Role of boundary conditions in an experimental model of epithelial wound healing

American Journal of Physiology - Cell Physiology

Volumn 291, Issue 1, 2006, Pages

  Nikolić, Djordje L ^a   Boettiger, Alistair N ^b   Bar Sagi, Dafna ^c   Carbeck, Jeffrey D ^a   Shvartsman, Stanislav Y ^a,b  

^a Princeton University   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Cell communication; Coordinated cell sheet migration; ERK; Multicellular dynamics; Reactive oxygen species; Surface patterning

Indexed keywords

DIMETICONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE;

ANIMAL MODEL; ARTICLE; CELL MIGRATION; CELL MOTION; COW; ENZYME ACTIVATION; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; TISSUE CULTURE; WOUND HEALING;

ANIMALS; CELL LINE; CELL MOVEMENT; DOGS; EPITHELIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; STRESS, MECHANICAL; WOUND HEALING;

EID: 33745714440     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00411.2005     Document Type: Article

References (31)

1. Altan ZM and Fenteany G. c-Jun N-terminal kinase regulates lamellipodial protrusion and cell sheet migration during epithelial wound closure by a gene expression-independent mechanism. Biochem Biophys Res Commun 322: 56-67, 2004.
2. Block ER, Matela AR, SundarRaj N, Iszkula ER, and Klarlund JK. Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints. Role of heparin-binding epidermal growth factor-like growth factor signaling. J Biol Chem 279: 24307-24312, 2004.
3. Brodu V, Elstob PR, and Gould AP. EGF receptor signaling regulates pulses of cell delamination from the Drosophila ectoderm. Devel Cell 7: 885-895, 2004.
4. Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu BE, Wright A, Vanderbilt C, and Cobb MH. MAP kinases. Chem Rev 101: 2449-2476, 2001.
5. Chung E, Graves-Deal R, Franklin JL, and Coffey RJ. Differential effects of amphiregulin and TGF-α on the morphology of MDCK cells. Exp Cell Res 309: 149-160, 2005.
6. Dallon JC and Othmer HG. How cellular movement determines the collective force generated by the Dictyostelium discoideum slug. J Theor Biol 231: 203-222, 2004.
7. Dimilla PA, Barbee K, and Lauffenburger DA. Mathematical model for the effects of adhesion and mechanics on cell-migration speed. Biophys J 60: 15-37, 1991.
8. Du Roure O, Saez A, Buguin A, Austin RH, Chavrier P, Siberzan P, and Ladoux B. Force mapping in epithelial cell migration. Proc Natl Acad Sci USA 102: 2390-2395, 2005.
9. Galko MJ and Krasnow MA. Cellular and genetic analysis of wound healing in Drosophila larvae. Plos Biol 2: 1114-1126, 2004.
10. Gracheva ME and Othmer HG. A continuum model of motility in ameboid cells. Bull Math Biol 66: 167-193, 2004.
11. Gregg D, Rauscher FM, and Goldschmidt-Clermont PJ. Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch. Am J Physiol Cell Physiol 285: C723-C734, 2003.
12. Kane RS, Takayama S, Ostuni E, Ingber DE, and Whitesides GM. Patterning proteins and cells using soft lithography. Biomaterials 20: 2363-2376, 1999.
13. i dynamics in the rabbit corneal epithelium. Arch Histol Cytol 62: 129-138, 1999.
14. Klepeis VE, Weinger I, Kaczmarek E, and Trinkaus-Randal V. P2Y receptors play a critical role in epithelial cell communication and migration. J Cell Biochem 93: 1115-1133, 2004.
15. Lauffenburger DA and Horwitz AF. Cell migration: a physically integrated molecular process. Cell 84: 359-369, 1996.
16. Martin P and Parkhurst SM. Parallels between tissue repair and embryo morphogenesis. Development 131: 3021-3034, 2004.
17. Martinez-Arias A and Stewart A. Molecular Principles of Animal Development. New York: Oxford University Press, 2002.
18. Matsubayashi Y, Ebisuya M, Honjoh S, and Nishida E. ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing. Curr Biol 14: 731-735, 2004.
19. Mine N, Iwamoto R, and Mekada E. HB-EGF promotes epithelial cell migration in eyelid development. Development 132: 4317-4326, 2005.
20. Nimnual AS, Taylor LJ, and Bar-Sagi D. Redox-dependent downregulation of Rho by Rac. Nat Cell Biol 159: 361-370, 2003.
21. Ostuni E, Kane R, Chen CS, Ingber DE, and Whitesides GM. Patterning mammalian cells using elastomeric membranes. Langmuir 16: 7811-7819, 2000.
22. Pribyl M, Muratov CB, and Shavartsman SY. Long-range signal transmission in autocrine relays. Biophys J 84: 883-896, 2003.
23. Pribyl M, Muratov CB, and Shvartsman SY. Discrete models of autocrine cell communication in epithelial layers. Biophys J 84: 3624-3635, 2003.
24. Storz P. Reactive oxygen species in tumor progression. Front Biosci 10: 1881-1896, 2005.
25. Taniyama Y and Griendling KK. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42: 1075-1081, 2003.
26. Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8: D369-D391, 2003.
27. Wasserman L. All of Statistics: A Concise Course in Statistical Inference. New York: Springer, 2003.
28. Wu RF, Xu YC, Ma Z, Nwariaku FEA, Sarosi GA, and Terada LS. Subcellular targeting of oxidants during endothelial cell migration. J Cell Biol 171: 893-904, 2005.
29. Xia Y and Kao WW. The signaling pathways in tissue morphogenesis: a lesson from mice with eye-open at birth phenotype. Biochem Pharmacol 68: 997-1001, 2004.
30. Xu KP, Ding Y, Ling J, Dong Z, and Yu FS. Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells. Invest Ophthalmol Vis Sci 45: 813-820, 2004.
31. Zhang Z, Oliver P, Lancaster SR, Schwarzenberger PO, Joshi MS, Cork J, and Kolls JK. Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate. FASEB J 15: 303-305, 2001.