Modeling assembly, aggregation, and chaperoning of immunoglobulin G production in insect cells

Biotechnology and Bioengineering

Volumn 56, Issue 1, 1997, Pages 106-116

  Whiteley, Erik M ^a   Hsu, Tsu An ^a,b   Betenbaugh, Michael J ^a  

^a Johns Hopkins University   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Aggregation; Baculovirus insect cells; BiP; Chaperones; Immunoglobulin; Mathematical model

Indexed keywords

ADENOSINETRIPHOSPHATE; AGGLOMERATION; ANIMAL CELL CULTURE; BIOSYNTHESIS; COMPUTER SIMULATION; DISSOCIATION; MATHEMATICAL MODELS; OLIGOMERS; POLYPEPTIDES; VIRUSES;

BACULOVIRUS INSECT CELLS; BINDING PROTEIN (BIP); IMMUNOGLOBULIN;

ANTIBODIES;

CHAPERONE; IMMUNOGLOBULIN G;

ANIMAL CELL; ARTICLE; BACULOVIRUS; CHEMICAL REACTION KINETICS; IMMUNOGLOBULIN PRODUCING CELL; INSECT; MOLECULAR MODEL; NONHUMAN; PREDICTION; PROTEIN ASSEMBLY; PROTEIN SYNTHESIS;

EID: 0031555002     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19971005)56:1<106::AID-BIT12>3.0.CO;2-I     Document Type: Article

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