β-Ionone-induced apoptosis in human osteosarcoma (U2os) cells occurs via a p53-dependent signaling pathway

Molecular Biology Reports

Volumn 37, Issue 6, 2010, Pages 2653-2663

  Zhu, Jiang ^a   Zhang, Lei ^b   Jin, Xiaoming ^b   Han, Xinying ^b   Sun, Chuanhui ^b   Yan, Jinglong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Ionone; Apoptosis; p53 Dependent mitochondrial pathway; U2os

Indexed keywords

BETA IONONE; CASPASE 3; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; BETA-IONONE; NORISOPRENOID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME RELEASE; FRUIT; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INHIBITION KINETICS; MITOCHONDRION; NICK END LABELING; OSTEOSARCOMA; OSTEOSARCOMA CELL; SIGNAL TRANSDUCTION; TIME; UPREGULATION; VEGETABLE; CELL SURVIVAL; DNA FRAGMENTATION; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE; ULTRASTRUCTURE; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MITOCHONDRIA; NORISOPRENOIDS; OSTEOSARCOMA; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77955609175     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9793-y     Document Type: Article

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