-
1
-
-
0025962236
-
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice
-
Ashani Y., Shapira S., Levy D., Wolfe A.D., Doctor B.P., Raveh L. Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice. Biochem. Pharmacol. 1991, 41:37-41.
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 37-41
-
-
Ashani, Y.1
Shapira, S.2
Levy, D.3
Wolfe, A.D.4
Doctor, B.P.5
Raveh, L.6
-
2
-
-
0026314698
-
Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates
-
Broomfield C.A., Maxwell D.M., Solana R.P., Castro C.A., Finger A.V., Lenz D.E. Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates. J. Pharmacol. Exp. Ther. 1991, 259:633-638.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 633-638
-
-
Broomfield, C.A.1
Maxwell, D.M.2
Solana, R.P.3
Castro, C.A.4
Finger, A.V.5
Lenz, D.E.6
-
3
-
-
28744458362
-
In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger
-
Cerasoli D.M., Griffiths E.M., Doctor B.P., Saxena A., Fedorko J.M., Greig N.H., Yu Q.S., Huang Y., Wilgus H., Karatzas C.N., Koplovitz I., Lenz D.E. In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger. Chem. Biol. Interact. 2005, 157:363-365.
-
(2005)
Chem. Biol. Interact.
, vol.157
, pp. 363-365
-
-
Cerasoli, D.M.1
Griffiths, E.M.2
Doctor, B.P.3
Saxena, A.4
Fedorko, J.M.5
Greig, N.H.6
Yu, Q.S.7
Huang, Y.8
Wilgus, H.9
Karatzas, C.N.10
Koplovitz, I.11
Lenz, D.E.12
-
4
-
-
77955515089
-
-
Society for Neuroscience, 337.19
-
Cerasoli D.M., Robison C.L., Nwaneri I.Y., Somsamayvong B., Karatzas C.N., Wilgus H., Huang Y., McDonough J.H., Lenz D.E., Lumley L.A. Pretreatment with pegylated Protexia protects against exposure to the nerve agents VX and soman. Abstracts 2005, vol. 31. Society for Neuroscience, 337.19.
-
(2005)
Pretreatment with pegylated Protexia protects against exposure to the nerve agents VX and soman. Abstracts
, vol.31
-
-
Cerasoli, D.M.1
Robison, C.L.2
Nwaneri, I.Y.3
Somsamayvong, B.4
Karatzas, C.N.5
Wilgus, H.6
Huang, Y.7
McDonough, J.H.8
Lenz, D.E.9
Lumley, L.A.10
-
5
-
-
0027244369
-
Cholinesterases as scavengers for organophosphorous compounds: protection of primate performance against soman toxicity
-
Doctor B.P., Blick D.W., Caranto G., Castro C.A., Gentry M.K., Larison R., Maxwell D.M., Murphy M.R., Schutz M., Waibel K., Wolfe A.D.A.D. Cholinesterases as scavengers for organophosphorous compounds: protection of primate performance against soman toxicity. Chem. Biol. Interact. 1993, 87:285-293.
-
(1993)
Chem. Biol. Interact.
, vol.87
, pp. 285-293
-
-
Doctor, B.P.1
Blick, D.W.2
Caranto, G.3
Castro, C.A.4
Gentry, M.K.5
Larison, R.6
Maxwell, D.M.7
Murphy, M.R.8
Schutz, M.9
Waibel, K.10
Wolfe, A.D.A.D.11
-
6
-
-
28744449011
-
Bioscavengers for the protection of humans against organophosphate toxicity
-
Doctor B.P., Saxena A. Bioscavengers for the protection of humans against organophosphate toxicity. Chem. Biol. Interact. 2005, 157-158:167-171.
-
(2005)
Chem. Biol. Interact.
, pp. 167-171
-
-
Doctor, B.P.1
Saxena, A.2
-
7
-
-
28744437282
-
Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys
-
Lenz D.E., Maxwell D.M., Koplovitz I., Clark C.R., Capacio B.R., Cerasoli D.M., Federko J.M., Luo C., Saxena A., Doctor B.P., Olson C. Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys. Chem. Biol. Interact. 2005, 157-158:205-210.
-
(2005)
Chem. Biol. Interact.
, pp. 205-210
-
-
Lenz, D.E.1
Maxwell, D.M.2
Koplovitz, I.3
Clark, C.R.4
Capacio, B.R.5
Cerasoli, D.M.6
Federko, J.M.7
Luo, C.8
Saxena, A.9
Doctor, B.P.10
Olson, C.11
-
8
-
-
50649101957
-
Nerve agent bioscavengers; progress in development of a new mode of protection against organophosphorus exposure
-
CRC Press, Boca Raton, J.A. Romano, B. Lukey, H. Salem (Eds.)
-
Lenz D.E., Broomfield C.A., Yeung D.T., Masson P., Maxwell D.M., Cerasoli D.M. Nerve agent bioscavengers; progress in development of a new mode of protection against organophosphorus exposure. Chemical Warfare Agents: Toxicity at Low Levels 2007, 175-202. CRC Press, Boca Raton. 2nd edition. J.A. Romano, B. Lukey, H. Salem (Eds.).
-
(2007)
Chemical Warfare Agents: Toxicity at Low Levels
, pp. 175-202
-
-
Lenz, D.E.1
Broomfield, C.A.2
Yeung, D.T.3
Masson, P.4
Maxwell, D.M.5
Cerasoli, D.M.6
-
9
-
-
0012540729
-
Cholinesterase and carboxylesterase as scavengers for organophosphorous agents
-
American Chemical Society, Washington, J. Massoulie, F. Bacou, E. Barnard, A. Chatonnet, B.P. Doctor, D.M. Quinn (Eds.)
-
Maxwell D.M., Wolfe A.D., Ashani Y., Doctor B.P. Cholinesterase and carboxylesterase as scavengers for organophosphorous agents. Cholinesterases: Structure, Function, Mechanism, Genetics and Cell Biology 1991, 206-209. American Chemical Society, Washington. J. Massoulie, F. Bacou, E. Barnard, A. Chatonnet, B.P. Doctor, D.M. Quinn (Eds.).
-
(1991)
Cholinesterases: Structure, Function, Mechanism, Genetics and Cell Biology
, pp. 206-209
-
-
Maxwell, D.M.1
Wolfe, A.D.2
Ashani, Y.3
Doctor, B.P.4
-
10
-
-
0027241301
-
Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity
-
Raveh L., Grunwald J., Marcus D., Papier Y., Cohen E., Ashani Y. Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity. Biochem. Pharmacol. 1993, 45:2465-2474.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 2465-2474
-
-
Raveh, L.1
Grunwald, J.2
Marcus, D.3
Papier, Y.4
Cohen, E.5
Ashani, Y.6
-
11
-
-
0031193319
-
The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase
-
Raveh L., Grauer E., Grunwald J., Cohen E., Ashani Y. The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase. Toxicol. Appl. Pharmacol. 1997, 145:43-53.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 43-53
-
-
Raveh, L.1
Grauer, E.2
Grunwald, J.3
Cohen, E.4
Ashani, Y.5
-
12
-
-
0023526043
-
Acetylcholinesterase prophylaxis against organophosphate toxicity
-
Wolfe A.D., Rush R.S., Doctor B.P., Koplovitz I., Jones D.D. Acetylcholinesterase prophylaxis against organophosphate toxicity. Fund. Appl. Toxicol. 1987, 9:266-270.
-
(1987)
Fund. Appl. Toxicol.
, vol.9
, pp. 266-270
-
-
Wolfe, A.D.1
Rush, R.S.2
Doctor, B.P.3
Koplovitz, I.4
Jones, D.D.5
-
13
-
-
0027053644
-
Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity
-
Wolfe A.D., Blick D.W., Murphy M.R., Miller S.A., Gentry M.K., Hartgraves S.L., Doctor B.P. Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity. Toxicol. Appl. Pharmacol. 1992, 117:189-193.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.117
, pp. 189-193
-
-
Wolfe, A.D.1
Blick, D.W.2
Murphy, M.R.3
Miller, S.A.4
Gentry, M.K.5
Hartgraves, S.L.6
Doctor, B.P.7
-
14
-
-
35348893697
-
Recombinant Human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning
-
Huang Y.-J., Huang Y., Baldassarre H., Wang B., Lazaris A., Leduc M., Bilodeau A.S., Bellemare A., Côté M., Herskovits P., Touati M., Turcotte C., Valeanu L., Lemee N., Wilgus H., Bégin I., Bhatia B., Rao K., Neveu N., Brochu E., Pierson J., Hockley D.K., Cerasoli D.M., Lenz D.E., Karatzas C.N., Langermann S. Recombinant Human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc. Natl. Acad. Sci. 2007, 104:13603-13608.
-
(2007)
Proc. Natl. Acad. Sci.
, vol.104
, pp. 13603-13608
-
-
Huang, Y.-J.1
Huang, Y.2
Baldassarre, H.3
Wang, B.4
Lazaris, A.5
Leduc, M.6
Bilodeau, A.S.7
Bellemare, A.8
Côté, M.9
Herskovits, P.10
Touati, M.11
Turcotte, C.12
Valeanu, L.13
Lemee, N.14
Wilgus, H.15
Bégin, I.16
Bhatia, B.17
Rao, K.18
Neveu, N.19
Brochu, E.20
Pierson, J.21
Hockley, D.K.22
Cerasoli, D.M.23
Lenz, D.E.24
Karatzas, C.N.25
Langermann, S.26
more..
-
15
-
-
44849117242
-
Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin
-
Huang Y.-J., Lundy P.M., Lazaris A., Huang Y., Baldassarre H., Wang B., Turcotte C., Côté M., Bellemare A., Bilodeau A.S., Brouillard S., Touati M., Herskovits P., Begin I., Neveu N., Brochu E., Pierson J., Hockley D.K., Cerasoli D.M., Lenz D.E., Wilgus H., Karatzas C.N., Langermann S. Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin. BMC Biotechnol. 2008, 8:50.
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 50
-
-
Huang, Y.-J.1
Lundy, P.M.2
Lazaris, A.3
Huang, Y.4
Baldassarre, H.5
Wang, B.6
Turcotte, C.7
Côté, M.8
Bellemare, A.9
Bilodeau, A.S.10
Brouillard, S.11
Touati, M.12
Herskovits, P.13
Begin, I.14
Neveu, N.15
Brochu, E.16
Pierson, J.17
Hockley, D.K.18
Cerasoli, D.M.19
Lenz, D.E.20
Wilgus, H.21
Karatzas, C.N.22
Langermann, S.23
more..
-
16
-
-
33644811612
-
A new and rapid colorimetric determination of acetylcholinesterase activity
-
Ellman G.L., Courtney K.D., Andres V., Featherstone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 1961, 7:88-95.
-
(1961)
Biochem. Pharmacol.
, vol.7
, pp. 88-95
-
-
Ellman, G.L.1
Courtney, K.D.2
Andres, V.3
Featherstone, R.M.4
-
17
-
-
70350221013
-
Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase
-
Barakat N.H., Zheng X., Gilley C.B., MacDonald M., Okolotowicz K., Cashman J.R., Vyas S., Beck J.M., Hadad C.M., Zhang J. Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase. Chem. Res. Toxicol. 2009, 22:1669-1679.
-
(2009)
Chem. Res. Toxicol.
, vol.22
, pp. 1669-1679
-
-
Barakat, N.H.1
Zheng, X.2
Gilley, C.B.3
MacDonald, M.4
Okolotowicz, K.5
Cashman, J.R.6
Vyas, S.7
Beck, J.M.8
Hadad, C.M.9
Zhang, J.10
-
18
-
-
0028226772
-
Behavioral decrements persist in rhesus monkeys trained on a serial probe recognition task despite protection against soman lethality by butyrylcholinesterase
-
Castro C.A., Gresham V.C., Finger A.V., Maxwell D.M., Solana R.P., Lenz D.E., Broomfield C.A. Behavioral decrements persist in rhesus monkeys trained on a serial probe recognition task despite protection against soman lethality by butyrylcholinesterase. Neurotoxicol. Teratol. 1994, 16:145-148.
-
(1994)
Neurotoxicol. Teratol.
, vol.16
, pp. 145-148
-
-
Castro, C.A.1
Gresham, V.C.2
Finger, A.V.3
Maxwell, D.M.4
Solana, R.P.5
Lenz, D.E.6
Broomfield, C.A.7
-
19
-
-
77955512573
-
Characterization of cutaneous exposure to chemical warfare agents GD, VX and VR
-
(Abstract #478)
-
Clarkson E.D., Hackley J.P., Skvorak M., Shutz S., Schulz S., Railer R., Schons M., Macalalag R. Characterization of cutaneous exposure to chemical warfare agents GD, VX and VR. Society for Neuroscience Meeting Abstracts 2001, p. 11 (Abstract #478).
-
(2001)
Society for Neuroscience Meeting Abstracts
, pp. 11
-
-
Clarkson, E.D.1
Hackley, J.P.2
Skvorak, M.3
Shutz, S.4
Schulz, S.5
Railer, R.6
Schons, M.7
Macalalag, R.8
-
20
-
-
77955513066
-
Cutaneous exposure to GD and VX: Timing of antidotes
-
(Abstract #81)
-
Clarkson E.D., Schulz S.M., Railer R.F., Sigler M.A., Logan T.P., Baskin S.I. Cutaneous exposure to GD and VX: Timing of antidotes. The Toxicologist: 45th Annual Meeting and ToxExpo 2006, p. 17 (Abstract #81).
-
(2006)
The Toxicologist: 45th Annual Meeting and ToxExpo
, pp. 17
-
-
Clarkson, E.D.1
Schulz, S.M.2
Railer, R.F.3
Sigler, M.A.4
Logan, T.P.5
Baskin, S.I.6
-
21
-
-
47549112860
-
A novel approach to assessing percutaneous VX poisoning in the conscious guinea-pig
-
Mumford H., Price M.E., Wetherell J.R. A novel approach to assessing percutaneous VX poisoning in the conscious guinea-pig. J Appl Toxicol. 2008, 28:694-702.
-
(2008)
J Appl Toxicol.
, vol.28
, pp. 694-702
-
-
Mumford, H.1
Price, M.E.2
Wetherell, J.R.3
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