γ-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions

Bioorganic Chemistry

Volumn 38, Issue 5, 2010, Pages 196-201

  Pensato, Soccorsa ^a   Saviano, Michele ^a   Bianchi, Nicoletta ^b   Borgatti, Monica ^b   Fabbri, Enrica ^b   Gambari, Roberto ^b   Romanelli, Alessandra ^a,c  

^a CNR   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Biological activity; EMSA; PNA; Solid phase synthesis

Indexed keywords

DOUBLE STRANDED DNA; GAMMA HYDROXYMETHYL PEPTIDE NUCLEIC ACID; MESSENGER RNA; MONOMER; PEPTIDE NUCLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DNA BINDING; DNA TRANSCRIPTION; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; NUCLEIC ACID SYNTHESIS; PRIORITY JOURNAL; PROTEIN DNA INTERACTION;

CIRCULAR DICHROISM; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; PEPTIDE NUCLEIC ACIDS; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 77955554466     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2010.06.002     Document Type: Article

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