Cutaneous lupus in infancy and childhood

Lupus

Volumn 19, Issue 9, 2010, Pages 1112-1117

  Lee, L A ^a,b  

^a DENVER HEALTH MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

anti Ro antibodies; childhood; cutaneous lupus erythematosus; infancy; neonatal lupus erythematosus; pediatric lupus erythematosus

Indexed keywords

AUTOANTIBODY; CORTICOSTEROID; HYDROXYCHLOROQUINE; MATERNAL ANTIBODY;

AUTOIMMUNITY; CHILDHOOD DISEASE; CLINICAL FEATURE; HUMAN; INFANT DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SKIN LUPUS ERYTHEMATOSUS; TREATMENT INDICATION; TREATMENT OUTCOME;

AGE FACTORS; ANIMALS; AUTOANTIBODIES; AUTOIMMUNITY; CHILD; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LUPUS ERYTHEMATOSUS, CUTANEOUS; PREGNANCY;

EID: 77955530176     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203310370347     Document Type: Review

References (58)

1. Franco HL, Weston WL, Peebles C., Forstot SL, Phanuphak P. Autoantibodies directed against sicca syndrome antigens in the neonatal lupus syndrome. J Am Acad Dermatol 1981 ; 4: 67-72.
2. Lee LA Neonatal lupus erythematosus. J Invest Dermatol 1993 ; 100: 9S - 13S.
3. Lee LA Neonatal lupus: clinical features, therapy, and pathogenesis. Curr Rheumatol Rep 2001 ; 3: 391-395.
4. Lee LA, Weston WL Special considerations concerning the cutaneous manifestations of rheumatic diseases in children. In: Sontheimer RD, Provost TT (eds), Cutaneous manifestations of rheumatic diseases. Baltimore, MD: Williams & Wilkins; 1996. p. 323-344.
5. Buyon JP, Hiebert R., Copel J., et al. Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol 1998 ; 31: 1658-1666.
6. Neiman AR, Lee LA, Weston WL, Buyon JP Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry. J Pediatr 2000 ; 137: 674-680.
7. Harmon CE, Lee LA, Huff JC, Norris DA, Weston WL The frequency of antibodies to the SSA/Ro antigen in pregnancy sera. Arthritis Rheum 1984 ; 28: S20 (abstract).
8. Weston WL, Morelli JG, Lee LA The clinical spectrum of anti-Ropositive cutaneous neonatal lupus erythematosus. J Am Acad Dermatol 1999 ; 40: 675-681.
9. Thornton CM, Eichenfield LF, Shinall EA, et al. Cutaneous telangiectases in neonatal lupus erythematosus. J Am Acad Dermatol 1995 ; 33: 19-25.
10. Satter EK, High WA Non-bullous neutrophilic dermatosis within neonatal lupus erythematosus. J Cutan Pathol 2007 ; 34: 958-960.
11. David-Bajar KM, Bennion SD, DeSpain JD, Golitz LE, Lee LA Clinical, histologic, and immunofluorescent distinctions between subacute cutaneous lupus erythematosus and discoid lupus erythematosus. J Invest Dermatol 1992 ; 99: 251-257.
12. Lee LA, Gaither KK, Coulter SN, Norris DA, Harley JB Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice. J Clin Invest 1989 ; 83: 1556-1562.
13. Taylor-Albert E., Reichlin M., Toews WH, Overholt ED, Lee LA Delayed dilated cardiomyopathy as a manifestation of neonatal lupus: case reports, autoantibody analysis, and management. Pediatrics 1997 ; 99: 733-735.
14. Lee LA, Sokol RJ, Buyon JP Hepatobiliary disease in neonatal lupus: prevalence and clinical characteristics in cases enrolled in a national registry. Pediatrics 2002 ; 109: E11.
15. Watson R., Kang JE, May M., Hudak M., Kickler T., Provost TT Thrombocytopenia in the neonatal lupus syndrome. Arch Dermatol 1988 ; 124: 560-563.
16. Prendiville JS, Cabral DA, Poskitt KJ, Au S., Sargent MA Central nervous system involvement in neonatal lupus erythematosus. Pediatr Dermatol 2003 ; 20: 60-67.
17. Boros CA, Spence D., Blaser S., Silverman ED Hydrocephalus and macrocephaly: new manifestations of neonatal lupus erythematosus. Arthritis Rheum 2007 ; 57: 261-266.
18. Martin V., Lee LA, Askanase AD, Katholi M., Buyon JP Long-term followup of children with neonatal lupus and their unaffected siblings. Arthritis Rheum 2002 ; 46: 2377-2383.
19. McCune AB, Weston WL, Lee LA Maternal and fetal outcome in neonatal lupus erythematosus. Ann Intern Med 1987 ; 106: 518-523.
20. Julkunen H., Kurki P., Kaaja R., et al. Isolated congenital heart block. Long-term outcome of mothers and characterization of the immune response to SS-A/Ro and to SS-B/La. Arthritis Rheum 1993 ; 36: 1588-1598.
21. Alexander E., Buyon JP, Provost TT, Guarnieri T. Anti-Ro/SS-A antibodies in the pathophysiology of congenital heart block in neonatal lupus syndrome, an experimental model. In vitro electrophysiologic and immunocytochemical studies. Arthritis Rheum 1992 ; 35: 176-189.
22. Garcia S., Nascimento JHM, Bonfa E., et al. Cellular mechanism of the conduction abnormalities induced by serum from anti-Ro/SSA-positive patients in rabbit hearts. J Clin Invest 1994 ; 93: 718-724.
23. Viana VST, Garcia S., Nascimento JHM, et al. Affinity purified anti-52 kD Ro/SSA antibody induces A-V heart block in vitro. Arthritis Rheum 1995 ; 38: S306 (abstract).
24. Miranda-Carus ME, Boutjdir M., Tseng CE, DiDonato F., Chan EK, Buyon JP Induction of antibodies reactive with SSA/Ro-SSB/ La and development of congenital heart block in a murine model. J Immunol 1998 ; 161: 5886-5892.
25. Mazel JA, El-Sherif N., Buyon J., Boutjdir M. Electrocardiographic abnormalities in a murine model injected with IgG from mothers of children with congenital heart block. Circulation 1999 ; 99: 1914-1918.
26. Suzuki H., Silverman ED, Wu X., et al. Effect of maternal autoantibodies on fetal cardiac conduction: an experimental murine model. Pediatr Res 2005 ; 57: 557-562.
27. Miranda-Carus ME, Askanase AD, Clancy RM, et al. Anti-SSA/ Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages. J Immunol 2000 ; 165: 5345-5351.
28. Clancy RM, Askanase AD, Kapur RP, et al. Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block. J Immunol 2002 ; 169: 2156-2163.
29. Xue D., Shi H., Smith JD, et al. A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen. Proc Natl Acad Sci U S A 2003 ; 100: 7503-7508.
30. Provost TT, Watson R., Gammon WR, Radowsky M., Harley JB, Reichlin M. The neonatal lupus syndrome associated with U1RNP (nRNP) antibodies. N Engl J Med 1987 ; 316: 1135-1138.
31. Sontheimer RD, Nguyen TQ, Buyon JP, et al. Clinical correlations of autoantibodies to a recombinant, hYRNA-binding form of human calreticulin. J Invest Dermatol 1996 ; 106: 938 (abstract).
32. Maddison PJ, Lee L., Reichlin M., et al. Anti-p57: a novel association with neonatal lupus. Clin Exp Immunol 1995 ; 99: 42-48.
33. Wang D., Buyon JP, Zhu W., Chan EK Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies. J Clin Invest 1999 ; 104: 1265-1275.
34. Miyagawa S., Yanagi K., Yoshioka A., Kidoguchi K., Shirai T., Hayashi Y. Neonatal lupus erythematosus: maternal IgG antibodies bind to a recombinant NH2-terminal fusion protein encoded by human alpha-fodrin cDNA. J Invest Dermatol 1998 ; 111: 1189-1192.
35. Borda E., Sterin-Borda L. Autoantibodies against neonatal heart M1 muscarinic acetylcholine receptor in children with congenital heart block. J Autoimmun 2001 ; 16: 143-150.
36. Eftekhari P., Roegel JC, Lezoualch F., Fischmeister R., Imbs JL, Hoebeke J. Induction of neonatal lupus in pups of mice immunized with synthetic peptides derived from amino acid sequences of the serotoninergic 5-HT4 receptor. Eur J Immunol 2001 ; 31: 573-579.
37. Buyon JP, Tseng CE, Di Donato F., Rashbaum W., Morris A., Chan EK Cardiac expression of 52beta, an alternative transcript of the congenital heart block-associated 52-kd SS-A/Ro autoantigen, is maximal during fetal development. Arthritis Rheum 1997 ; 40: 655-660.
38. Fraire-Velazquez S., Herrera-Esparza R., Villalobos-Hurtado R., Avalos-Diaz E. Ontogeny of Ro hYRNAs in human heart. Scand J Rheumatol 1999 ; 28: 100-105.
39. Clancy RM, Neufing PJ, Zheng P., et al. Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. J Clin Invest 2006 ; 116: 2413-2422.
40. Lee LA, Frank MB, McCubbin VR, Reichlin M. The autoantibodies of neonatal lupus erythematosus. J Invest Dermatol 1994 ; 102: 963-966.
41. Bennion SD, Ferris C., Lieu TS, Reimer CB, Lee LA IgG subclasses in the serum and skin in subacute cutaneous lupus erythematosus and neonatal lupus erythematosus. J Invest Dermatol 1990 ; 95: 643-646.
42. Lee LA, Alvarez K., Gross T., Harley JB The recognition of human 60-kDa Ro ribonucleoprotein particles by antibodies associated with cutaneous lupus and neonatal lupus. J Invest Dermatol 1996 ; 107: 225-228.
43. Clancy RM, Backer CB, Yin X., et al. Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis. Arthritis Rheum 2004 ; 50: 2598-2603.
44. Strandberg L., Winqvist O., Sonesson SE, et al. Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block. Clin Exp Immunol 2008 ; 154: 30-37.
45. Stea EA, Routsias JG, Clancy RM, Buyon JP, Moutsopoulos HM, Tzioufas AG Anti-La/SSB antiidiotypic antibodies in maternal serum: a marker of low risk for neonatal lupus in an offspring. Arthritis Rheum 2006 ; 54: 2228-2234.
46. Schaller J. Lupus in childhood. Clin Rheum Dis 1982 ; 8: 219-228.
47. Wananukul S., Watana D., Pongprasit P. Cutaneous manifestations of childhood systemic lupus erythematosus. Pediatr Dermatol 1998 ; 15: 342-346.
48. George PM, Tunnessen Jr WW Childhood discoid lupus erythematosus. Arch Dermatol 1993 ; 129: 613-617.
49. Kettler AH, Bean SF, Duffy JO, Gammon WR Systemic lupus erythematosus presenting as a bullous eruption in a child. Arch Dermatol 1988 ; 124: 1083-1087.
50. Kuhn A., Richter-Hintz D., Oslislo C., Ruzicka T., Megahed M., Lehmann P. Lupus erythematosus tumidus-a neglected subset of cutaneous Lupus erythematosus: report of 40 cases. Arch Dermatol 2000 ; 136: 1033-1041.
51. Provost TT, Arnett FC, Reichlin M. Homozygous C2 deficiency, lupus erythematosus and anti-Ro (SSA) antibodies. Arthritis Rheum 1983 ; 26: 1279-1282.
52. Siamopoulou MA, Stefanou D., Drosos AA Subacute cutaneous lupus-erythematosus in childhood. Clin Rheum 1989 ; 8: 533-537.
53. Taieb A., Hehunstre J-P., Goetz J., et al. Lupus erythematosus panniculitis with partial genetic deficiency of C2 and C4 in a child. Arch Dermatol 1986 ; 122: 576-582.
54. Meyer O., Hauptmann G., Tappeiner G., Ochs HD, Mascart-Lemone F. Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies. Clin Exp Immunol 1985 ; 62: 678-684.
55. Manzi S., Urbach AH, McCune AB, et al. Systemic lupus erythematosus in a boy with chronic granulomatous disease: Case report and review of the literature. Arthritis Rheum 1991 ; 34: 101-105.
56. Faurschou A., Wulf HC The relation between sun protection factor and amount of suncreen applied in vivo. Br J Dermatol 2007 ; 156: 716-719.
57. Rahman P., Gladman DD, Urowitz MB Smoking interferes with efficacy of antimalarial therapy in cutaneous lupus. J Rheumatol 1998 ; 25: 1716-1719.
58. Jewell ML, McCauliffe DP Patients with cutaneous lupus erythematosus who smoke are less responsive to antimalarial treatment. J Am Acad Dermatol 2000 ; 42: 983-987.