고
    • Simple modelling of extracellular matrix alignment in dermal wound healing I. Cell flux induced alignment
    • doi:10.1080/ 10273669808833018
    • Olsen, L., Maini, P. K., Sherratt, J. A. & Marchant, B. 1998 Simple modelling of extracellular matrix alignment in dermal wound healing I. Cell flux induced alignment. Comput. Math. Methods Med. 1, 175-192. (doi:10.1080/ 10273669808833018)
    • (1998) Comput. Math. Methods Med. , vol.1 , pp. 175-192
    • Olsen, L.1    Maini, P.K.2    Sherratt, J.A.3    Marchant, B.4
  • 38
    • 0942287705 scopus 로고    scopus 로고
    • Mathematical modeling of airway epithelial wound closure during cyclic mechanical strain
    • doi:10. 1152/japplphysiol.00510.2003
    • Savla, U., Olson, L. E. & Waters, C. M. 2004 Mathematical modeling of airway epithelial wound closure during cyclic mechanical strain. J. Appl. Physiol. 96, 566-574. (doi:10. 1152/japplphysiol.00510.2003)
    • (2004) J. Appl. Physiol. , vol.96 , pp. 566-574
    • Savla, U.1    Olson, L.E.2    Waters, C.M.3
  • 39
    • 0030268157 scopus 로고    scopus 로고
    • Mechanisms of corneal epithelial wound healing
    • doi:10.1016/0009-2509(96)00299-0
    • Sheardown, H. & Cheng, Y. L. 1996 Mechanisms of corneal epithelial wound healing. Chem. Eng. Sci. 51, 4517-4529. (doi:10.1016/0009-2509(96)00299-0)
    • (1996) Chem. Eng. Sci. , vol.51 , pp. 4517-4529
    • Sheardown, H.1    Cheng, Y.L.2
  • 40
    • 0036332895 scopus 로고    scopus 로고
    • Theoretical models of wound healing: Past successes and future challenges
    • doi:10.1016/S1631-0691(02)01464-6
    • Sherratt, J. A. & Dallon, J. C. 2002 Theoretical models of wound healing: past successes and future challenges. C R Biol. 325, 557-564. (doi:10.1016/S1631-0691(02)01464-6)
    • (2002) C R Biol. , vol.325 , pp. 557-564
    • Sherratt, J.A.1    Dallon, J.C.2
  • 42
    • 33750443228 scopus 로고    scopus 로고
    • Looking inside an invasion wave of cells using continuum models: Proliferation is the key
    • doi:10.1016/j.jtbi.2006.06.021
    • Simpson, M. J., Landman, K. A., Hughes, B. D. & Newgreen, D. F. 2006 Looking inside an invasion wave of cells using continuum models: proliferation is the key. J. Theor. Biol. 243, 343-360. (doi:10.1016/j.jtbi.2006.06.021)
    • (2006) J. Theor. Biol. , vol.243 , pp. 343-360
    • Simpson, M.J.1    Landman, K.A.2    Hughes, B.D.3    Newgreen, D.F.4
  • 43
    • 57649238065 scopus 로고    scopus 로고
    • Cell migration and proliferation during monolayer formation and wound healing
    • doi:10.1016/j.ces.2008.10.008
    • Tremel, A., Cai, A., Tirtaatmadja, N., Hughes, B. D., Stevens, G. W., Landman, K. A. & O'Connor, A. J. 2009 Cell migration and proliferation during monolayer formation and wound healing. Chem. Eng. Sci. 64, 247-253. (doi:10.1016/j.ces.2008.10.008)
    • (2009) Chem. Eng. Sci. , vol.64 , pp. 247-253
    • Tremel, A.1    Cai, A.2    Tirtaatmadja, N.3    Hughes, B.D.4    Stevens, G.W.5    Landman, K.A.6    O'Connor, A.J.7
  • 44
    • 26044474453 scopus 로고    scopus 로고
    • Fugetaxis: Active movement of leukocytes away from a chemokinetic agent
    • doi:10.1007/s00109-005-0675-z
    • Vianello, F., Olszak, I. T. & Poznansky, M. C. 2005 Fugetaxis: active movement of leukocytes away from a chemokinetic agent. J. Mol. Med. 83, 752-763. (doi:10.1007/s00109-005-0675-z)
    • (2005) J. Mol. Med. , vol.83 , pp. 752-763
    • Vianello, F.1    Olszak, I.T.2    Poznansky, M.C.3
  • 45
    • 4544247005 scopus 로고    scopus 로고
    • Agent-based computational modeling of wounded epithelial cell monolayers
    • doi:10.1109/TNB.2004.833680
    • Walker, D. C., Hill, G., Wood, S. M., Smallwood, R. H. & Southgate, J. 2004 Agent-based computational modeling of wounded epithelial cell monolayers. IEEE Trans. Nanobiosci. 3, 153-163. (doi:10.1109/TNB.2004.833680)
    • (2004) IEEE Trans. Nanobiosci. , vol.3 , pp. 153-163
    • Walker, D.C.1    Hill, G.2    Wood, S.M.3    Smallwood, R.H.4    Southgate, J.5
  • 46
    • 1342270006 scopus 로고    scopus 로고
    • The molecular genetics of lung morphogenesis and injury repair
    • doi:10.1016/S1526-0542(04)90052-8
    • Warburton, D. & Bellusci, S. 2004 The molecular genetics of lung morphogenesis and injury repair. Pediatr. Respir. Rev. 5, S283-S287. (doi:10.1016/S1526-0542(04)90052-8)
    • (2004) Pediatr. Respir. Rev. , vol.5
    • Warburton, D.1    Bellusci, S.2
  • 48
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • doi:10.1056/NEJM200005043421806
    • Ware, L. B. & Matthay, M. A. 2000 The acute respiratory distress syndrome. N. Engl. J. Med. 342, 1334-1349. (doi:10.1056/NEJM200005043421806)
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 49
    • 0036080893 scopus 로고    scopus 로고
    • Keratinocyte and hepatocyte growth factors in the lung: Roles in lung development, inflammation, and repair
    • Ware, L. B. & Matthay, M. A. 2002 Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am. J. Physiol. Lung Cell Mol. Physiol. 282, L924-L940.
    • (2002) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.282
    • Ware, L.B.1    Matthay, M.A.2
  • 50
    • 34248223108 scopus 로고    scopus 로고
    • Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis
    • doi:10.1091/mbc.E06-11-1052
    • Yu, W., Fang, X., Ewald, A., Wong, K., Hunt, C. A.,Werb, Z., Matthay, M. A. & Mostov, K. 2007 Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol. Biol. Cell 18, 1693-1700. (doi:10.1091/mbc.E06-11-1052)
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1693-1700
    • Yu, W.1    Fang, X.2    Ewald, A.3    Wong, K.4    Hunt, C.A.5    Werb, Z.6    Matthay, M.A.7    Mostov, K.8


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