Combination of the 2A/furin technology with an animal component free cell line development platform process

Applied Microbiology and Biotechnology

Volumn 87, Issue 4, 2010, Pages 1517-1524

  Jostock, Thomas ^a   Dragic, Zorica ^a   Fang, Jianmin ^b   Jooss, Karin ^b   Wilms, Burkhard ^a   Knopf, Hans Peter ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b CELL GENESYS INC   (United States)

Author keywords

2A furin; Cell culture; CHO; Recombinant antibody production

Indexed keywords

CHO CELL; DEVELOPMENT PLATFORM; DEVELOPMENT PROCESS; EVALUATION STUDY; EXPRESSION CASSETTE; EXPRESSION SYSTEM; FED BATCHES; FREE CELLS; NOVARTIS; OPEN READING FRAME; PRODUCT QUALITY; RECOMBINANT ANTIBODY PRODUCTION; REFERENCE CONTROL; SDS-PAGE; SHAKE FLASKS; VECTOR SYSTEMS;

ANIMAL CELL CULTURE; ANTIBODIES; CLONING; CONTROL; NUCLEIC ACIDS; QUALITY CONTROL; TECHNOLOGY; VECTORS;

CELL CULTURE;

FURIN;

ANTIBODY; BIOREACTOR; BIOTECHNOLOGY; CLONE; GENE EXPRESSION; RECOMBINATION;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL CLONING; CELL SELECTION; CHO CELL; GENETIC TRANSFECTION; IMMUNOASSAY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; ANIMAL; BIOTECHNOLOGY; CHO CELL LINE; CRICETULUS; EVALUATION STUDY; GENE EXPRESSION; GENE VECTOR; GENETICS; HAMSTER; METABOLISM; PROCEDURES;

ANIMALS; BIOTECHNOLOGY; CHO CELLS; CRICETINAE; CRICETULUS; FURIN; GENE EXPRESSION; GENETIC VECTORS;

ANIMALIA;

EID: 77955559895     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2625-0     Document Type: Article

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