Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK

Molecular Immunology

Volumn 47, Issue 15, 2010, Pages 2485-2491

  Manarin, Romina ^a,b   Pascutti, María Fernanda ^a,b   Ruffino, Juan Pablo ^b   De Las Heras, Beatriz ^c   Boscá, Lisardo ^d   Bottasso, Oscar ^b   Revelli, Silvia ^b   Serra, Esteban ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Anti inflammatory; Chagas' disease; Immunomodulation; NF B

Indexed keywords

BENZNIDAZOLE; HYDROGEN PEROXIDE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ACTIVATION; DRUG MECHANISM; ENZYME ACTIVATION; MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

TRYPANOSOMA CRUZI;

EID: 77955512725     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.06.002     Document Type: Article

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